Mouse brain tumors mimic those in human genetic disorder
A recently developed mouse model of braintumors common in the genetic disorder neurofibromatosis 1 (NF1)successfully mimics the human condition and provides unique insightinto tumor development, diagnosis and treatment, according toresearchers at Washington University School of Medicine in St. Louis.After validating their animal model, the team made two importantdiscoveries: New blood vesse...Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
Nano-sized particles embedded with bright, light-emitting molecules have enabled researchers to visualize a tumor more than one centimeter below the skin surface using only infrared light. A team of chemists, bioengineers and medical researchers based at the University of Pennsylvania and the University of Minnesota has lodged fluorescent materials called porphyrins within the surface of a polyme...Pulsating ultrasound enhances gene therapy for tumors
High-intensity focused ultrasound emitted in short pulses is a promising, non-invasive procedure for enhancing gene delivery to cancerous cells without destroying healthy tissue, according to a study in the May issue of the journal Radiology. High-intensity focused ultrasound (HIFU) is more powerful than standard ultrasound. HIFU can destroy tumors through long and continuous exposures tha...NSAID drug protects against intestinal tumors in mice, despite poor diet and gene losses
In mouse models of intestinal cancer, use of an anti-inflammatory drug eliminated all of the cancer-causing risks produced by a high-fat Western-style diet - even when several genetic brakes to cancer formation were missing in the animals, say researchers from the Albert Einstein Cancer Center. The investigators, who presented their findings at the 96th Annual Meeting of the American Assoc...Double trouble: Cells with duplicate genomes can trigger tumors
Abnormal cell division that yields cells with an extra set of chromosomes can initiate the development of tumors in mice, researchers at Dana-Farber Cancer Institute have shown, validating a controversial theory about cancer causation put forth by a scientific visionary nearly 100 years ago. The so-called "double-value" cells are produced by random errors in cell division that occur with u...Use of Cellular Phones associated with Increased risk of Brain Tumors
A recent article published by a team in Sweden suggests that there is an increased risk of brain cancer in the areas of highest exposure in patients using digital telephones (Case Control Study on Radiology work, Medical X-Ray Investigations, and Cellular Telephones as Risk Factors for Brain Tumors, Hardell, et al, May 4, 2000, www.medscape.com). Their analysis focused on the effect of different...Radiofrequency Energy Cooks Tumors Without Surgery
Research conducted at the Warren Grant Magnuson Clinical Center shows that by using radiofrequency energy, doctors can now "cook" tumors without actually removing them. The non-surgical technique, used increasingly for kidney and liver cancers, can also be used on cancers elsewhere in the human body. // During radiofrequency ablation (RFA), a tiny needle is inserted into the tumor and...Morphine may excite cancerous tumors
According to a new study, morphine may be combined with tumor growth in mice. At present there is no scientific data that indicates morphine or similar pain medications will lead to increased cancer growth in humans.// However, researchers say their findings warrant further studies for managing cancer pain. Researchers from the University of Minnesota Cancer Center found doses of morp...Treatment Resistant Tumors Can Be Targeted Better Using Botox
Botox, commonly used for cosmetic treatment may play an important role in enhancing the outcome of chemotherapy and radiotherapy, employed in cancer treatment. // Botox is a derivative of Botulinum toxin, a naturally occurring chemical known to cause intestinal poisoning. The toxin has numerous clinical applications such as relieving facial spasms, strabismus and treating muscle hyp...Benign eye tumors being treated
Researchers at the University of Texas feel that they may have found an effective treatment for a type of non-cancerous eye tumor that threatens clear vision.// Using photodynamic therapy, researchers successfully restored vision in three patients who were suffering from intraocular choroidal hemangiomas, which involved serious retinal detachments. Intraocular choroidal hemangiomas are...BRAF V600E Detection of Colon Cancer (Unstable Tumors) by PCR
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Clinical Data Reported on Vidaza in Hematologic Malignancies and Advanced Solid Tumors
HDAC Inhibitor MGCD0103 Demonstrates substantial Response Ratein Two Clinical Trials Clinical Data Presented on Pilot Pharmacokinetic Study of OralAzacitidine Exelixis Reports Integrated Data From Phase II Clinical Trialsof XL999 at ASCO Clinical Data Reported on Vidaza in Hematologic Malignancies andAdva...