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Tropomyosin in Medical News

Researchers find drug that inhibits acute leukemia cell growth

...ociety of Pediatric Hematology/Oncology (ASPHO). "There is a certain receptor we now know is expressed in acute myeloid leukemia (AML) cells called tropomyosin Receptor Kinase A (TRKA)," said Mauricio Ghisoli, M.D., fellow at the Children's Cancer Hospital at M. D. Anderson. "When TRKA gets turned on by a ner...
Tropomyosin in Biological News

Animal food allergens unmasked

...ns found in muscle tissue, are the most important family. Tropomyosins in mammals, fish and birds are at least 90% identical to at least one human tropomyosin and none have been reported to be allergenic. In contrast, the allergenic tropomyosins are all from invertebrates such as insects, crustaceans and nem...

Newly Discovered Role for Heart Response Enzyme May Yield Better Heart Failure Therapy

...ed phosphorylation. By preventing activation of tropomyosin by PI(3)K in cells, the researchers prevented hear...so, the researchers reported, when they eliminated tropomyosin activity altogether, they also maintained heart re...n receptor internalization and identify non-muscle tropomyosin as an important substrate of the enzyme's activity...
Tropomyosin in Biological Technology

Innovative Tissue Array Technology for High-Throughput Screening of Gene Expression

...issues and cells, and our data confirm that these optimized array slides maintain the morphological integrity of tissues. By immunostaining of the tropomyosin protein and fluorescent labeling of RNA, we verified that the tissues affixed to the Complete View slides retain antigenicity of proteins and reac...
Tropomyosin in Biological Definition

Biomechanics

...issues. For example, the binding of myosin to actin is based on the biochemical reaction, where C a 2 + and ATP move the troponin and tropomyosin to allow for the crossbridges to bind to the activation sites on the actin. It has been shown that applied loads and deformations can affect the p...
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