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Transglutaminase in Medical News

How to confirm the causes of iron deficiency anemia in young women

...tion and celiac disease with the use of two tests (human recombinant tissue transglutaminase IgA antibodies and anti- H. pylori IgG antibodies) in women aged In th...howed that two simples and widely available tests, such as those for tissue transglutaminase IgA antibodies and anti- H. pylori IgG antibodies, were able to select wom...

The prevalence of gluten-sensitive enteropathy in iron-deficient anemia patients

...rnal of Gastroenterology . In this prospective study, 4120 patients with IDA were enrolled in this study. Anti-endomysial antibody (EMA) and tissue transglutaminase antibody (tTG) levels were evaluated and duodenal biopsies were taken and scored according to the Marsh classification. The diagnosis of GSE was based...
Transglutaminase in Medical Technology

Non-Invasive Diagnostic Tests for Celiac Disease

... systematic review of the evidence regarding screening patients for CD. The results of that review indicate that tests for endomysial (EMA) and tissue transglutaminase (tTG) IgA autoantibodies have over 95 percent sensitivity, and close to 100 percent specificity, whereas biopsy with a strict cut-off requiring villou...
Transglutaminase in Medical Products

Tissue Transglutaminase Antibody, IgA

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Tissue Transglutaminase Antibody, IgG

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Tissue Transglutaminase Antibody, IgA with Reflex to Endomysial Antibody, IgA Titer by IFA

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Anti-tissue transglutaminase IgG Assay

Description: Tissue transglutaminase (tTg) is a ubiquitous enzyme that catalyzes the cross-linking of proteins. Tissue transglutaminase is also the specific protein that is identified by the endomysial antibody immunofluorescence (EMA) tests (Bio-Rad catalog number 29003 and 29060). Anti-tTg IgA and IgG serol...
Company:Bio-Rad Laboratories

Anti-tissue transglutaminase IgA Assay

Description: Tissue transglutaminase (tTg) is a ubiquitous enzyme that catalyzes the cross-linking of proteins. Tissue transglutaminase is also the specific protein that is identified by the endomysial antibody immunofluorescence (EMA) tests (Bio-Rad catalog number 29003 and 29060). Anti-tTg IgA and IgG serolog...
Company:Bio-Rad Laboratories

Tissue Transglutaminase (tTG) Autoantibody ELISA

Description: ELISA kit for the quantitative determination of autoantibodies to tissue transglutaminase (tTG) in serum....
Company:KRONUS

ImmuLisa Anti-hu tTG IgA ELISA

Description:... An enzyme-linked immuno-sorbent assay for the detectionand quantitation of anti-tissue transglutaminase in serum of patients with Celiac Disease and Dermatitis Herpetiformis....
Company:IMMCO Diagnostics

ImmuLisa™ anti-gliadin(AGA)IgA Kit

Description:... An enzyme-linked immuno-sorbent assay for the detection and quantitation of anti-tissue transglutaminase in serum of patients with Celiac Disease and Dermatitis Herpetiformis....
Company:IMMCO Diagnostics

ImmuLisa™ anti-gliadin-IgG Kit

Description:... An enzyme-linked immuno-sorbent assay for the detection and quantitation of anti-tissue transglutaminase in serum of patients with Celiac Disease and Dermatitis Herpetiformis....
Company:IMMCO Diagnostics

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Transglutaminase in Biological News

Duke team finds compounds that prevent nerve damage

...n's disease-like illness in mutant fruit flies by giving them orally active transglutaminase inhibitors," said Charles S. Greenberg, M.D., a Professor of Medicine and P... author of the paper. The drug blocks the action of an enzyme called tissue transglutaminase (TGM2). TGM2 may damage cells by forming strong bonds between proteins. Suc...

TG2 identified as potential therapeutic target in chemo-resistant ovarian cancer

... HOUSTON, TX Scientists from The University of Texas M. D. Anderson Cancer Center have found overexpression of tissue type transglutaminase (TG2) in ovarian cancer is associated with increased tumor cell growth and adhesion, resistance to chemotherapy and lower overall survival rates. When...

American Chemical Society's weekly PressPac -- Jan. 2, 2008

..., C&EN Deputy Assistant Managing Editor Stu Borman notes that the disease is believed to occur when the protein gluten interacts with an enzyme called transglutaminase 2 (TG2), triggering an autoimmune reaction that damages the small intestine and causes diarrhea, abdominal pain and other symptoms. As a result, peopl...
Transglutaminase in Biological Technology

Senex Biotechnology Announces Presentation of Alzheimer's Disease Drug Discovery Effort

...s of several proteins involved in Alzheimer's disease, including: amyloid precursor protein (APP); BACE1 that converts APP to beta-amyloid; and tissue transglutaminase (TGM2) that cross-links beta-amyloid to form amyloid plaques. Excessive accumulation of beta amyloid and amyloid plaques is believed to cause the symp...
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