New study reveals structure of E. coli multidrug transporter protein
This new study could potentially help researchers find new ways to avoid the problem of multidrug resistance and enhance the potency of existing drug compounds. "The development of antibiotics to treat infectious disease is being seriously undermined by the emergence of drug-...High dopamine transporter levels not correlated with ADHD
Results from a brain-imaging study conducted at the U.S. Department of Energy's Brookhaven National Laboratory in collaboration with Mount Sinai School of Medicine in New York indicate that levels of a brain protein proposed as a diagnostic marker for attention-deficit hyperactivity disorder (ADHD) are not positively correlated with the disease. In fact, the study found lower levels of these "dop...Anti-Vesicular Monoamine Transporter 2 (VMAT2) Polyclonal Antibody, Unconjugated from CHEMICON
Description:Vesicular Monoamine Transporter 2 (VMAT2). An antibody made to the C-terminal VMAT2 peptide detected a major band at ~55 kDa in postnuclear supernatants of CHO transfected with VMAT2 and not in wild type cells (2). Some additional bands, both higher and lower molecular weight, were also detected and remain unaffected by the inclusion of protease inhibitors. Higher molecular weight bands may repre...Anti-Glycine Transporter 2, Neuronal (GLYT2) Polyclonal Antibody, Unconjugated from CHEMICON
Description:Glycine Transporter 2, Neuronal (GLYT2). The antiserum has been tested on tissue sections from the central nervous system. The staining pattern obtained with AB1773 corresponds to the pattern described using in situ hybridization with probes to GLYT2 mRNA and to what has been described for glycinergic neurons. Preabsorption of the antiserum with the immunogen peptide completely abolishes the immu...Anti-Monocarboxylate Transporter 2 (MCT2) Polyclonal Antibody, Unconjugated from CHEMICON
Description:Monocarboxylate (lactate) transporter 2...Anti-K+-Cl- Cotransporter 1 (KCC1) Polyclonal Antibody, Unconjugated from CHEMICON
Description:Recognizes K+ Cl- Cotransporter-1 (KCC1). The immunogen shows no significant sequence homology with other KCCs or CCC.SPECIES REACTIVITIES: The immunogen sequence is 100% conserved in human, mouse, porcine and rabbit. Reactivity with other species has not been confirmed....Mouse Anti-Vesicular Glutamate Transporter 2 (VGLUT2) Antibody, Unconjugated from CHEMICON
Description:Vesicular Glutamate Transporter 2 [VGLUT2]...New insight for dopamine transporter
Researchers of Yale University had discovered a changed version of dopamine// transporter in healthy persons with genetical variations that may be associated with substance abuse or attention deficit hyperactivity disorder (ADHD). Dopamine is a protein produced in the hypothalamus and some areas of the central and peripheral nervous system. Dopamine and its agonists play an important...Transporter offers reliable clues for safer pain medicine
Researchers have zeroed in on a transporter that actually quietens the body’s natural pain killers. This discovery will show the way for potent and non-habit //forming pain killers and will help perceive the pain threshold of AIDS patients. Opioid peptides are natural pain relievers with receptors – first identified because they react to opium – throughout the body, says Dr. Vadivel G...