Epilepsy Drug Valproate and Lamotrigine Linked To Malformed Fetus
In a study in the March issue of Neurology, the epilepsy drug Valproate has been linked to malformation of fetus //when prescribed to pregnant ladies. For pregnant women with epileptic seizures, often the drug Valproate is prescribed. The new study shows that women who took the drug in their first trimester of pregnancy often gave birth to malformed babies. Data for the st...Mode Of Action Of The Anti-Convulsant Valproate
Researchers from Australia have recently shown, using a yeast-based in vitro bioassay for steroid hormones that valproate, a commonly used anti-convulsant for the treatment of epilepsy and bipolar disorder, is an anti-androgen and anti-progestin. // Anti-convulsant treatment is associated with a high prevalence of reproductive dysfunction compared with age-matched non-epileptics. <b...