Varia

Gene variations explain drug dose required to control seizures

Determining which variants of particular genes patients with epilepsy carry might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University College London. Patients often undergo a lengthy process of trial and error to find the dose of ant...

BRCA1 causes ovarian cancer through indirect, biochemical route

Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the University of Southern California. Their work is being published in the March 29 issue of the journal Current Biology.</p...

Genetic Variation Visualization - From EMBL

"Because up to 75 percent of breast cancerpatients have an abnormality in a specific cell signaling pathway,drugs that target different molecules along that pathway may beespecially effective for treating the disease, says a researcher fromThe University of Texas M. D. Anderson Cancer Center." A clearer picture is now emergingabout the importance of the phosphatidylinositol 3 kinase...

Variation in women's X chromosomes may explain differences among individuals, between sexes

The first comprehensive survey of gene activity in the X chromosomes of women has revealed an unexpected level of variation among individuals, according to new work by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and Pennsylvania State University. The results may have important implications for understanding the differences in traits among women and...

Human Eggs Can Develop From Ovarian Surface Cells In Vitro

Research has shown for the first time that human eggs may develop directly from cultured ovarian surface epithelium (OSE) cells derived from adult human ovaries. Oocytes derived from the culture of OSE cells developed in vitro into mature eggs suitable for fertilization and development into an embryo. These findings, published today in the Open Access journal Reproductive Biology and Endocrinolog...

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Varia at Biology Products

Excalibur 3100 from Varian, Inc.

Description:The Excalibur™ mid-, near- and far-infrared range FT-IR spectrometers give you the only truly research-grade performance in their class. Yet all this comes at an amazingly affordable price. Highest-energy throughput: Having a larger and faster mirror closer to the source compared to other conventional FT-IRs provides 300%larger solid angle of energy into the interferom...
Company:Varian, Inc.

1200 LC/MS from Varian, Inc.

Description:The high-performance triple quadrupole 1200L sets the new standard for value in today's cost-conscious environment - incorporating the latest technologies and providing tailored solutions for all liquid chromatography analytical needs. The Atmospheric Pressure Ionization (API) interface and the Transmission Quadrupole Analyzer provide superior selectivity and sensitivity for pharmaceutical, cl...
Company:Varian, Inc.

Varian 820-MS from Varian, Inc.

Description:The 820-MS features Varians unique collision reaction interface (CRI) system*, which provides simple, routine removal of troublesome spectroscopic interferences. The result is faster, more flexible interference-free analysis without the worry of complex multipole or scanning quadrupole ion guides, or cells. And, by coupling autotuning of all instrument parameters, including CRI gases, instrument...
Company:Varian, Inc.

Varian 2200 Ion Trap GC/MS from Varian, Inc.

Description:The Saturn 2200 answers your GC/MS questions with the CP-3800 GC and the 2000 Series Ion Trap MS! These components create a platform for the worlds most versatile GC and flexible MS. Both deliver unequaled performance a Saturn tradition...
Company:Varian, Inc.

500-MS LC Ion Trap from Varian, Inc.

Description:The Varian 500-MS LC Ion Trap is the instrument of choice for high-throughput LC/MS analysis where sensitivity, reliability and productivity are essential. The Varian 500-MS provides a robust platform for demanding LC/MS/MS applications. The system sensitivity, mass resolution, and mass stability reflect the ion trap technologys inherent advantages, while the new enhanced charge cap...
Company:Varian, Inc.

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Varia at Biology Technology

Using XL1-Red Mutator Strain to Generate Esterase Variants

XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...

Detection of Variation in Highly Polymorphic Mhc Genes by Denaturing Gradient Gel Electrophoresis Using the DCode System

Kristi M. Miller, Tobi J. Ming and Ruth E. Withler, Pacific Biological Station,Department of Fisheries and Oceans, Nanaimo, B.C. V9R 5K6, Canada Introduction We describe a rapid and sensitive method for the detection of nucleotide sequence variation which can be used for largescale screening of population...

Purification and Characterization of beta-Lactoglobulin Genetic Variants A and B Using Preparative Electrophoresis and Isoelectric Focusing

K. H. Valkonen*, N. Marttinen*, H.-L. Malinen*, V.-P. Jaakola** and T. Alatossava* * Biotechnology Laboratory, REDEC of Kajaani, University of Oulu, FIN-88600 Sotkamo, Finland ** Department of Biological and Environmental Science, University of Jyvskyl, PL 35, FIN-40351 Jyvskyl, Finland...

Using the DCode System to Identify DNA Sequence Variation for Studies of Population Structure in Marine Organisms

Patrick M. Gaffney, Elizabeth A. Orbacz, and Ziniu Yu, College of Marine Studies, University of Delaware, Lewes, Delaware. DNA polymorphisms are useful tools for ecological and evolutionary studies of both terrestrial and marine organisms, with applications ranging from s...

Detection of Apolipoprotein Gene Variants by DGGE Using the DCode System

Clive R. Pullinger, Arghavan K. Shahidi, Andrea L. Verhagen and John P. Kane Department of Biochemistry and Biophysics, University of California, San Francisco, California In a numb...

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Varia at Biology Dictionary

Variation

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Phenotypic variance

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Phase variation

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Genetic variance

Genetic varianc...

Environmental variance

al factors (as...

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Varia at Medicine News

Ovarian cancer in relationship with Hormone therapy

A major US study has found that women who have taken postmenopausal oestrogens for ten years or more are at substantially greater risk of fatal ovarian cancer. The risk persists for many years after therapy is discontinued, researchers from the American Cancer Society report// in the Journal of the American Medical Association.The study followed 201,681 postmenopausal women from 1982 t...

The Benefits Of Chemotherapy For Women With Ovarian Cancer

Researchers have found that chemotherapy improves survival and reduces the risk of recurrence in women with stage I ovarian cancer // (cancer that has not spread beyond the ovary). About one quarter of all ovarian cancers are caught while confined to the ovaries, when five-year survival is 85 percent. Most doctors may prefer not to offer chemotherapy for their patients, since eight in 10...

Progestin protects against ovarian cancer

Ovarian cancer is the most common cancer among women. It accounts for about 4 percent of all cancers in women, with more than 23,000 new cases diagnosed in 2001. Progestin is the ingredient in oral contraceptive pills that provides the highest// level of protection against ovarian cancer. Analysis by the Duke Comprehensive Cancer Center of a 20-year-old study showed that the pill can help...

Inherited gene important in ovarian cancer

A gene causes significant complications in ovarian cancer. A gene implicated in inherited ovarian cancer is more significant in the disease than previously realised. Up to 10 per cent of cases of ovarian cancer arise from a mutation in a gene called BRCA1.// In these cases, the woman usually has a strong family history of the disease. We know that BRCA1 prevents tumours from developing, a...

Variation in breast cancer

According to a new study a diet high in animal products raises the risk of breast cancer, but exposure to sunlight offers protection. Many studies have suggested a link between a high fat diet, rich in animal products, and breast cancer.// An independent researcher based in Chicago, USA, reveals that dietary differences might explain the geographical variation in breast cancer. Rates are...

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Varia at Medicine Products

Variant

Description:The Variant hemoglobin testing system (110V) provides fast, accurate testing for diabetes monitoring, sickle cell screening, beta-thalassemia testing, hemoglobinopathy screening and multiple answers from a single test. It has bar code capability and is cost-effective, expandable and versatile....
Company:Bio-Rad Laboratories

Variant II

Description:The Variant II is a fully automated analyzer that requires no sample preparation and very little hands-on time by the operator. The Variant II sampling station accepts bar coded primary specimen tubes. It reads the bar code, samples from the closed tube, dilutes and injects the specimen into the chromatographic station for analysis. The results are processed by Bio-Rad's Clinical Data Management...
Company:Bio-Rad Laboratories

Headband headlight system (10-75 mm variable spot)

Description:It provides excellent illumination from an inexpensive platform and is mounted on the comfortable UltraLite headband....
Company:Luxtec Corporation

Cauterette I, Variable low temperature handle (requires disposable tips)

Description:Accu-Temp Cauteries provide a broad selection of tip styles for cauterization in a wide variety of ophthalmic procedures. Each single use cautery is packaged sterile, complete with a safety cap to lock switch in the "off " position when not in use, a...
Company:Medtronic Xomed, Inc.

Novus Varia

Description:The Worlds First Solid-State Three-Color Photocoagulator.Retinal physicians throughout the world have chosen to purchase over 3,000 Lumenis multi-color photocoagulators.For the retinal specialist with a busy practice, the Novus Varia integrates green, yellow, and red solid-state,diode-pumped lasers into a single, compact system that supports your treatment of a diverse range of patients....
Company:Lumenis Inc.

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Varia at Medicine Technology

Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.

The FDA approval of BiDil for heart failure in African American patients has underscored the concept that two patients can respond differently to the same medication. This concept holds true for a wide variety of everyday medications, and in many cases is due to individual gen...

Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial

LONDON, 12 July 2007 - Cancer drug developer Antisoma plc(LSE: ASM, US OTC: ATSMY) today announces new data from its phaseII trial of ASA404 in recurrent, platinum-sensitive ovarian cancer.This trial compares patients receiving ASA404 plus chemotherapy(n=37) with patients receiving chemotherapy alone (n=38). The mainfindings are as follows: * There was no advantage in median time t...

Novelos Therapeutics Announces Encouraging Results in Ongoing Phase 2 Ovarian Cancer Trial at Dana-Farber/Partners Cancer Care

NEWTON, Mass.--(BUSINESS WIRE)--Jun 18, 2007 - NovelosTherapeutics, Inc. (OTCBB: NVLT), a biopharmaceutical companyfocused on the development of therapeutics to treat cancer andhepatitis, today announced encouraging results in an ongoingDana-Farber/Partners Cancer Care (DF/PCC) Phase 2 trial of NOV-002in combination with carboplatin in platinum-resistant ovariancancer patients. To date, 10...

GSK'S Pazopanib Shows Positive Results in Patients with Advanced Renal Cell Carcinoma, Ovarian Cancer and Soft Tissue Sarcoma

CHICAGO, June 04, 2007 /PRNewswire/ -- GlaxoSmithKline todayannounced results from ongoing Phase II studies of pazopanib inadvanced or metastatic renal cell carcinoma (RCC), ovarian cancerand soft tissue sarcoma (STS). These trials were presented at the43rd Annual Meeting of the American Society of Clinical Oncology(ASCO) in Chicago. The results observed in these trials withpazopanib sup...

Kosan Presents Promising Phase 1 Data on Second-Generation Hsp90 Inhibitor, Alvespimycin, Showing Antitumor Activity in Refractory Breast and Ovarian Cancers at ASCO

Clinical Benefit Shown in 35% of HER2-Positive Metastatic BreastCancer Patients HAYWARD, Calif., June 04, 2007 /PRNewswire-FirstCall/ -- KosanBiosciences Incorporated presented data from a Phase 1 clinicaltrial showing that alvespimycin, its second-generation Hsp90inhibitor, demonstrated promising antitumor activity andtolerability in combination with trastuzumab (Herceptin(R)) inpatient...

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Varia at Medicine Dictionary

Ovarian cysts

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Ovarian cyst

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Ovarian Cancer

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Ovarian hypofunction

Anorchia (absense of <a href="/ ?q=/ Medicine-Dict...