Chinese Medicinal Compound Stops Formation of Cysts in Polycystic Kidney
...ested in Phase I clinical trials as an anti-tumor agent. This study, with mice bred to have a disease like human polycystic kidney disease, used triptolide with a less toxic concentration than that used in cancer chemotherapy trials. At that level, the compound marked reduced cyst formation in the mice co...Triptolide: A Potential Drug for Polycystic Kidney Disease
...r, inflammation, and auto-immune diseases. Crews and colleagues showed that triptolide causes cell growth arrest in certain cell types. Normal kidney tubule...ief of Nephrology at Yale School of Medicine, who discovered the PKD2 gene, triptolide was tested in a mouse model of PKD. Both fewer and smaller kidney cysts for...Blood -- Triptolide, a constituent of immunosuppressive Chinese herbal ...
Triptolide (TPT) is a chemically defined, potent immunosuppressive compound ... Triptolide suppresses T-lymphocyte proliferation by inhibiting interleukin-2 ...Triptolide | [CAS 38748-32-2] | Tocris Bioscience
View and buy high purity Triptolide from Tocris Bioscience, the leading worldwide supplier of high performance life science reagentsTriptolide: A Potential Drug For Polycystic Kidney Disease
A treatment for polycystic kidney disease (PKD), a leading cause of fatal kidney failure worldwide, has been identified by a research team led by Yale biochemist ...