Understanding

UCSB scientists probe sea floor venting to gain understanding of early life on Earth

New keys to understanding the evolution of life on Earth may be found in the microbes and minerals vented from below the ocean floor, say scientists at the University of California, Santa Barbara. The UCSB scientists are making new contributions to this field of inquiry in their studies of seafloor hydrothermal fluid discharge into the Earth's oceans, which has been occurring ever since t...

Zebrafish may hold key to understanding human nerve cell development

Glia appear essential for 'hair cells'responsible for hearing and balance. Traditionally viewed as supportingactors, cells known as glia may be essential for the normal developmentof nerve cells responsible for hearing and balance, according to newUniversity of Utah research. The study is reported in the January 6,2005 issue of Neuron and is co-authored by scientists at the Universityof Was...

Novel ultrafast laser detection of cancer cells also may improve understanding of stem cells

To investigate tumors, pathologists currently rely on labor-intensive microscopic examination, using century-old cell-staining methods that can take days to complete and may give false readings. A lightning-fast laser technique, led by Sandia National Laboratories researcher Paul Gourley, has provided laboratory demonstrations of accurate, real-time, high-throughput identification of live...

Researchers make gains in understanding antibiotic resistance

Howard Hughes Medical Institute researchers chiseling away at the problem of antibiotic resistance now have a detailed explanation of how the drugs' main cellular target in bacteria evolves to become resistant to some of these medications. The findings are already leading to new experimental antibiotics that are being engineered to circumvent resistance, which is a major worldwide health problem....

Brain-mapping technique aids understanding of sleep, wakefulness

The power of a new technique to map connections among nerve cells in the brain has a UT Southwestern Medical Center scientist dreaming of solving the mysteries of sleep. By tracking which nerve cells in the mouse brain stimulate others, researchers in Japan and at UT Southwestern found that a type of neuron responsible for keeping animals awake receives inhibitory signals from neurons act...

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A Further Step in Understanding Apoptosis Direct Detection of PARP Cleavage

Detection of early apoptotic events has become quiterelevant since many studies have demonstrated thatabnormalities in cell death regulation cause a variety ofdiseases and pathological conditions accompaniedeither by cell accumulation (e.g., cancer) or by cell loss(e...

Understanding at Medicine News

Understanding The Predictors Of Prostate Cancer

A new study could change the way doctors treat certain prostate cancer patients.The three strongest predictors for the outcome for a prostate cancer patient are grade, PSA level and pathologic stage. //The summation of these three predictors is what determines the Gleason grading system or a Gleason score (GS). The most common Gleason score among patients with prostate cancer is seven. In a new s...

Understanding Restless Legs Syndrome

Restless legs syndrome is an irritating feeling of uneasiness, tiredness and itching deep in the muscles of the legs. The symptoms can be painful // and often worsen at night. A new study aims to better understand the common condition called restless legs syndrome. Studies on restless legs syndrome are rare. However, researchers in Germany recently conducted a population-based study to l...

Understanding Lung Cancer Metastasis

Around 165,000 cases of lung cancer are diagnosed in the United States annually, and of these, 20 percent to 25 percent are classified // as small cell lung carcinoma (SCLC). Prognosis for these patients is poor, and the disease frequently travels to the brain and central nervous system. The probability of developing brain cancer, for example, ranges up to 80 percent. Whether or not thes...

Understanding The Link Between Hormone Replacement and Respiratory Disease

Taking hormones after menopause could put a woman at increased risk of developing asthma, report researchers // ,however hormone replacement doesn’t appear to affect chronic obstructive pulmonary disease (COPD) risk. The incidence of both asthma and COPD are rising in the developed world. About 5 percent to 8 percent of Americans have asthma, and deaths due to COPD have risen more than 4...

Understanding The Risks Of Hormone Therapy

Women who take hormone therapy that combines estrogen with progestin have double the risk for venous thrombosis ( VT ), a type of blood clot,// according to a recent study. VT affects one to two people in every 1,000. Risk for VT increases with age and is higher in men, blacks and obese individuals. Postmenopausal hormone therapy is associated with a two- to three-fold increased risk of...

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Othera Pharmaceuticals Announces Upcoming Presentation Based Upon Expanded Understanding of Lead Compound Mechanism of Action

EXTON, Pa.--(BUSINESS WIRE)--Apr 19, 2007 - Othera Pharmaceuticals,Inc. today announced that Dr. Shaker Mousa, Professor ofPharmacology and Executive Vice President and Chairman of thePharmaceutical Research Institute at Albany College of Pharmacy,will present new preclinical data detailing the observedantithrombotic effect of Othera's lead compound, OT-551, andrelated Othera compounds. Thi...

Use of Sequenom's MassARRAY System Leads to Significant Scientific Advances in Understanding Cancer, Diabetes and Drug-Resistant Malaria

SAN DIEGO--(BUSINESS WIRE)--Mar 14, 2007 - Sequenom, Inc. (NASDAQ:SQNM) today announced that its MassARRAY(R) technology andiPLEX(TM) assay were used by leading scientists from internationalresearch institutions and, in independent studies, significantlyadvanced the understanding of cancer, diabetes and drug-resistantmalaria. Results from several of these studies were published inhighly rec...