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Unstable in Medical News

Chemists Discover Cation Considered Too Unstable To Exist

Organic chemistry textbooks will need to be revised to recognize a chemical species that chemists have discovered. The species - pentamethylcyclopentadienyl cation (a positively charged ion) - was thought not to exist for long because theory said it was unstable. // "I’ve said this molecule is...

MULTAQ(R) (dronedarone) for Atrial Fibrillation or Atrial Flutter Now Available in the United States

...V) or NYHA Class II - III heart failure with a recent decompensation requiring hospitalization or referral to a specialized heart failure clinic. This unstable population corresponds to the population of the ANDROMEDA trial in which patients receiving dronedarone had a greater than two-fold increase in mortal...

Daiichi Sankyo and Lilly Receive U.S. FDA Approval for Effient(TM)

...ept for patients in high-risk situations, such as those with diabetes or a history of prior heart attack. ACS, which includes heart attacks and unstable angina (chest pain), affects nearly 1.5 million people in the United States annually, many of whom are managed with PCI(i). In 2009, an estimated 785,...

Caltech chemists say antibody surrogates are just a 'click' away

..."The thing that limits us in being able to go to, say, 200 proteins in the barcode chip is that the antibodies that you use to detect the proteins are unstable and expensive," says Heath. "We have been frustrated with antibodies for a long time, so what we wanted to be able to do was develop antibody equivale...

Screen All Newborns for Hip Dysplasia, Study Urges

... arthritis, says a new study. Developmental hip dysplasia -- the most common congenital defect in newborns -- occurs when a hip joint is shallow or unstable or when the joint is dislocated. Infants with the condition can develop arthritis of the hip when they're young adults. Researchers analyzed data f...

FDA Approves Multaq(R) for Patients with Atrial Fibrillation or Atrial Flutter

...V) or NYHA Class II - III heart failure with a recent decompensation requiring hospitalization or referral to a specialized heart failure clinic. This unstable population corresponds to the population of the ANDROMEDA trial in which patients receiving dronedarone had a greater than 2-fold increase in mortalit...
Unstable in Medical Technology

Ranexa(R) Added to New ACC/AHA Guidelines on Unstable Angina/Non ST-Elevation Myocardial Infarction (UA/NSTEMI)

PALO ALTO, Calif., Aug. 15 /PRNewswire-FirstCall/ -- CV Therapeutics, Inc. (Nasdaq: CVTX ) announced today that new guidelines, developed jointly by the American College of Cardiology Foundation and the American Heart Association and published in this week's issue of Circulation, state that, ...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

...aution in patients with conditions and medical conditions that could affect metabolism or hemodynamic responses. (e.g. Recent Myocardial infarction or unstable cardiac disease) Extrapyramidal Symptoms (EPS): The overall incidence of EPS-related adverse events in patients treated with 25 mg and 50 mg of...

New Studies Show Popular Heartburn Medications Moderate the Effect of Taking Widely Prescribed Heart Drug

...iated with each of the four most popular PPIs." The adverse cardiovascular events that were measured in the study include myocardial infarction, unstable angina, transient ischemic attack/stroke, coronary revascularization or cardiovascular death. The analysis is one of a series by Medco and Indi...

Anthera's Varespladib Meets Primary Endpoint in Phase 2 FRANCIS Trial for the Treatment of Acute Coronary Syndrome

... of all-cause mortality, non-fatal stroke, non-fatal myocardial infarction, unstable angina, and a subset of revascularization following the initial event. Dur...ing at rest or upon minimal exertion. This condition is also referred to as unstable angina. If the chest pain is associated with heart muscle damage and heart ...

New Analysis Evaluated Impact of Genetic Variation on Response to Prasugrel

...ed life-threatening and fatal bleeding.(3) About Acute Coronary Syndromes Acute coronary syndromes, which is comprised of heart attacks and unstable angina (chest pain), affects nearly 1.5 million people in the United States annually.(4) Coronary heart disease, which can result in ACS, is the sing...

CRESTOR(R) Reduced CV Risk in Patients Achieving Low LDL and hsCRP Targets in New JUPITER Analysis

...tin 20mg on reducing major cardiovascular (CV) events (combined risk of myocardial infarction, stroke, arterial revascularization, hospitalization for unstable angina, or death from CV causes). JUPITER was a long-term, randomized, double-blind, placebo-controlled, large-scale study of 17,802 patients d...
Unstable in Medical Products

Hemoglobin, Unstable

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Maxxis™ 400

Description:... against risks of patient migration or inadvertent deflation of air surface. Maintain angle of articulation through hand control lock out feature for unstable cervical, thoracic and/or lumbar fractures....
Company:Kinetic Concepts, Inc.

Maxxis™ 300

Description:... against risks of patient migration or inadvertent deflation of air surface. Maintain angle of articulation through hand control lock out feature for unstable cervical, thoracic and/or lumbar fractures. ...
Company:Kinetic Concepts, Inc.

BariMaxx™ II

Description:... against risks of patient migration or inadvertent deflation of air surface. Maintain angle of articulation through hand control lock out feature for unstable cervical, thoracic and/or lumbar fractures....
Company:Kinetic Concepts, Inc.

Jerome Halo Traction Unit

Description:... Jerome Halo Traction Units provide optimum immobilization for unstable injuries of the spine. The Generation 80 superstructure is available with either 2-point (serrated disk), or 3-point (flexion/extension clip) ring adj...
Company:Jerome Medical

Biomet Low Profile Tibial Nail

Description:...on has greatly enhanced the stabilization of difficult tibial fractures. The Biomet Low Profile Tibial Nail is primarily indicated in the treatment of unstable fractures, tibial nonunion, and metastatic disease with pathologic or impending fractures but particularly useful in the treatment of very distal tibi...
Company:Biomet Orthopedics, Inc
Unstable in Medical Definition

Cryostasis (clathrate hydrates)

... [5] Clathrate hydrates are a class of solids in which gas molecules occupy "cages" made up of hydrogen-bonded water molecules. These "cages" are unstable when empty, collapsing into conventional ice crystal structure, but they are stabilised by the inclusion of the gas molecule within them. Most low mol...

High Frequency Ventilation

...s may be reduced by using smaller tidal volumes. During positive pressure ventilation, atelectatic regions will inflate, however the alveoli will be unstable and will collapse during the expiratory phase of the breath. This repeated alveolar collapse and expansion (RACE) will cause VILI. By opening the lung...
Unstable in Medical Dictionary

Vitamin B

...with ... Vitamin A. Vitamin B . Vitamin B - Complex. Vitamin C. Vitamin D ... VITAMIN B . Information and Facts ... B1 is the most unstable of the Vitamin B complex. ... High quality Vitamin B can be purchased from Global Herbal Supplies ... Niacin ( Vitamin B-3): Reference Gu...

Unstable angina

...therosclerosis of the cardiac arteries.... unstable angina is a condition in which your heart doesn't get enough blood flow ... During an unstable angina event, you may receive heparin and nitroglycerin. ... unstable angina - what is it, and how should it be treat...

Subluxation

.... In some patients, patellar subluxation can result in kneecap dislocation, a ... Also called patellar subluxation , patients who experience an unstable kneecap ... What causes a Subluxation ? ... How is a Subluxation corrected? ... These areas of abnormal movement are what chiropractors call ...

Shoulder pain

...the more common reasons for physician visits for musculoskeletal symptoms. The shoulder is the most movable joint in the body. However, it is an unstable joint because of the... Shoulder pain is an extremely common complaint that has many causes. ... When do you need to call your doctor about ...

Shoulder

... complex ... Fracture of the Shoulder Blade (Scapula) Olecranon (Elbow) Fractures. Radial Head Fractures ... A Patient's Experience with Chronic unstable Shoulder ... Your shoulder is the most flexible joint in your body. ... This flexibility also makes your shoulder susceptible to instabili...

Pedicle

... The application of pedicle screw fixation for elderly patients with degenerative ... · Percutaneous pedicle screw fixation may be effective for unstable spinal ... The number of patients with osteoporosis has increased in recent years. ... Pedicle margins are likely to be unclear in patients wi...
Unstable in Biological News

Parasites ready to jump

...A) play the central role. "Transposons are genomic parasites, so to speak", says Frstemann. "If they are allowed to proliferate, the genome can become unstable or cancers can develop. We now want to find out whether mammalian cells possess this newly discovered defence mechanism and to elucidate precisely how...

Common allergy drug reduces obesity and diabetes in mice

...ng blood flow to the site. However, in certain conditions mast cells build up to levels far beyond what the body needs. As a result these cells become unstable and eventually, like punctured trash bags, leak molecular "garbage" into the tissue. This can result in chronic inflammation that causes asthma and c...

Telomeres resemble DNA fragile sites

...vulnerable chromosome ends from molecular attack. Researchers at Rockefeller University now show that telomeres have their own weakness. They resemble unstable parts of the genome called fragile sites where DNA replication can stall and go awry. But what keeps our fragile telomeres from falling apart is a pro...

NSF provides $3.4 million to study climatically important Agulhas Current

... around to eventually flow eastward toward Australia. This retroflection is unstable and regularly sheds large Agulhas Rings, which carry Indian Ocean waters in...ied climatic impacts such as heat transport into the Southern Ocean via the unstable retroflection. The Agulhas Current Time-series (ACT) project will be con...

New nanoparticles could revolutionize therapeutic drug discovery

...ve just been published online in the Journal of the American Chemical Society , will give scientists access to previously ignored proteins deemed too unstable to work with. Professor Michael Overduin, from the University of Birmingham, who led the study, explained: "We have shown how a polymer can wrap ar...

Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease

... directly or its helpers, is a good thing." While every cell needs heat shock proteins, cancer cells need them even more to maintain their mutated, unstable and extremely busy proteins, he says. "The terminology we use is that the Hsp90 machinery is hijacked by cancer," says Dr. Chadli. Proteins that enab...
Unstable in Biological Technology

Ranexa(R) Added to New ACC/AHA Guidelines on Unstable Angina/Non ST-Elevation Myocardial Infarction (UA/NSTEMI)

PALO ALTO, Calif., Aug. 15 /PRNewswire-FirstCall/ -- CV Therapeutics, Inc. (Nasdaq: CVTX ) announced today that new guidelines, developed jointly by the American College of Cardiology Foundation and the American Heart Association and published in this week's issue of Circulation, state that, ...

Multiple Types of Heart Attacks Reduced by Prasugrel in TRITON-TIMI 38 Trial

...cluded life-threatening and fatal bleeding.(5) About Acute Coronary Syndromes Acute coronary syndromes (ACS), which includes heart attack and unstable angina (chest pain), affects more than 1.4 million people in the United States annually.(6) Coronary heart disease, which can result in ACS, is the si...

VIA Pharmaceuticals Announces Complete Enrollment in FDG-PET Phase 2 Study of VIA-2291 in Cardiovascular Patients

...ent in a Phase 2 clinical trial of its lead drug, VIA-2291 in patients who have experienced an acute coronary syndrome event such as a heart attack or unstable angina. The randomized, double blind, placebo-controlled study examines the impact of VIA-2291 on plaque inflammation as measured by Positron Emission...

European Commission Approves EFIENT(R) (prasugrel) for Patients with Acute Coronary Syndrome Undergoing PCI

...s with acute coronary syndromes who are undergoing PCI. About Acute Coronary Sy n drome Acute coronary syndrome includes heart attacks and unstable angina (chest pain). Coronary heart disease, which can result in ACS, is the single most common cause of death in the European Union, accounting for ...

Jatropha Sector Reality Check: Still Viable In Volatile Times? Upcoming Webcast Shares Latest Insights

...sustainable, clean burning biofuel, it is more important than ever that those with an interest in Jatropha curcas stay abreast of the effect today's unstable global economy has on the Jatropha sector. Dr. Mike Taverner, Executive Chairman of Jatoil Ltd., will chair the upcoming webinar. Utilizing 20 ye...

Anthera Completes Enrollment and Dosing of Varespladib Cardiovascular Trial

...of cardiovascular death, non-fatal stroke, non-fatal myocardial infarction, unstable angina, and a subset of revascularization following the initial event. Dur...ing at rest or upon minimal exertion. This condition is also referred to as unstable angina. If the chest pain is associated with heart muscle damage and heart...
Unstable in Biological Products

CopyControl cDNA, Gene and PCR Cloning Kit w/ Chemically Competent E. coli cells from EPICENTRE Biotechnologies

Description:...e of polymerase used, are efficiently cloned. All PCR products including those that are difficult to clone by other PCR cloning methods or that may be unstable or code for potentially detrimental proteins can be cloned and maintained as single copy to ensure their stability. Once the clones are identified, th...
Company:EPICENTRE Biotechnologies

CORNING CELLBIND CULTURE FLASK, 25CM2, CANTED NECK, VENT CAP, STERILE from Sigma-Aldrich

Description:...th uunder difficult conditions, including reduced serum or serum-free medium. • CellBIND may provide a more ecominic alternative to expensive and unstable biological coatings. • Both enzymatic and non-enzymatic dissociating solutions have been used to remove and harvest cells from CellBIND surfaces,...
Company:Sigma-Aldrich

CORNING CELLBIND CULTURE FLASK, 175CM2, ANGLED NECK, VENT CAP, STERILE from Sigma-Aldrich

Description:...th uunder difficult conditions, including reduced serum or serum-free medium. • CellBIND may provide a more ecominic alternative to expensive and unstable biological coatings. • Both enzymatic and non-enzymatic dissociating solutions have been used to remove and harvest cells from CellBIND surfaces,...
Company:Sigma-Aldrich

CORNING CELLBIND CULTURE FLASK, 175CM2, ANGLED NECK, PHENOLIC-STYLE CAP, STERILE from Sigma-Aldrich

Description:...th uunder difficult conditions, including reduced serum or serum-free medium. • CellBIND may provide a more ecominic alternative to expensive and unstable biological coatings. • Both enzymatic and non-enzymatic dissociating solutions have been used to remove and harvest cells from CellBIND surfaces,...
Company:Sigma-Aldrich

MMP-2 Inhibitor I from Calbiochem

Description:...DER INERT GAS. A potent inhibitor of MMP-2 that acts in a dose-dependent manner (K i = 1.7 μM). Purity: ≥98% by TLC. Soluble in EtOH or DMSO. unstable in solution, reconstitute just prior to use. M.W. 297.5. ...
Company:Calbiochem
Unstable in Biological Definition

Antibiotic

...pyocyaneus, retarded the growth of other bacteria in situ and was toxic to many disease-causing bacteria. Unfortunately, pyocyanase's own toxicity and unstable character prevented its use as an effective, safe antibiotic within the human body. The first effective antibiotic discovered was penicillin . Fren...
Unstable in Biological Dictionary

Triplet repeat expansion

...on ... The triplet repeat expansion is sometimes called a dynamic or unstable mutation ... Disease. 1.2 Expansion of Triplet Repeats ... Lesson ... 3) ... The triplet repeat expansion is sometimes called a dynamic or unstable mutation ... Sureshkumar S. A Genetic Defect Caused by a Triplet Re...

Klenow Fragment

...d ... Klenow fragment Treatment of the enzyme DNA polymerase 1 with subtilism produces two cleavage products, a small fragment which is unstable and a large 3' polymerase activity of Klenow Fragment can be used in the following applica ... Klenow Fragment is also active in many re...
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Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2Two-faced gene: SIRT6 prevents some cancers but promotes sun-induced skin cancer 2Building a bridge from basic botany to applied agriculture 2Building a bridge from basic botany to applied agriculture 3
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