Variant

Variant prion protein causes infection but no symptoms

Abnormal prion proteins are little understood disease agents involved in causing horrific brain-wasting diseases such as Creutzfeldt-Jacob disease in people, mad cow disease in cattle and chronic wasting disease in deer and elk. Now, new research suggests that a variant form of abnormal prion protein--one lacking an "anchor" into the cell membrane--may be unable to signal cells to start the letha...

UCSD researchers discover variants of natural tumor suppressor

Building on their 2005 discovery of an enzyme that is a natural tumor suppressor, researchers at the University of California, San Diego (UCSD) School of Medicine have now identified two variants of that enzyme which could provide new targets for therapies to treat diabetes, heart and neurological disease. The findings, by Alexandra C. Newton, Ph.D., UCSD professor of pharmacology, and colleague...

Identified main genetic variants involved in response to HIV

This international collaboration has been the largest ever to have taken place in a large scale study on genetic differences between patients infected by HIV, and is the first study of this kind in the field of infectious disease. Catalan participants have been coordinated by Javier Martínez-Picado, ICREA research professor in the Foundation irsiCaixa of Hospital Germans Trias i Pujol, and Jos...

Variant at Biology Products

Rabbit Anti-mu Opioid Receptor splice variant Antibody, Unconjugated from ABR-Affinity BioReagents

Description:mu Opioid Receptor splice variant -20 C, Avoid Freeze/Thaw Cycles...
Company:ABR-Affinity BioReagents

Variant at Biology Technology

Using XL1-Red Mutator Strain to Generate Esterase Variants

XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...

Purification and Characterization of beta-Lactoglobulin Genetic Variants A and B Using Preparative Electrophoresis and Isoelectric Focusing

K. H. Valkonen*, N. Marttinen*, H.-L. Malinen*, V.-P. Jaakola** and T. Alatossava* * Biotechnology Laboratory, REDEC of Kajaani, University of Oulu, FIN-88600 Sotkamo, Finland ** Department of Biological and Environmental Science, University of Jyvskyl, PL 35, FIN-40351 Jyvskyl, Finland...

Detection of Apolipoprotein Gene Variants by DGGE Using the DCode System

Clive R. Pullinger, Arghavan K. Shahidi, Andrea L. Verhagen and John P. Kane Department of Biochemistry and Biophysics, University of California, San Francisco, California In a numb...

Variant at Medicine News

Gene variant foretells diabetic neuropathy

A gene variant that is linked to an increase in the risk of Alzheimer's disease also predicts which people with diabetes are most likely to suffer neuropathy. In diabetes, impaired circulation may cause neuropathy in the lower limbs - that is, //peripheral nerve damage leading to pain and numbness. In severe cases, amputation may even be necessary. Researchers at Duke University in the US have no...

Gene Variants Linked to Early Heart Attack Discovered

Two gene variations have been discovered by scientists at UCSF, Celera Genomics and The Cleveland Clinic which have been linked to an increased risk// for early heart attack, or myocardial infarction (MI). One of the genes, known as VAMP8, normally expresses a protein essential for early stages of clotting. When clotting occurs in a coronary blood vessel, it can lead to heart attack. Kn...

Sugar variant may make a world of difference to Alzheimers disease

A novel study by Canadian researchers has revealed that variants of a sugar, is found to improve Alzheimers disease in mice//. Though these studies are still in ithe nascent stages, these findings could mean better methods of treatment to manage Alzheimers and even offset the onslaught. A type of sugar, termed as cyclohexanehexol, or inositol did not cause the collection of amyloid a...

Striking a Gold Mine: H5N1 Vaccine may Serve as an Antidote for Mutants and Variants

As a breather and news that spells heaven for millions of avian influenza patients there is a research by scientists at St. Jude Children’s Research Hospital //. According to them they have developed in the lab a vaccine that is potent against one antigenic variant of the avian influenza virus H5N1. The scientific discovery is that this vaccine also has the ability to protect humans against futur...

Susceptibility Of TB In Humans Might Be Due To Three Human Gene Variants

A new study has reported that there appears to be three variations of a human gene that seem to cause an impact on humans upon their susceptibility towards tuberculosis// . Researchers hope that these findings would provide sufficient knowledge as to why some patients infected with the Mycobacterium tuberculosis pathogen develop the full-blown disease while others are seemingly not affected. The...

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Variant at Medicine Products

Variant

Description:The Variant hemoglobin testing system (110V) provides fast, accurate testing for diabetes monitoring, sickle cell screening, beta-thalassemia testing, hemoglobinopathy screening and multiple answers from a single test. It has bar code capability and is cost-effective, expandable and versatile....
Company:Bio-Rad Laboratories

Variant II

Description:The Variant II is a fully automated analyzer that requires no sample preparation and very little hands-on time by the operator. The Variant II sampling station accepts bar coded primary specimen tubes. It reads the bar code, samples from the closed tube, dilutes and injects the specimen into the chromatographic station for analysis. The results are processed by Bio-Rad's Clinical Data Management...
Company:Bio-Rad Laboratories

Variant II Total GHb Program

Description:The VARIANT II™ Total GHb Program is a fast, totally-automated and objective assay for the measurement of total glycated hemoglobin using affinity separation technology. The results are reported in standardized HbA1c values to assure traceability to DCCT....
Company:Bio-Rad Laboratories

Variant Total GHb Program

Description:The VARIANT™ Total GHb Program separates glycated hemoglobin from non-glycated hemoglobin regardless of phenotype and without interference from Schiff Base. Patient results are standardized to the DCCT reference to ensure accurate diabetes monitoring....
Company:Bio-Rad Laboratories

ultra2 A1c and Hemoglobin Variants Analyzer

Description:The ultra2 is an HPLC system designed to provide fast and accurate measurements of patient hemoglobin levels and aid in the comprehensive identification and quantitation of hemoglobin variants delivering unparalleled results for glycemic control. The A1c assay combines the speed and precision of HPLC with the accuracy of boronate affinity columns. The result is a precise assessment of tru...
Company:Primus Corporation

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Variant at Medicine Technology

ACC Presentation Indicates Interleukin-1 Gene Variants Determine Increased Risk for Coronary Artery Disease from Oxidized Phospholipids

WALTHAM, Mass.--(BUSINESS WIRE)--Mar 27, 2007 - InterleukinGenetics, Inc. (AMEX:ILI) and collaborators at the University ofCalifornia San Diego today reported at the American College ofCardiology annual meeting that associations between coronary arterydisease (CAD) and both oxidized phospholipids (OxPL) and Lp(a)levels appear to be dependent on pro-inflammatory variants of theinterleukin-1...