Bound for destruction: Ubiquitination protects against improper Notch signaling
The is an important molecular signaling mechanism whose existence has beenknown, or at least hinted at, for nearly a century since theidentification of a mutant strain of Drosophila fruit flies with“notched?wings in Thomas Hunt Morgan’s lab in 1910. Later studiesrevealed that the Notch gene encodes a receptor protein tha...Ubiquitin/Proteasome Fraction II Extract from GeneTex
Description:Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs...Ubiquitin Fraction I from ABR-Affinity BioReagents
Description:Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstruct...Ubiquitin Fraction I Extract from GeneTex
Description:Proteolytic degradation is critical to the maintenance of appropriate levels of short-lived and regulatory proteins as important and diverse as those involved in cellular metabolism, heat shock and stress response, antigen presentation, modulation of cell surface receptors and ion channels, cell cycle regulation, transcription, and signalling factors. The ubiquitin-proteasome pathway deconstructs...Ubiquitin Related I Sampler Kit from BD Biosciences Pharmingen
Description:Ubiquitin Related I Sampler Kit 10 mu g each...Rigel Ubiquitin Ligase Program Identifies Molecules With Anti-HIV Activity
Rigel Program to be Presented at Keystone Scientific Meeting SOUTH SAN FRANCISCO, Calif., March 27, 2007/PRNewswire-FirstCall/ -- Rigel today announced that YonchuJenkins, Ph.D., Associate Director of Virology, will be presentingon the company's efforts to develop a small molecule therapeutic totreat patients with the Human Immunodeficiency Virus (HIV)infection at the Keystone Symposium i...