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Unchecked in Medical News

Obama: 'Too Many Still Die from Diseases That Shouldn't Kill Them...'

...t by our conscience and our common interest. When a child dies of a preventable illness in Accra, that diminishes us everywhere. And when disease goes unchecked in any corner of the world, we know that it can spread across oceans and continents." Obama told the audience that his administration has com...

Actuaries: Addressing Health Spending Growth is Path to Sustainable Health Care System

...o grow at this pace, health insurance premiums will continue to increase as well. Thus efforts to rein in health insurance premiums will be negated if unchecked rising health spending drives premiums to their original levels within a few years and even higher thereafter. Uccello also said that mounting ev...

Swine Flu: A Spread Southward Could Be Disaster for Weak Public Health Systems

...th director for World Vision International. "Still, it is where health systems and structures are inadequate that the disease is most likely to spread unchecked and take its greatest toll on lives." "This swine flu, like avian influenza outbreaks before it, highlights a critical weakness in the way the ...

Major Stakeholders in Health Reform Debate Call for Improvements in Scoring of Congressional Health Care Proposals

...at, once corrected, would more accurately recognize the value of health care efforts aimed at attacking a significant driver of health care costs: the unchecked growth in common and costly chronic diseases, and related problems such as obesity. In a letter to House Speaker Nancy Pelosi and Senate Majority...

How cells change gears: New insights published in Nature Genetics

... if you found a compound that inhibits this gene, you could make the cells begin to differentiate towards a normal monoblast line rather than continue unchecked cell proliferation," said Ravasi. Resilient and Redundant Based on the new research, it appears that the network of transcription factors fro...

Calif. Nurses to Gather for First Major Hearing on Bill to Establish Guaranteed Healthcare for All Californians

...of patients are skipping critical mammography screenings, dental visits, care for chronic health conditions, and other preventive needs because of the unchecked costs of insurance premiums, deductibles, co-pays and other out-of-pocket costs. "SB 810 is the only healthcare reform in California that protect...

Southern California Parents and Kids Take Healthy Steps in Tackling Childhood Obesity

... KID HEALTHY -- Steps to Healthy Living. "But the truth is we're far from reversing the trends. As these children age into adulthood, if obesity goes unchecked they will experience chronic illness and death at a much earlier age than their parents. And that's a real tragedy, especially when we have an opport...

Protein helps immune cells to divide and conquer

...sh the cell forward to divide. "Since B cells can't rapidly divide and replicate without CD98hc, perhaps by blocking this protein we could stop the unchecked growth of B lymphocyte cells that can result in cancer or block misdirected B cell attacks that can cause certain autoimmune diseases," said Ginsberg....

Health System Collapse Requires International Intervention, Concludes PHR Report

... the widely reported cholera epidemic, the report highlights increases in maternal mortality, growing malnutrition, disruptions in HIV/AIDS treatment, unchecked tuberculosis, and outbreaks of anthrax. This report highlights related human rights violations and explains why the Mugabe regime must be held account...

Hodgkin lymphoma -- new characteristics discovered

...s. IL-21 activates a specific signaling pathway (STAT3), thus up-regulating the expression of a group of specific genes in HRS cells which support the unchecked growth and survival of HRS cells. IL-21 also activates a chemoattractant for cells which suppress the immune system On top of that, accordi...
Unchecked in Medical Technology

EpiCept Announces Successful Completion of Enrollment for Phase I Trial of EPC2407

...ics, Inc. as part of an exclusive, worldwide development and commercialization agreement. About EpiCept's ASAP Technology Cancer cells often exhibit unchecked growth caused by the disabling or absence of the natural process of programmed cell death, which is called apoptosis. Apoptosis is normally triggered ...

EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound

...und's Phase II trials as the clinical profile from the ongoing monotherapy trial emerges. About EpiCept's ASAP Technology Cancer cells often exhibit unchecked growth caused by the disabling or absence of the natural process of programmed cell death, which is called apoptosis. Apoptosis is normally triggered ...

Mode of Action of EpiCept-Licensed Cancer Compound Profiled at AACR

...ts with primary brain cancer and the other in melanoma that has spread to the brain. About EpiCept's ASAP Technology Cancerous cells often exhibit unchecked growth caused by the disabling or absence of the natural process of programmed cell death, which is called apoptosis. Apoptosis is normally triggered ...

New Research Demonstrates Broad Efficacy of Azixa (MPC-6827) Against Multiple Tumor Types and in Drug Resistant Cell Lines

...nd Oncology and Department of Internal Medicine, Innsbruck Medical University, Austria. About EpiCept's ASAP Technology Cancer cells often exhibit unchecked growth caused by the disabling or absence of the natural process of programmed cell death, which is called apoptosis. Apoptosis is normally triggered ...
Unchecked in Medical Dictionary

Metabolic acidosis

... In medicine, metabolic acidosis is a process which if unchecked leads to acidemia, i.e. blood pH is low due to increased production of H+ by the body or the inability of the body to form bicarbonate (HCO3-) in th...

Acidosis

...ed acidity . If not further qualified, it usually refers to acidity of the blood plasma. In medicine, metabolic acidosis is a process which if unchecked leads to acidemia, i.e. blood pH is low due to increased production of H+ by the body or the inability of the body to form bicarbonate (HCO3-) in th...
Unchecked in Biological News

Tumor suppressor gene in flies may provide insights for human brain tumors

...e PP2A usually have the opposite biochemical function to kinase, the scientists predicted that PP2A would stop the tumor suppressor Polo and allow for unchecked cell growth. "We were very surprised when we found that PP2A also suppressed tumors," Wang said. Follow-up experiments showed that PP2A is importa...

CSHL-led team identifies key decision-point at which cells with broken DNA repair themselves or die

...cells orchestrate a response to signals from such resident sensors when they are triggered by exposure to radiation or other toxic processes, which if unchecked can cause genes to mutate and cancerous tumors to begin forming. A team of biologists led by Professor Nicholas Tonks, Ph.D., F.R.S., of Cold Spr...

New discovery may lead to new class of allergy drugs

...role of eotaxin should provide novel therapeutic opportunities for intervention during diseases like asthma, food allergies and other situations where unchecked allergic responses cause problems." According to the U.S. Centers for Disease Control and Prevention Allergies, more than 50 million Americans suff...

Dramatic expansion of dead zones in the oceans

... unchecked global warming would leave ocean dwellers gasping for breath. Dead zones ar... fertilizers from farming. A team of Danish researchers have now shown that unchecked global warming would lead to a dramatic expansion of low-oxygen areas zones...

Smithsonian puts tropical eastern Pacific shore fishes online

...e records. Robertson checks all location reports and deletes likely wild cards, creating a much more accurate reference than global databases based on unchecked published reports. He works closely with other researchers and with fishermen who send photos of unusual catches, some of which result in new points o...

Smithsonian puts tropical Eastern-Pacific shore fishes online

...e records. Robertson checks all location reports and deletes likely wild cards, creating a much more accurate reference than global databases based on unchecked published reports. He works closely with other researchers and with fishermen who send photos of unusual catches, some of which result in new points o...

Researchers identify Achilles heel of common childhood tumor

...d that at least two gene mutations were capable of setting off a chain of events that ultimately stymied those receptors. That allowed VEGF to trigger unchecked growth in the endothelial cells. These findings open up new treatment options, according to study leader Bjorn R. Olsen, the Hersey Professor of ...

Food for thought -- regulating energy supply to the brain during fasting

... LA JOLLA, CAIf the current financial climate has taught us anything, it's that a system where over-borrowing goes unchecked eventually ends in disaster. It turns out this rule applies as much to our bodies as it does to economics. Instead of cash, our body deals in energy b...

Scientists identify novel inhibitor of human microRNA

...nds that selectively repress miRNA. They selected miR-21 as the target agent due to its documented role in preventing cell death thereby allowing the unchecked cell proliferation associated with cancer and its elevated levels in various cancers. The team designed an assay that contained the DNA binding se...

New insights into the regulation of PTEN tumor suppression function

...es, serves to direct PTEN out of the nucleus. "We discovered that this pathway is disrupted through the loss or mutation of PML, as well as through unchecked HAUSP expression, either of which can force PTEN from the nucleus and prevent its ability to act as a tumor suppressor," notes Pandolfi. "The modula...
Unchecked in Biological Technology

Large-scale genetic study sheds new light on lung cancer

... Neurofibromatosis 1 (NF1). Mutations in this gene have previously been shown to cause neurofibromatosis 1, a rare inherited disorder characterized by unchecked growth of tissue of the nervous system. Ataxia Telengiectasia Mutated (ATM). ATM mutations have previously been shown to play a role in ataxia te...

Thousands Rally in Mexico City and Call for Human Rights Protections in Global AIDS Response

... programs, yet they continue to face discrimination and abuse and are often denied access to lifesaving programs. As a result, HIV continues to spread unchecked in communities worldwide. "Stigma and discrimination are more devastating than AIDS, and its cost is much higher because it strains social relations...

EpiCept to Present Pre-clinical Advances of Myc Oncogene Directed Drug Discovery at Assays and Cellular Targets Conference

...rrently in clinical development, EPC2407 in Phase I and Azixa(TM)* in Phase II trials. About EpiCept's ASAP Technology Cancerous cells often exhibit unchecked growth caused by the disabling or absence of the natural process of programmed cell death, which is called apoptosis. Apoptosis is normally triggered ...

CDC Awards NATT Funding to Improve Blood Clot Awareness

...lia (NATT) today announced the award of two major program grants totaling $1.35 million that will serve as building blocks for its efforts to curb the unchecked devastating effects caused each year to nearly one million Americans who develop a blood clot. NATT will use its two Centers for Disease Control and ...

EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound

...und's Phase II trials as the clinical profile from the ongoing monotherapy trial emerges. About EpiCept's ASAP Technology Cancer cells often exhibit unchecked growth caused by the disabling or absence of the natural process of programmed cell death, which is called apoptosis. Apoptosis is normally triggered ...

Wireless carriers mislead consumers about USF reform

...eness. The march of telecommunications progress, however, is not without obstacles. Wireless phone providers have added complexity to the Fund. The unchecked expansion of USF support to predominantly wireless telephone companies has driven up the funding allocated through USF by 1,000 percent, threatening u...

Caspase-3 Activation - An Indicator of Apoptosis in Image-Based Assays

...elieved to lead to premature apoptosis in the affected tissue. At the same time, damaged cells that do not enter the apoptotic pathway may proliferate unchecked and become a cancerous cell mass. Thus, the study of apoptosis benefits many different fields of medicine by offering multiple targets for specific dr...
Unchecked in Biological Definition

Diabetes mellitus

... test strip for an older style (ie, optical color sensing) monitoring system Prolonged and elevated levels of glucose in the blood, which is left unchecked and untreated will, over time, result in serious diabetic complications and sometimes even death. It is therefore highly important that a diabetic pat...

Population

...ation which it can support. Some observers of human societies believe that the concept of carrying capacity also applies to human population, and that unchecked population growth can result in a " Malthusian catastrophe ". Others dispute this view. Population may also mean the process of populating a ...

Thomas Malthus

...thus predicted population would outrun food supply, leading to a decrease in food per person. This prediction was based on the idea that population if unchecked increases at a geometric rate (i.e. 2, 4, 8, 16, 32, 64, 128, etc.) whereas the food supply grows at an arithmetic rate (i.e. 1, 2, 3, 4, 5, 6, 7, e...
Unchecked in Biological Dictionary

Cell growth

...nism by which p53 regulates cells and ... Abnormal cell proliferation and growth are characteristics of cancer. ... In Yamagiwa's case it was unchecked cancer cell growth . ... If the cell remains in an active growth cycle, it then embarks on the "S" stage ... breast cancer cell growt...
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