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Transplantations in Medical News

Punjab Government Told To Explain Illegal Kidney Transplantations

The National Human Rights Commission (NHRC) has called for a report with regard to people allegedly being coerced to sell their kidneys and has issued the Chief Secretary and the Director General of Police of the Indian State of Punjab with a notice. // As many as 300 laborers in the state are rep...

Lupus Foundation of America Seeks Proposals for Research Studies on Childhood Lupus and Stem Cell Transplantation

...s. Stem cells are undifferentiated adult or embryonic cells that give rise to specialized cells, such as blood, bone, heart, etc. While stem cell transplantations are currently being tested and explored in clinics and labs, researchers are only beginning to understand the potential impact and role of adult stem ...

5 Spanish centers join a study for a new leukemia and lymphoma treatment technique

... The Gamida Cell-Teva Joint Venture announced today that five prestigious cord blood transplantations centers in Spain, three in Barcelona and two in Valencia, have joined the ExCell study. Participating clinical sites include, in alphabetical ord...

Stem Cells Buy Freedom From Insulin for Type 1 Diabetics

...ts own beta cells. Restoring the body's innate ability to produce insulin has been the holy grail of diabetes research. Some patients have received transplantations of insulin-producing cells from a donor, but none have remained free of exogenous (outside) insulin for longer than five years, said Dr. Spyros Meziti...

FDA Issues Final Regulations for Genetically Engineered Animals

...enetically engineered microbes are also widely used in medicine to produce drugs. Certain animals are being genetically altered to be used in human transplantations -- for instance, providing cells, tissues or organs that are less likely to be rejected by the human immune system. These include islet cells to help ...

Transplanted fatty livers associated with worse prognosis for patients with HCV

... than 30 percent steatosis and were subjected to more than 12 hours of cold ischemic time. The authors compared their results to outcomes of liver transplantations in individuals with alcohol-induced cirrhosis, as opposed to HCV. They found that donor steatosis greater than 30 percent did not reduce graft surviva...

New System Improves Distribution of Donated Livers

... according to the United Network for Organ Sharing (UNOS). And according to an accompanying editorial in the journal, overall survival rates for liver transplantations normally exceed 90 percent one year after the surgery. A liver transplant is the only hope for long-term survival for people with end-stage liver dise...

FDA Proposes Regulations for Genetically Engineered Animals

...ls of omega-3 fatty acids," he said. Still others are intended to produce drugs. Certain animals are being genetically altered to be used in human transplantations -- for instance, providing cells or tissues or organs that are less likely to be rejected by the human immune system, Lutter said. "These include ...

Arizona Heart Institute Remembers Heart Surgery Pioneer Dr. Michael E. DeBakey

... this time, Dr. Diethrich stood right by Dr. DeBakey's side, first assisting in many of the earliest coronary artery bypass procedures, multiple organ transplantations and other revolutionary procedures which have since redefined the practice of cardiovascular medicine. "Unless you were there, it is impossible to u...

St. Jude Study Reveals a New Function for an Old Enzyme in Fatal Childhood Disease

...Jude Department of Genetics and Tumor Cell Biology and the paper's senior author. "The results also explain how the loss of NEU1 can cause bone marrow transplantations to fail, and therefore suggests that such failures might also be corrected by target therapeutics." The researchers showed that NEU1 controls how ba...
Transplantations in Medical Technology

Kiadis Pharma Announces Positive Clinical Results for ATIR(TM) in Mismatched Bone Marrow Transplantations

AMSTERDAM, December 4 /PRNewswire/ -- Biopharmaceutical company Kiadis Pharma announces today that it has successfully completed treatment of the last patient on its ATIR(TM) phase I/II clinical trial. ATIR(TM), a donor lymphocyte cell based product, is under development to prevent acute Graft ver...

Alexion Reports Positive Results from AEGIS Registration Study of Soliris in Japanese Patients With PNH

...treatment was limited to symptom management through periodic blood transfusions, non-specific immunosuppressive therapy and, infrequently, bone marrow transplantations -- a procedure that carries considerable mortality risk. (6,11) About Soliris Soliris was approved in March 2007 by the U.S. Food and ...

Kiadis Pharma Receives Two Orphan Drug Designations for Reviroc(TM) From the FDA

...for the treatment of follicular lymphoma. Reviroc(TM) is under development for the elimination of cancer cells from an autologous graft in bone marrow transplantations for end-stage blood cancer patients. "This is an important strategic milestone in the development of Reviroc(TM) and we are very pleased with ...

Kiadis Pharma Announces Collaboration With the Julius Maximilians University of Wurzburg, Germany

...ning to initiate a clinical phase III study for mismatched (haploidentical) transplantations in blood cancer patients at the Julius-Maximilians University of Wurzburg. ...ompany focused specifically on complications and limitations of bone marrow transplantations in blood cancer patients. The company has three products in clinical develo...

Long-Term Soliris(R) Therapy Improved or Stabilized Kidney Function in Patients With PNH

...treatment was limited to symptom management through periodic blood transfusions, non-specific immunosuppressive therapy and, infrequently, bone marrow transplantations - a procedure that carries considerable mortality risk. (2,17) About Soliris Soliris was approved in March 2007 by the U.S. Food and Drug Administ...

Kiadis Pharma Announces Promising Phase II Clinical Trial Results for Reviroc

...c is used to eliminate cancer cells from an autologous graft in bone marrow transplantations for end-stage blood cancer patients. Data from the clinical study revealed ...nsplant uses the patient's own bone marrow to serve as a graft. Bone marrow transplantations are broadly recognized as a treatment option for patients suffering from bl...

Soliris Effective in PNH Patients With History of Aplastic Anemia and Myelodysplastic Syndromes

...treatment was limited to symptom management through periodic blood transfusions, non-specific immunosuppressive therapy and, infrequently, bone marrow transplantations -- a procedure that carries considerable mortality risk.(2)(12) Important Safety Information Soliris is generally well tolerated. The most frequen...

Studies Show Efficacy and Safety of Alexion's Soliris in Broad Population of PNH Patients

...ment has been limited to symptom management through periodic blood transfusions, non-specific immunosuppressive therapy and, infrequently, bone marrow transplantations - a procedure that carries considerable mortality risk.(5)(13) About Soliris Soliris was approved in March by the U.S. Food and Drug Administratio...

Velcade (bortezomib) for Injection Based Induction Therapy Delivered High Post-Transplant Complete Remission Rate, a Critical Marker for Increased Overall Survival

...l. The data were presented in conjunction with the prestigious 11th International Myeloma Workshop (IMW) in Kos, Greece. "Historically, stem cell transplantations generated similar response rates regardless of the induction therapy due to the limited efficacy of these therapies. With VELCADE, we now have a power...
Transplantations in Medical Definition

Ramón Carrillo

..." Carrillo's disease " or epidemic acute papillitis; described in detail the cerebral scleroses, during whose investigation he performed many cerebral transplantations ( brain grafts ) between living rabbits; and histologically reclassified the cerebral tumors and the inflammations of the innermost brain envelope...
Transplantations in Biological News

Coating improves electrical stimulation therapy used for Parkinson's, depression, chronic pain

... is still needed, Dr. Keefer said. "The development of new technologies by Dr. Keefer to potentially restore function in wounded tissues and future transplantations is exciting," said Dr. Spencer Brown, assistant professor of plastic surgery who heads research in the Nancy Lee and Perry R. Bass Advanced Plastic Su...

Cryopreservation techniques bring hopes for women cancer victims and endangered species

...es," he noted, pointing out that much of the progress in humans has come as a result of animal experiments. But it is in humans where most successful transplantations of frozen ovarian tissue after thawing have been carried out, and where greatest experience in the field has been gained. Therefore the ESF conference...

Hebrew University study opening new route for combating viruses

...anti-viral therapy aimed at inhibiting the viral microRNA, and it introduces a possible means to suppress the immune system in autoimmune diseases and transplantations by developing synthetic microRNAs that will mimic the action of natural microRNAs. ...

UC Irvine scientists find new way to sort stem cells

...eating stem cell-based therapies. Without a purification process, stem cell transplantations can cause tumors or be rejected by the bodys immune system. In this stud...oblems such as paralysis and memory loss. Scientists believe that stem cell transplantations might be able to restore part of the lost function. With the goal of ide...

Protein may hold key to decreasing organ dysfunction rates in heart transplants

...as potentially responsible for regulating the body's inflammatory response during heart transplants. One of the major complications involved with many transplantations is the damage done to the transplanted heart during and immediately following surgery, known as ischemia and reperfusion (IR). In particular, inflamma...

Stanford doctors advance in bid to turn mice stem cells into blood vessels

...m cell research and tissue engineering. Tissue engineering, the growth of organs and tissues outside the body for replacement, has achieved successful transplantations of a variety of human tissues including skin and corneas. Most recently, a team of researchers at Wake Forest University in Winston-Salem, N.C., perfo...

Plastic surgeons countdown first full facial transplantation

...st resort procedure performed on carefully selected patients on a case-by-case basis." In the studies, doctors used cadavers to perform mock facial transplantations in order to outline the necessary steps to transplant a human face. Through these trials, they were able to visually show the full extent of the proce...

Genetically engineered animals help in scientific research that may benefit children

...equently found in children and is the first cause of end-stage renal disease (ESRD). According to the article, ESRD represents 16.1% of all pediatric transplantations in North America. ...
Transplantations in Biological Technology

Kiadis Pharma Reports ATIR(TM) Clinical Data, Further Supporting its Potential in Mismatched Bone Marrow Transplantations

AMSTERDAM, April 8 /PRNewswire/ -- Biopharmaceutical company Kiadis Pharma reported preliminary clinical data on ATIR(TM) showing its potential in mismatched bone marrow transplantations. Data was presented by the company's principal investigator Dr. Denis Claude Roy during the prestigious Pre...

Five Cord Blood Transplant Centers in Catalonia and Valencia Join a Study to Test a New Technique to Treat Leukemia and Lymphoma

... JERUSALEM, June 3 /PRNewswire/ -- The Gamida Cell-Teva Joint Venture announced today that five prestigious cord blood transplantations centers in Spain, three in Barcelona and two in Valencia, have joined the Excel study. Participating clinical sites include, in alphabetical o...

Stem Cell Innovations' PluriCells(TM) to Form the Basis of a Liver Assist Device to Support Patients Waiting for Transplant.

...erstand the requirements of the mature cell." Liver disease is a serious problem in the United States and worldwide. There are about 6,500 liver transplantations performed each year in the US, with about 16,000 on the waiting list, about 1,800 of whom will die each year without receiving an organ. A liver assi...

USC researchers derive first embryonic stem cells from rats

...e may eventually enable scientists to establish real ES cell lines from a number of other mammals, which could have significant implications for organ transplantations and the development of drug therapies, Ying says. Researchers at USC are currently working on generating the first gene knockout rat through ES cell-b...

Soliris(R) Reduced Measures of Thrombosis and Inflammation, and Decreased Indicators of Pulmonary Hypertension, in Studies of Patients with PNH

...treatment was limited to symptom management through periodic blood transfusions, non-specific immunosuppressive therapy and, infrequently, bone marrow transplantations -- a procedure that carries considerable mortality risk. (5,10) About Soliris Soliris was approved in March 2007 by the U.S. Food and ...

Kiadis Pharma Announces Continued Collaboration With Professor Velardi on its Lead Product ATIR(TM)

...s an important milestone in the development of ATIR(TM) as a revolutionary approach to provide safe and potentially life-saving mismatched bone marrow transplantations as a treatment option for end-stage leukemia patients." Professor Andrea Velardi says: "So far, we have treated 25 blood cancer patients who h...

The First Ever Transplantation World-Wide of Entire Arms at the "Klinikum rechts der Isar" in Munich

...rgery and in the interdisciplinary preparation and planning of operations as well. Furthermore, the clinic's the Centre for Liver, Kidney and Pancreas transplantations has intensive know-how in the field of immunosuppression. PD Dr. Christoph Hohnke and Prof. Edgar Biemer, have been concerning themselves intensivel...

Kiadis Pharma Reports Successful End of Phase II Meeting With FDA for Reviroc

...ent for elimination of cancer cells from an autologous graft in bone marrow transplantations for end-stage blood cancer patients. The FDA agreed that the data from the ... as leukemia and lymphoma. One of the limitations of autologous bone marrow transplantations is the high relapse rate associated with this treatment. This is often caus...

Promising Data ATIR Studies Presented by NIH Investigators

...he AABB annual meeting & TXPO 2007 in Anaheim, California. According to the NHLBI investigators the challenge in the field of allogeneic bone marrow transplantations lies with disease control, Graft versus Host Disease (GvHD) control and donor availability. Doctors Barrett and Mielke have focused on controlling GvH...
Transplantations in Biological Dictionary

Bone cell

...out ... these cell populations is a central focus of the Bone Tissue ... A fact sheet that explains the step-by-step procedures of two types of transplantations used with high-dose ... Bone marrow transplantation (BMT) and ... Bone cells ... They are mature bone cells . ... osteocalcin, osteonectin...
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