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Crestor Patent Invalidity Evidence Uncovered By Article One Partners Community

AstraZeneca Patent Shown to be Invalid Based on New Prior Art; JSA Technologies Patent Study Yields Strong Invalidity Evidence NEW YORK, July 1 /PRNewswire/ -- Article One Partners, LLC has discovered new prior art impacting the validity of AstraZeneca's Crestor U.S. drug patent, in closing ...

Health Secrets of Red Wine Uncovered

But for maximum benefits, sip don't gulp, research shows THURSDAY, June 11 (HealthDay News) -- Scientists already knew that drinking red wine in moderation is good for your health; now they are figuring out why. New research is uncovering the disease-prevention secrets of a polyphen...

Genetic link uncovered in disparate colon cancer death

BIRMINGHAM, Ala. A new study reveals the first-ever genetic link to the reason African-Americans are at increased risk of dying from colon cancer. The discovery by researchers at the University of Alabama at Birmingham (UAB) is focused on a protein variant called Pro72 identified through genet...

'Relocation' plan of metastatic cancer cells uncovered by Stanford researchers

STANFORD, Calif. Few things are as tiresome as house hunting and moving. Unfortunately, metastatic cancer cells have the relocation process down pat. Tripping nimbly from one abode to another, these migrating cancer cells often prove far more deadly than the original tumor. Although little has be...

Landmark 'Pediatric Allergies in America' Survey Uncovered Negative Impact of Allergy Symptoms on Children

- Children with Allergies Less Productive Than Peers, Parents Reported - PHILADELPHIA, March 17 /PRNewswire/ -- Data from the largest survey of its kind suggested there's a silent epidemic among our nation's children. U.S. children are suffering with allergies and not getting the treatment the...

Link Between Chronic Pain and Insomnia Uncovered at PAINWeek 2007

Ninety-six Percent of Pain Care Professionals Polled during PAINWeek 2007 Said Most Patients with Chronic Pain Also Suffer from Insomnia LAS VEGAS, Sept. 8 /PRNewswire/ -- In addition to reporting a link between pain and insomnia, the polled health care professionals surveyed during PAINWee...

Link Uncovered Between Benign Prostatic Hyperplasia and NSAIDs, Says Harvard Men's Health Watch

BOSTON, Sept. 5 /PRNewswire-USNewswire/ -- Men with slow urine flow from enlargement of the prostate gland (known as benign prostatic hyperplasia or BPH) should avoid anything that makes the situation worse--and that includes some medications. The most common offenders are over-the-counter col...

Possible Viral Links to Lung Cancer Risk Uncovered

Two studies find connection between measles, HPV and most common lung cancer FRIDAY, April 25 (HealthDay News) -- Although smoking is well-established as an independent risk factor for lung cancer, two new studies suggest that two different viral infections might boost a smoker's alrea...

Elusive Step In DNA Mutation Uncovered By Researchers

Researchers have uncovered important information about how water reacts with the guanine of the ionized DNA, a critical step in DNA mutation that has eluded researchers for decades. //In the study that appears in the August edition of the Journal of the American Chemical Society, scientists at the...

New Diagnostic Tool Uncovered Gene Expression Patterns in Recessive Genetic Disorders

A new diagnostic method has been discovered by two scientists Vivian Cheung and Warren Ewens from the University of Pennsylvania to study //medical disorders that are recessively inherited. Gene expression patterns in carriers of genetic diseases would differ significantly and this new diagnost...

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uncovered in Medical Technology

Congressional 'Sting' Operation Uncovered By Coast IRB

WASHINGTON, March 12 /PRNewswire/ -- The following is being issued by Coast IRB: In a press release issued on March 10, 2009, Coast IRB informed the public that it had discovered what appeared to be a fraudulent clinical trial submitted to that Independent review board for evaluation. Coast IR...

More Gene Mutations Linked to Autism Risk

...en with ASDs from the AGRE cohort against genetic samples of 1,070 disease-free children from The Children's Hospital of Philadelphia. This study also uncovered two novel genes in which variations were found, BZRAP1 and MDGA2 - thought to be important in synaptic function and neurological development, resp...

Genetic Source of Rare Childhood Cancer Found; Gene is Implicated in Other Cancers

... cause of an inherited form of a rare, aggressive childhood lung cancer has uncovered important information about how the cancer develops and potentially sheds l...in Minnesota. "We are thrilled that our colleagues Drs. Hill and Goodfellow uncovered an important mutation and have begun to understand the cellular mix-up whic...

Research Teams at J. Craig Venter Institute and Ludwig Institute for Cancer Research Uncover New Chromosomal Alterations in Cancer Using Transcriptome Sequencing Approach

...e Ludwig Institute for Cancer Research (LICR) have uncovered new genomic alterations that lead to gene fusions ...equencing. Previous studies on this cell line have uncovered certain types of genetic mutations and chromosomal...A sequences. After extensive data mining, the team uncovered 496 sequences that indicate chromosomal translocat...

Roskamp Institute Identifies New Class of Drugs to Treat Alzheimer's Disease

...nflammation & Alzheimer's Disease SARASOTA, Fla., Dec. 16 /PRNewswire/ -- The Roskamp Institute today announced that its researchers have uncovered a new link between inflammation and Alzheimer's disease and have identified a potential target for developing novel therapeutics for intervention in t...

Nature Publication Reports on Key Role of Bile Acids in Glucose Metabolism and Insulin Signaling

...d are insulin-resistant. Dr. Schoonjans, Ph.D., a group leader at the Ecole Polytechnique Federale de Lausanne commented, "Our research efforts have uncovered a number of endocrine effects mediated by bile acids acting on receptors such as FXR and TGR5. This review is one of the first to provide a comprehens...

Research Explains How Advanced Prostate Cancer Becomes Resistant to Androgen-Deprivation Therapy

...nge, M.D., of the University of Washington School of Medicine, in collaboration with other colleagues at UW and Oregon Health Sciences University, has uncovered what may be the key to understanding how prostate tumors eventually become resistant to androgen-deprivation therapy. "We found that despite the sup...

Steps Toward Stopping Autoimmune Disease: International Consortium Identifies Genes Linked to Lupus

...variants that might predispose an individual to developing lupus. Published in the January 20, 2008, issue of Nature Genetics, initial study results uncovered several genes linked to lupus and underscore the importance of genetic variants in diseases that affect immune function. The findings will ultimately ...

Groundbreaking Study Proves Personalized Diet Based on Genetics Leads to Significant Advances in Long Term Weight Management and Blood Glucose Levels

...tic profile, has created a powerful set of tools utilizing their proprietary Rules Engine which allows consumers to harness the scientific information uncovered in the landmark Human Genome Project. For more information, visit Sciona, Inc. at http://www.Sciona.com, or the Mycellf product website at http://w...

454 Sequencing(TM) in Science Today: Researchers Uncover a Genetic Basis for Different Social Behaviors in Wasps

...4 Life Sciences, a Roche company, in collaboration with researchers from the University of Illinois at Urbana-Champaign today announced that they have uncovered genetic underpinnings to social behavior in wasps. Using the company's Genome Sequencer(TM) system, the researchers examined messenger RNA from the br...
uncovered in Biological News

New indicator uncovered that can predict coral health

Honolulu, HI A new indicator of coral health has been discovered in a community of microscopic single-celled algae called dinoflagellates. The study, released in the July 8th edition of the journal Proceedings of the National Academy of Sciences, reveals that a particular type of these algae re...

Poxvirus potency uncovered in new atomic map

BIRMINGHAM, Ala. Scientists at the University of Alabama at Birmingham (UAB) and Saint Louis University used X-ray crystallography to uncover new details about the infectious potency of poxviruses, furthering the understanding of how one protein in viral infections can subvert the bodys immune sy...

America's smallest dinosaur uncovered

An unusual breed of dinosaur that was the size of a chicken, ran on two legs and scoured the ancient forest floor for termites is the smallest dinosaur species found in North America, according to a University of Calgary researcher who analyzed bones found during the excavation of an ancient bone ...

Cancer signatures uncovered

A new systematic analysis of the relationship between the neoplastic and developmental transcriptome provides an outline of trends in cancer gene expression. The research, published recently in BioMed Central's open access journal Genome Biology, describes how cancers can be divided into three gro...

Anthrax cellular entry point uncovered

BIRMINGHAM, Ala. The long-sought-after biological gateway that anthrax uses to enter healthy cells has been uncovered by microbiologists at the University of Alabama at Birmingham (UAB). Anthrax spores enter the cell through something called Mac-1, a receptor that sits on the surface of certai...

Hemoglobin uncovered

The transport of oxygen in blood is undertaken by hemoglobin, the largest component of red blood cells. This protein collects oxygen in respiratory organs, mainly in the lungs, and releases it in tissues in order to generate the energy necessary for cell survival. Hemoglobin is one of the most ref...

Agent that triggers immune response in plants is uncovered

Although plants lack humans' T cells and other immune-function cells to signal and fight infection, scientists have known for more than 100 years that plants still somehow signal that they have been attacked in order to trigger a plantwide resistance. Now, researchers at the Boyce Thompson Institu...

The hepatitis healing power of blueberry leaves

...low or stop disease progression. So they screened nearly 300 different agricultural products for potential compounds that suppress HCV replication and uncovered a strong candidate in the leaves of rabbit-eye blueberry (native to the southeastern US). They purified the compound and identified it as proanthoc...

Parasites ready to jump

... the Gene Center of Ludwig-Maximilians-Universitt (LMU) in Munich and a team of researchers working with the fruitfly Drosophila melanogaster have now uncovered a new type of cellular defence that acts against DNA sequences present in high copy numbers inside the cell, even if they have not integrated into the...

A crystal ball for brain cancer?

... UCLA researchers have uncovered a new way to scan brain tumors and predict which ones will be shrunk by the...d medication costing up to $10,000 per month. Now UCLA scientists have uncovered a new way to image tumors and forecast which patients, like McNabb, are mos...
uncovered in Biological Technology

Cancer-Related miRNAs Uncovered by the mirVana miRNA Microarray Platform

Ambion has developed a complete line of research tools for the analysis of microRNAs (miRNAs). Recently, we introduced the mir Vana miRNA microarray platform (consisting of the mir Vana miRNA Labeling Kit and the mir Vana miRNA Probe Set...

New drugs faster from natural compounds: A UC San Diego breakthrough

...lic NRP discussed in the Nature Methods paper that was thought to be novel when it was isolated. A lengthy and expensive patenting process, however, uncovered that compound 879 had already been described as an antibiotic and named neoviridogrisen. The new UC San Diego algorithms would have quickly identified...

Scientists discover repulsive side to light force

...ould be manipulated to move components in semiconducting micro- and nano-electrical systemstiny mechanical switches on a chip. The scientists have now uncovered a complementary repulsive force. Researchers had theorized the existence of both the attractive and repulsive forces since 2005, but the latter had re...

Unexpectedly long-range effects in advanced magnetic devices

...urprised them. As expected, the ferromagnetic material directly under the grid lines showed the pinning effect, but, quite unexpectedly, so did the uncovered material in regions between the grid lines far removed from the antiferromagnetic material. "This pinning effect extends for maybe tens of nanometers ...

Researchers solve 'bloodcurdling' mystery

... CAMBRIDGE, Mass., June 4, 2009 By applying cutting-edge techniques in single-molecule manipulation, researchers at Harvard University have uncovered a fundamental feedback mechanism that the body uses to regulate the clotting of blood. The finding, which could lead to a new physical, quantitative, ...

Michael J. Fox Foundation Commits Up To $5 Million for Pre-Clinical Drug Development Under Industry-Exclusive Therapeutics Development Initiative

...a more attractive bet and help to push research further along the pipeline. Years of basic research in cell-based studies and animal models have uncovered numerous promising biological targets that show initial promise to impact the symptoms and progression of Parkinson's disease. But translating these f...

New uses for imidazolium salts in medicine and alternative energy

... Scientists at Singapore's Institute of Bioengineering and Nanotechnology (IBN) have uncovered new properties of imidazolium salts (IMSs), which suggest that they could play a vital role in disease prevention and treatment. The report on the...

Stretching silicon: A new method to measure how strain affects semiconductors

...he researchers have determined the direction and magnitude of shifts in the conduction bands. Their findings have shed light on divergent theories and uncovered some surprising properties. Understanding these properties, and the energy shifts in strained materials, could lead to the improvement of fast, flexib...

Large-scale genetic study sheds new light on lung cancer

...lete set of DNA, or genome, found in various types of cancer. "We found lung adenocarcinoma to be very diverse from a genetic standpoint. Our work uncovered many new targets for therapy of this deadly disease -- oncogenes that drive particular forms of lung adenocarcinoma and tumor suppressor genes that wo...

New stem cell tools to aid drug development

...TRA." Dr Whiting said: "We've set out to make stable mimics of natural compounds which control cell development, but in this case, not only have we uncovered a compound which is not only stable and does what the natural system does, but it actually seems to be better as well. It's a real bonus and shows the...
uncovered in Biological Definition

Endosymbiont

... healthier when their plant sap diet is supplemented with the appropriate amino acids , and (2) after the Buchnera genome was sequenced, analysis uncovered a large number of genes that likely code for amino acid biosynthesis genes; most bacteria that live inside other organisms do not have such genes, so ...

Endosymbiont

... healthier when their plant sap diet is supplemented with the appropriate amino acids , and (2) after the Buchnera genome was sequenced, analysis uncovered a large number of genes that likely code for amino acid biosynthesis genes; most bacteria that live inside other organisms do not have such genes, so ...

Systems biology

...onsider or develop hypotheses that aim to describe the system. Inconsistencies or gaps between such hypotheses and the supporting data may be rapidly uncovered and resolved. Data-driven ...
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