FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
As any dedicated video game player knows, the first requireme...Use of PET can reduce, may eliminate more strenuous drug development trials with animals
A number of articles explore the use of positron emission tomography (PET) and small animal imaging--nonsurgical techniques that open the door to understanding and treating human diseases--in the April issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine. A major benefit of small animal imaging "is the ability to carry out many studies at various time points with the same...Moffitt-USF head toward first human trials of anti-cancer drug that targets protein AKT
H. Lee Moffitt Cancer Center & Research Institute, working in partnership with the University of South Florida (USF), has discovered a new use for an old, previously discredited anti-cancer drug that could add another weapon in the arsenal against several cancers, including tumors of the breast, ovary, colon, skin and prostate. The compound, tricirbine, was tested at various cancer cen...Why were the HIV prevention trials in commercial sex workers abandoned?
One promising approach to help stem the global HIV epidemic is to give commercial sex workers an HIV medication (such as the drug tenofovir) before they have high risk sex in the hope of reducing their chances of becoming infected, an approach called "pre-exposure prophylaxis" (PREP). But activist groups, including Act Up-Paris have "halted the progress of at least two important clinical trials o...Kenya halts first field trials of GM maize
Kenyan authorities began destroying the country's first genetically modified (GM) maize growing in open field trials. Wilson Songa, Kenya's agriculture secretary and chair of the Natio...What patients want: A story of choice, clinical trials & evidence-based medicine
What is less obvious is that c...ZyStor seeks to raise $15M for clinical trials
ZyStor, which also presented at the 2006 forum, would like to raise an additional $...Prodesse begins clinical trials for flu virus detection
The product, known as ProFlu+, is being billed as a more complete and user-friendly test to help laboratories detect and differentiate several flu viruses, including...ConjuGon raises $3.3 million to fund clinical trials
The Madison-based ConjuGon will use the capital for clinical trials of its treatment for the infections of large wounds, and to fund the developm...Cancer-fighting agent heads for clinical trials
If the compound is found to be safe and effective in forthcoming clinical trials, it could treat forms of non-Hodgkin's lymphoma...Man against HIV – new vaccine ready for human trials
A new vaccine called the TAT vaccine has been developed in Italy as the latest and most exciting HIV vaccine to date. And more importantly it has had a 71% success rate when tested on monkeys. This vaccine is now ready for human testing and this may be the brightest hope for mankind against the destructive HIV. Dr.Barbara Ensoli, Head of the Department of Virology at Italy’s National Hea...How do patients benefit of clinical trials
Many patients undergoing trials of new cancer treatments do not realise that future patients are more likely to benefit than themselves.There can be no progress in treating cancer - or any other disease - unless there are clinical trials. Henceforth what do patients expect from a trial. Doctors in California gathered views from more than 200 patients involved in trials of new cancer treatments....Clinical trials need to be more frank
Doctors should keep their patients informed about being paid to enrol them in a clinical trial. Post-marketing surveillance or phase 4 clinical trials - are a signicnificant part of medical research. It involves giving patients a new drug// and the family doctor reporting any problems that might arise. The post-marketing phase will involve many more patients than those who can take part in previ...First head-to-head trials of once weekly Fosamax and Actonel therapies
The drug major Merck has launched the first two head-to-head clinical trials that compare the efficacy and tolerability of Fosamax (alendronate) once weekly 70mg and Actonel (risedronate) once-weekly 35mg. Fosamax and Actonel, both bisphosphonates indicated for the treatment of osteoporosis in post menopausal women are co-marketed by Aventis and Procter & Gamble through the Alliance for// Better...Pro-Pharmaceuticals Updates Progress of Clinical Trials & Davanat 505 (b)(2) Filings
NEWTON, Mass.--(BUSINESS WIRE)--Jul 9, 2007 - Pro-Pharmaceuticals,Inc. (Amex: PRW), a company "Advancing Drugs ThroughGlycoscience(R)", today updated the progress of its Phase IIclinical trial for first-line treatment of metastatic, unresectablecolorectal cancer patients who are unable to tolerate irinotecanand/or oxaliplatin, and its Phase II clinical trial for first-linetreatment of bilia...From Clinical Cancer Research: Rethinking Therapeutic Cancer Vaccine Trials
PHILADELPHIA, July 3, 2007-- Ongoing therapeutic cancer vaccinetrials have yet to show evidence of vaccines spurring apatient’s immune system to shrink tumors -- yet patients whoreceive these vaccines in trials tend to live longer and respondbetter to subsequent treatment. In the July 1 issue of ClinicalCancer Research, a journal of the American Association for CancerResearch, a te...