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Unchanged in Medical News

ARDS mortality is unchanged since 1994

Mortality in patients with acute respiratory distress syndrome (ARDS) has not fallen since 1994, according to a comprehensive review of major studies that assessed ARDS deaths. This disappointing finding contradicts the common wisdom that ARDS mortality has been in steady decline. The study was...

Hill-Rom Reports Second Quarter Revenue Growth of 12.0 Percent to $375.2 Million and Adjusted Earnings Per Fully Diluted Share from Continuing Operations of $0.26, Unchanged from the Prior Year

- Both capital sales and rental revenue increase 12.0 percent demonstrating balanced growth - Hill-Rom reporting for first time since separation; strategic investments showing results - Management updates financial guidance based on year to da...

Breast Cancer Unchanged in Black Women, Despite Drop in HRT Use

More estrogen-receptor negative tumors may be a factor, experts suggest,,,, TUESDAY, April 15 (HealthDay News) -- Although the overall incidence of breast cancer dropped dramatically after millions of American women stopped using hormone-replacement therapy in 2002, that decline doesn'...

CPR Survival Rates for Older People Unchanged

Lack of improvement in death rates, experts say, may be because recipients are sicker,,,, WEDNESDAY, July 1 (HealthDay News) -- Despite efforts to fine-tune the procedure for cardiopulmonary resuscitation, or CPR, the survival rate for older people given CPR has not changed much in re...

Rheumatoid Arthritis Death Rate Unchanged

Underlying inflammation may affect heart despite symptom relief, experts say MONDAY, Oct. 29 (HealthDay News) -- Americans are likely to live longer than they did 40 years ago, but not if they have rheumatoid arthritis, according to a new study from the Mayo Clinic. "When you look ...

Diabetic Death Rate Drops in Men but Remains Unchanged for Women

The death rate among US diabetics between 1971-2000 fell significantly for men, but remained unchanged for women, said a medical study Tuesday that did not seek the cause of the gender disparity . The Epidemiology and Statistics Branch of the Division of Diabetes Translation at the Centers...

West Announces Second Quarter 2009 Results

...and acquisition-related legal services. Research spending was substantially unchanged from the prior-year quarter. Resulting operating profit was $34.2 million,...combined $0.4 million higher. Net interest expense was substantially unchanged from the prior-year period. The Company's reported tax expense reflects an ...

STAAR Surgical Generates Cash From Operations During Second Quarter

...rgin products. Sales of these lower margin products declined by 23.5% or $1.5 million during the second quarter. Gross profit margin was 55.8%, unchanged from the second quarter of 2008. Operating expenses declined by 16% to $11.3 million from $13.5 million reported for the second quarter of 2008....

BioMarin Announces Second Quarter 2009 Financial Results

... $160 to $175 Kuvan Net Product Revenue unchanged $70 to $80 Aldurazyme Net Product Revenue to BioMarin unchanged $69 to $74 Selected Income S...st of Sales (% of Total Revenue) unchanged 19% to 21% Selling, General ...

STERIS Corporation Announces Fiscal 2010 First Quarter Results

...e of business on August 20, 2009. O utlook Based upon first quarter results and current anticipated trends, the Company's expectations are unchanged for the full fiscal year, with revenues flat to down mid-single digits and earnings per diluted share of $1.80 to $2.00. This outlook assumes the ave...
Unchanged in Medical Technology

Resveratrol Longevity Science Makes Dramatic U-Turn, But Resveratrol Supplements Remain Unchanged

Mega-dose Resveratrol, Sirtuin1 gene Target Discredited; Lower Dose, Array of Small Molecules (Longevinex(R)) Exert Greater Effect SAN DIMAS, Calif., Sept. 10 /PRNewswire/ -- While the red wine molecule resveratrol (rez-vair-ah-trawl) has recently attracted scientific and public attentio...

Results From Trials of DHA in Alzheimer's Disease and Age-Related Cognitive Decline

...rom baseline of -3.2 vs. -1 BPM, p<0.03) that was highly correlated with week 24 plasma levels (p<0.01). Blood pressure and body weight remained unchanged between groups. Plasma levels of Alzheimer's related proteins Abeta 1-40, 1-42 and hs-CRP were not significantly different. The researchers o...

Spherix Announces Positive Phase 2 Study Results

...hs of the trial. Naturlose also decreased serum LDL by an average -13 mg/dl by the end of the first month on therapy, while serum HDL was essentially unchanged (+0.9 mg/dl). The LDL:HDL ratio was improved for two of the three dose groups by an average of 0.3. "The results of this ongoing Phase 2 study ar...

New Study Evaluating the ADHD Medication VYVANSE(R) (lisdexamfetamine dimesylate) CII Demonstrated No Change in the Pharmacokinetic Profile of VYVANSE When Coadministered with Prilosec OTC(R) 40 mg (20 mg X 2), a Commonly Used Proton Pump Inhibitor (PPI)

...al to one hour. When VYVANSE was administered alone, the median time to maximum plasma d -amphetamine concentration was three hours. This remained unchanged when VYVANSE was coadministered with Prilosec OTC. Approximately 25 percent of subjects who received VYVANSE with Prilosec OTC had a shortened time t...

New Studies on Once-Daily Extended Release Pramipexole Presented at American Academy of Neurology Annual Meeting

... treatment at the interim analysis cut-off and were included in the descriptive analysis of maintenance of efficacy. The UPDRS II+III score was almost unchanged from week 18 to week 33 in both pramipexole groups, while a worsening was observed in placebo patients. In the pramipexole extended release group, the...

Cepheid Announces European Release of First On-Demand Molecular Test for Simultaneous Detection of Mycobacterium tuberculosis (TB) and Resistance to Rifampicin

...where testing is needed." Currently, the most common testing method for TB is sputum microscopy , or the smear test, that has remained largely unchanged in its sophistication and sensitivity for over 100 years. The smear test has been proven to only detect around half of all active TB cases and is not ...

Schering-Plough Announces Results of the Early ACS Trial

...tide infusion was continued for 18-24 hours post-procedure. If provisional study drug was not administered pre-PCI, the initial infusion was continued unchanged for 18-24 hours post-PCI. If a thrombotic complication occurred after the wire crossed the lesion, investigators could request a bailout PCI kit conta...

Preterm Births Rise 36 Percent Since Early 1980s

...lso noted an increase in preterm births to Hispanic women, while rates were unchanged for non-Hispanic whites and blacks. However, black women continue to have t...tor for preterm birth, have begun to stabilize. The rate of twin births was unchanged in 2005 and 2006, and triplets and higher order multiples declined 5 percen...

Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH

... associated with a 12-fold likelihood of an improvement in CKD level (P<0.001;CKD improved in 41 percent (12/29) of patients, CKD was unchanged in 55 percent (16/29), CKD worsened in 3.4 percent (1/29)). The drug appeared to be safe and well tolerated in study patients. The mo...

Poniard Pharmaceuticals Announces Final Top-Line Results from Phase 1 Trial Demonstrating Positive Bioavailability with Oral Picoplatin

...in administered intravenously in patients with advanced solid tumor malignancies. Bioavailability refers to the fraction of an administered dose of an unchanged drug that reaches systemic circulation. In the first part of this two-part trial, patients with advanced solid tumor malignancies were randomized to a...
Unchanged in Medical Products

Heidelberg Retina Flowmeter (HRF)

Description:...s scanned two-dimensionally. Light reflected or scattered at moving objects is frequency shifted due to the optical Doppler effect. It interferes with unchanged light reflected at surrounding tissue. The interference causes characteristic temporal intensity variations of the measurable reflected light intensit...
Company:Heidelberg Engineering, Inc.

BioPro Great Toe Joint

Description:...e foot undisturbed. The procedure used to implant the BioPro Great Toe allows for minimal bone resection. The design for the great toe has remained unchanged for 40 years....
Company:BioPro Implants

Simplex™ P Bone Cement

Features:... The unique chemical composition of Simplex™ P, unchanged for forty years, leads to its outstanding performance. Excellent viscosity and porosity characteristics that add up to superior fatigue strength and...
Company:Stryker Corporation

Simplex™ P Bone Cement with Tobramycin

Features:... The unique chemical composition of Simplex™ P, unchanged for forty years, leads to its outstanding performance. Excellent viscosity and porosity characteristics that add up to superior fatigue strength and...
Company:Stryker Corporation
Unchanged in Medical Definition

Depolarization-induced suppression of inhibition

...of spontaneously evoked inhibitory post-synaptic currents ( IPSCs ), caused by the release of a single pre-synaptic vesicle filled with GABA, remained unchanged and 2) The cellular responses to exogenously applied GABA remained the same. These observations suggested that no changes occurred in the post-synapti...
Unchanged in Medical Dictionary

Pleurisy

... (pneumonia, tuberculosis), rheumatic diseases, chest trauma, ... Pleurisy Symptoms, Treatments and Medications ... If the fluid content remains unchanged by the disease, the pleurisy is said to be dry. ... Pleurisy &mdash; Comprehensive overview covers symptoms, causes, diagnosis and trea...
Unchanged in Biological News

Freshwater fish at the top of the food chain evolve more slowly

...ther fish, largemouth bass and fellow fish-feeders have remained relatively unchanged compared with their insect- and snail-eating cousins. As these fishes becam...and other centrarchids that feed primarily on fish have remained relatively unchanged over time. Once they evolved the optimal size and shape for catching fish ...

Scientists discover gene mutation responsible for hereditary neuroendocrine tumor

...ed on to study its potential role in human disease." Sdh5 is a mitochondrial protein that is highly conserved, meaning that it has remained largely unchanged throughout the course of evolution and likely performs similar essential cellular functions in both yeast and humans. Rutter and his colleagues discov...

Two dietary oils, two sets of benefits for older women with diabetes

...ver the course of the study to account for the potential for calorie intake or exercise to affect the results, Belury said. Physical activity remained unchanged throughout the study, and no significant differences were seen between the two groups' reported calorie intake. The study showed that CLA supplemen...

Female human embryos adjust the balance of X chromosomes before implantation

...that this mechanism of compensating for gene dosages has remained basically unchanged throughout evolution and is probably the same in all mammals that have thei...ent from other placental mammals, suggesting that it has remained basically unchanged throughout evolution," said Ms van den Berg. "Early failure to perform c...

City rats loyal to their 'hoods, scientists discover

...nearly two pounds and transmit a variety of diseases to humans. Despite expensive eradication efforts, the number of rats in Baltimore has remained unchanged over the past 50 years, says scientist Greg Glass of Johns Hopkins, who co-authored the Molecular Ecology paper with other researchers from Johns Hopk...

Elephant shark genome sequence leads to discovery of color perception in deep-sea fish

...ility of which will then enable scientists to explore the important functional elements in both the human and elephant shark genome that have remained unchanged during the last 450 million years of evolution." The findings reported in Genome Research and Molecular Biology and Evolution were generated le...

Dancing 'adatoms' help chemists understand how water molecules split

...etsky points out that this shows that water itself can work as a catalyst. A catalyst is a molecule that can help a chemical reaction along and remain unchanged by the experience. "Water is required to move the adatoms around, but like a catalyst it is not consumed in the reaction," he said. "You start with...

'Experiment of nature' examines how mother's diet may impact on child's health

...50% of our DNA from our mothers and 50% from our fathers. Apart from the occasional mutation, deletion or duplication of information, this DNA remains unchanged between generations. The environment, for example our diet, whether we smoke, and the toxins that we encounter in our daily life, can cause change...

Life secret exposed: Scientists unlock mystery of molecular machine

...he ribosome likely followed an ordered series of steps to form the structure found in the first living cell. To this day, that structure exists almost unchanged in our own cells. Chemists have been able to observe many examples of self-organizing behavior with simple molecules, yet explaining the complex s...

Hypertension and cholesterol medications present in water released into the St. Lawrence River

...reted by the human body in urine and end up in municipal wastewater. Chemotherapy products, such as methotrexate, are excreted by the body practically unchanged (80 to 90 percent in their initial form). Chemotherapy for fish? The pharmaceutical compounds studied were chosen because of the large quantitie...
Unchanged in Biological Technology

InterMune Reports Second Quarter 2009 Financial Results and Business Highlights

... collaboration with Roche was $1.6 million in the first six months of 2009, unchanged from the same period of 2008. R&D expenses were $47.4 million...ed its 2009 financial guidance for revenue and operating expenses, which is unchanged from the guidance initially provided on February 26, 2009. Revenue:...

Shire plc: Core Portfolio of Products Delivers 20% Sales Growth

...y pro-active cost management, our business is well placed to deliver on our unchanged guidance framework for 2009 and looking ahead we reiterate our aspiration o...nce framework for Non GAAP diluted earnings per ADS for 2009, which remains unchanged from that provided in our Q3 2008 earnings release. At that time, and in su...

Sanofi-aventis Announces Second Quarter 2009 Results

...oved by 5.1 points to 41.0%. Net financial expenses were virtually unchanged at euro 70 million. Financial expenses rose slightly, reflecting the change...evelopment expenses rose by 3.7% to euro 2,260 million, and were virtually unchanged (up 0.2%) at constant exchange rates. This figure includes euro 54 million ...

NeoGenomics Reports Second Quarter 2009 Results

...by 7%. Gross profit margin of 55% was essentially unchanged from last year. Selling, general & administra...amp;A expenses as a percentage of revenue remained unchanged from Q2 08 at approximately 53%. Net Income was $...versus last quarter. Gross profit margin remained unchanged from Q1 09 at approximately 55%. Significant inve...

Encorium Group Completes Sale of its U.S. Business to Pierrel Research USA; Announces Management Changes

...as extended employment to substantially all of Encorium's U.S. employees. As a result, Pierrel expects that the U.S. operations will continue largely unchanged and that it will be able to seamlessly continue to deliver the services our customers depend on. Encorium has obtained authorizations from its affect...

China-Biotics, Inc. Reports Fourth Quarter and Full Year Fiscal 2009 Financial Results

...tail stores and increased salary expense stemming from new hires to support the Company's expansion. Operating income was $5.7 million, largely unchanged from fiscal 2008, while operating margin was 36.7%. Total other income was $1.1 million, compared to total other income of $3.6 million in the ...

Lethality of H1N1 Influenza Virus Increasing According to Latest Analysis of Virus Peptide Genomic Data

...ean of 3.2+/-3.7 in 2009 (p<0.001). The Replikin Count of the Lethality Gene in 836 previous H1N1 influenza virus isolates has remained essentially unchanged (at 2) since 1933. These analyses were conducted by the Boston-based biotech firm Replikins, Ltd. ( http://www.replikins.com ) using its FluFo...

AEterna Zentaris Discloses Preliminary Phase 2 Trial Results for Perifosine in Combination with Radiotherapy for Non-Small Cell Lung Cancer

...l rate at one year." Paul Blake, M.D., Senior Vice President and Chief Medical Officer at AEterna Zentaris,"In light of these neutral results and an unchanged safety profile, we can concentrate our efforts on the disease targets of both multiple myeloma and metastatic colon cancer where, unlike the non-small...

BioMarin Announces First Quarter 2009 Financial Results

...ompanies will be written down to zero by the end of the year. 2009 Guidance All revenue and selected income statement guidance remains unchanged from the press release issued February 18, 2009 with the exception of research and development expense, impairment loss on investments and non-GAAP ne...

Shire begins the year with a strong performance

...hat our business is well positioned to deliver on our previously stated and unchanged 2009 guidance framework and looking ahead, we also reiterate our aspiration...nce framework for Non GAAP diluted earnings per ADS for 2009, which remains unchanged from that provided in our third quarter 2008 earnings release. At that time...
Unchanged in Biological Definition

Extinction

...inst superior competition. A typical species becomes extinct within 10 million years of its first appearance, although some species survive virtually unchanged for hundreds of millions of years. Descendants may or may not exist for extinct species. Daughter species that evolve from a parent species carry...

Hardy-Weinberg principle

...at the condition for this is q^2 = pr. And since q_1^2 = p_1r_1, whatever the values of p, q, and r may be, the distribution will in any case continue unchanged after the second generation The principle was thus known as Hardy's law in the English -speaking world until Stern ( 1943 ) pointed out that i...

Speciation

...subject of debate, as is the speed with which they occur. Palaeontologists Niles Eldredge and Stephen Jay Gould argued that species usually remain unchanged over long stretches of time, and that speciation occurs only over relatively brief intervals, a view known as punctuated equilibrium . It is entire...

Unsolved problems in biology

...ife narrow or broad? How did life originate and diversify in hundred millions of years? Why, after rapid diversification, do microorganisms remain unchanged for millions of years? Did life start on this planet or was there an extraterrestrial intervention (for example a meteor from another planet)? Why h...
Unchanged in Biological Dictionary

Gene frequency

...allele is as a proportion ... How does a change in gene frequency come about? ... Back to Point 1 -- since gene frequencies tend to remain unchanged in a large, ... gene frequencies through many generations. ... gene and "q" represent the frequency of the recessive, then the sum of p and...

Evolutionarily conserved

... Gene, evolutionarily conserved : A gene that has remained essentially unchanged ... Online Medical Dictionary and glossary with medical definitions ... Evolutionarily conserved gene: A gene that has remained essentially unchanged ... An article published in the open-access journal PLoS Geneticsreports...
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