Researchers find drug that inhibits acute leukemia cell growth
...ociety of Pediatric Hematology/Oncology (ASPHO).
"There is a certain receptor we now know is expressed in acute myeloid leukemia (AML) cells called tropomyosin
Receptor Kinase A (TRKA)," said Mauricio Ghisoli, M.D., fellow at the Children's Cancer Hospital at M. D. Anderson. "When TRKA gets turned on by a ner...
Tropomyosin in Biological News
Animal food allergens unmasked
...ns found in muscle tissue, are the most important family.
Tropomyosins in mammals, fish and birds are at least 90% identical to at least one human tropomyosin
and none have been reported to be allergenic. In contrast, the allergenic tropomyosins are all from invertebrates such as insects, crustaceans and nem...
Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy
By preventing activation of tropomyosin
by PI(3)K in cells, the researchers prevented hear...so, the researchers reported, when they eliminated tropomyosin
activity altogether, they also maintained heart re...n receptor internalization and identify non-muscle tropomyosin
as an important substrate of the enzyme's activity...
Tropomyosin in Biological Technology
Tropomyosin in Biological Definition
...issues. For example, the binding of myosin to actin is based on the biochemical reaction, where C a 2 + and ATP move the troponin and tropomyosin
to allow for the crossbridges to bind to the activation sites on the actin.
It has been shown that applied loads and deformations can affect the p...