Researchers develop first transgenic monkey model of Huntington's disease
Scientists have developed the first genetically altered monkey model that replicates some symptoms observed in patients with Huntington's disease, according to a new study funded by the National Institutes of Health. Researchers are now able to better understand this complex, devastating and incur...
New Transgenic Mushrooms Raise Hope for Mass Production of Human Drugs
Penn State and Agariger, Inc. have patented the technology of making new transgenic
mushrooms, which have increased hope of using mushrooms for the mass production of commercially valuable proteins or useful human drugs.
The technology was introduced by a team of researchers including Char...
Goat’s Milk One of the First Transgenic Food That Benefits Human
According to the researchers at the University of California, Davis it is found that a gene incorporated in to the goat, produces milk that has anti bacterial// enzyme found in human breast milk.
This milk altered the intestinal flora of the pigs and goats which were fed with the milk. Hence th...
Joan Massagué wins BBVA Foundation Frontiers of Knowledge Award in Biomedicine
...as formed by Torsten Wiesel, Nobel Prize in Medicine; Angelika Schnieke, of the Technical University of Munich (Germany); Bruce Whitelaw, an expert in transgenic
animals from the Roslin Institute (United Kingdom); Dario Alessi, of the Scottish Institute for Cell Signalling (United Kingdom); Robin Lovell-Badge, ...
X-rays for early Alzheimer's disease detection
...e a hallmark feature of Alzheimer's disease. Their results will appear in a July 2009 edition of the journal NeuroImage .
Images of the brain of a transgenic
mouse obtained through histology and the corresponding brain region imaged with DEI in computed tomography mode.
Scientists have long known that Alzhe...
Researchers identify 4 new targets for breast cancer
...y resistant to breast cancer and then created four transgenic
strains, each strain expressing one of the recepto... receptors and autotaxin, Mills said. "Now we have transgenic
mouse models to test drugs to go forward against these targets."
The four transgenic
strains of mice have three unusual characteristics...
Transgenic in Medical Technology
Novel Human Tissue Transgenic Cancer Model May Offer Significant
Advance Toward Accurately Modeling Human Cancer
LOS ANGELES & CAMBRIDGE, Mass.--(BUSINESS WIRE)--Apr 18, 2007 -
AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on
the discovery and development of novel, targeted cancer medicines,
presented today findings from its novel human-in-mouse (HIM) tissue
transgenic cancer model syste...
Researchers Create First Targeted Knockout Rats Using Zinc Finger Nuclease Technology
...choice for genome engineering in cells, plants and transgenic
In the first commercial applica...at exclusively express human antibodies encoded by transgenic
human immunoglobulin genes. "Creating a knockout ...00 patients annually. For more information on our transgenic
services offering, see http://www.hmgc.mcw.edu/...
Awardees for the 2009 Young Investigator Grant for Probiotics Research Announced
...eases and International Health at the University of Virginia was selected for her research proposal, "The Influence of Novel Oligopeptides Produced by transgenic
Bacteria on Intestinal Injury Due to C. difficile Infection." After certain inflammatory conditions, drug treatments, or infections, human gut micro...
BN ImmunoTherapeutics Updates on Phase I/II Studies With Breast Cancer Vaccine
...T-cell immune response as compared to
the original version. Furthermore, it proved to be efficacious in additional
tumour immunotherapy models in HER2 transgenic
mice. The immunological
situation regarding HER2 in those mice strongly resembles the situation in
Based on those encouraging data from...
Sangamo BioSciences Provides Update on Company's 2008 Progress and 2009 Objectives
...h Open Monoclonal Technologies (OMT)
and Roche for transgenic
-- Sa...ablishing the utility of ZFNs in
the generation of transgenic
animals and the potential broadening of the
production of knockout transgenic
models beyond mouse models (Doyon et al.,
PharmAthene Initiates Phase I Clinical Trial of Nerve Agent Bioscavenger Protexia(R)
...y and tolerability in humans. Protexia(R),
which is produced in the milk of transgenic
goats, is a recombinant version
of human butyrylcholinesterase (BChE), whic...xia(R).
Protexia(R), which is produced in the milk of transgenic
goats, is a
recombinant version of human butyrylcholinesterase (BChE), a na...
Transgenic in Medical Definition
...d chronic mucocutaneous candidiasis.  AIRE is expressed primarily in the thymus.
A gene knockout of the murine homolog Aire has created a transgenic
mouse model to study the mechanism of disease in human patients.  Research on the knockout mouse has demonstrated that Aire functions through i...
Transgenic in Medical Dictionary
...rground," he said. ... Or at least keep your ... another organism, it replaces that microbe's thymidine gene. ... Steidler demonstrated that his transgenic
microbe completely ... Online Shopping at SpotCost.com - New and used books like The Microbe Files Cases in Microbiology for the Undergraduate...
Transgenic in Biological News
First draft of transgenic papaya genome yields many fruits
A broad collaboration of research institutions in the U.S. and China has produced a first draft of the papaya genome. This draft, which spells out more than 90 percent of the plants gene coding sequence, sheds new light on the evolution of flowering plants. And because it involves a genetically mo...
Is transgenic cotton more profitable?
MADISON, WI, FEBRUARY 11, 2008 -- Transgenic
cotton cultivars were planted on almost 93% of U.S. cotton acres in 2007. Transgenic
cultivars with pest-managing traits are dual-purpose products. The cultivars produce lint and seed, while the expressed propriety traits provide part of the crops insec...
Origen publishes in Nature a robust and versatile method for creating transgenic chickens
Origen Therapeutics announced today that it has succeeded in developing a robust and versatile technology for genetically modifying chickens that, for the first time, puts avian transgenics on a par with transgenic
mice. The company made the announcement in conjunction with the publication of an ar...
Single microRNA causes cancer in transgenic mouse
Scientists in the Ohio State University Comprehensive Cancer Center say that just one, single, malfunctioning microRNA is sufficient to cause cancer in mice. The discovery offers new insight into the development of some forms of leukemia and lymphoma and at the same time underscores the powerful ro...
Restoring a natural root signal helps to fight a major corn pest
...tworm pest include insecticides, crop rotation and transgenic
Bt maize lines that are not yet approved in Europe...tica. Subsequent laboratory studies confirmed that transgenic
plants attracted significantly more nematodes than...use of chemical pesticides," Degenhardt says. "The transgenic
corn plants used in these experiments have no comm...
Promising new treatment for Alzheimer's suggested based on Hebrew University research
...nd the K proteins, as well as engineered human BChE produced in the milk of transgenic
goats at a U.S. company, Pharmathene. The goat- produced protein is prepare...them with the engineered normal protein that is produced in the milk of the transgenic
Transgenic in Biological Technology
EnVivo Pharmaceuticals Announces Reversal of Cognitive Deficits in Alzheimer's Disease Transgenic Mouse Model With Gamma-Secretase Modulator
VIENNA, July 14 /PRNewswire/ -- EnVivo Pharmaceuticals today announced at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD) the reversal of behavioral deficits observed in an Alzheimer's disease transgenic
animal model after chronic oral dosing of a propr...
Sangamo BioSciences and Sigma-Aldrich Announce Research and License Agreement With Roche for the Use of ZFN Technology for Generation of Transgenic Animals Transgenic
Animals to be Developed for Therapeutic and Diagnostic Applications
ST. LOUIS and RICHMOND, Calif., July 9 /PRNewswire-FirstCall/ --
Sigma-Aldrich Corporation (Nasdaq: SIAL ) and Sangamo BioSciences, Inc.
(Nasdaq: SGMO ) today announced a research a...
Sangamo BioSciences Announces License Agreement For the Use of ZFP Technology For Generation of Transgenic Animals
RICHMOND, Calif., April 7, 2008 /PRNewswire-FirstCall/ -- Sangamo
BioSciences, Inc. (Nasdaq: SGMO ) today announced that it had entered into a
License Agreement with Open Monoclonal Technologies (OMT), a private
company based in Palo Alto, California. Under this agreement, Sangamo will
Biolistic Gene Transfer to Generate Transgenic Schistosomes, Rev A
Volker Wippersteg, Katja Kapp, Werner Kunz, and Christoph G Grevelding,
Institute for Genetics, Center of Biological and Medical Research,
Heinrich-Heine-University, D-40225 Dsseldorf, Germany
Schistosomes are parasitic helminths th...
Sangamo BioSciences Reports Second Quarter 2009 Financial Results
...ation of ZFN technology in plant agriculture and in the generation of novel transgenic
animals. Data were published in April in the scientific journal Nature b...rnal Science described a method for the rapid and efficient production of transgenic
rats in which specific genes are deleted or knocked out. The technology op...
Data for SemBioSys' insulin to be presented at the American Diabetes Association's 69th Scientific Sessions
... Poster Hall E on Sunday, June 7th and is entitled: "Analytical Characterization, Safety and Clinical Bioequivalence of Recombinant Human Insulin from transgenic
Plants," by Joseph Boothe and colleagues. The abstract for the presentation is available via the ADA website at http://ww2.aievolution.com/ada0901/in...
Transgenic in Biological Products
Immunodetection of Specific Proteins from QualTek Molecular Laboratories
Peroxidase, Alkaline Phosphatase, Immunogold, and Fluorescent detection
Light, Fluorescent, or Electron Microscopy
Protein Localization in transgenic
Hundreds of Specialty Markers, Including: Vector Detection with - Galactosidase
Proliferation Markers - PCNA, Brdu, Ki67
Neural and Gli...
Company:QualTek Molecular Laboratories
In situ detection of RNA and DNA from QualTek Molecular Laboratories
RNA and DNA Screenings in Animal or Human Cells and Tissues
Double Labeling of RNA / Protein in Cells and Tissues
RNA and DNA Localization in transgenic
Light, Fluorescent, or Electron Microscopy...
Company:QualTek Molecular Laboratories
Neurobiology of Alzheimer's Disease from Promega
Description:...opathology through clinical and diagnostic aspects, the molecular nature of beta-amyloid and tau proteins, the role of apolipoprotein E and the use of transgenic
models. The neurochemistry, in particular potential areas for pharmacological intervention are also discussed....
* Quick & Easy Conditional Knock Out Kit - FRT from Gene Bridges GmbH
Description:... This kit is designed for the fast and simple integration of FRT-sites into large vector plasmids at any position (for the generation of transgenic
mouse models). The included FRT-PGK-gb2-neo-FRT cassette is designed to allow neomycin / kanamycin selection in prokaryotic and eukaryotic cells. It c...
Company:Gene Bridges GmbH
* Quick & Easy Conditional Knock Out Kit - loxP from Gene Bridges GmbH
Description:... This kit is designed for the fast and simple integration of loxP-sites into large vector plasmids at any position (for the generation of transgenic
mouse models). The included loxP-PGK-gb2-neo-loxP cassette is designed to allow neomycin / kanamycin selection in prokaryotic and eukaryotic cells. It...
Company:Gene Bridges GmbH
Transgenic in Biological Definition
...uction of substances like insulin or antibiotics . It can also refer to transgenic
animals or transgenic
plants , such as Bt corn. Genetically altered Mammalian cells, such as Chin...
...(7):1147-8. PMID 8980239
Tang YP, Wang H, Feng R, Kyin M, Tsien JZ. "Differential effects of enrichment on learning and memory function in NR2B transgenic
mice." Neuropharmacology . 2001 Nov;41(6):779-90. PMID 11640933
Hebb, D.O. (1949) The organization of behavior. Wiley, New York.
...sistant. Researchers at Imperial College London created the world's first transgenic
malaria mosquito  , with the first plasmodium resisting species announc...
Ito J, Ghosh A, Moreira LA, Wimmer EA, Jacobs-Lorena M. transgenic
anopheline mosquitoes impaired in transmission of a malaria parasite . Nat...
...om induction of DNA deletions and subsequent selection for deletions in a gene of interest, the application of RNA interference and the creation of transgenic
organisms that overexpress a gene of interest.
The study of macromolecules important in biological inheritance
... systems ranging in complexity from cell-free translation in a test tube to humans.
Finally, a more difficult genetics technique is the creation of transgenic
organisms that overexpress a gene of interest. The resulting phenotype may reflect the normal function of the gene.
Transgenic in Biological Dictionary
plants possess a gene or genes that have been transferred from a different species. Although DNA of another species can be integrated in a plant genome by natural processes, the term " transgenic
plants" refers to... A genetically modified organism (GMO) or geneti...
...own as recombinant DNA... Explanations about transgenic
mouse and the history of biological experimentations ... ©2005 transgenicmouse.com - transgenic
mice - TOP 100 BIOLOGY SITES ... Trangenic Mouse Facility - Home Page ... The UC Irvine transgenic
Mouse Facility is a core facility that provides...
plants possess a gene or genes that have been t...lant genome by natural processes, the term " transgenic
plants" refers to... transgenic
...iques, generally known as recombinant DNA... transgenic
animals , i.e., engineered to carry genes from other species, have the ... Some transgenic
animals are produced for specific economic traits. ... transgenic
Animals The term ' transgenics ' refers to the ...
animals are also becoming useful commercially....ease Animal Models - BSRC Alexander Fleming. transgenic
Animal Models - Biomedcode ... A transgenic
animal is one whose genome has been changed t...
...ic DNA fragments in a complex mixture. ... Southern blotting . ... can be detected by southern blotting . ... Southern Blots analysis of transgenic
mice need copy standards to estimate copy number. ... Southern Blots are commonly used to determine transgene copy number ... Northern blotti...