High-throughput oncogene mutation detection in human cancers by mass spectrometry-based genotyping
Researchers have devised a new method to detect a spectrum of known gene mutations in a variety of cancer genes that they say is both sensitive and cost-effective. They say that if validated, this method of genotyping might ultimately be used in "real time" to match patients to available targeted therapies. Results were presented at the first meeting on Molecular Diagnostics in Cancer Ther...Affymetrix and ParAllele Launch Industry's Most Comprehensive Product Line for Targeted Genotyping
Twenty-eight years after intense selective logging stopped in the region now known as Uganda's Kibale National Park, the red-tailed guenon (Cercophithecus ascanius) is a primate still in decline. The logging practice, scientists report in a new study, changed the ecological balance for these monkeys, leading to behavioral changes and opening the door for multiple parasitic infections. The...NIH neuroscience microarray consortium launches high-throughput genotyping services
The NIH Neuroscience Microarray Consortium today announced that it has added high-density genotyping on both the Affymetrix and Illumina platforms to its list of services. Stan Nelson, the principal investigator at UCLA, says that "adding ultra-high throughput genotyping for its user-base of ~10,000 investigators across the world keeps the Consortium current with the demands of the scientific com...GenomeLab SNPstream Genotyping System from Beckman Coulter
Description:Scalable SNPstream System Delivers 4,600 to Over 3 Million Genotypes Per Day The GenomeLab SNPstream Genotyping System is capable of performing 4,600 to over 3 Million genotypes per day. Part of the GenomeLab family of products*, this automated, scalable, multiplexed system can process up to 48 SNPs in each well of an arrayed 384-well plate, for cost-effective high throughput SNP analysis. Base...Isotyping from Covance Research Products, Inc
Description:CRP is your one stop shopping point for all your custom immunology service needs. We offer free pr...Genotyping Single Nucleotide Polymorphisms with Molecular Beacons
Stratagenes custom molecular beacon synthesis assists in detecting SNPsquickly and easily University of Colorado Health Sciences Center, Denver, Colorado to detect a single nucleotide polymorphism (SNP) in a region of c...Simple, Sensitive Isotyping of Mouse Monoclonal Antibodies
Weiping Yang Matt C. Petre Darrel Holmes Peter L.Pingerelli Stratagene Cloning Systems, Inc. Stratagenes IsoDetect mouse monoclonal antibody isotyping kit is asimple, rapid and sensitive method for identifying mouse monoclonal antibodyisotypes in a single step. Each IsoDetect test card...Microfluidic analysis of multiplex PCR products for the genotyping of Helicobacter pylori
Gastric infection with Helicobacterpylori (H. pylori) is the majorcause of chronic active gastritisand is associated with the pathogenesisof peptic ulcer and gastriccarcinoma. Recent studies using amultiplex PCR (mPCR) basedapproach distinguished differental...Oragene is compatible with TaqMan SNP genotyping
DNA Genotek Inc., Ottawa, ON, Canada DNA collected with Oragene works well with TaqMan SNP Genotyping Assays. SNPs in the thymidylate synthetase and apolipoprotein E genes were reliably detected. Single-nucleotide polymorphisms (S...Pre Implantation Genetic Haplotyping to Identify 6,000 Inherited Diseases
A new technique was developed to test for inherited disease which would in the near future offer better and healthier babies //. The British fertility clinic says that this new procedure would offer hundreds of couples hope and can test for nearly 6,000 diseases. Even testing for diseases which does not have specific mutation can be detected using this technique. Diseases such as Duchenne...Pre-implantation Genetic Haplotyping- A Test to Sift Unhealthy Embryos Records Success
London: Embryonic testing based on the ‘survival of the fittest’ theory, which helps in detecting unhealthy embryos, with a motive to nurture// the healthy ones, has borne fruit. Now, babies have been born to a British Couple, the first in UK, after successfully employing this method of embryonic testing. This method proved a blessing to the parents in question, who carried genes tha...ViroSeq HIV-1 Genotyping System
Description:HIV-1 Genotyping: The genome of the Human Immunodeficiency Virus (HIV-1) undergoes mutations in an infected patient, especially in response to anti-viral drug treatment. Some of the mutations have been shown to render the virus resistant to the action of these drugs, diminishing the effectiveness of the treatment.The detection of mutations in HIV-1 that correlate with drug resistance provides...GenomeLab SNPstream Genotyping System
Description:The GenomeLab SNPstream Genotyping System provides an automated scalable system capable of performing from 4,600 to over 800,000 SNP genotypes per day. Combined with multiplexing capabilities, experimental layouts and operational flexibility, this enables you to process a wide range of studies. SNPstream is a robust solution designed to deliver your intended results faster with less effort, while...The Past, Present and Future of HLA Typing
The Human Leukocyte Antigen (HLA) region, located on the short arm of chromosome 6 (6p21.3), is a highly polymorphic region containing about 200 genes. The HLA region is the human equivalent of the Major Histocompatibility Complex (MHC), and as such contains a set of genes that serve as the backbone of antigen presentation. The Class I proteins, classically involved in presenting endogenous...