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VDR in Medical News

UCSF Researchers Use New Tools to Move in on Cancer Susceptibility Genes

...lty Vitamin D Receptor gene have also been associated with the propensity for various types of cancer in people and mice. "Now we have shown vdr can be linked to skin cancer in mice using genetic network analysis methods," says Balmain. Because man and mouse share significant similarities...

Study helps clarify role of vitamin D in cancer therapy

...show that vitamin D's genomic and nongenomic effects integrate to regulate cell physiology. One question the researchers now want to pursue is whether vdr from different locationsthe nucleus, the cytosol, and possibly the cell membranehas different functions in the pathway. ...

Cytochroma Announces Positive Comparative Data on CTA018 in Chronic Kidney Disease Model

... clinical studies with CTA018 Injection." The newly disclosed data support the following four conclusions regarding CTA018: (1) CTA018 is a Potent vdr Agonist and CYP24 Inhibitor CTA018 is a dual action active vitamin D analog. Like currently approved vitamin D therapies for SHPT, CTA018 is a poten...

Too much coffee is too bad

...ounces of brewed coffee per day or 32 ounces of brewed tea-is not associated with increased bone loss.Until it is practical to determine each person’s vdr genotype, physicians should recommend both adequate dietary calcium and moderate caffeine comsumption for their elderly patients. ...
VDR in Medical Products

Affinity™ VDR Pacemaker

Description: The Affinity pacemaker family offers some of today's smallest, truly automatic devices. Featuring the most effective combination of advanced technologies ever seen, the Affinity DR pacemaker incorporates the exclusive ventricular AutoCapture Pacing Systems, assuring Beat-by-Beat capture....
Company:St. Jude Medical, Inc.

AV Plus DX Single-Pass Pacing Leads

Description:... The AV Plus DX pacing lead is designed for use with the St. Jude Medical Affinity vdr pulse generator. This single-lead pacing system provides reliable pacing therapy with the added benefits of AV synchrony and minimized intravascular h...
Company:St. Jude Medical, Inc.

AV Plus DX Single-Pass

Description:... The AV Plus DX pacing lead is designed for use with the St. Jude Medical Affinity vdr pulse generator. This single-lead pacing system provides reliable pacing therapy with the added benefits of AV synchrony and minimized intravascular h...
Company:St. Jude Medical, Inc.
VDR in Biological News

Vitamin D may exacerbate autoimmune disease

...nce associated solely with calcium metabolism, the vdr is now known to transcribe at least 913 genes and ...Marshall and team explain that by deactivating the vdr and subsequently the immune response, 25-D lowers ...levels are naturally down-regulated in response to vdr dysregulation by chronic pathogens. Under such ci...

Could vitamin D save us from radiation?

...ich allows gene transcription to take place and the activation of the innate immune response. It is possible that several of the transcribed by the vdr will help transcribe proteins that protect the body against radiation. "Vitamin D by its preventive/ameliorating actions should be given serious co...

Genes linked to treatment resistance in children with leukemia

...rain" barrier that protects the CNS. For patients in the high-risk arm, the vdr FokI genotype was found to be prognostic for CNS relapse, especially when combined with a vdr intron 8 genotype. In the low-risk group, the TYMS 3/3 genotype was a risk ...
VDR in Biological Products

Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

Description:...y detects a 58 kDa and 60 kDa protein representing vdr in avians while the VDRs of mammalian species appe... 52-55 kDa range. Immunohistochemical staining of vdr in cultured human skin fibroblasts with MA1-710 re...gulation, and differentiation. Studies have found vdr in the intestine, bone, kidney, epidermis, and cel...
Company:ABR-Affinity BioReagents
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(Date:9/17/2014)... Mich. Mutations in the human retinoblastoma protein gene ... State University scientists have turned to fruit fly eyes ... , In a paper featured on the cover ... Biological Chemistry , Michigan State University researchers provide the ... to those present in the human cancer gene, said ...
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