UVa

Sex chromosome genes influence aggression andmaternal behavior, say UVa researchers

It has been well documented that, across human cultures and in most mammals, males are usually more aggressive and less nurturing than females. It's simple to blame male hormones, like testosterone, for male behavior such as aggression. But maybe it's in our genes, too. Indeed such social behavior also has a genetic basis, according to new research on mice by neuroscientists at the Univers...

H9N2 avian flu vaccine paired with adjuvant provokes strong human immune response at low doses

When combined with an immune-boosting substance called an adjuvant, low doses of an experimental vaccine against a strain of avian influenza (H9N2) provoked a strong antibody response in human volunteers, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. The clinical trial of 96 adults was conducted...

UVa researchers seek to unlock broccoli's cancer fighting secret

After all these years, mom was right. She knew broccoli was good for you, she just didn't know it was this good. "Everyone knows broccoli is good for you and that it contains compounds known to lessen the occurrence of some types of cancer. We want to know how these compounds work and what their specific targets may be," says Janet V. Cross, Ph.D., Assistant Professor of Pathology at the U...

UVa at Biology Products

Imject Freund's Complete Adjuvant (FCA) from Pierce Biotechnology, Inc.

Description:Imject Freund's Complete Adjuvant (FCA)...
Company:Pierce Biotechnology, Inc.

Freund's Complete Adjuvant from CHEMICON

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Company:CHEMICON

Freund's Complete Adjuvant, Modified, Mycobacterium butyricum from Calbiochem

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Company:Calbiochem

Imject Freund's Incomplete Adjuvant (FIA) from Pierce Biotechnology, Inc.

Description:Imject Freund's Incomplete Adjuvant (FIA)...
Company:Pierce Biotechnology, Inc.

Freund's Incomplete Adjuvant, Modified from Calbiochem

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Company:Calbiochem

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UVa at Biology Technology

Purification of Two Isoforms of Pyruvate Kinase from Nordic Krill Using an UNO Q1 Column, Rev A

Pyruvate kinase (PK, E.C. 2.7.1.40) is one of the key regulatory enzymes of the glycolytic pathway in crustaceans. This enzyme catalyzes the conversion of phosphoenolpyruvate (PEP) to pyruvate and the phosphorylation of ADP to ATP. In addition to the role of PK in aerobic and anaerobic energy metabolism in...

UVa at Medicine News

Sunscreen Blocking UVA Radiation Receives Federal Approval

A type of sunscreen that blocks the kind of ultraviolet radiation which has been linked to some cancers and available only outside the United States, has received// federal approval on Monday. While other sunscreens mainly block UVB rays Anthelios SX contains ecamsule, which is an ingredient that can block ultraviolet A, or UVA, radiation better than other sunscreen ingredients, which a...

Surgery and Adjuvant Therapy Can Work for Pancreatic Cancer

In the largest single-institution retrospective study to date, researchers at Mayo Clinic Cancer Center have shown that giving patients// both radiation and chemotherapy after completely removing invasive pancreatic cancer may improve overall survival rates. The American Cancer Society reports that while the incidence of pancreatic cancer has decreased over the last few years, it rem...

Bird-flu Vaccine Adjuvant Contract Goes to Novartis

Swiss-based global pharmaceutical giant Novartis bagged the contract to make a chemical that would boost the effectiveness of bird-flu vaccines. The $54.8 million contract// was finalised on Wednesday. The company already has more than $300 million in federal contracts to fight a possible bird-flu outbreak in humans. Two other firms were also awarded contracts on Wednesday...

New Adjuvant Breast Cancer Treatments Found Cost-effective

Two new studies have found that new adjuvant treatments for breast cancer are cost-effective at improving survival. Published in the August 1, 2007 issue of Cancer, a journal of the American Cancer Society, the two studies looked at the cost-effectiveness of different drugs for the management of adjuvant therapies for early breast cancer. In a Canadian economic study...

Foot-and-mouth Disease Outbreak Forces Thiruvananthapuram Zoo to Shut Down

The Thiruvananthapuram Zoo has barred the entry of visitors for a week following the outbreak of foot-and-mouth disease . The zoo has reportedly lost its entire stock of Indian gaur (Bos Gaurus) -- a lookalike of the Indian bison - and 12 blackbucks in the week gone by. It was confirmed last Friday that the foot-and-mouth virus -- strain 'O' had caused the death of an...

UVa at Medicine Products

LD Lactate –> Pyruvate

Description:For the quantitative in vitro determination of Lactate Dehydrogenase (LD) in serum and plasma....
Company:Randox Laboratories Ltd.

Pyruvate

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Pyruvate Kinase

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Pyruvate, CSF

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

UVa at Medicine Technology

New Study Shows Doxorubicin Plus Paclitaxel Followed by Weekly Paclitaxel as Adjuvant Therapy for High Risk Breast Cancer Warranted in Place of Doxorubicin Plus Cyclophosphamide Followed by Paclitaxel

22 US Oncology Affiliated Physicians Participate in ASCOProceedings HOUSTON, June 04, 2007 /PRNewswire/ -- A leading cancerresearcher affiliated with the US Oncology Research Networkpresented findings from a randomized, multicenter phase III trialthat compared the disease-free survival (DFS) obtained with tworegimens of adjuvant therapy for patients with high-risk breastcancer. Th...

Updated Overall Survival Data From Pivotal Herceptin Adjuvant Studies in HER2-Positive Breast Cancer

CHICAGO--(BUSINESS WIRE)--Jun 4, 2007 - Genentech, Inc. (NYSE:DNA)today announced updated results from a joint analysis of two PhaseIII clinical trials studying Herceptin(R) (trastuzumab) for theadjuvant treatment of HER2-positive breast cancer. Data presentedat the 43rd Annual Meeting of the American Society of ClinicalOncology (ASCO) showed that, with median follow-up of nearly threeyears...

Vical's Vaxfectin Adjuvant With Needle-free Delivery Enhances DNA Vaccine Performance; Yields Antibody Responses Comparable to Electroporation Without Tolerability Issues

MALAGA, Spain, May 23, 2007 /PRNewswire-FirstCall/ -- VicalIncorporated today announced that in a recently completed animalstudy, a DNA vaccine formulated with the company's patentedVaxfectin(TM) adjuvant and delivered by needle-free injectionyielded significantly higher antibody responses than anunformulated DNA vaccine delivered by needle and syringe. In aseparate animal study, electro...

Vical's Vaxfectin Adjuvant Achieves Dose-Sparing Effect With Seasonal Influenza Vaccine

SAN FRANCISCO, April 11, 2007 /PRNewswire-FirstCall/ -- VicalIncorporated today announced that a seasonal influenza vaccineformulated with the company's Vaxfectin(TM) adjuvant generated upto 60-fold higher antibody responses than an unformulated vaccineat the same dose in a recently completed study in mice. Formulationof sanofi pasteur's Fluzone(R) commercial vaccine withVaxfectin(TM) al...