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Urokinase in Medical News

ImaRx Therapeutics Submits Urokinase Data to FDA Supporting Extended Expiration Dating

Stability Testing Meets Specifications Results Support Expiration Date Extension TUCSON, Ariz., Dec. 21 /PRNewswire-FirstCall/ -- ImaRx Therapeutics, Inc. (Nasdaq: IMRX ) today announced that it has submitted a lot release request to the Food and Drug Administra...

Enzyme Urokinase Better Option In Empyema For Kids

Researchers say that enzyme urokinase provides a better option as a treatment for empyema in children since it is 25 percent less costlier than another treatment// video-assisted thoracoscopic surgery. The researchers say both methods are equally effective. The study results appear in the sec...

JCI online early table of contents: March 9, 2009

...ulated mice, Peter Carmeliet and his colleagues at Katholieke Universiteit Leuvan, Belgium, reveal in a new study that a membrane-anchored form of the urokinase receptor known as MuPAR is present on a subset of HSPCs and helps maintain this cell population in the bone marrow. When MuPAR was deleted or inh...

Elevated biomarkers predict risk for prostate cancer recurrence

...lar endothelial growth factor, vascular cell adhesion molecule-1, endoglin, urokinase plasminogen activator. "We reviewed background literature over 60 separ...ere associated with increased risk of relapse. For example, the presence of urokinase plasminogen inhibitor-1 increased risk by 37 percent, while the presence of...

Targeted Anticancer Drugs - In Vitro Assessment and Non-Invasive Imaging of Patient and Tumor Status Will Determine Clinical and Commercial Success

...ein (P-gp); phosphatidylinositol 3`kinase (PI3K); phosphatidyserine (PS); PI3K, catalytic, delta polypeptide (PI3KCD); PIK3C2A; plasminogen activator, urokinase (PLAU); polo-like kinase 1 (Plk1); poly (ADP- ribose) polymerase (PARP); programmed cell death-1 (PDCD1); prostate specific antigen (PSA); prostate st...

Fruit fly protein acts as decoy to capture tumor growth factors, find Penn researchers

...that is similar in structure to Argos. Intriguingly, Argos shares structural similarities with the human receptors for transforming growth factor and urokinase plasminogen activator. "There are quite a few other human proteins with similar predicted structures whose function is not yet known," says Lemmon. "W...

Receptor protein appears to be key in breakdown of kidney filtration

...ty, the researchers focused their attention on molecules known to be associated with cellular motility in a number of situations. One of these is the urokinase receptor (uPAR), which is known to be involved in wound healing and inflammation, as well as tumor invasion and metastasis. Reisers team found tha...
Urokinase in Medical Technology

ImaRx Therapeutics Transitions Business Strategy

... Focuses on Commercial Product urokinase and Evaluates Strategic Alternatives for...oday that it will emphasize growing the market for urokinase in contrast to its previous focus on developing So...tems which provides for manufacture of a long term urokinase supply and will allow the company to explore addit...
Urokinase in Biological News

Tips from the American Journal of Pathology

...reduce the lung injury that accompanies oxygen therapy." van Zoelen MAD, Florquin S, de Beer R, Pater JM, Verstege MI, Meijers JCM, van der Poll T: urokinase plasminogen activator receptor-deficient mice demonstrate reduced hyperoxia-induced lung injury. Am J Pathol 2009, 174: 2182-2189 AM80 Block...

Friend or foe? How the body's clot-busting system speeds up atherosclerosis

...ogically speaking. Naturally produced in the body, urokinase plasminogen activator and plasminogen interact to ...lear away debris related to inflammation. In fact, urokinase manufactured as a drug effectively clears clogged ... plasminogen. However, despite the efficacy of urokinase and plasmin in clearing blood clots, evidence has ...

Analysis of breast-cancer gene role offers promising target

...or of the study, said the biochemical process triggered by uPAR, called the urokinase plasminogen activator system, is one of the breast-cancer prognostic factor...o address HER-2-positive breast cancer with drugs that block both HER-2 and urokinase given together." The study opens a promising avenue to increase the ef...
Urokinase in Biological Technology

ImaRx Therapeutics Receives Urokinase Lot Release Approval With Extended Expiration Dating

TUCSON, Ariz., Jan. 25 /PRNewswire-FirstCall/ -- ImaRx Therapeutics, Inc. (Nasdaq: IMRX ) today announced that the Food and Drug Administration (FDA) has approved the company's most current lot release request for urokinase drug product. This is the first lot to be released with extended expi...

ImaRx Therapeutics Signs Letter of Intent With Microbix Biosystems for the Sale of Urokinase

Microbix to Acquire Commercialized Thrombolytic and Related Assets for $17 Million TUCSON, Ariz., May 7 /PRNewswire-FirstCall/ -- ImaRx Therapeutics, Inc. (Nasdaq: IMRX ) today announced that it has signed a letter of intent in which Microbix Biosystems will acqu...

ImaRx Therapeutics Satisfies Abbott Note Obligation Associated With the Acquisition of Urokinase

TUCSON, Ariz., April 23 /PRNewswire-FirstCall/ -- ImaRx Therapeutics, Inc. (Nasdaq: IMRX ) today announced that it has entered into an agreement with Abbott Laboratories pursuant to which it has satisfied its obligations under its $15 million non-recourse promissory note with Abbott issued in...

Microbix Sales Grow 22% For Nine Months

...artificial insemination companies worldwide." urokinase The Company acquired all urokinase assets from ImaRx Therapeutics, Inc. of Tucson, Ar...ember 2008. These assets included ImaRx' remaining urokinase inventory as well as the regulatory file for the p...

Microbix Sales Grow Over 30% In The Second Quarter; Up 43% In The First Half '09

...ing non-dilutive ways to advance the product. urokinase The Company acquired all urokinase assets from ImaRx Therapeutics, Inc. of Tucson, Ar...ember 2008. These assets included ImaRx' remaining urokinase inventory as well as the regulatory file for the p...

Microbix First Quarter Sales Grow Over 50% With Continued Progress On The Pipeline

...DA to authorize release of Kinlytic inventory, our urokinase product, we are in discussions with potential phar...imelines through field trials and to market". urokinase The Company acquired all urokinase assets from ImaRx Therapeutics, Inc. of Tucson, Ar...

Microbix Uses Core Business Cashflow To Fund Late-Stage Pipeline To Build Shareholder Value In 2009

...Fiscal 2009 will be a pivotal year as we re-launch urokinase and seek partnership for our Hunan (China) influen... built a solid patent foundation in 2008. urokinase The Company's $2.5 million acquisition of all urokinase assets from ImaRx Therapeutics, Inc. of Tucson, Ar...

ImaRx Therapeutics Reports First Quarter Ended 2008 Financial Results

...y note issued in connection with the Company's urokinase acquisition. -- Signed letter of intent to sell urokinase inventory and related assets to Microbix Biosy... of its core SonoLysis program upon closing of urokinase divestiture with Microbix Biosystems. Bradfo...

ImaRx Therapeutics Reports Business Update and Financial Results for Fourth Quarter and Full Year 2007

...linical study -- Received FDA approval to market urokinase under new trade name Kinlytic(TM) -- Signed...ips Electronics -- Extended expiration dating of urokinase product inventory Key Corporate Highlights: Pha...e significant value from our SonoLysis program." urokinase Business Update Urokinase, the Company's first F...

ImaRx to Report Corporate Updates and 4Q07 Financial Results

... sales of and demand for urokinase may decline, the FDA may not approve our future requests for urokinase lot releases or approval of expanded uses of urokinase beyond treatment of acute massive pulmonary emboli, we may not be able to complete definitive documentation with Microbix on the terms of our letter o...
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