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Uric in Medical News

The Gout & Uric Acid Education Society (GUAES) Announces New Survey Results Highlighting Major Gaps in Public Awareness of Gout

New Findings Released on the Third Annual Gout Awareness Day (May 22) NEW YORK, May 22 /PRNewswire/ -- The Gout & Uric Acid Education Society announced today that new survey results reveal alarming gaps in the public's awareness of gout, a painful and potentially debilitating form of ar...

C8 Science Panel Completes Uric Acid Study

PARKERSBURG, W. Va., Jan. 27 /PRNewswire/ -- The C8 Science Panel has completed a new study on uric acid and C8 and C8S, based on existing data from the C8 Health Project. While increased uric acid is associated with higher levels of C8 and C8S, the data are not sufficient to show that these chemi...

NBA Coach Maurice Cheeks Teams Up with the Gout & Uric Acid Education Society (GUAES) to Call a 'Time Out for Gout'

Coach Cheeks partners with rheumatology experts on Gout Awareness Day to share his story and correct misperceptions about a serious condition NEW YORK, May 22 /PRNewswire/ -- Philadelphia 76ers head coach and four-time NBA All-Star Maurice Cheeks is partnering with the Gout & Uric Acid Educat...

AUA 2008: Uric acid stones may indicate arteriosclerotic diseases

ORLANDO, FL, May 20, 2008 Patients with metabolic syndrome disorders, including diabetes and high cholesterol, may be more likely to develop uric-acid stones than other type of calculi, according to research presented today at the 103rd Annual Scientific Meeting of the American Urological Associat...

Savient Pharmaceuticals Receives Complete Response Letter from U.S. Food and Drug Administration for KRYSTEXXA(TM)

...ic gout in patients refractory to conventional therapy. Gout refractory to conventional therapy occurs in patients who have failed to normalize serum uric acid and whose signs and symptoms are inadequately controlled with xanthine oxidase inhibitors at the maximum medically appropriate dose or for whom t...

Experts Lay to Rest Long-Held Misconceptions About High Fructose Corn Syrup at ILSI-USDA Workshop

... sugar (or sucrose) have differing effects on satiety, overall energy balance, metabolic hormones or biochemical metabolites such as triglycerides and uric acid - all suggesting no unique causal role for high fructose corn syrup in obesity. According to Suzanne P. Murphy, Ph.D., R.D., research profes...
Uric in Medical Technology

Phase III Trial Results Show Elitek(R) (rasburicase) Significantly Reduced Plasma Uric Acid Levels versus Allopurinol in Adults with Hematologic Cancers at Risk for Tumor Lysis Syndrome

- Results Presented at ASH Annual Meeting- SAN FRANCISCO, Dec. 6 /PRNewswire-FirstCall/ -- Sanofi-aventis today announced results of a randomized phase III study presented at the 50th Annual Meeting of the American Society of Hematology. The study in adult patients with hematological mali...

Savient Provides Update on Pegloticase BLA

...loticase can be detected within the first 4 months through monitoring serum uric acid in normal medical practice patterns. A lack of uric acid response correlates with high levels of antibody production. The Compa...

New Study Shows PCR and FCR Have Significant Activity in B-cell Chronic Lymphocytic Leukemia

...gic Malignancies Jeffrey Matous, M.D., Rocky Mountain Cancer Centers-Midtown: Superiority of Rasuburicase vs. Allopurinol on serum uric acid control in adult patients with hematologic malignancies at risk of developing Tumor Lysis Syndrome Multiple Myeloma ...

Arthritis Advisory Committee Recommends FDA Approval of Febuxostat for the Treatment of Hyperuricemia in Patients With Gout

...s studied for its ability to lower levels of serum uric acid in patients with hyperuricemia associated with gout. Hyperuricemia, elevated uric acid levels in the body, is associated with gout, ... symptoms, and diarrhea. About Gout and uric Acid ...

Ardea Biosciences Presents Preclinical Anti-Inflammatory Data on its Lead MEK Inhibitor, RDEA119, at the ACG 2008 Annual Meeting

...valuated in a Phase 1 clinical trial and is believed to be an inhibitor of the URAT1 transporter in the kidney, which is responsible for regulation of uric acid levels. We are evaluating our lead MEK inhibitor, RDEA119, in a Phase 1 study in advanced cancer patients, and have completed a Phase 1 study in ...

Ardea Biosciences to Present Data on Lead MEK Inhibitor, RDEA119, at American College of Gastroenterology Annual Scientific Meeting

...valuated in a Phase 1 clinical trial and is believed to be an inhibitor of the URAT1 transporter in the kidney, which is responsible for regulation of uric acid levels. We are evaluating our lead MEK inhibitor, RDEA119, in a Phase 1 study in advanced cancer patients, and have completed a Phase 1 study in ...
Uric in Medical Products

Infinity Uric Acid (Powder)

Description: The Infinity Uric Acid powder reagent once reconstituted offers the laboratory all the convenience of single liquid stability to help maximize laboratory productivity, minimize operator error and provide quick result turnaround time. The proprietary technology of the Infinity Uric Acid powder reage...
Company:ThermoFisher Scientific

Infinity Uric Acid (Liquid)

Description: The Infinity Uric Acid single liquid stable reagent offers the laboratory all the convenience of single liquid stability to help maximize laboratory productivity, minimize operator error and provide quick result turnaround time. The proprietary technology of the Infinity Uric Acid reagent provides ...
Company:ThermoFisher Scientific

Uric Acid (UA) Liquid

Description:... URCA (Uric acid) method used on the Dimension clinical chemistry system is an in vitro diagnostic test intended for the quantitative determination of uric acid in serum, plasma and urine....
Company:Randox Laboratories Ltd.

Uric Acid (UA)

Description:... For the quantitative in vitro determination of uric Acid in serum, plasma and urine...
Company:Randox Laboratories Ltd.

StatStrip Glucose Monitoring System

Description:...only one well. Novas exclusive Multi-Well system measures and corrects hematocrit interference as well as interferences from acetaminophen (Tylenol), uric acid, ascorbic acid (Vitamin C), maltose, galactose, xylose, and lactose. StatStrip also eliminates oxygen interference to provide accurate glucose r...
Company:Nova Biomedical

Uric Acid (Liquid) Reagent Set

Description:... For the quantitative determination of uric acid in serum....
Company:Teco Diagnostics

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Uric in Medical Dictionary

Uric acid

... uric acid is the end product of purine metabolism ...purines are building blocks of RNA and DNA). Most uric acid produced in the body is excreted by the ki...outWhat Are the Treatments for Polyarticular Gout? uric Acid Levels in ... If I have high levels of...

Pseudogout

...is. ... But in pseudogout , the crystals are formed from a salt instead of uric acid. ... Pseudogout is a form of arthritis that causes pain, stiff.... ... Unlike in gout, people with pseudogout do not develop hard lumps of uric acid crystals (tophi) ... Answers to your questions about pseudogout...

Nephrolithiasis

...ming a kidney stone, a stone in the kidney ... Nephrolithiasis . Intravenous pyelogram (IVP) Lithotripsy procedure ... Cameron MA, Sakhaee K. uric acid nephrolithiasis . Urol Clin North Am. 2007;34(3):335-346. ... Calcium stones are clearly the most commonly occuring form of nephrolithias...

Kidney stones

...he first kidney stone and asymptomatic nephrolithiasis in adults. uric ... Kidney stones are hard, solid particles that form in the urinary tract. ... uric acid is responsible for close to 10% of kidney stones . ... Types of ...

Hyperuricemia

... Hyperuricemia is a level of uric acid in the blood that is abnormally high. In ...hyperuricemia will actually develop gout. ... uric acid is the final product of purine metabolism ...n human beings. Hyperuricemia is a high level of uric acid in the blood. What drugs may be prescri...

Gout

...t is a disease hallmarked by elevated levels of uric acid in the bloodstream. In this condition, crystals of monosodium urate (MSU) or uric acid are deposited on the articular cartilage ...thritis, its causes such as high-purine diet and uric acid, its symptoms of pain, swelling, and inflamma...
Uric in Biological News

Experts lay to rest long-held misconceptions about high fructose corn syrup at ILSI-USDA workshop

... sugar (or sucrose) have differing effects on satiety, overall energy balance, metabolic hormones or biochemical metabolites such as triglycerides and uric acid all suggesting no unique causal role for high fructose corn syrup in obesity. According to Suzanne P. Murphy, Ph.D., R.D., research professor...

Seabird ammonia emissions contribute to atmospheric acidity

... climate change on ecosystem function." According to Chief Editor Peter Brimblecombe, this study is "fascinating in the context that birds excrete uric acid unlike mammals, where excreted urea is readily converted to ammonia. Ammonia is the only major alkaline gas in the atmosphere and has a major eff...

Too much fructose could leave dieters sugar shocked

...s part of the equation, UF researchers say. Eating too much fructose causes uric acid levels to spike, which can block the ability of insulin to regulate ho...gy in the UF College of Medicine. UF researchers first detailed the role of uric acid on insulin resistance and obesity in a 2005 study in rats. Certain...

Simple home spit test to spot deadly pre-eclampsia

...-eclampsia, problems with high blood pressure may not occur until the latter stages. The new test works by monitoring levels of urate, a salt of uric acid, increased levels of which are thought to be due to impaired kidney excretion in pre-eclampsia. 'A salivary urate test is simple, non-invasi...

Studies force new view on biology of flavonoids

...served after the consumption of flavonoid-rich foods is not caused by the flavonoids themselves, Frei said, but most likely is the result of increased uric acid levels. But just because flavonoids have been found to be ineffectual as antioxidants in the human body does not mean they are without value...

New player in commitment to life as a fat cell

... for its role in producing the metabolic byproduct uric acid, XOR had earlier been implicated in gout, sai...t is a painful type of arthritis that results when uric acid crystals build up in the joints. "These ...in association with the catabolism of purines into uric acid, the production of reactive oxygen species, a...
Uric in Biological Technology

FDA Appointed Arthritis Advisory Committee Recommends U.S. Food and Drug Administration Approval for KRYSTEXXA(TM) for Refractory Chronic Gout

... treatment of refractory chronic gout. Refractory chronic gout or treatment failure gout (TFG) is gout in patients who have failed to normalize serum uric acid and whose signs and symptoms are inadequately controlled with conventional urate-lowering therapy at the maximum medically appropriate dose or fo...

FDA Approves ULORIC(R) (febuxostat) for the Chronic Management of Hyperuricemia in Patients with Gout

...ith gout a new treatment option that helps prevent uric acid production," said Nancy Joseph-Ridge, M.D., p...nic gout is the reduction and maintenance of serum uric acid levels of less than 6 mg/dL. ULORIC, a xanthi...dase inhibitor, effectively lowers levels of serum uric acid in patients with hyperuricemia associated wit...

BioCryst Reports Third Quarter 2008 Financial Results and Provides Corporate Update

...counts. The pharmacokinetic and pharmacodynamic results suggest that BCX-4208 may have utility in diseases dependant on T-cells, B-cells or uric acid. The Phase 2a results have been accepted for presentation at the 50th American Society of Hematology Annual Meeting and Exposition (AS...

Savient's Pegloticase Data in Treatment-Failure Gout Patients Presented at 72nd Annual Meeting of the American College of Rheumatology Conference

...y endpoint relating to the normalization of plasma uric acid, for pegloticase 8 mg intravenous infusion ev...lling treatment effect not only for the control of uric acid, but more importantly for the amelioration of...s the GOUT 1 and GOUT 2 studies (Gout Outcomes and uric Acid Treatment) and the OLE Study is known as GOUT...

Ardea Biosciences to Present at the UBS Global Life Sciences Conference and the Third Annual JMP Securities Healthcare Focus Conference

...valuated in a Phase 1 clinical trial and is believed to be an inhibitor of the URAT1 transporter in the kidney, which is responsible for regulation of uric acid levels. We are evaluating our lead MEK inhibitor, RDEA119, in a Phase 1 study in advanced cancer patients, and have completed a Phase 1 study in ...

Ardea Biosciences to Present Data on Gout and Inflammation Programs at the 2008 ACR/ARHP Annual Scientific Meeting

...:00 a.m. PDT Abstract Title: RDEA594, A Potential uric Acid Lowering Agent through Inhibition of uric Acid Reuptake, Shows Better Pharm...the kidney, which is responsible for regulation of uric acid levels. We are evaluating our lead MEK inhibi...
Uric in Biological Products

Mouse Anti-Human Xanthine Oxidase / Aldehyde Oxidase Ab-2 Mouse Monoclonal Antibody, Biotin Conjugated, Clone 145.4 from Lab Vision

Description:... In normal tissues this enzyme exists predominantly as XDH which converts hypoxanthine and xanthine to uric acid, a critical plasma antioxidant. During ischemia, XDH is reversibly converted to the oxygen radical producing XO by oxidation of essential sulfhy...
Company:Lab Vision
Uric in Biological Definition

Enzyme

...osinase Urease : hydrolizes urea into carbon dioxide and ammonia Xanthine oxidase : oxidizes hypoxanthine to xanthine and further to uric acid Purification Since enzymes are proteins , enzyme purification begins with protein purification . Each step in the purification procedu...

Excretion

...iruses , amoebae , and various parasitic worms . Urine, on the other hand, contains excess water, salt, and protein waste in the form of urea as uric acid, and seldom any pathogens; should a person be in a situation of insufficient water and in danger of overheating due to lack of persperation, urin...

Osmoregulation

... and is generally converted to less toxic substances after it is produced then excreted; mammals convert ammonia to urea while birds and reptiles form uric acid to be excreted with other wastes via their cloacas. How osmoregulation is achieved in vertebrates Four processes occur: filtration -...

Protein

...ic substance. It is then converted in the liver into urea , a much less toxic chemical, which is excreted in urine . Some animals convert it into uric acid instead. Protein nutrition in humans In terms of human nutritional needs, proteins come in two forms: complete proteins contain all ei...

Purine

...ral enzymes , including xanthine oxidase , into uric acid . High levels of uric acid can predispose to gout when the acid crysta...intrinsic urease enzyme that can further degrade uric acid. The deficiency of another enzyme, adenosine...

Urea cycle

...ic than ammonia, therefore organisms which can't easily and quickly remove ammonia usually have to convert it to some other substance, like urea or uric acid . Insufficiency of the urea cycle occurs in some genetic disorders ( inborn errors of metabolism ), and in liver failure . The result in liver...
Uric in Biological Dictionary

Uric acid

... uric acid (or urate) is an organic compound of carbo...xygen and hydrogen with the formula C5H4N4O3. uric acid n. A semisolid compound, C 5 H 4 N 4 O 3 ,... metabolism and is the chief nitrogenous High uric acid level — Overview covers definition, possib...

Purine

.... Dietary purines are converted into serum uric acid (which is can cause gout when ... Purine r...rine bases are guanine (G) and adenine (A). uric acid, the offending substance in ... Get inform...) ... MODERATELY HIGH IN PURINES (100 to 400 mg. uric acid/100g) Bean, seed, white, dry ... A purine...

Kidney

.... KIDNEY STONES OVERVIEW Kidney stones (also called nephrolithiasis or ... The first kidney stone and asymptomatic nephrolithiasis in adults. uric acid nephrolithiasis ... ...

Backcross

...tians cannot be AKC registered nor shown in conformation at ... Normal uric Acid Dalmatians also known as Low uric Acid Dalmatians & Backcross Dalmatians ... The "Dalmatian Backcross ...
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