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Troponin in Medical News

Roche Cardiac 200 Offers Rapid Cardiac Diagnostics for the Point of Care

...sts per hour and offers a full cardiac marker menu that includes NT-proBNP, troponin I (TnI), CKMB and Myoglobin. The instrument uses a unique internal correcte...dies have shown that Roche Cardiac 200 diagnostic results for NT-proBNP and troponin I are essentially equivalent to core lab results. (2, 3, 4) The R...

Heart Damage After Vascular Surgery Raises Death Risks

...d. The study was to be presented June 12 in Denver at the annual meeting of the Society for Vascular Surgery. The researchers tested the cardiac troponin T (cTnT) levels of the study participants one, three and seven days after their surgery and when they were discharged. Elevated levels of cTnT, a pro...

Finding Hidden Heart Attacks: Saint Francis Hospital is First in Illinois to Detect Hidden Heart Attacks With New Technology

...r a specialized, 64-slice 3-D Computed Tomography (CT) test for the heart; and it was the first hospital in the U.S. Midwest to use the cardiac marker troponin to diagnose heart attacks. Saint Francis Hospital is a part of Resurrection Health Care, which was ranked in the nation's top 20 "Best Places to ...

Biosite Incorporated Issues Voluntary, Nationwide Recall for Cardiac Marker Test

... recovery of quality control samples containing Creatine Kinase MB (CK-MB), troponin I and myoglobin on the affected lot. Although there have been no reported ...o date, low recovery may lead to reporting of falsely low values for CK-MB, troponin I and myoglobin. A root cause investigation has been initiated. The...

Explaining trends in heart attack

...not similarly declined is explained by the greater sensitivity of diagnostic AMI biomarkers; they note, for example, that the detection rate of AMI by troponin was higher than in earlier decades. Another explanation for the decline in AMI mortality rates may be found in a second report from the same Circu...

U.S. Heart Attacks Becoming Less Severe

...it cannot pump blood to the body, decreased by 5.7 percent per year, while the percentage of cases with abnormal biomarkers such as creatine kinase or troponin decreased by a modest, but statistically significant, 0.7 percent a year. The finding comes from the ongoing Atherosclerosis Risk in Communities St...

Quintet of proteins forms new, early-warning blood test before heart attack strikes

... it?" much earlier than existing assays for heart attack, such as tests for troponin proteins I and T. Van Eyk says commercially available tests for cardiac... to take preventive action," and "after some damage has already occurred." troponin lab tests also depend on the heart muscle dying first, which can take hours...

NxStage Applauds Array of Studies To Be Presented at American Society of Nephrology Meeting

...appear to have less volume overload and less evidence for myocardial injury based upon significant reductions in cardiovascular (CV) markers troponin T (cTnT) and proBNP in the home daily dialysis group vs. a matched conventional in-center dialysis cohort (F-PO1706, 11/7, 10:00 AM). -- "...

Study shows emergency physicians have good first instincts in diagnosing heart attacks

... No MI may have had symptoms but, according to the troponin levels throughout their hospital stay, did not act...ck. Patients classified as NSTEMI showed elevated troponin levels when first admitted, usually because their ... classified as EMI did not initially show elevated troponin levels when presenting to the ED, but showed evid...

Response Biomedical Corporation Announces Strategic Partnership with Roche Diagnostics To Commercialize Cardiovascular Tests

...form to other clinical areas where its unique advantages can be leveraged to improve patient care." The RAMP(R) cardiovascular product line includes troponin I, CK-MB, Myoglobin and NT-proBNP Tests. The Company is awaiting U.S. Food and Drug Administration 510(k) clearance before the NT-proBNP Test can be s...
Troponin in Medical Technology

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

.... MDS/MPD disease and systemic mastocytosis may be associated with high eosinophil levels. Performance of an echocardiogram and determination of serum troponin should therefore be considered in patients with HES/CEL, and in patients with MDS/MPD or ASM associated with high eosinophil levels. If either is abno...

Early Data Show Potential for Imatinib Mesylate Tablets to Treat Life-Threatening Form of Pulmonary Artery Disease

.... MDS/MPD disease and systemic mastocytosis may be associated with high eosinophil levels. Performance of an echocardiogram and determination of serum troponin should therefore be considered in patients with HES/CEL, and in patients with MDS/MPD or ASM associated with high eosinophil levels. If either is abno...

Positive Results Prompt US National Cancer Institute to Make Glivec Available to Patients in Post-Surgical GIST Study

...Cardiac screening should be considered in patients with HES/CEL, and patients with MDS/MPD or SM with high level of eosinophils (echocardiogram, serum troponin level). Rare/serious adverse reactions include: sepsis, pneumonia, depression, convulsions, cardiac failure, thrombosis/embolism, ileus, pancreatiti...

Northfield Laboratories Reports Results of Pivotal Phase III Trauma Study

...easons, including direct trauma to the chest. Myocardial infarction and myocardial ischemia are traditionally assessed by EKGs and the cardiac enzymes troponin I and CK-MB, both of which can be altered by direct trauma. Approximately 75% of the patients in this study had abnormal EKGs or elevated cardiac enzy...

Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results

...ithout ST-segment elevation based on their cardiac troponin levels. troponin levels additionally aid in risk stratification. ...quantitative determination of CK-MB, myoglobin and troponin I in whole blood and plasma specimens using EDTA a...
Troponin in Medical Products

Clearview Troponin I (25 Tests)

Description: For the qualitative detection of cardiac troponin I (cTnl) in human whole blood and serum specimens...
Company:Inverness Medical Professional Diagnostics

Clearview Troponin I (5 Tests)

Description: For the qualitative detection of cardiac troponin I (cTnl) in human whole blood and serum specimens...
Company:Inverness Medical Professional Diagnostics

Clearview Troponin I

Description: Clearview Troponin I is a rapid qualitative test for detection of cardiac Troponin I from whole blood or serum samples. It can be used as an aid in the diagnosis of myocardial infarction and can be useful to assess if chest pain is of cardiac or non-cardiac angina (e.g. gastric pain, strained chest...
Company:Unipath Diagnostics Inc.

Acute Care Cardiac Troponin I

Description: The second-generation Dade Behring Acute Care Troponin I (cTnI) method is the first FDA cleared high sensitivity cTnI assay with the low-end precision necessary to meet the ESC/ACC guidelines (CV <10% at the 99th percentile of normal)....
Company:Dade Behring, Inc.

Innotrac Aio! 2nd Generation Troponin I Assay

Description: Innotrac Aio! 2nd generation cardiac troponin I assay is a highly sensitive immunoassay providing quantitative results directly from whole blood in less than 18 minutes. The assay is based on a unique combination of antibodies that enable improved and earlier detection of myocardial damage....
Company:Innotrac Diagnostics

Access® AccuTnI™ Troponin I Assay

Description: According to the National Academy of Clinical Biochemistry guidelines for the use of cardiac markers in coronary artery disease, troponin I is definitive of acute myocardial infarction. The new Access AccutnI assay was designed for rapid turnaround and improved sensitivity and specificity....
Company:Beckman Coulter, Inc.

IMMULITE 2500 STAT Troponin I

Description: IMMULITE 2500 is a high-throughput immunoassay system built around the many positive attributes of the IMMULITE 2000 with the important addition of Logic Driven Incubation (LDI). LDI technology allows assays to be designed for optimal performance with the fastest possible incubation times. ...
Company:Siemens Medical Solutions Diagnostics

IMMULITE 2000 Troponin I

Description: IMMULITE 2000 assays are designed for use with the IMMULITE 2000, a high-throughput, continuous random access immunoassay analyzer. IMMULITE 2000 offers testing efficiency through centralization, and a rapidly expanding menu for effective patient management....
Company:Siemens Medical Solutions Diagnostics

Myocardial Infarction - Myoglobin and Troponin Cassette

Description: Rapid Screen Tests are used by hospitals, clinics and the retail consumers to help analyze many human health conditions. The majority of these products are one-step, lateral flow membrane tests, which are offered in strip, cassette, and stick formats. Other panel formats and flow through membrane t...
Company:Biotech Atlantic, Inc.

IMA ACB Test COBAS Mira Plus, 100T

Description:...n ischemic event, returning to normal level several hours after cessation of ischemia. IMA can be used in conjunction with electrocardiogram (ECG) and troponin as an aid to rule out ACS at presentation-saving time, resources and money....
Company:Inverness Medical Innovations

More>>

Troponin in Biological News

Studies point to novel target for treating arrhythmias

...filament activation and contraction. Mutations in troponin genes had been linked to inherited forms of hypert...evious studies, Knollmann's team demonstrated that troponin mutations associated with HCM increase the sensiti...mined the heart rhythms of mice expressing various troponin mutants that cause HCM and showed that the mice de...

Biophysical Society announces winners of 2008 Student Travel Awards

...ein College of Medicine, in Silico and in vitro Characterization of Cardiac troponin T Mutations Known to Cause Familial Hypertrophic Cardiomyopathy. Nic... Kareen L. Kreutziger, University of Washington, Coupled Interactions of troponin C Ca2+-Binding Kinetics and Strong Crossbridge Formation in Cardiac Muscle ...

Singulex Teams With Wyeth Pharmaceuticals to Translate Pre-Clinical Biomarker Research Into Clinical Study Design

...ross a variety of biological samples from multiple species. Singulex was the first to identify and quantify normal levels and small changes of cardiac troponin I, a protein biomarker used to detect cardiotoxicity and heart attacks, in human plasma. "Singulex's technology extends the clinical utility of new ...
Troponin in Biological Technology

Spectral announces first quarter 2009 results

...es were higher due to improved EAA(TM) diagnostic sales and the consistency of royalty revenues and reagent sales related to the Company's proprietary troponin I products. Operating expenses for the three months ended March 31, 2009 were $1,043,000, compared to $976,000 for the corresponding period in 2009,...

Spectral announces 2008 financial results

...re expected to remain consistent in the next fiscal year. Certain pre-established royalty plateaus were reached in 2007 by a licensee of the Company's troponin I technology, with a resultant reduction in related revenues of $641,000. In future years, a portion of this impact should be offset as revenues from ...

Singulex Closes $19 Million Financing Round

... clinical diagnostic market. Initially, the company will focus on cardiovascular disease risk diagnostics using its assay platform for the biomarker c troponin I (cTnI), a well-validated marker for cardiac necrosis. "Singulex's steady progress in publishing strong data from premier medical schools in the...

Gleevec Receives FDA Priority Review as First Therapy to Reduce Recurrence of Gastrointestinal Stromal Tumors After Surgery

.... MDS/MPD disease and systemic mastocytosis may be associated with high eosinophil levels. Performance of an echocardiogram and determination of serum troponin should therefore be considered in patients with HES/CEL, and in patients with MDS/MPD or ASM associated with high eosinophil levels. If either is abno...

Boston Biomedical Research Institute Maintains Baa3 Rating from Moody's

...e funding, as possible supplemental funding resources." Among the Institute's scientific breakthroughs have been research that paved the way for the troponin Assay, one of the standard tests now used by physicians to determine whether a person is having a heart attack and Hyaluronan, essential for eye surge...

Spectral announces 2007 financial results

...on of products for the life science research and clinical diagnostics markets. Spectral will provide Bio-Rad with its proprietary single chain troponin I reagents, which are now being sold by five major international reagent supply and instrumentation companies. - Upgraded manufacturing fac...

CV Therapeutics Announces Presentations at American Heart Association Scientific Sessions 2007

...Evaluation of the Prognostic Implications of Low Level Elevation of Cardiac troponin Using a New Highly-sensitive Assay for Cardiac troponin I: Results from the MERLIN TIMI-36 Trial; Oral abstract, Monday, November 5...
Troponin in Biological Products

Mouse Anti-Bovine TROPONIN I (CARDIAC & SKELETAL) Monoclonal Antibody, Unconjugated, Clone C5 from AbD Serotec

Description: MOUSE ANTI BOVINE TROPONIN I...
Company:AbD Serotec

Mouse Anti-Human Troponin T Monoclonal Antibody, Unconjugated, Clone 9B1 from Lab Vision

Description: This antibody is specific for human cardiac troponin subunit T, a 31kDa protein involved in transmitting the Ca-binding signals responsible for contraction of cardiac muscle. It reacts with subunit T of the troponin complex in human cells. It also cross-reacts with human skeletal troponin T (23.2% ...
Company:Lab Vision

Mouse Anti-Human Troponin I Monoclonal Antibody, Unconjugated, Clone 12F10 from ABR-Affinity BioReagents

Description: Troponin I Immunogen: Full length native protein (purified) (Human). Storage: -20 C, Avoid Freeze/Thaw Cycles...
Company:ABR-Affinity BioReagents

Mouse Anti-Human Troponin I Monoclonal Antibody, Unconjugated, Clone 22B11 from Santa Cruz Biotechnology, Inc.

Description: Troponin I (22B11)...
Company:Santa Cruz Biotechnology, Inc.

Rabbit Anti-Human S100 A6 Ab-9 Polyclonal Antibody, Unconjugated from Lab Vision

Description:... S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S100 protein is also expressed in the antigen presenti...
Company:Lab Vision
Troponin in Biological Definition

Biomechanics

...es of living tissues. For example, the binding of myosin to actin is based on the biochemical reaction, where C a 2 + and ATP move the troponin and tropomyosin to allow for the crossbridges to bind to the activation sites on the actin. It has been shown that applied loads and deformations...
Troponin in Biological Dictionary

Positive interference

...how to determine whether analytical interference ... patient's positive troponin level was caused by interference from ... ... judged previously as "ne...rence group. ... ... review possible causes of false- positive cardiac troponin test results. ... to RF has been shown to eliminate the false positive i...

Myofibrils

...song lyrics ... Myofibrils [ previous song / next song ] ... It will turn troponin on, troponin on, | Causing the contraction of the myofibrils . ... Information about...
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