VCU Researchers Identify Networks Of Genes Responding To Alcohol In The Brain
Virginia Commonwealth University researchers have identified several genetic changes in the brains of mice caused by ethanol, which may help researchers better understand how and why people become addicted to alcohol. In the March issue of the Journal of Neuroscience, researchers reported significant differences in the gene expression patterns regulated by alcohol in two mouse strains know...VCU study shows hormone-like molecule kills cells that cause inflammation in allergic disease
Virginia Commonwealth University immunologists studying mast cells, known to play a central role in asthma and allergic disease, have identified a hormone-like molecule that can kill these cells by programming them to die in studies with mice. The findings move researchers another step closer to understanding the life cycle of mast cells, and may help researchers develop new treatments fo...VCU Massey Cancer Center study shows enzyme linked to spread of breast cancer cells
Researchers at the Virginia Commonwealth University Massey Cancer Center have found a new signaling component that influences movement of human breast cancer cells toward epidermal growth factor. In the August issue of the Journal of Biological Chemistry, researchers showed that epidermal growth factor, which plays a critical role in breast cancer progression, stimulates sphingosine kinase...VCU Massey Cancer Center researchers identify a new class of anti-cancer drugs based on platinum
Researchers at Virginia Commonwealth University's Massey Cancer Center have created a new platinum-based, anti-cancer agent able to overcome acquired drug resistance by first modifying the way it is absorbed into cancer cells and then attacking the DNA of those cancer cells. The findings may help researchers design a new generation of anti-cancer drugs that selectively target cancer cells...