Neuronal 'traffic jam' marks early Alzheimer's disease
Early Alzheimer's disease may be precipitated by a "traffic jam" within neurons that causes swelling and prevents proper transport of proteins and structures in the cells, according to new studies by Howard Hughes Medical Institute researchers. In mouse models of Alzheimer's disease and in human brain samples from people with the disease, researchers observed a characteristic breakdown in...First 'atlas' of key brain genes could speed research on cancer, neurological diseases
Researchers at Dana-Farber Cancer Institutehave compiled the first atlas showing the locations of crucial generegulators, or switches that determine how different parts of the braindevelop ?and, in some cases, develop abnormally or malfunction.The scientists say the map will accelerate research on brain tumors andneurological diseases that result from mutations in these switch genes?called...New research questions basic tenet of neuron function
New findings by researchers at UT Southwestern Medical Center challenge one of the established views of how nerve cells communicate with one another. Every time we move, feel emotions, think or remember, the nerve cells, or neurons, in our body transmit messages to one another via chemical signals called neurotransmitters. Within neurons are tiny organelles called synaptic vesicles that s...First real-time view of developing neurons reveals surprises, say Stanford researchers
Scientists have believed that neurons need a long period of fine-tuning and training with other neurons before they take on their adult role. But after using new technology for the first time to watch these cells develop, a team of researchers at the Stanford University School of Medicine found that neurons come into this world with a good idea about what they'll become as adults. The work...Antibiotic might fight HIV-induced neurological problems
By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body. Five monkeys infected with simian immunodeficiency virus (SIV), a very close relative of HIV, and treated wi...NeuroCyte - Rat Neural Stem Cell Kit from Orion BioSolutions, Inc.
Description:Rat Neural Stem Cell Kit with Medium High quality ready-to-use cryopreserved neural stem cells (NCSs) complete with optimized base medium for growth and lineage commitment. Just thaw and plate these unique cells generated from E18 fetal rat brain in the format you need for a tissue-like mixture of in vitro stem/progenitor cells, neurons, astrocytes and oligodendrocytes. Better than neurospheres...Mouse Dopaminergic Neuron Differentiation Kit, 2nd Generation from R&D Systems
Description:Reagents for the differentiation of mouse embryonic stem cells to dopaminergic neurons. Dopamine cell bodies exist in the midbrain, where they are mainly located in the substantia nigra, the ventral tegmental area, and the retrorubral field. These dopaminergic (DA) neurons give rise to extensive forebrain dopamine innervation ( e.g.projections to the caudate nucleus, putamen nucleus accumbens,...Digital Clamp One from myNeuroLab.com
Description:The Digital Clamp One can operate as a Voltage Clamp, as a Current Clamp or as a Conductance (Dynamic) Clamp in electrophysiology research applications. Performance in any one mode is as good as conventional analog equipment. This amazing instrument is made possible by very recent advances in the capabilities of Digital Signal Processing (DSP) integrated circuit chips. Until very recently, DSP...Superfusion System, Raiteri's Method from myNeuroLab.com
Description:Neurotransmitters are stored within neurons in vesicles called synaptosomes. Synaptosomes are concentrated in the synaptic bouton. Synaptosomes may be centrifuged and isolated from other cellular debris. Abnormalites in neurotransmitter release have been proposed in many pathological condtions. Conditions of release may be studied in isolated synaptosome preparations.The Superfusion System o...Vibratome 800 - McIllwain Tissue Chopper - 230V CE from myNeuroLab.com
Description:The Vibratome Company has joined forces with the Mickle Laboratory Engineering Company to introduce the Vibratome 800 Tissue Chopper. This tissue sectioning system has been designed to prepare sections of tissue for metabolic experiments and to be especially applicable to small and irregular specimens available at biopsy or from small organs. Its special features cause much less disturbance of ce...Sex Steroid Regulation of Vasopressin Levels Secreted by hNT Neurons*
N.Y. Zachariah Department of BiomedicalSciences, University of North Texas Health Science Center This article...hNT BlueNeurons Express b-Galactosidase at High Levels
-Galactosidase at HighLevels Layton BioScience, Inc. Gilroy, California Stratagene's hNT BlueNeurons express beta-galactosidase at h...Efficient Transfection of Neurospora Crassa
Katherine A. Borkovich PhD, University of Texas-Houston Medical Center, Dept. of Microbiology and Molecular Genetics, Houston, Texas. Kimberly Vollmer, Brinkmann Instruments Inc., BioSystems Application Lab, Westbury, New York....Efficient Transfection of Neurospora Crassa
Katherine A. Borkovich PhD, University of Texas-Houston Medical Center, Dept. of Microbiology and Molecular Genetics, Houston, Texas. Kimberly Vollmer, Brinkmann Instruments Inc., BioSystems Application Lab, Westbury, New York....Actinobacillus pleuropneumoniae
Actinobacillus pleuropneumo...New Drug in Diabetic Neuropathy
Diabetic Neuropathy can be a painful condition which is a very agonizing nighttime pain seen in diabetics. However, new hope lies with experimental drug, memantine, which blocks NMDA receptors, which are believed to mediate pain effects in diabetic neuropathy being researched by Central Arkansas Research, Arkansas. This drug showed a definite reduction of pain compared to placebo....Developmental, neurologic problems common in extremely preterm infants
Extremely preterm infants born before 25 weeks' gestation often have severe neurologic and developmental disabilities, researchers report in the August 10th issue of The New EnglandJournal of Medicine.The EPICure Study Group identified 308 children born at the gestational age of 25 weeks or earlier in the UK and Ireland. Of these, 283 were assessed for neurologic function Based on their l...Evidence Links Protein Damage to Neurodegenerative diseases like Parkinson's and Alzheimer's
Neurodegenerative diseases - including Parkinson's, Alzheimer's, Diffuse Lewy body disease, and Multiple System Arophy - are collectively called synucleinopathies. Most commonly they become symptomatic due to a deficiency of a specific neurotransmitter - in the case of Parkinson's it is dopamine. When the neurons that produce these chemicals die or become impaired, which occurs with oxida...Scottish Children Have Worst Dental Health In Europe
A new research has found that Scotland's kids continue to have the worst dental health in Europe with over 75 percent of the country's overall dental problems found in children aged less than five years.// The NHS has taken serious note of this and has asked parents to start their kids off on healthy dental habits at an early age to prevent dental decay. It is generally accepted that de...Vitamin D Deficiency On Rise Among Europeans
According to a Belgian researcher, nearly half of the British population are affected by vitamin D deficiency, which may lead them to an increased risk of osteoporosis or some other forms of cancer.// Roger Bouillon of the University of Leuven in Belgium told the European Congress of Endocrinology in Glasgow, Scotland, he had been studying 20 years of data -- and found that about half th...Neuro-Patch Synthetic Dura Substitute
Description:Neuro-Patch is a non-absorbable dura substitute, manufactured from highly purified polyesterurethane. Its microporous structure allows the proliferation of fibroblast, supporting tissue in-growth; the dense "weave" minimizes suture channels, resulting in decreased chance of cerebrospinal fluid leakage....Neuroview Rigid Body Fiberoptic Neuroendoscopes
Description:Low Profile Ergonomic Design for Neurosurgery. The Neuroview family of neuroendoscopes offers rigid working channel scopes with a 90 steerable tip. The rigid scope body facilitates a direct, controlled approach to the target. The steerable tip allows access to structures unreachable via a straight trajectory....Neuroview 1.2 mm Neuroendoscopes
Description:Patented* Design for Endoscopic Shunt Placement. Designed to pass through standard shunt ventricular catheters for optically guided placement....Neurologix to Present at the Third Annual C.E. Unterberg Towbin Emerging Growth Conference
FORT LEE, N.J.--(BUSINESS WIRE)--Jul 6, 2007 - Neurologix, Inc.(OTCBB:NRGX), a biotechnology company engaged in the development ofinnovative gene therapies for the brain and central nervous system,announced today that the company will present at the Third AnnualC.E. Unterberg Towbin Emerging Growth Conference on Tuesday July10, 2007 at 4:30 pm ET at The Mandarin Oriental Hotel in New York.<...Positive ZIO-201 Interim Phase II Sarcoma Data Presented at European Society for Medical Oncology
LUGANO, Switzerland--(BUSINESS WIRE)--Jul 9, 2007 - ZIOPHARMOncology, Inc. (NASDAQ: ZIOP) announces that positive interim datafrom an ongoing phase II trial of ZIO-201 (isophosphoramide mustard- IPM) to treat advanced sarcoma patients was presented at theEuropean Society of Medical Oncology (ESMO) meeting held July 5-8,2007 in Lugano, Switzerland. The abstract entitled, "Phase-I/IIStudy of...Neurobiological Brain Disorder
Many illnesses categorized as psychiatric disorders have a neurobiological basis and are sometimes referred to as "neuropsychiatric diso...European Prospective Investigation into Cancer and Nutrition
and <a href="/ ?q=...