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Triplet in Medical News

National Infertility Organization Honors RMA of New York for Community Support

... Long Island. RMA of New York is a full-service fertility center that consistently achieves high live birth rates, while maintaining low rates of triplet and higher birth outcomes. Highly individualized patient care is offered through seven reproductive endocrinologists, a urologist, a complementary ...

More Assisted Reproduction, But Fewer Multiple Births

...sed from 15.4 percent in 2000 to 13.7 percent in 2002. The percentage of twin pregnancies decreased from 26.5 percent to 25.7 percent, and the rate of triplet pregnancies decreased from 2.9 percent to 2.5 percent. A 47 percent increase in the proportion of frozen embryo transfer cycles was notable becaus...

Mayo Clinic Researchers Say Triple Drug Combination is Promising Option to Treat Metastatic HER2+ Breast Cancer

...ple combination, so we would need to study this treatment against the standard best two-drug treatment in a randomized Phase III study to know if this triplet is more effective." "This regimen seems to be a very reasonable choice, and it offers the added advantage that women who use it do not lose their...

Triple drug combination is promising option to treat metastatic HER2+ breast cancer

...ple combination, so we would need to study this treatment against the standard best two-drug treatment in a randomized Phase III study to know if this triplet is more effective." "This regimen seems to be a very reasonable choice, and it offers the added advantage that women who use it do not lose their ha...

New DNA Test Is Basis for Groundbreaking IVF Refund Plan, Easing Financial Burden for Patients

...ryos," explained Dr. Geoffrey Sher, Executive Medical Director of the Sher Institutes. "This is why, using CGH, our success rates are high, while our triplet rates are almost nil." In peer-reviewed and published clinical data from several studies, SIRM has established that the transfer of even one CHG-...

Give Kids the Gift of Fun and Fitness This Holiday Season

...ke a great case for breaking up a day in the classroom to stimulate bodies and brains," says Laura Fries, Parents' Choice 2008. "As parents of triplet teenagers, we know how important it is for kids to stay fit and start making healthy choices early in life," says Mulholland. Kideosyncrasy Vo...

Test-tube Babies: Mood Swings are Key to Fertility Choice

...unteers were asked about their mood states, their social, sexual and relationship stress and about whether they preferred to have a singleton, twin or triplet pregnancy, and which of these was considered more risky. The investigators found a clear link between a negative mood and a greater willingnes...

Womens Mood Plays a Key Role in Infertility Treatment

...ures infertility-specific social, sexual, and relationship stress. Finally, the women were asked to rate the desirability of having a twin or triplet versus a singleton pregnancy; the perceived likelihood or a twin or singleton pregnancy; and the desirability of SET. Risk taking behaviour wa...

More is not Merry! Proposal to Ration Embryo to Women having IVF

... The fertility caretaker must get its act together to check the perilous trend of twin and triplet births. A recent proposal to the department has suggested a cap on the// embryo, allowing only one embryo at a time. An expert panel set in moti...

HFEA Issues Warning On Risks Of Multiple Births With IVF

...lth problems that it could cause. Angela McNab, the chief executive of the HFEA, said that they were still very concerned about the levels of twin and triplet pregnancies that they believe cause the single largest risk to mothers and their children from IVF treatments. She said that multiple births could cau...
Triplet in Medical Technology

New Study Proves Multiple Births From IVF Can Be Avoided

...mbryo Transfer (eSET) for In Vitro Fertilization (IVF) can almost eliminate triplet pregnancies and also significantly reduce twin pregnancies without compromi... a twin pregnancy." Today, Shady Grove Fertility has one of the lowest triplet pregnancy rates in the nation, having reduced them from 7% in 2001 to 1.5% ...

Kosan Initiates Phase 2 Trial of Alvespimycin, Second-Generation Hsp90 Inhibitor, in HER2-Positive Metastatic Breast Cancer

...lling a Phase 1 trial to investigate alvespimycin plus trastuzumab and paclitaxel to establish the initial safety profile and pharmacokinetics of this triplet regimen and to lay the groundwork for a potential larger Phase 2/3 trial. About Kosan Kosan Biosciences is a biotechnology company advancing two n...

Kosan's Second-Generation Hsp90 Inhibitor, Alvespimycin, Shows 42% Clinical Benefit in Phase 1 HER2-Positive Metastatic Breast Cancer Trial

...s trastuzumab plus paclitaxel regimen to establish a safety profile of this triplet regimen and to lay the groundwork for a potential larger Phase 2/3 trial. W...the Phase 1 trial to add weekly dosing with paclitaxel (Taxol (R)). In this triplet combination regimen, patients will continue to receive trastuzumab at full ...

Telik Announces Telcyta Clinical and Preclinical Presentations at AACR Meeting

...PALO ALTO, Calif., April 09, 2007 /PRNewswire-FirstCall/ -- Telik, Inc. announced that updated clinical data from its multicenter Phase 2 trial of the triplet combination of TELCYTA(R) (canfosfamide HCl, TLK286), carboplatin and paclitaxel will be presented at the 98th annual meeting of the American Associat...

Telik Reports Positive Data Demonstrating Synergy in Combination and Highly Statistically Significant Effect of Telcyta as Maintenance Therapy in First-Line Non-Small Cell Lung Cancer

...nced the presentation today of results from a Phase 2 clinical trial of the triplet combination of TELCYTA(R) (canfosfamide HCl, TLK286), carboplatin and pacli... 8.4 months without TELCYTA maintenance therapy (p= 0.0003, HR 0.40). The triplet combination was generally well-tolerated at all TELCYTA doses evaluated, wi...

NCCN Updates Esophageal and Gastric Cancer Guidelines

...gest ever phase III study in advanced esophageal and gastric cancer, found that Capecitabine may replace 5-FU and Oxaliplatin may replace Cisplatin in triplet regimens used for the treatment of advanced esophageal and gastric cancer. A new page entitled "Principles of Surgery" was added to outline recommen...
Triplet in Medical Definition

Proteopathy

...egeneration (FTLD) (Ubi+, Tau-) TDP-43 Amyotrophic lateral sclerosis (ALS) Superoxide dismutase, TDP-43 Huntington's disease and other triplet repeat disorders (multiple) Proteins with tandem glutamine expansions Familial British dementia ABri Familial Danish dementia ADan ...
Triplet in Biological News

New hope for treatment of neurodegenerative disorder

...oxic mutant Huntington protein. Mutant Huntington contains increased levels of the amino acid glutamine, which is generated by a repetition of the DNA triplet CAG. A normal Huntington gene has a sequence of between six and 34 CAG repeats. Any strand of DNA possessing more than 40 CAG repeats indicates th...

New therapeutic strategy could target toxic protein in most patients with Huntington's disease

...cid glutamine. The key to whether the Huntingtin gene is normal or defective lies in a kind of genetic stutter: a repetitive sequence of the DNA triplet CAG, which codes for the amino acid glutamine. Stretches of CAG "repeats" appear in every human being's Huntingtin gene, but the length varies. Wher...

Scientists crack 40-year-old DNA puzzle and point to 'hot soup' at the origin of life

...'suffix' codons. "When you evolve our theory for a doublet system into a triplet system, you get an exact match up with the number and range of amino acids ...ecules involved in protein synthesis - which only look at pairs of bases in triplet codons, as well as other physical evidence in support of the theory. "As...
Triplet in Biological Technology

New solar energy material captures every color of the rainbow

...tes -- one called a singlet state, and the other a triplet state. Both energy states are useful for solar cell applications, and the triplet state lasts much longer than the singlet state. ...to some solar cell materials. But electrons in the triplet state stayed free 7 million times longer -- up to ...

UW-Eau Claire chemistry faculty get $600,000 in NSF grants

...uments in student-centered, student-driven projects. A $190,000 grant for a project titled "RUI: Cavity Ringdown Spectroscopy of Cyclic Enones in triplet Excited States. By exposing molecules to the right color of light, it's possible to cause the molecules to undergo chemical reactions that otherwise w...

Cyclodextrin enhances room temperature phosphorescence

...tion limits of two typical phosphors, phenanthrene and acenaphthene, were estimated at 5 10 13 M and 1 10 11 M, respectively. Although the excited triplet state is known to be susceptible to oxygen quenchers, inclusion of the lumiphor inside the CD cavity was observed to offer some protection against que...

The use of the Mastercycler gradient for single-cell PCR and preimplantation diagnosis

... provided with the kit. Figure 4 shows a result of a PCR amplifying the triplet repeat at the 3-end of the DM gene. ... Figure 4: Single-cell fluorescent PCR for the 3 triplet repeat in the DM gene in an individual heterozygous for 5 an...
Triplet in Biological Definition

Centriole

...of each centriole are composed of nine triplets of microtubules , each arranged at a right angle such that when looking down the tube, one end of the triplet pair points slightly outwards and the other end points slightly inwards. In animal cells as well as certain algae and fungi, there exists a pair of ...

Ribosome

...code, to the ribosome) which matches the current codon (triplet) on the mRNA to append an amino acid to the polypeptide chain. This is done for each triplet on the mRNA, while the ribosome moves towards the 3' end of the mRNA. Usually, several ribosomes are working parallel on a single mRNA. See also: ...
Triplet in Biological Dictionary

Wobble base pair

... base pair is a G-U and I-U / I-A ... ... other additional information on Wobble from Biology-Online.org dictionary. ... Which base of the triplet pair seems to be the least influential in determining ... ... left figure defines the wobble position where base pairing does not obey the ...

Triplet repeat expansion

...cleotide repeat expansion , also known as triplet repeat expansion , is the ... triplet expansion is caused by slippage during DNA replication. ... Aspects of the topic triplet - repeat - expansion are discussed in the followi...

Termination codon

... In the genetic code, a stop codon is a nucleotide triplet within messenger RNA that signals a termination of translation. Proteins ...t 5, 2009. home > termination codon definition ... A codon is a triplet of adjacent nucleotides in mRNA that ... from the AUG codon to the termi...

Stop codon

... In the genetic code, a stop codon is a nucleotide triplet within messenger RNA that signals a termination of translation. Proteins ar... Stop ! Codon . In the genetic code, a stop codon is a nucleotide triplet within messenger RNA ... the premature termination codon in theta-defensi...

Ribosome

...ries, essays, summaries, research information, and more. ... Global Motions and Correlations in the Ribosome ... The ribosome moves to the next triplet code from 5' to the 3' direction (note arrow on mRNA) ... Introduction to the Ribosome -Endoplasmic Reticulum Unit ... In cell biology, a rib...

Nonsense Mutation

...nal suppressor, SUP-7 X, in ... Online Medical Dictionary and glossary with medical definitions ... The nonsense mutation converts a codon (a triplet of bases) that encodes an ... Nonsense mutation - Wikipedia, the free encyclopedia ... Nonsense mutations . ... Nonsense mutation defini...

Genetic code

...and more. ... for the Genetic Code : An Exposition ... Understand the triplet nature of the genetic code , and know the meaning of the term codon. ... This kind of reasoning led to the proposal of a triplet genetic code . ... Definitions of the important terms you need to kno...

Frameshift Mutation

...tion caused by indels, ie. insertion or deletion of a number of nucleotides that is not evenly divisible by three from a DNA sequence. Due to the triplet nature of gene expression by codons, the insertion or deletion can disrupt... frameshift mutation ( ) n. A mutation in a DNA chain th...

Frame-shift

...tion caused by indels, ie. insertion or deletion of a number of nucleotides that is not evenly divisible by three from a DNA sequence. Due to the triplet nature of gene expression by codons, the insertion or deletion can disrupt... A directed change in translational reading frames that allows...

Frameshift

...tion caused by indels, ie. insertion or deletion of a number of nucleotides that is not evenly divisible by three from a DNA sequence. Due to the triplet nature of gene expression by codons, the insertion or deletion can disrupt... For the progressive rock/metal band, see Frameshift (band...
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