Finding Cures For Tropical Diseases: Is Open Source An Answer?
There's aparadigm in life science and drug development : only "lucrative""markets" get exploited by R&D companies. In many occasions I'veseen very promising drugs candidates or related research get cannedbecause no money was to be made with it, even if millions would havebeen saved worldwide. The usual strategy to avoid this fate is to finda drug candid...Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
Gene therapy methods that specifically target muscle may reverse the symptoms of a rare form of muscular dystrophy, according to new research in mice conducted by medical geneticists at Duke University Medical Center. Infants born with the inherited muscular disorder called Pompe disease usually die before they reach the age of two. The researchers also said their approach of targeting corrective...An entropy-based gene selection method for cancer classification using microarray data
Accurate diagnosis of cancer subtypes remains a challenging problem. Building classifiers based on gene expression data is a promising approach; yet the selection of non-redundant but relevant genes is difficult. The selected gene set should be small enough to allow diagnosis even in regular clinical laboratories and ideally identify genes involved in cancer-specific regulatory pathways. Here an...Scripps scientists find potential for catastrophic shifts in Pacific ecosystems
Opening the door to a new way of understanding ocean processes and managing and protecting marine resources, a group of researchers at Scripps Institution of Oceanography at the University of California, San Diego, has developed a groundbreaking analysis of the North Pacific Ocean and how dramatic changes can unfold across its waters. The study, published in the May 19 issue of the journal...An (ecological) origin of species for tropical reef fish
Dealing a new blow to the dominant evolutionary paradigm, Luiz Rocha and colleagues from the Smithsonian Tropical Research Institute, Harvard University the University of Florida and the University of Hawaii, report coral reef fish from neighboring habitats may differ more from one another than from fish thousands of miles away. An ecological speciation model for coral reef organisms may spur the...F-7000 Research Grade Fluorescence Spectrophotometer from Hitachi High Technologies America
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Douglas Drake Michelle Cayouette Lisa Filippone Bob LeSchofs Stratagene 4000 Power Supply Stratagene has developed the new SmartPower...Optimizing electroporation parameters
To ensure that maximum transfection rates are achieved, the electroporation parameters should be optimized for each new cell line. The guidelines listed below for determining the ideal electroporation parameters as simply and as quickly as possible are adapted from Eppendorf Brochure...Eppendorf Electroporation Application Notes Your participation is highly welcome !!!
E-mail us your application notes for inclusion in this Eppendorf web page. Each contribution published will be acknowledged with a set of electroporation cuvettes. ...Optimizing electroporation parameters
To ensure that maximum transfection rates are achieved, the electroporation parameters should be optimized for each new cell line. The guidelines listed below for determining the ideal electroporation parameters as simply and as quickly as possible are adapted from Eppendorf Brochure...Eppendorf Electroporation Application Notes Your participation is highly welcome !!!
E-mail us your application notes for inclusion in this Eppendorf web page. Each contribution published will be acknowledged with a set of electroporation cuvettes. ...Loss Of Dystrophin: Common Thread In Cancer And MS Muscle Wasting
Recent research conducted at the Ohio State University shows that a wasting condition responsible for nearly a third of cancer deaths involves the loss of an essential muscle protein that is also lost in people with muscular // dystrophy. The study findings, which appear in the November issue of the journal Cancer Cell, show that muscle cells lose significant amounts of the protein dy...Tiotropium surpasses Ipratropium
Tiotropium significantly improves lung function, dyspnoea and quality of life in patients with chronic obstructive pulmonary disease (COPD) compared to alternative therapy.// Previous studies have suggested that tiotropium may be the only treatment other than smoking cessation capable of reversing the symptoms of COPD. These latest findings are further evidence of the drug’s potential for...Novel Anti-Neutrophilic Effect produced by Salmeterol in mild asthma patients
A recent three-way crossover study over six weeks by clinicians at the National Heart and Lung Institute, Royal Brompton Hospital, London has shown that Salmeterol produced a novel anti-neutrophilic effect among patients with mild asthma. The study was prompted by the long standing argument about the effects of long-acting beta2-adrenergic receptor agonists, such as salmeterol, on inflamm...Stem cells offer hope for muscular dystrophy
Italian researchers said on Thursday they were combining two new and experimental therapies -- using stem cells and gene therapy -- to try to treat muscular dystrophy. Their early work has shown some success in mice but they warned any real progress is years away. Writing in the journal Science, the team lead by Dr. Giulio Cossu of the Stem Cell Research Institute in Milan and the Univer...Hope for Babies Born With Spinal Muscular Atrophy
One in 5,000 babies is born with SMA ( a terminal condition called spinal muscular atrophy ).// Eighty percent of those babies have a severe form of the disease. No treatment has shown effect against this disorder and these babies rarely live until their second birthday . Although children with SMA have many physical disabilities, they do score well on IQ tests. The pathology of SMA is s...Snellen Entropion Forceps - Small - Right
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Description:DU 520 General Purpose UV/Vis Spectrophotometer. Beckman coulter UV/visible spectrophotometers provide ease-of-use and proven technology for a wide range of applications. The affordable DU Series 500 Scanning Spectrophotometers, with easily interchangeable sampling modules, are ideal for routine use. A totally affordable, completely modular UV/V is Spectrophotometer which provides easy sample han...DU 800 UV/Vis Spectrophotometers
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Description:400 Series Spectrophotometer is truly a revolutionary approach to UV-VIS instrumentation. The latest electro-optical technologies are incorporated into a radically new design, resulting in features and performance unprecedented in a laboratory grade UV Visible spectrophotometer....Two Phase III clinical trials on corifollitropin alfa (Org 36286) reach randomization target
OSS, the Netherlands, June 27, 2007-Organon, the humanhealthcare business unit of Akzo Nobel, announced today that twoout of three Phase III clinical trials with corifollitropin alfa(Org 36286), a new long-acting fertility hormone, have reachedtheir randomization target. Corifollitropin alfa is a new recombinant fertility hormone. It isthe first of a new class of gonadotropi...Trophos Publishes ALS Article in Journal of Pharmacology and Experimental Therapeutics
Trophos Describes Identification, Characterization and BroadNeuroprotective Properties of TRO19622 in Journal of Pharmacologyand Experimental Therapeutics Neurodegenerative Disease Specialists Publish Details of a NovelDrug Candidate for ALS That Targets Mitochondrial Proteins MARSEILLE, June 19th, 2007 - Trophos SA, a biopharmaceuticalcompany specializing in the discovery an...