Gene variations explain drug dose required to control seizures
Determining which variants of particular genes patients with epilepsy carry might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University College London. Patients often undergo a lengthy process of trial and error to find the dose of ant...BRCA1 causes ovarian cancer through indirect, biochemical route
Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the University of Southern California. Their work is being published in the March 29 issue of the journal Current Biology.</p...Genetic Variation Visualization - From EMBL
"Because up to 75 percent of breast cancerpatients have an abnormality in a specific cell signaling pathway,drugs that target different molecules along that pathway may beespecially effective for treating the disease, says a researcher fromThe University of Texas M. D. Anderson Cancer Center." A clearer picture is now emergingabout the importance of the phosphatidylinositol 3 kinase...Variation in women's X chromosomes may explain differences among individuals, between sexes
The first comprehensive survey of gene activity in the X chromosomes of women has revealed an unexpected level of variation among individuals, according to new work by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and Pennsylvania State University. The results may have important implications for understanding the differences in traits among women and...Human Eggs Can Develop From Ovarian Surface Cells In Vitro
Research has shown for the first time that human eggs may develop directly from cultured ovarian surface epithelium (OSE) cells derived from adult human ovaries. Oocytes derived from the culture of OSE cells developed in vitro into mature eggs suitable for fertilization and development into an embryo. These findings, published today in the Open Access journal Reproductive Biology and Endocrinolog...Excalibur 3100 from Varian, Inc.
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Description:The Varian 500-MS LC Ion Trap is the instrument of choice for high-throughput LC/MS analysis where sensitivity, reliability and productivity are essential. The Varian 500-MS provides a robust platform for demanding LC/MS/MS applications. The system sensitivity, mass resolution, and mass stability reflect the ion trap technologys inherent advantages, while the new enhanced charge cap...Using XL1-Red Mutator Strain to Generate Esterase Variants
XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...Ovarian cancer in relationship with Hormone therapy
A major US study has found that women who have taken postmenopausal oestrogens for ten years or more are at substantially greater risk of fatal ovarian cancer. The risk persists for many years after therapy is discontinued, researchers from the American Cancer Society report// in the Journal of the American Medical Association.The study followed 201,681 postmenopausal women from 1982 t...The Benefits Of Chemotherapy For Women With Ovarian Cancer
Researchers have found that chemotherapy improves survival and reduces the risk of recurrence in women with stage I ovarian cancer // (cancer that has not spread beyond the ovary). About one quarter of all ovarian cancers are caught while confined to the ovaries, when five-year survival is 85 percent. Most doctors may prefer not to offer chemotherapy for their patients, since eight in 10...Progestin protects against ovarian cancer
Ovarian cancer is the most common cancer among women. It accounts for about 4 percent of all cancers in women, with more than 23,000 new cases diagnosed in 2001. Progestin is the ingredient in oral contraceptive pills that provides the highest// level of protection against ovarian cancer. Analysis by the Duke Comprehensive Cancer Center of a 20-year-old study showed that the pill can help...Inherited gene important in ovarian cancer
A gene causes significant complications in ovarian cancer. A gene implicated in inherited ovarian cancer is more significant in the disease than previously realised. Up to 10 per cent of cases of ovarian cancer arise from a mutation in a gene called BRCA1.// In these cases, the woman usually has a strong family history of the disease. We know that BRCA1 prevents tumours from developing, a...Headband headlight system (10-75 mm variable spot)
Description:It provides excellent illumination from an inexpensive platform and is mounted on the comfortable UltraLite headband....Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.
The FDA approval of BiDil for heart failure in African American patients has underscored the concept that two patients can respond differently to the same medication. This concept holds true for a wide variety of everyday medications, and in many cases is due to individual gen...Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
LONDON, 12 July 2007 - Cancer drug developer Antisoma plc(LSE: ASM, US OTC: ATSMY) today announces new data from its phaseII trial of ASA404 in recurrent, platinum-sensitive ovarian cancer.This trial compares patients receiving ASA404 plus chemotherapy(n=37) with patients receiving chemotherapy alone (n=38). The mainfindings are as follows: * There was no advantage in median time t...