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Variability in Medical News

Wide variability in rheumatoid arthritis drug suggests alternative dosing should be considered

Methotrexate (MTX) is commonly used to treat rheumatoid arthritis (RA) and is suggested as the "anchor" drug in treating the disease. Despite its widespread use, the understanding of its mechanism of action and pharmacokinetics is limited. Since joint damage occurs early in the course of RA and is...

Breaking Study: Masimo Pleth Variability Index (PVI) Shown Effective in Noninvasive Detection of Changes in Ventricular Preload and Fluid Volume

Most recent addition to Masimo Rainbow SET platform seen as having potential clinical application for the noninvasive detection of hypovolemia and fluid responsiveness monitoring SAN FRANCISCO, Oct. 15 /PRNewswire-FirstCall/ -- Masimo, the inventor of Pulse CO-Oximetry and ...

Treating depression may improve recovery of heart rate variability following coronary syndromes

Patients with depression appear to have an impaired ability to recover their heart rate variability following acute coronary syndromes such as heart attack, a factor that could increase their risk of coronary death, according to a report in the September issue of Archives of General Psychiatry, on...

Caraco Pharmaceutical Laboratories, Ltd. Announces a Nationwide Voluntary Recall of All Lots of Digoxin Tablets Due to Size Variability

DETROIT, March 31 /PRNewswire-FirstCall/ -- Caraco Pharmaceutical Laboratories, Ltd. (NYSE Amex: CPD ), a generic pharmaceutical company, announced today that all tablets of Caraco brand Digoxin, USP, 0.125 mg, and Digoxin, USP, 0.25 mg, distributed prior to March 31, 2009, which are not expired...

US Oncology Reports Second Quarter Operating Results

.... Although the interest rate swap is not accounted for as a cash flow hedge, the Company believes the swap, economically, remains a hedge against the variability of interest accruing on Holdings' indebtedness. As of June 30, 2009, the indebtedness issued by US Oncology Holdings, Inc., amounted to $475.6...

The Advisory Board Company Reports Fiscal Year 2010 First Quarter Results

... comparability without regard to changes arising from applicable tax rates, variability in interest income and foreign currency exchange rates, and periodic costs ..., risks associated with anticipating market trends, industry consolidation, variability of quarterly operating results, possible volatility in the Company's stock ...
Variability in Medical Technology

Vectibix(R) in Combination With Chemotherapy Significantly Improved Progression-Free Survival in First-Line Metastatic Colorectal Cancer

...ime that it takes for us to complete clinical trials and obtain regulatory approval for product marketing has in the past varied and we expect similar variability in the future. We develop product candidates internally and through licensing collaborations, partnerships and joint ventures. Product candidates tha...

NewCardio Announces Master Services Agreement With Dedicated Phase I

... to the FDA digital ECG warehouse with greater accuracy and lower intrinsic variability than the legacy manual or semi-automated methodologies provide. In addition...ustomers, to include both CROs and sponsors, with higher accuracy and lower variability in a more timely and cost-effective manner," said Vincent Renz, NewCardio's...

Amgen Announces Positive Top-Line Results for Denosumab in Trial for Delay of Skeletal Related Events in Bone Metastases Patients Compared to Zometa(R)

...ime that it takes for us to complete clinical trials and obtain regulatory approval for product marketing has in the past varied and we expect similar variability in the future. We develop product candidates internally and through licensing collaborations, partnerships and joint ventures. Product candidates th...

Denosumab Demonstrates Superiority Over Zometa(R) in Pivotal Phase 3 Head-to-Head Trial in Breast Cancer Patients With Bone Metastases

...ime that it takes for us to complete clinical trials and obtain regulatory approval for product marketing has in the past varied and we expect similar variability in the future. We develop product candidates internally and through licensing collaborations, partnerships and joint ventures. Product candidates th...

Accumetrics, Inc. Announces GRAVITAS Trial 50 Percent Enrolled

...ring that the VerifyNow System is shown to be an integral tool in optimizing the use of antiplatelet therapy." About GRAVITAS The concept of variability in response to antiplatelet therapy has been well established. Also being demonstrated with increased frequency is the question of whether poor respo...

New Studies Presented at European Society of Anaesthesia Further Validate Masimo PVI(TM) for Noninvasive and Continuous Fluid Monitoring

...during, and after anesthesia. Does the Pleth variability Index correlate with stroke volume variation? Res... decreased PVI.(2) Perfusion Index and Pleth variability Index After Administration of General Anesthetic A.... Kawashima, Y. Shiraishi, S. Sato. Does the Pleth variability Index correlate with stroke volume variation?. Eu...
Variability in Medical Products

Humphrey GPA Glaucoma Progression Analysys Software

Description:...nagement of glaucoma for your patients. The software applies knowledge acquired from a multi-center clinical trial, in which the actual test/retest variability of hundreds of glaucoma patients was measured. By accurately and objectively identifying progressive visual field loss in glaucoma patients, the Humph...
Company:Carl Zeiss Meditec, Inc.

SITA SWAP Field Analyzer Software

Description:... A valuable new tool for the Humphrey Field Analyzer, SITA SWAP exhibits greater dynamic range and shows less inter-test variability than Full Threshold SWAP, at the same degree of reproducibility as Full Threshold SWAP. SWAP has been shown to correlate with the earlier glaucoma dam...
Company:Carl Zeiss Meditec, Inc.

Epicardia 4000 Holter Monitoring System

Description:...0 is a hospital-grade Holter Monitoring System, equipped with the latest Epicardia software, Diogenes Arrhythmia and ST analysis algorithm, Heart Rate variability analysis and all supporting hardware and software. Facilities with an Epicardia System in place have complete control over running reports, customizin...
Company:Medicomp, Inc.

IGFBP-2 RIA Test

Description:...ues, apparently coincident with IGF-II expression [2]. Recent studies of serum IGFBP-2 levels have shown that, unlike for IGFBP-1, there is negligible variability during the day [1] and, unlike IGFBP-1 and IGFBP-3, virtually no change during puberty [3]. IGFBP-2 has also been identified in other body fluids such...
Company:Diagnostic Systems Laboratories, Inc.

IGFBP-2 ELISA Test

Description:...ues, apparently coincident with IGF-II expression [2]. Recent studies of serum IGFBP-2 levels have shown that, unlike for IGFBP-1, there is negligible variability during the day [1] and, unlike IGFBP-1 and IGFBP-3, virtually no change during puberty [3]. IGFBP-2 has also been identified in other body fluids such...
Company:Diagnostic Systems Laboratories, Inc.

IGF-II, w/ Extraction IRMA Test

Description:...GF-II concentrations increase with postnatal age showing a moderate age-related increase throughout childhood and puberty, and there is no significant variability during the day [6,7]. Serum levels of IGF-II are also dependent on GH secretion. IGF-II levels are low in GH deficiency [7], although IGF-II levels ma...
Company:Diagnostic Systems Laboratories, Inc.
Variability in Medical Definition

Ambulatory blood pressure

... Organ Damage 3 Morning Surge 4 BP variability 5 References 6 External Links ...clinical BP measurement are referred to the marked variability of BP measurement and white coat effect. see End...Dipper >20% Extreme Dipper BP variability 24 hours noninvasive ABPM monitoring allows est...
Variability in Medical Dictionary

Tyrosinemia

...ms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis. Tyrosinemia . Definition ... There is variability in age of onset, depending on the type of tyrosinemia . ... newborn screening for tyrosinemia type I is ... Transplantation also "cures" tyros...

Ptosis

..., and sometimes familial. ... Overview: A drooping eyelid is called ptosis or blepharoptosis. ... Family photographs can help determine onset or variability of the ptosis . ... Ptosis , Droopy Eyelid, Lazy Eye, Bedroom Eyes, tosis, congenital ptosis ,Cosmetic Eye Eyelid Surgery - EyePlastics (Ocul...

Macrophage

... system. ... In this study, a mouse macrophage cell line (J774 cells) was used to obtain ... The present study also demonstrated macrophage variability in the pattern of TNF ... Further, the macrophage responses observed were clearly due to P8 PGLC, as LPS ... WT L. pifanoi-infected macrophages...

Borderline Personality Disorder

... the Diagnostic and Statistical Manual of Mental Disorders that describes a prolonged disturbance of personality function characterized by depth and variability of moods. The disorder typically involves... borderline personality disorder ( ) n. A personality disorder marked by a long-standing p...

Autoimmune disorders

...autoimmune disorders , the immune system reacts to normal body tissues. ... ... systemic and organ-specific autoimmune disorders and the variability seen in these disorders . ... Autoimmune disorders are a group of more than 80 distinct ... Autoimmune disorders ; Savannah Georgia GA, So...
Variability in Biological News

Sea otter study reveals striking variability in diets and feeding strategies

SANTA CRUZ, CA--Ecologists have long observed that when food becomes scarce, animal populations exploit a wider range of food sources. So scientists studying southern sea otters at different sites in California's coastal waters were not surprised to find that the dietary diversity of the populatio...

First Whole Genome Map of Genetic Variability in Parkinson’s Disease

In findings with implications for pandemic influenza, a new study reports for the first time that a less-virulent strain of avian influenza virus can spread from poultry to humans. The research appears in the October 1 issue of The Journal of Infectious Diseases, now available online. Crossing t...

AGU journal highlights -- Aug. 6, 2009

...ocean dynamics Seasonal winds might drive current variability in the northern Indian Ocean Closely spaced fjord...59 12. Seasonal winds might drive current variability in the northern Indian Ocean Oceanographers an... that similar dynamics could drive coastal current variability in the Atlantic and Pacific oceans. The results co...

Douglas-fir, geoducks make strange bedfellows in studying climate change

...known sea surface temperatures, we can account for almost 50 percent of the variability in the instrument records," Black said. "But when we add the data from a se...y. Any methodology that improves scientists' ability to estimate their past variability is met with interest in the research community. This new study has enabled ...

Smaller than expected, but severe, dead zone in Gulf of Mexico

...se, thus reducing the area of the zone in that region," said Rabalais. "The variability we see within each summer highlights the continuing need for multiple surve...o inform long-term management decisions, but they do not include short-term variability due to weather patterns. Prior to the LUMCON cruise, NOAA's Southeast M...

Corn yield stability varies with rotations, fertility

... MADISON, WI, July 20, 2009 -- Understanding temporal variability in crop yields has implications for sustainable crop production, particularly since greater fluxes in crop yields are projected with global climate ch...
Variability in Biological Technology

Synthetech Reports First Quarter Fiscal 2010 Results

...st quarter begins in the second quarter." Management anticipates that Synthetech's revenue will continue to be volatile from period to period. variability in Synthetech's level of revenue is based primarily on its participation in large-scale customer projects and the timing of shipments arising from the...

OmniComm Systems Acquires EDC Assets of Leading Phase I Clinical Software Vendor - Logos Technologies, Ltd.

...sks and uncertainties such as the Company's ability to obtain new contracts and accurately estimate net revenues due to uncertain regulatory guidance, variability in size, scope and duration of projects, and internal issues at the sponsoring client, integration of acquisitions, competitive factors, technological...

ERT Reports Second Quarter 2009 Results

...that might cause such a difference include: unfavorable economic conditions; our ability to obtain new contracts and accurately estimate net revenues, variability in size, scope and duration of projects and internal issues at the sponsoring client; integration of future acquisitions; competitive factors; technol...

Growing Midwestern Clinical Research Organization Selects OmniComm Systems to Provide eClinical Solutions for Phase IV Studies

...sks and uncertainties such as the Company's ability to obtain new contracts and accurately estimate net revenues due to uncertain regulatory guidance, variability in size, scope and duration of projects, and internal issues at the sponsoring client, integration of acquisitions, competitive factors, technological...

SAFC Biosciences(R) Defines Hydrolysate Components That Enhance Chinese Hamster Ovary (CHO) Cell Line Protein Production

...cterization is a leading concern for biopharmaceutical manufacturers interested in mitigating risk. They desire to mitigate supply risk and production variability stemming from the use of undefined or adulterated raw materials in their process. Control of this variable enables manufacturers to design quality int...

ERT Appoints New Vice President of Project Management

...sks and uncertainties such as the Company's ability to obtain new contracts and accurately estimate net revenues due to uncertain regulatory guidance, variability in size, scope and duration of projects, and internal issues at the sponsoring client, integration of acquisitions, competitive factors, technological...
Variability in Biological Products

T7 Phage Capture Plate from Novagen

Description:...ll strip plate has a capacity of 10 9 phage per well and low non-specific binding. Phage binding is linear over two orders of magnitude. Well-to-well variability is less than 10% and stability is greater than one year when stored dry at 4°C. The T7 Phage Capture Plate can be used in a variety of binding ass...
Company:Novagen

EasyCount System from Immunicon Corp.

Description:...curately counts dead and live nucleated cells and automatically calculates cell viability, in a single test. By automating this routine function, the variability associated with the subjective interpretation of manual methods can be eliminated. Using the EasyCount ViaSure Kit, up to six tests at a time can be p...
Company:Immunicon Corp.

GST•Tag™ Antibody Plate from Novagen

Description:...s exposed. These plates have excellent binding characteristics, with a binding capacity of > 50 ng per well and low non-specific binding. Well-to-well variability is low and stability is greater than two years when stored dry at 4°C. The GST•Tag Antibody Plate can be used in a variety of assays that req...
Company:Novagen
Variability in Biological Definition

Biodiversity

...tic diversity - diversity of genes within a species. There is a genetic variability among the populations and the individuals of the same species species di...tions Earth Summit in Rio de Janeiro defined biodiversity as: The variability among living organisms from all sources, including, inter alia , terrestri...

Hardy-Weinberg principle

...ndash;50. ESP copy Pearson, K. ( 1904 ). Mathematical contributions to the theory of evolution. XI. On the influence of natural selection on the variability and correlation of organs. Philosophical Transactions of the Royal Society of London, Ser. A 200 : 1–66. Stern, C. ( 1943 ). "The Hardy&nd...

Human

...logy Culture Civilization homo (genus) , humanoid human behaviour human biology , human ecology , human evolution , human variability environmentalism space and survival world population , world hunger human rights , humanitarian , human condition , human natu...

Lyon hypothesis

... See also XY sex-determination system Dosage compensation Reference Carrel L, Willard HF. X-inactivation profile reveals extensive variability in X-linked gene expression in females. . Nature 2005;434:400-404. PMID 15772666 . Lyon MF. Gene action in the X chromosome of the mouse (Mus ...

Natural selection

...f The Origin of Species ): IF there are organisms that reproduce, and IF offspring inherit traits from their progenitor(s), and IF there is variability of traits, and IF the environment cannot support all members of a growing population, THEN those members of the population with less-adaptive tra...

Replication

...that each node have separate copy (replica) of this page. In statistics replication refers to repeated measurement of a phenomenon, so that the variability can be estimated. In science , this is a synonym for Reproducibility . ...
Variability in Biological Dictionary

Tandem repeat sequence

...ated) Variant Allele Reports. Tri-Allelic Patterns ... Use of Short Tandem Repeat Sequences to Study Mycobacterium leprae in Leprosy ... Such variability makes short tandem repeat sequences unsuitable as a general ... ...

Tandem repeat sequences

...ram to analyze DNA sequences . Nucleic Acids Res. ... Use of Short Tandem Repeat Sequences to Study Mycobacterium leprae in Leprosy ... Such variability makes short tandem repeat sequences unsuitable as a general ... ...

Polymorphisms

...ymorphisms and Variations... Single Nucleotide Polymorphisms . What is SNPs? Single Nucleotide Polymorphisms (SNPs) represent a natural genetic variability ... Online Shopping at SpotCost.com - New and used books like Human Blood Cells Consequences of Genetic Polymorphisms and Variations 2nd edition ...

Multi-locus probe

... - locus VNTR profile. A " multi - locus probe ," however, ... autoradiographs from multi - locus probes, these probes ... March 2001: "Climate variability and Valley Fever. ... Fungus, Coccidioides immitis, using the Tcim1 Transposon as a Multi - Locus Probe . ... including single- locus probe a...

Loci

... (4) Long arm Example of bands In the fields of loci [L.] plural of locus . ... Why does linkage between loci tend to decrease the amount of variability among ... When is the season finale for loci ? ... LOCI was awarded a $100,000 grant from the Great Lakes Protection Fund to ... The LOCI part...

Intragenic

... within the same gene ... Intragenic Enzyme Complementation. ... Intragenic Suppressors ... Intragenic tandem repeats generate functional variability ... We propose that variation in intragenic repeat number provides the functional ... BioInfoBank Library :: INTRAGENIC COMPLEMENTATION AMONG...
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Breaking Medicine News(10 mins):Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 2Health News:At Crist Fundraiser, Dan Newlin Says, "No More Robert Germans," Will Seek Changes to Florida Missing Persons Law 3Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 2Health News:The Advocator Group, LLC is Proud to Participate in an Out of the Darkness Community Walk, October 25th, to Increase Suicide Awareness 3Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 2Health News:OhioHealth Welcomes New Women’s Health Specialist to MaternOhio Specialists in Obstetrics & Gynecology of Columbus, Inc. 3Health News:Healthcare Relationship Management (HRM) Leader hc1.com® Launches hc1® Quick Start™ 2Health News:JZ Fitness Nutrition App Launches on iTunes 2Health News:JZ Fitness Nutrition App Launches on iTunes 3
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Breaking Biology News(10 mins):Researchers find why depression and aging linked to increased disease risk 2Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Sperm wars 2
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