Viral DNA sequence a possible trigger for breast cancer
A small sequence of DNA in the envelope (Env) protein of a mouse breast tumor virus (called MMTV) can transform breast cells into cancer cells, according to a study by Katz et al. in the February 7 issue of The Journal of Experimental Medicine. The ability of this motif to transform cells single-handedly suggests that viral infection may be an important and previously unrecognized trigger for bre...Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats
Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...Source of molecular triggers in cutaneous T cell lymphoma identified
In a study published in the journal Blood, Yale scientists identify the molecular triggers that stimulate Cutaneous T Cell Lymphoma (CTCL) cells to clonally expand into large populations of malignant lymphocytes. CTCL is the most common adult malignancy of T lymphocytes, the white blood cells of the immune system. Finding CTCL triggering factors has been a major goal of Richard L. Edelson...Inflammatory molecules released by pollen trigger allergies
How do pollen particles provoke allergic reactions? A new study in the February 21 issue of The Journal of Experimental Medicine puts some of the blame on bioactive molecules that are released from pollen. These molecules bind to immune cells and cause them to launch a typical allergy-promoting immune response. Pollen from plants exposed to air pollutants produce more of these allergy-provoking c...Key Trigger Of Opioid Withdrawal Symptoms Found
Researchers have discovered an important chemical in the brain's neuronal machinery that triggers some of the withdrawal symptoms of opioid drugs like morphine and heroin. They believe that drugs to inhibit the chemical--called a transporter--could relieve some of the early physical symptoms of withdrawal, such as teeth-chattering, uncontrolled shaking, and jumpiness. Such drugs could bec...BD Biocoat Matrigel Matrix Thin Layer 35 mm Culture Dishes from BD Biosciences - Discovery Labware
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Description:...Chromosome Ends Trigger DNA Damage Response For Telomere Protection
Researchers from the Salk Institute for Biological Studies have suggested that a localized DNA damage response at telomeres after replication is essential for recruiting the //processing machinery that promotes formation of a chromosome end protection complex. Telomeres, the ends of linear chromosomes, represent a problem for the control of genome stability and the DNA damage machinery...Triglycerides Linked To Stroke Risk
Researchers have linked high levels of blood fats called triglycerides to an increased risk of stroke. The findings should encourage physicians to pay closer attention to triglyceride levels.// More effective screening and detection of high blood triglycerides and treatments to modify this stroke risk factor could further reduce the stroke burdens. Doctors have learned that drugs that...Food May Trigger Life-Threatening Asthma
For the first time, food allergy -- especially to peanuts -- has been shown to be a major cause of life-threatening asthma in children. Asthma attacks are the most common reason for children to be hospitalized, say Dr. Graham Roberts from St. Mary's Hospital in London and a team of experts. Despite great strides in treatment, death due to childhood asthma has not dropped. Roughly 50 child...