UCI

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

Scientists at Joslin Diabetes Center have discovered one reason why infants with low birth weight have a high potential of developing type 2 diabetes later in life. In studies of mice, the researchers found that poor prenatal nutrition impairs the pancreas's ability to later secrete enough insulin in response to blood glucose. "The bottom line is that if you don't have delivery of enough...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

Foreveryone doing or reading a paper about microarray-based experiments,reproductibility, especially inter-lab, is the #1 concern. Can I trustthese results? If I redo the same experiment in one month, will I beable to compare both? The NIH recently demonstrated that microarrays experiments performed in d...

Epstein-Barr virus protein crucial to its role in blood cancers

Researchers at the University of Pennsylvania School of Medicine have identified a link between a critical cancer pathway and an Epstein-Barr Virus (EBV) protein known to be expressed in a number of EBV-associated cancers. Their findings demonstrate a new mechanism by which EBV transforms human B cells from the immune system into cancerous cells, which can lead to development of B-cell lymphomas....

Reducing malarial transmission in Africa

There are 300 million cases of malaria each year worldwide, causing one million deaths. Around 90% of these deaths occur in Africa, mostly in young children. One of the greatest challenges facing Africa in the fight against malaria is drug resistance; resistance to chloroquine (CQ), the cheapest and most widely used antimalarial, is common throughout Africa, and resistance to sulfadoxine-pyrimeth...

Researchers identify protein crucial for survival of Lyme-disease bacterium

When the tick-borne bacterium that causes Lyme disease lacks a specific protein that responds to an incoming meal of blood, it is unable to be transmitted from the tick to a new animal host, researchers at UT Southwestern Medical Center have found. The findings suggest that the protein, called BptA, is essential for the bacterium Borrelia burgdorfei (Bb) to survive in the gut of its tick h...

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UCI at Biology Products

Transformance™ competent cell preparation service from Lucigen

Description:Do you need to make your strain of cells competent or increase their transformation efficiency? Take advantage of Lucigen’s unrivalled expertise in producing competent cells. Lucigen’s Transformance Custom Competent Cell Service offers: Quality control p...
Company:Lucigen

pMIR-mU6-Luc, Mouse U6 Luciferase Control Vector from Mirus Bio Corporation

Description:The potential applications for the use of small interfering RNA (siRNA) molecules to silence gene expression via the RNA interference (RNAi) pathway have generated tremendous interest in the cellular and molecular biology fields. siRNA for experimental use can be synthesized in vitro, either chemically or enzymatically, and then transfected into the target cells in vitro or in vivo. A convenient...
Company:Mirus Bio Corporation

pMIR-hU6-Luc, Human U6 Luciferase Control Vector from Mirus Bio Corporation

Description:The potential applications for the use of small interfering RNA (siRNA) molecules to silence gene expression via the RNA interference (RNAi) pathway have generated tremendous interest in the cellular and molecular biology fields. siRNA for experimental use can be synthesized in vitro, either chemically or enzymatically, and then transfected into the target cells in vitro or in vivo. A convenient...
Company:Mirus Bio Corporation

Luciferase Luminescent Assay Kit, LucLite from PerkinElmer

Description:Measurement of light production by luciferase-cDNA transfected cell lines has proven to be a valuable technique in the development of reporter gene assays in which the luciferase is used as an indicator for the transcription of other genes. The choice of the luciferase enzyme is due to advantages such as high sensitivity and relatively simple measurement. With traditional assay systems , signal m...
Company:PerkinElmer

Luciferase Reporter Assay Kit from MBL International

Description:c-Jun N-terminal kinase (JNK) is one of the several main MAP kinase groups Firefly luciferase has been used as a sensitive reporter for studying gene regulation and function. Luciferase provides a 1000-fold increase in sensitivity in comparison to the standard chloramphenicol acetyltransferase (CAT) assay. Firefly luciferase catalyzes the oxidative carboxylation of luciferin, a reaction with the...
Company:MBL International

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UCI at Biology Technology

Versatile Vectors for Ponasterone A- Inducible Control of Gene Expression in Mammalian Cells

Stratagene mammalian expressionsystem allows tightc...

New Yeast Cloning System for Producing Proteins with Native Amino Acid Sequences

Stratagene Cloning Systems, Inc. The ESP LIC cloning and expression system features rapid and high-yieldproduction of recombinant proteins in yeast. This system usesligation-independent cloning (LIC) for efficient and dire...

Stable HeLa Luciferase Reporter Cell Lines Expressing GAL4 Fusion Transactivators

Lisa Hexdall Li Xu Alan Greener Mary Buchanan John Bauer Chao-Feng Zheng Stratagene HLR-CREB, HLR-Elk1, and HLR-cJun, cell lines for...

Separation Reproducibility With the BioLogic Chromatography Systems

Kevin Thornton, PhD, Bio-Rad Laboratories, Inc., Hercules, CA 94547 USA In chromatographic separations, sample component elution times are often used both for identification and to program automated chromatography steps like fraction collection. Therefore, the ability to obtain reproducible...

Dual-Luciferase Quantitation in the LMax Microplate Luminometer (MaxLine Application Note #39)

Evelyn McGown, Ph.D. and Michael Su, M.S. Molecular Devices Corporation, 8/00 Reporter gene assays are used to study eukaryotic gene expression. Dual geneticreporters are commonly used in transient transfections of cultured cells tominimize experimental variability caused by differences in cell number, viabili...

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UCI at Biology Definition

Zona pellucida

, and is requ...

UCI at Biology Dictionary

Zona pellucida

lucent non-cellular membra...

Reducing agent

Pertaining to the <a href="/ ?q=/ Biology-Diction...

Leucine zipper

(homodimmer or heterodi...

UCI at Medicine News

No harm in reducing prenatal check up to 3 - 6 times says WHO report

A world health organisation report says that women with low risk pregnancies, who live in the developing nations, can safely cut down their vists to the doctor during pregnancy to 3 - 6 times during pregnancy instead of the prescribed 8 - 11 visits as in the developed nations. However, these women are not more at risk than women who had more prenatal visits to have a low birth weight bab...

Reducing Lung Cancer Risk

People who stop smoking before they reach middle age can shun most of the dangers of developing lung cancer. There are now twice as many Britishers over the age of 50 who are former smokers compared with those who continue to smoke.// Over the past four decades, Britain has had the largest reduction in lung cancer in the world. One of the authors is Sir Richard Doll, professor of medi...

Type of inhaler used in asthma treatment crucial

Asthma is one of the most prevalent diseases in our society with more than five million people being affected with the disease, in the UK alone. According to a major study in the UK, in which researchers examined the medical records of almost 900,000 asthma patients across the UK, asthma sufferers are dying needlessly because they are not being prescribed the most suitable inhalers. The s...

Reducing the risk for type 2 diabetes

Diabetes is a condition in which blood glucose levels are above normal. People with diabetes have problems converting food to energy. Food is broken down into a sugar called glucose, which is carried by the blood to cells throughout the body. Cells use the hormone insulin, made in the pancreas, to help them process blood glucose into energy. People with diabetes can prevent or delay compl...

Reducing Medication Errors

Around the world, deaths from medical errors are common, people who are hospitalized face the largest risk for medical mistakes.// Studies show in adults, adverse drug events occur in five of every 100 medication orders. A new study led by researchers at Ottawa, shows computerized systems for ordering medications can reduce the number of errors. This is in place of hand-writing the order...

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UCI at Medicine Products

Proven Cruciate Retaining Knee System, standard

Description:StelKast's Proven Knee System is a long term, quality solution based on a clinically proven design. Available in both posterior stabilized and anatomically correct cruciate retaining configurations, the Proven Knee System provides the flexibility needed to address patients' needs. In addition, instrument standardization and ease of identification keeps the user in mind and promotes functional eff...
Company:StelKast Company

Proven Cruciate Retaining Knee System, curved

Description:StelKast's Proven Knee System is a long term, quality solution based on a clinically proven design. Available in both posterior stabilized and anatomically correct cruciate retaining configurations, the Proven Knee System provides the flexibility needed to address patients' needs. In addition, instrument standardization and ease of identification keeps the user in mind and promotes functional eff...
Company:StelKast Company

TC-Plus Solution, PE insert (Cruciate retaining)

Description:The TC-PLUS Solution tricompartmental total knee prosthesis stems from many years of experience with knee arthroplasty. State-of-the-art design and manufacturing technologies have been used in order to achieve optimum biomechanical function as well as a favorable pressure distribution pattern on the polyethylene tibial insert to keep wear to a minimum. The inherent design of the components, and t...
Company:Plus Orthopedics

TC-Plus Solution, PE insert (Cruciate Substituting)

Description:The TC-PLUS Solution tricompartmental total knee prosthesis stems from many years of experience with knee arthroplasty. State-of-the-art design and manufacturing technologies have been used in order to achieve optimum biomechanical function as well as a favorable pressure distribution pattern on the polyethylene tibial insert to keep wear to a minimum. The inherent design of the components, and t...
Company:Plus Orthopedics

TC-Plus Solution, PE insert (Cruciate substituting - ultracongruent)

Description:The TC-PLUS Solution tricompartmental total knee prosthesis stems from many years of experience with knee arthroplasty. State-of-the-art design and manufacturing technologies have been used in order to achieve optimum biomechanical function as well as a favorable pressure distribution pattern on the polyethylene tibial insert to keep wear to a minimum. The inherent design of the components, and t...
Company:Plus Orthopedics

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UCI at Medicine Technology

New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility

EXCLAIM is the First International Study to Show That ExtendedThromboprophylaxis Reduces VTE Risk in Acutely-ill Medical PatientsWith a Statistically Significant 44% PARIS, July 8, 2007 /PRNewswire-FirstCall/ --Sanofi-aventisannounced today the results of the EXCLAIM (EXtended CLinicalprophylaxis in Acutely Ill Medical patients) study, which showedthe benefit of extended prophylaxi...

Cimzia Effective in Reducing Signs and Symptoms of Rheumatoid Arthritis

New Data Presented at EULAR Confirms Efficacy with Either EveryTwo Weeksn or Monthly Dosing BARCELONA, Spain, 14 June 2007 - 7:00 am CET - New pivotal data(RAPID 1 and RAPID 2) presented at the Annual European Congress ofRheumatology (EULAR) show that Cimzia (certolizumab pegol), thefirst PEGylated, Fc-free anti-TNF, combined with methotrexatetherapy has a rapid and significant eff...

Surfaxin (Lucinactant) Long-Term Survival Advantage vs. Comparators Published in Pediatrics

WARRINGTON, Pa., May 31, 2007 (PRIME NEWSWIRE) -- DiscoveryLaboratories, Inc. (Nasdaq:DSCO) announces publication of theone-year follow-up results from its SELECT and STAR Phase 3clinical trials for Surfaxin(r), in Pediatrics, the premier medicaljournal for pediatric healthcare practitioners. The long-term datafrom the SELECT and STAR trials concluded that Surfaxindemonstrated a statisti...

In New Study, Duloxetine Was Equally Effective, Regardless of Switch Method, in Reducing Painful Symptoms in Ssri Non- or Partial-responders with Depression

SAN DIEGO, California, 23 May 2007 - The antidepressant duloxetinehydrochloride was equally effective in reducing painful symptoms indepressed patients who did not respond, or responded onlypartially, to treatment with a selective serotonin reuptakeinhibitor (SSRI), regardless of whether those patients wereswitched from an SSRI abruptly or gradually. This newdata was presented t...

The Lancet Publishes PREVAIL Study Results Showing Lovenox Superiority Over Unfractionated Heparin for Reducing the Risk of Venous ThromboEmbolism in Patients With Acute Ischemic Stroke

Risk of Having a Venous ThromboEmbolism (VTE) is Reduced by aSignificant 43% in Acute Ischemic Stroke Patients Treated WithClexane(R) / Lovenox(R) BRIDGEWATER, N.J., April 20, 2007 /PRNewswire-FirstCall/ --Sanofi-aventis announced the publication of the PREVAIL (Preventionof VTE after Acute Ischemic Stroke with LMWH Enoxaparin) trial inthe April 21st issue of The Lancet. The results of th...

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UCI at Medicine Dictionary

Leucine aminopeptidase

leucine aminopeptidas...

Hallucinations

or <a href="/ ?q=/ Medicine-...

Hallucination

voices or...

Anterior cruciate ligament

strain<...