Use of PET can reduce, may eliminate more strenuous drug development trials with animals
A number of articles explore the use of positron emission tomography (PET) and small animal imaging--nonsurgical techniques that open the door to understanding and treating human diseases--in the April issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine. A major benefit of small animal imaging "is the ability to carry out many studies at various time points with the same...UCLA scientists strengthen case for life more than 3.8 billion years ago
Ten years ago, an international team of scientists reported evidence, in a controversial cover story in the journal Nature, that life on Earth began more than 3.8 billion years ago--400 million years earlier than previously thought. A UCLA professor who was not part of that team and two of the original authors will report in late July that the evidence is stronger than ever. Craig E. Mann...New NIAID grants strengthen national biodefense and emerging infectious diseases research network
The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, today announced four-year grants totaling approximately $80 million for two new Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases Research (RCE). The grants to the University of California, Irvine, and Colorado State University (Fort Collins) mark the completi...Engineers discover why toucan beaks are models of lightweight strength
As a boy growing up in Brazil 40 years ago, Marc A. Meyers marveled at the lightweight toughness of toucan beaks that he occasionally found on the forest floor. Now a materials scientist and professor of mechanical and aerospace engineering at UCSD's Jacobs School of Engineering, Meyers said makers of airplanes and automobiles may benefit from the first ever detailed engineering analysis of touca...Warming trend may contribute to malaria's rise
Could global warming be contributing to the resurgence of malaria in the East African Highlands? A widely-cited study published a few years ago said no, but new research by an international team that includes University of Michigan theoretical ecologist Mercedes Pascual finds that, while other factors such as drug and pesticide resistance, changing land use patterns and human migration als...Etoposide from Biotrend Chemikalien GmbH
Description:Antitumour agent and DNA-topoisomersae II inhibitor (IC50 = 59.2 M). IUPAC: [5R-[5alpha,5abeta,8aalpha,9beta(R*)]]-9-[(4,6-O-Ethylidene-beta-D-glucopyranosyl)oxy]-5,8,8a,9-tetrahyd...Human, Porcine Endothelin-1 from Biotrend Chemikalien GmbH
Description:Endothelin-1 (human, porcine) Endogenous potent vasoconstrictor peptide. Displays selectivity for the endothelin ETA receptor and modulates vascular tonus. ET-1, ET-2, and ET-3 are the products of three distinct endothelin genes. ET-2 and ET-3 are similar to ET-1, but differ in two and six amino acids, respectively. All three isopeptides produce strong in vitro vasoconstrictor and in vivo pr...Rosmarinic acid from Biotrend Chemikalien GmbH
Description:Antiinflammatory, cytostatic and anti-viral agent. Inhibits several important steps of angiogenesis including proliferation, migration, adhesion and tube formation of HUVEC cells. Also reduces intracellular reactive oxygen species (ROS) level, H(2)O(2)-dependent VEGF expression and IL-8 release of endothelial cells. Mol...Human, Bovine, Porcine, Rat VIP, aa 6-28 from Biotrend Chemikalien GmbH
Description:VIP (6-28) (human, bovine, porcine, rat) Desiccate at -20 C...Gtporator (4 ml) from GEN-TREND s.r.o.
Description:Highly efficient electroporation solution suitable for transfection of plasmid DNA, oligonucleotides and siRNA. Compatible with all common electroporators....Small-business trends: Intuit sees more mom-preneurs
, the California-based provider of busines...Midwest large cap life science group strengthening in the third quarter
...State investment board keeps an eye on Wisconsin's tech trends
The agenda for this week's meeting of the in...BIO provides forum for Wisconsin to showcase strengths
The Wisconsin delegation will join more than 18,000 executives and scientists from across the world to study the year's developments in biotech research. Produced by th...VC trends, company progress discussed at Mason Wells portfolio meeting
Limited partners, portfolio company executives, and guests of met in Milwaukee to hear a speech from Mark Hessen,...Stay away from strenouous work
Pregnant women whose job is physically demanding - or who do shift work - could face more childbirth problems, say scientists. A major study in the US showed that this heavy work was associated with premature delivery, high blood pressure and underweight babies. Jobs which involved long periods of standing up, shift work and fatiguing work were also significantly linked with prematur...Creatine Helps Strengthen Older Men
Creatine supplements are often used by body builders, and there's some evidence they help increase muscle mass. Could these supplements help maintain muscle in older people? One new study indicates the answer is yes. //Researchers at the University of Saskatchewan studied 33 men aged 60 to 84 who had similar lifestyles and muscle tone. All the men began the same weight training program. H...Blood Pressure Drugs maintain muscle strength
Drugs used to reduce blood pressure could help to keep elderly people fitter for longer by slowing the physical decline that accompanies age.// ACE inhibitors prevent high blood pressure by blocking an enzyme that causes blood vessels to constrict. The drugs also help to preserve muscle strength in patients suffering from congestive heart failure (CHF). Researchers said the drug...Marijuana 'gateway' theory strengthened by study of twins
A new study of 311 sets of same-sex twins in which only one twin had smoked marijuana before age 17 has bolstered the fiercely debated "gateway theory" that pot can lead to harder drugs. The study included 136 sets of identical twins who shared the same genetic makeup and all the participants were 30 years of age, on an average, when they were asked about their teenage drug use. The resea...Miraflow Extra-Strength Daily Cleaner
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Description:Optimum Extra Strength cleaner is a sterile non-preserved cleaning solution for use with fluorosilicone acrylate and silicone acrylate rigid gas permeable (RGP) and all hard contact lenses of any polymeric structure....SPIRIT Clinical Data Reaffirm Strength of Taxus and Promus Drug-Eluting Coronary Stent Systems
SPIRIT FIRST follow-up analysis shows no stent thrombosis or MACEafter one year NATICK, Mass. and BARCELONA, Spain, May 22, 2007/PRNewswire-FirstCall/ -- Boston Scientific Corporation todaywelcomed the results of additional data from the SPIRIT FIRST, IIand III Clinical Trials, reaffirming prior safety and efficacy datafor the market-leading TAXUS(R) Express2(TM) Paclitaxel-ElutingCorona...Acceleron Pharma's ACE-031 Increases Muscle Mass and Strength in Preclinical Studies
LUCCA, Italy--(BUSINESS WIRE)--May 14, 2007 - Acceleron Pharma,Inc., a biopharmaceutical company developing therapeutics for thetreatment of musculoskeletal, metabolic and cancer-relateddiseases, today announced results of a preclinical study withACE-031 that demonstrated the ability of the compound to increasemuscle mass and strength in normal mice and in murine models ofmuscular dystrophy...