Varian

BRCA1 causes ovarian cancer through indirect, biochemical route

Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the University of Southern California. Their work is being published in the March 29 issue of the journal Current Biology.</p...

Human Eggs Can Develop From Ovarian Surface Cells In Vitro

Research has shown for the first time that human eggs may develop directly from cultured ovarian surface epithelium (OSE) cells derived from adult human ovaries. Oocytes derived from the culture of OSE cells developed in vitro into mature eggs suitable for fertilization and development into an embryo. These findings, published today in the Open Access journal Reproductive Biology and Endocrinolog...

Variant prion protein causes infection but no symptoms

Abnormal prion proteins are little understood disease agents involved in causing horrific brain-wasting diseases such as Creutzfeldt-Jacob disease in people, mad cow disease in cattle and chronic wasting disease in deer and elk. Now, new research suggests that a variant form of abnormal prion protein--one lacking an "anchor" into the cell membrane--may be unable to signal cells to start the letha...

Gene expression profile helps predict chemotherapy response in ovarian cancer patients

A newly identified gene expression profile could help predict how patients with advanced ovarian cancer will respond to chemotherapy treatment. Described in a study in the November 1, 2005 issue of The Journal of Clinical Oncology (JCO), the new findings further establish an important role for microarray gene profiling as a predictor of clinical outcome in ovarian cancer, and could eventually pro...

Mass. General study finds potential ovarian cancer stem cells

Massachusetts General Hospital (MGH) researchers have identified potential ovarian cancer stem cells, which may be behind the difficulty of treating these tumors with standard chemotherapy. Understanding more about the stem-like characteristics of these cells could lead to new approaches to treating ovarian cancer, which kills more than 16,000 U.S. women annually and is their fifth most common c...

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Varian at Biology Products

Excalibur 3100 from Varian, Inc.

Description:The Excalibur™ mid-, near- and far-infrared range FT-IR spectrometers give you the only truly research-grade performance in their class. Yet all this comes at an amazingly affordable price. Highest-energy throughput: Having a larger and faster mirror closer to the source compared to other conventional FT-IRs provides 300%larger solid angle of energy into the interferom...
Company:Varian, Inc.

1200 LC/MS from Varian, Inc.

Description:The high-performance triple quadrupole 1200L sets the new standard for value in today's cost-conscious environment - incorporating the latest technologies and providing tailored solutions for all liquid chromatography analytical needs. The Atmospheric Pressure Ionization (API) interface and the Transmission Quadrupole Analyzer provide superior selectivity and sensitivity for pharmaceutical, cl...
Company:Varian, Inc.

Varian 820-MS from Varian, Inc.

Description:The 820-MS features Varians unique collision reaction interface (CRI) system*, which provides simple, routine removal of troublesome spectroscopic interferences. The result is faster, more flexible interference-free analysis without the worry of complex multipole or scanning quadrupole ion guides, or cells. And, by coupling autotuning of all instrument parameters, including CRI gases, instrument...
Company:Varian, Inc.

Varian 2200 Ion Trap GC/MS from Varian, Inc.

Description:The Saturn 2200 answers your GC/MS questions with the CP-3800 GC and the 2000 Series Ion Trap MS! These components create a platform for the worlds most versatile GC and flexible MS. Both deliver unequaled performance a Saturn tradition...
Company:Varian, Inc.

500-MS LC Ion Trap from Varian, Inc.

Description:The Varian 500-MS LC Ion Trap is the instrument of choice for high-throughput LC/MS analysis where sensitivity, reliability and productivity are essential. The Varian 500-MS provides a robust platform for demanding LC/MS/MS applications. The system sensitivity, mass resolution, and mass stability reflect the ion trap technologys inherent advantages, while the new enhanced charge cap...
Company:Varian, Inc.

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Varian at Biology Technology

Using XL1-Red Mutator Strain to Generate Esterase Variants

XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...

Purification and Characterization of beta-Lactoglobulin Genetic Variants A and B Using Preparative Electrophoresis and Isoelectric Focusing

K. H. Valkonen*, N. Marttinen*, H.-L. Malinen*, V.-P. Jaakola** and T. Alatossava* * Biotechnology Laboratory, REDEC of Kajaani, University of Oulu, FIN-88600 Sotkamo, Finland ** Department of Biological and Environmental Science, University of Jyvskyl, PL 35, FIN-40351 Jyvskyl, Finland...

Detection of Apolipoprotein Gene Variants by DGGE Using the DCode System

Clive R. Pullinger, Arghavan K. Shahidi, Andrea L. Verhagen and John P. Kane Department of Biochemistry and Biophysics, University of California, San Francisco, California In a numb...

Cytosolic expression of Green Fluorescent Protein (GFP) and its derivatives in the yeast Saccharomyces cerevisiae: Detection in vivo using the Varian Cary Eclipse

Cytosolic expression of Green Fluorescent Protein (GFP) and its derivatives in the yeast Saccharomyces cerevisiae : Detection in vivo using the Varian Cary Eclipse Department of Biochemistry and Molecular Biology, Monash University,...

Monitoring fluorescence resonance energy transfer (FRET) between GFP fusions in lysates of the yeast Saccharomyces cerevisiae using the Varian Cary Eclipse

fusions in lysates of the yeast Saccharomyces cerevisiae using the Varian Cary Eclipse Department of Biochemistry and Molecular Biol...

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Varian at Biology Dictionary

Phenotypic variance

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Genetic variance

Genetic varianc...

Environmental variance

al factors (as...

Varian at Medicine News

Ovarian cancer in relationship with Hormone therapy

A major US study has found that women who have taken postmenopausal oestrogens for ten years or more are at substantially greater risk of fatal ovarian cancer. The risk persists for many years after therapy is discontinued, researchers from the American Cancer Society report// in the Journal of the American Medical Association.The study followed 201,681 postmenopausal women from 1982 t...

Progestin protects against ovarian cancer

Ovarian cancer is the most common cancer among women. It accounts for about 4 percent of all cancers in women, with more than 23,000 new cases diagnosed in 2001. Progestin is the ingredient in oral contraceptive pills that provides the highest// level of protection against ovarian cancer. Analysis by the Duke Comprehensive Cancer Center of a 20-year-old study showed that the pill can help prevent...

Inherited gene important in ovarian cancer

A gene causes significant complications in ovarian cancer. A gene implicated in inherited ovarian cancer is more significant in the disease than previously realised. Up to 10 per cent of cases of ovarian cancer arise from a mutation in a gene called BRCA1.// In these cases, the woman usually has a strong family history of the disease. We know that BRCA1 prevents tumours from developing, although...

Blood test may identify ovarian cancer

Some 23,300 American women are expected to be diagnosed with ovarian cancer every year, and the disease is expected to cause 13,900 deaths. It accounts for 4 percent of all cancers among women. A simple blood test may be able to identify ovarian cancer at its earliest stage. Currently, around three-quarters of women with ovarian cancer are diagnosed in advanced stages of the disease, when they ha...

Exercise lowers Risk of Ovarian Cancer

Research says that women have yet another good reason to exercise regularly. We know that regular exercise is good for so many things. It reduces our risk of heart disease and stroke,// and it even reduces our stress levels. Now a new study says it's also good for reducing our risk of ovarian cancer. Right now screening tests for ovarian cancer are not very appropriate. That makes it...

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Varian at Medicine Products

Variant

Description:The Variant hemoglobin testing system (110V) provides fast, accurate testing for diabetes monitoring, sickle cell screening, beta-thalassemia testing, hemoglobinopathy screening and multiple answers from a single test. It has bar code capability and is cost-effective, expandable and versatile....
Company:Bio-Rad Laboratories

Variant II

Description:The Variant II is a fully automated analyzer that requires no sample preparation and very little hands-on time by the operator. The Variant II sampling station accepts bar coded primary specimen tubes. It reads the bar code, samples from the closed tube, dilutes and injects the specimen into the chromatographic station for analysis. The results are processed by Bio-Rad's Clinical Data Management...
Company:Bio-Rad Laboratories

Variant II Total GHb Program

Description:The VARIANT II™ Total GHb Program is a fast, totally-automated and objective assay for the measurement of total glycated hemoglobin using affinity separation technology. The results are reported in standardized HbA1c values to assure traceability to DCCT....
Company:Bio-Rad Laboratories

Variant Total GHb Program

Description:The VARIANT™ Total GHb Program separates glycated hemoglobin from non-glycated hemoglobin regardless of phenotype and without interference from Schiff Base. Patient results are standardized to the DCCT reference to ensure accurate diabetes monitoring....
Company:Bio-Rad Laboratories

ultra2 A1c and Hemoglobin Variants Analyzer

Description:The ultra2 is an HPLC system designed to provide fast and accurate measurements of patient hemoglobin levels and aid in the comprehensive identification and quantitation of hemoglobin variants delivering unparalleled results for glycemic control. The A1c assay combines the speed and precision of HPLC with the accuracy of boronate affinity columns. The result is a precise assessment of tru...
Company:Primus Corporation

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Varian at Medicine Technology

Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial

LONDON, 12 July 2007 - Cancer drug developer Antisoma plc(LSE: ASM, US OTC: ATSMY) today announces new data from its phaseII trial of ASA404 in recurrent, platinum-sensitive ovarian cancer.This trial compares patients receiving ASA404 plus chemotherapy(n=37) with patients receiving chemotherapy alone (n=38). The mainfindings are as follows: * There was no advantage in median time t...

Novelos Therapeutics Announces Encouraging Results in Ongoing Phase 2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care

NEWTON, Mass.--(BUSINESS WIRE)--Jun 18, 2007 - NovelosTherapeutics, Inc. (OTCBB: NVLT), a biopharmaceutical companyfocused on the development of therapeutics to treat cancer andhepatitis, today announced encouraging results in an ongoingDana-Farber/Partners Cancer Care (DF/PCC) Phase 2 trial of NOV-002in combination with carboplatin in platinum-resistant ovariancancer patients. To date, 10...

GSK'S Pazopanib Shows Positive Results in Patients with Advanced Renal Cell Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

CHICAGO, June 04, 2007 /PRNewswire/ -- GlaxoSmithKline todayannounced results from ongoing Phase II studies of pazopanib inadvanced or metastatic renal cell carcinoma (RCC), ovarian cancerand soft tissue sarcoma (STS). These trials were presented at the43rd Annual Meeting of the American Society of Clinical Oncology(ASCO) in Chicago. The results observed in these trials withpazopanib sup...

Kosan Presents Promising Phase 1 Data on Second-Generation Hsp90 Inhibitor, Alvespimycin, Showing Antitumor Activity in Refractory Breast and Ovarian Cancers at ASCO

Clinical Benefit Shown in 35% of HER2-Positive Metastatic BreastCancer Patients HAYWARD, Calif., June 04, 2007 /PRNewswire-FirstCall/ -- KosanBiosciences Incorporated presented data from a Phase 1 clinicaltrial showing that alvespimycin, its second-generation Hsp90inhibitor, demonstrated promising antitumor activity andtolerability in combination with trastuzumab (Herceptin(R)) inpatient...

Expression Genetics, Inc. Announces Successful Completion of Phase I Trial of Gene-Based IL-12 for Treatment of Ovarian Cancer

HUNTSVILLE, Ala., April 16, 2007 /PRNewswire/ -- ExpressionGenetics, Inc., announced today the completion of a Phase Iclinical study evaluating the Company's lead drug candidate,EGEN-001. The study, conducted at The University of Alabama atBirmingham and , evaluated the safety, tolerance, preliminaryefficacy, and biological activity of the EGEN-001 in 13 patientswith advanced recurrent e...

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Varian at Medicine Dictionary

Ovarian cysts

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Ovarian cyst

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Ovarian Cancer

s. The ca...

Ovarian hypofunction

Anorchia (absense of <a href="/ ?q=/ Medicine-Dict...