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Uricase in Medical News

Savient Pharmaceuticals Receives Complete Response Letter from U.S. Food and Drug Administration for KRYSTEXXA(TM)

... ABOUT KRYSTEXXA (TM) KRYSTEXXA(TM) (pegloticase) is a PEGylated uricase enzyme intended for the treatment of chronic gout in patients refractory to...has developed one product: KRYSTEXXA(TM) (pegloticase) which is a PEGylated uricase enzyme intended for the treatment of chronic gout in patients refractory to...
Uricase in Medical Technology

Savient Pharmaceuticals Announces Acceptance of Two Gout-Related Abstracts for Poster Presentation at the European League Against Rheumatism (EULAR) 2007 Annual Congress

...niversity ("Duke") of North Carolina and Mountain View Pharmaceuticals, Inc. ("MVP"), a California corporation. Duke developed the recombinant porcine uricase enzyme and MVP developed the PEGylation technology. MVP and Duke were granted U.S. and foreign patents covering the licensed technology. Puricase is a...
Uricase in Biological Technology

FDA Appointed Arthritis Advisory Committee Recommends U.S. Food and Drug Administration Approval for KRYSTEXXA(TM) for Refractory Chronic Gout

...tee appointed by the U.S. Food and Drug Administration (FDA) recommended by a vote of 14 to 1 that KRYSTEXXA(TM) (pegloticase), a biologic PEGylated uricase enzyme, be granted marketing approval by the FDA for the treatment of refractory chronic gout. Refractory chronic gout or treatment failure gout (TFG...
Uricase in other areas

Urate oxidase - Wikipedia, the free encyclopedia

Urate oxidase. From Wikipedia, the free encyclopedia (Redirected from Uricase) ... Urate oxidase, also known as uricase, is a homotetrameric enzyme containing four ...

Gout Treatment - Uricase-peg 20 - EnzymeRx

Treatment for Chronic Gout using EnzymeRx's Uricase-peg 20 ... Our patented formulation of pegylated uricase is designed to have a long half ...

Gout Treatment - Uricase and Uricase-peg 20 - EnzymeRx

Treatment for Chronic Gout using EnzymeRx's Uricase-peg 20 ... The safety profile of uricase-PEG 20 was excellent in this single dose phase I study. ...

Pfam: Family: Uricase (PF01014)

Pfam is a large collection of protein families, represented by multiple sequence alignments and ... Uricase is a protein of 300 to 400 amino acids, its ...

Uricase - Worthington Enzyme Manual

Uricase (urate oxidase) catalyzes the following overall reaction: ... Uricase is very important for the determination of uric acid in biological fluids. ...

PEG-uricase

Parenteral uricase is thus a potential means of controlling hyperuricemia and ... Diabetes insipidus in uricase-deficient mice: a model for evaluating therapy ...
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