Navigation Links
VEGFR in Medical News

Bayer to Present Data on Development Compound BAY 73-4506 at 45th Annual Meeting of the American Society of Clinical Oncology

... (TK). BAY 73-4506 has been shown to inhibit tumor growth in preclinical models by hitting targets along a spectrum of angiogenic pathways, including vegfr and TIE2. BAY 73-4506 has also been shown to prevent the proliferation of tumor cell lines while promoting apoptosis (cell death) by directly targeti...

Abbott to Present Data on Novel Cancer Treatments at American Society of Clinical Oncology Annual Meeting

...molecule that provides simultaneously potent and specific inhibition of the vegfr and PDGFR families. Both compounds were discovered by Abbott scientists and...molecule that provides simultaneously potent and specific inhibition of the vegfr and PDGFR families that is in Phase I clinical trials for solid tumors and ...
VEGFR in Medical Technology

Bayer Announces New Data on Novel Anti-cancer Compound BAY 73-4506

...TK). In preclinical studies, BAY 73-4506 has been shown to inhibit tumor growth by hitting targets along a spectrum of angiogenic pathways, including vegfr and TIE2. BAY 73-4506 has also been shown in preclinical studies to prevent the proliferation of tumor cell lines while promoting apoptosis (cell dea...

Millennium Presents New Data on Investigational Drugs for Novel Cancer Targets at EORTC-NCI-AACR Symposium

...a. -- Unique enzymatic profile of a potent and selective BEGFR/PDGFR tyrosine kinase inhibitor, TAK-593: potent pseudo-irreversibility against vegfr and PDGFR -- Lead investigator: H. Miki, Takeda Pharmaceutical Company, Japan -- Abstract #50: Poster -- TAK-593, a potent and selectiv...

Exelixis Reports XL647 Clinical Data at AACR-NCI-EORTC Conference

...24 /PRNewswire-FirstCall/ -- Exelixis, Inc. (Nasdaq: EXEL ) today reported updated data from a phase 2 study of XL647, an inhibitor of EGFR, HER2 and vegfr kinases, in previously untreated, clinically selected non-small cell lung cancer (NSCLC) patients. The data continue to show encouraging anti-tumor ac...

Updated Phase 1 Data for Exelixis' XL184 Demonstrate Pharmacodynamic and Clinical Anti-Tumor Activity

...stCall/ -- Exelixis, Inc. (Nasdaq: EXEL ) today reported encouraging data from an ongoing phase 1 trial of XL184, a potent inhibitor of MET, RET, and vegfr kinases, in patients with advanced solid tumors or lymphoma. Anti-tumor activity has been observed in a variety of cancers at doses that are not assoc...

New Data for XL880, XL647 and XL184 to Be Presented at AACR-NCI-EORTC

...se-escalation study of the safety and pharmacokinetics (PK) of XL184, a vegfr and MET kinase inhibitor, administered orally to patients (pts) with ad...y of the safety, pharmacokinetics (PK) and pharmacodynamics of XL880, a vegfr and MET kinase inhibitor, administered daily to patients (pts) with adv...

Ascenta Therapeutics Highlights Multiple Data Presentations at Upcoming AACR Annual Meeting

...orally active pan-Bcl-2 family Zhang, MD, protein inhibitor in combination PhD with dual-Raf/MEK and vegfr Ascenta kinase inhibitor sorafenib Therapeutics (Nexavar(R)) --------- --------- ----------...

New Data Show Pfizer's Axitinib Prolonged Overall Survival in Advanced Pancreatic Cancer When Combined with Standard of Care Chemotherapy

... that axitinib (AG-013736), an investigational oral, selective inhibitor of vegfr 1, 2,3 (vascular endothelial growth factor receptors 1, 2, 3) combined with...t yet known. About Axitinib Axitinib is an oral, selective inhibitor of vegfr 1, 2, 3 (vascular endothelial growth factor receptors 1, 2 and 3), which ha...
VEGFR in Biological Technology

Telik Reports Preclinical Results at AACR Annual Meeting

...echanism of Action of Orally Active Aurora Kinase/ vegfr Inhibitors; Abstract # 1764 Aurora kinases are ...ong and equipotent inhibition of Aurora kinase and vegfr kinase, with IC50s less than 10 nM. These ...dule. Drug inhibition of aurora kinase and vegfr activity in tumor samples of treated animals was e...

Telik's Aurora Kinase-VEGFR Dual Inhibitor Program Meets a Preclinical Development Milestone

... PALO ALTO, Calif., Aug. 21 /PRNewswire-FirstCall/ -- Telik, Inc. (Nasdaq: TELK ) announced today that the lead compounds of its Aurora kinase and vegfr dual inhibitor program met a significant development milestone. Aurora kinase is a critical signaling enzyme whose function is required for cancer cel...
Other Tags
(Date:10/31/2014)... central to life. The last stage, when two daughter ... the dawn of cell biology in the Victorian era. ... to study this final step, when the dividing cell ... name given to this process by those early biologists, ... of a highly active and organized series of events. ...
(Date:10/31/2014)... its kind, Rice University researchers have mapped how information ... to become metastatic. The research reveals a common pattern ... migrate and form new tumors. Researchers say the commonality ... with the genetic switches that cancer must flip to ... -- two of the main players in cancer metastasis. ...
(Date:10/31/2014)... Friday. October 31, 2014 — A team from ... and the University of California, Santa Cruz, was ... Cancer Genomics Cloud Pilot contracts with the goal ... analysis of The Cancer Genome Atlas (TCGA) and ... required computing resources in one cloud environment. This ...
(Date:10/31/2014)... Daily Gossip writes in its Xtreme Fat Loss ... fastest fat loss program ever developed. It promises to provide ... There is no wonder after all that this has become ... new nutrition and workout fat loss program was created by ... According to the author of this fat loss system, the ...
(Date:10/31/2014)... (PRWEB) October 31, 2014 This ... has amazing health effects for practitioners. , ... a Doctor of Science and Movement specializing in ... dedication to pelvic floor reeducation that traditional abdominal ... incontinence, Diastasis Recti, Prolepses, etc. , The Hipopressives ...
Breaking Medicine News(10 mins):Health News:Cell division, minus the cells 2Health News:Cell division, minus the cells 3Health News:Decoding the emergence of metastatic cancer stem cells 2Health News:Decoding the emergence of metastatic cancer stem cells 3Health News:Broad Institute, Univ. of California team awarded NCI Cancer Genomics Cloud Pilot contract 2Health News:Broad Institute, Univ. of California team awarded NCI Cancer Genomics Cloud Pilot contract 3Health News:Xtreme Fat Loss Diet Review Reveals How to Transform Your Body in 25 Days 2Health News:Super Models and European Celebrities’ Secret Flat Tummy System Comes to America 2Health News:Super Models and European Celebrities’ Secret Flat Tummy System Comes to America 3
(Date:10/31/2014)... largest producer of cocoa. Chocolate trees ( Theobroma cacao ... of rainforest in the state of Bahia, beneath a ... rainforest was a biodiversity hotspot, the chocolate trees, which ... in the mid 1700s, had very low levels of ... scenario created a very romantic, but extremely fragile situation". ...
(Date:10/31/2014)... 2014 – Dr. John Schoggins , Assistant Professor ... a prestigious New Innovator Award from the National Institutes ... why bats can harbor numerous viruses without becoming sick. ... five years is one of 85 awards given under ... Common Fund. The New Innovator Awards were created to ...
(Date:10/31/2014)... of Adelaide-led project has developed a new test that ... the H5N1 strain of avian influenza virus or "bird ... This is a significant step in the fight against ... widespread in the poultry populations of South East Asia, ... because of its possible transmission to humans and the ...
Breaking Biology News(10 mins):Scientists seek cure for devastating witches' broom disease of the chocolate tree 2Scientists seek cure for devastating witches' broom disease of the chocolate tree 3UT Southwestern Microbiologist awarded prestigious NIH research grant 2New step towards eradication of H5N1 bird flu 2
Other Contents