Gene variations explain drug dose required to control seizures
Determining which variants of particular genes patients with epilepsy carry might enable doctors to better predict the dose of drugs necessary to control their seizures, suggest basic findings by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and the University College London. Patients often undergo a lengthy process of trial and error to find the dose of ant...BRCA1 causes ovarian cancer through indirect, biochemical route
Mutated BRCA1 genes cause ovarian cancer indirectly, by interfering with the biochemical signals one ovarian cell sends to another, according to a team of researchers led by scientists at the USC/Norris Comprehensive Cancer Center and the Keck School of Medicine of the University of Southern California. Their work is being published in the March 29 issue of the journal Current Biology.</p...Genetic Variation Visualization - From EMBL
"Because up to 75 percent of breast cancerpatients have an abnormality in a specific cell signaling pathway,drugs that target different molecules along that pathway may beespecially effective for treating the disease, says a researcher fromThe University of Texas M. D. Anderson Cancer Center." A clearer picture is now emergingabout the importance of the phosphatidylinositol 3 kinase...Variation in women's X chromosomes may explain differences among individuals, between sexes
The first comprehensive survey of gene activity in the X chromosomes of women has revealed an unexpected level of variation among individuals, according to new work by researchers at the Duke University Institute for Genome Sciences & Policy (IGSP) and Pennsylvania State University. The results may have important implications for understanding the differences in traits among women and...Human Eggs Can Develop From Ovarian Surface Cells In Vitro
Research has shown for the first time that human eggs may develop directly from cultured ovarian surface epithelium (OSE) cells derived from adult human ovaries. Oocytes derived from the culture of OSE cells developed in vitro into mature eggs suitable for fertilization and development into an embryo. These findings, published today in the Open Access journal Reproductive Biology and Endocrinolog...Excalibur 3100 from Varian, Inc.
Description:The Excalibur™ mid-, near- and far-infrared range FT-IR spectrometers give you the only truly research-grade performance in their class. Yet all this comes at an amazingly affordable price. Highest-energy throughput: Having a larger and faster mirror closer to the source compared to other conventional FT-IRs provides 300%larger solid angle of energy into the interferom...Varian 820-MS from Varian, Inc.
Description:The 820-MS features Varians unique collision reaction interface (CRI) system*, which provides simple, routine removal of troublesome spectroscopic interferences. The result is faster, more flexible interference-free analysis without the worry of complex multipole or scanning quadrupole ion guides, or cells. And, by coupling autotuning of all instrument parameters, including CRI gases, instrument...Varian 2200 Ion Trap GC/MS from Varian, Inc.
Description:The Saturn 2200 answers your GC/MS questions with the CP-3800 GC and the 2000 Series Ion Trap MS! These components create a platform for the worlds most versatile GC and flexible MS. Both deliver unequaled performance a Saturn tradition...Interspecies Trial Array 3: N Pancreas, N Skin, N Spleen, N Ovary from CHEMICON
Description:Chemicon Select Tissue Arrays are intended for laboratory research use only. The individual tissues were fixed in neutral buffered formalin and embedded in paraffin. Tissue identification and diagnosis was performed by certified pathologists. Tissue cores were removed from their paraffin blocks and relocated into a new recipient paraffin block, in an array pattern, using Chemicons Advanced Tis...Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance
Stratagene We introduce six pairs of control RT-PCR primers that are designed todetect specific human gene transcripts with various expression levels. Theseprimer sets provide insight into whether cDNA synthesis has been effective forall ab...Using XL1-Red Mutator Strain to Generate Esterase Variants
XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...Tools for Detecting MSH2 Expression in Chinese Hamster Ovary Cells
Stratagene Streamline RNA analysis with a whole host of products from Stratagene.First, the StrataPrep total RNA miniprep kit isused to isolate ample yields of high-quality RNA from tissues and cells, thenthe RNA is r...Higher gDNA Concentrations with the Perfect gDNA Blood Mini Kit by Varying the Final Elution Volume
by Varying the Final Elution Volume Eppendorf 5 Prime, Boulder, Colorado Perfect gDNA Blood Mini Kit protocol recommend...Higher gDNA Concentrations with the Perfect gDNA Blood Mini Kit by Varying the Final Elution Volume
by Varying the Final Elution Volume Eppendorf 5 Prime, Boulder, Colorado Perfect gDNA Blood Mini Kit protocol recommend...Ovarian cancer in relationship with Hormone therapy
A major US study has found that women who have taken postmenopausal oestrogens for ten years or more are at substantially greater risk of fatal ovarian cancer. The risk persists for many years after therapy is discontinued, researchers from the American Cancer Society report// in the Journal of the American Medical Association.The study followed 201,681 postmenopausal women from 1982 t...Novartis files application with FDA for Zometa
Novartis Pharmaceuticals has submitted an application to the Food and Drug Administration, seeking marketing authorization for Zometa in the treatment of bone complications associated with a broad range of tumor types. These include prostate and lung cancer, for which no bisphosphonate therapy is currently approved. The spread of cancerous cells from the original tumor to the bone, can le...The Benefits Of Chemotherapy For Women With Ovarian Cancer
Researchers have found that chemotherapy improves survival and reduces the risk of recurrence in women with stage I ovarian cancer // (cancer that has not spread beyond the ovary). About one quarter of all ovarian cancers are caught while confined to the ovaries, when five-year survival is 85 percent. Most doctors may prefer not to offer chemotherapy for their patients, since eight in 10...Harvard Proposes Drug Disposal Plan
Harvard Medical School has reported that more care has to be taken while disposing unused and expired medicines. Harvard advices public to start disposing old medicines as old medicines looses its pharmacological action overtime//. Proper disposal of old medicines has to be done as disposing them in toilets or dust bins can lead to development of antibiotic resistance in environmental mic...Progestin protects against ovarian cancer
Ovarian cancer is the most common cancer among women. It accounts for about 4 percent of all cancers in women, with more than 23,000 new cases diagnosed in 2001. Progestin is the ingredient in oral contraceptive pills that provides the highest// level of protection against ovarian cancer. Analysis by the Duke Comprehensive Cancer Center of a 20-year-old study showed that the pill can help...Zaldivar forceps for Acrylic lens
Description:Thin and smooth jaws, designed to enter trough 3 mm incision, cross action....Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.
The FDA approval of BiDil for heart failure in African American patients has underscored the concept that two patients can respond differently to the same medication. This concept holds true for a wide variety of everyday medications, and in many cases is due to individual gen...Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
LONDON, 12 July 2007 - Cancer drug developer Antisoma plc(LSE: ASM, US OTC: ATSMY) today announces new data from its phaseII trial of ASA404 in recurrent, platinum-sensitive ovarian cancer.This trial compares patients receiving ASA404 plus chemotherapy(n=37) with patients receiving chemotherapy alone (n=38). The mainfindings are as follows: * There was no advantage in median time t...