FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
As any dedicated video game player knows, the first requireme...NIAID Initiates Trial of Experimental Avian Flu Vaccine
Fast-track recruitment has begun for a trial to investigate the safety of a vaccine against H5N1 avian influenza, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced today. Sites in Rochester, NY, Baltimore and Los Angeles will enroll a total of 450 healthy adults. The clinical sites are part of the NIAID-sponsored V...International trial of two microbicides begins
A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the U...Bird Brains Show How Trial and Error May Contribute to Learning
The adult male zebra finch knows only one scratchy tune learned in its youth, which it performs repeatedly and intensely when females are listening. But occasionally, the finch might improvise, experimenting with a slower, more sultry variation or emphasizing different notes. Neurobiologists studying the finch now say the improvisation arises from a component of a crucial learning circuit...Use of PET can reduce, may eliminate more strenuous drug development trials with animals
A number of articles explore the use of positron emission tomography (PET) and small animal imaging--nonsurgical techniques that open the door to understanding and treating human diseases--in the April issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine. A major benefit of small animal imaging "is the ability to carry out many studies at various time points with the same...ReBlot™ Plus Kit - Trial from CHEMICON
Description:Western blotting is a commonly used technique for studying protein function and localization. Typically, protein samples are electrophoresed on SDS-PAGE and transferred to a membrane such as nitrocellulose or nylon, where they are probed with specific antibodies. Unlike nucleic acid based technologies, which allow reuse of Southern and Northern blots, it has been difficult to reuse Western blots....ChemiLucent Plus Western Blot Enhancing Kit (Trial size) from CHEMICON
Description:ChemiLucent™ Plus is a chemiluminescent signal enhancing reagent that can be used independently to boost the signal obtained with all ECL based Western blot detection kits. ChemiLucent™ Plus is derived from a powerful, innovative proprietary technology. Unlike conjugated complex- or chemiluminescent substrate enhancers, ChemiLucent™ Plus works through a novel mechanism by increa...Interspecies Trial Array 2: N Brain, N Liver, N Muscle, N Kidney from CHEMICON
Description:Chemicon Select Tissue Arrays are intended for laboratory research use only. The individual tissues were fixed in neutral buffered formalin and embedded in paraffin. Tissue identification and diagnosis was performed by certified pathologists. Tissue cores were removed from their paraffin blocks and relocated into a new recipient paraffin block, in an array pattern, using Chemicons Advanced Tis...Interspecies Trial Array 1: N Breast, N Prostate, N Lung, N Colon from CHEMICON
Description:Chemicon Select Tissue Arrays are intended for laboratory research use only. The individual tissues were fixed in neutral buffered formalin and embedded in paraffin. Tissue identification and diagnosis was performed by certified pathologists. Tissue cores were removed from their paraffin blocks and relocated into a new recipient paraffin block, in an array pattern, using Chemicons Advanced Tis...Interspecies Trial Array 3: N Pancreas, N Skin, N Spleen, N Ovary from CHEMICON
Description:Chemicon Select Tissue Arrays are intended for laboratory research use only. The individual tissues were fixed in neutral buffered formalin and embedded in paraffin. Tissue identification and diagnosis was performed by certified pathologists. Tissue cores were removed from their paraffin blocks and relocated into a new recipient paraffin block, in an array pattern, using Chemicons Advanced Tis...What patients want: A story of choice, clinical trials & evidence-based medicine
What is less obvious is that c...ZyStor seeks to raise $15M for clinical trials
ZyStor, which also presented at the 2006 forum, would like to raise an additional $...Prodesse begins clinical trials for flu virus detection
The product, known as ProFlu+, is being billed as a more complete and user-friendly test to help laboratories detect and differentiate several flu viruses, including...ConjuGon raises $3.3 million to fund clinical trials
The Madison-based ConjuGon will use the capital for clinical trials of its treatment for the infections of large wounds, and to fund the developm...Cancer-fighting agent heads for clinical trials
If the compound is found to be safe and effective in forthcoming clinical trials, it could treat forms of non-Hodgkin's lymphoma...Man against HIV – new vaccine ready for human trials
A new vaccine called the TAT vaccine has been developed in Italy as the latest and most exciting HIV vaccine to date. And more importantly it has had a 71% success rate when tested on monkeys. This vaccine is now ready for human testing and this may be the brightest hope for mankind against the destructive HIV. Dr.Barbara Ensoli, Head of the Department of Virology at Italy’s National Hea...How do patients benefit of clinical trials
Many patients undergoing trials of new cancer treatments do not realise that future patients are more likely to benefit than themselves.There can be no progress in treating cancer - or any other disease - unless there are clinical trials. Henceforth what do patients expect from a trial. Doctors in California gathered views from more than 200 patients involved in trials of new cancer treatments....Glenmark’s new molecule to go through trial
Glenmark Pharmaceuticals Ltd today said its newly- found andti-diabetic/anti-obesity molecule will be put into clinical trials by later this year. Mr Glenn Saldanha, Executive Director, Glenmark pharmaceuticals, told newspersons that the company’s R&D team has established ‘proof of concept’ in animals for this molecule.// The global diabetes market is estimated to be in the region of...Clinical trials need to be more frank
Doctors should keep their patients informed about being paid to enrol them in a clinical trial. Post-marketing surveillance or phase 4 clinical trials - are a signicnificant part of medical research. It involves giving patients a new drug// and the family doctor reporting any problems that might arise. The post-marketing phase will involve many more patients than those who can take part in previ...Antisoma Announces Further Data From ASA404 Ovarian Cancer Trial
LONDON, 12 July 2007 - Cancer drug developer Antisoma plc(LSE: ASM, US OTC: ATSMY) today announces new data from its phaseII trial of ASA404 in recurrent, platinum-sensitive ovarian cancer.This trial compares patients receiving ASA404 plus chemotherapy(n=37) with patients receiving chemotherapy alone (n=38). The mainfindings are as follows: * There was no advantage in median time t...