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Transferrin in Medical News

Retrospective Analysis Finds Treatment of Cancer Chemotherapy Patients With Epoetin Alfa Associated With Lower Drug Cost Than Darbepoetin Alfa

... of pregnancy should be discussed and the need for contraception evaluated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iro...

Diabetes, obesity and hypertension increase mortality in hepatitis C patients

... 40 U/L, AST> 37 U/L in men, and ALT> 31 U/L, AST>31 U/L in women), excessive alcohol use (>10 grams/day in women and > 20 grams/day in men), elevated transferrin saturation (>50%) and positive hepatitis Bs antigen were designated controls without liver disease. HCV patients were compared to HCV-negative individ...

Iron overload: An important co-factor in the development of liver disease in alcoholics

...oad was found in alcoholics, which appeared to be related to the development of liver disease [odds ration for having liver disease in alcoholics with transferrin saturation greater than 45% was 2.2 (95% CI 1.37-3.54)]. Regarding HFE mutations, only H63D was found to be associated with alcoholic liver disease [o...

UCLA and biotech company develop first blood test to measure key hormone that regulates iron

...disease. The current tests do not measure hepcidin but instead measure some of its direct and indirect effects on iron and the iron-binding proteins transferrin and ferritin. The new blood test will directly measure hepcidin, offering more information to clinicians to help diagnose conditions and monitor the ...

Stretching exercises may reduce risk of pre-eclampsia during pregnancy

...ld provide protection against preeclampsia because stretchers produced more transferrin than walkers did, Yeo said. transferrin is a plasma protein that transports iron through the blood and protects aga...

Iron banded worms drying out of blood could be linked to Parkinson's and Alzheimer's

...iseases. Human blood relies on a protein called transferrin to safely transport iron through the bloodstream t... such as Parkinsons, Huntingtons and Alzheimers transferrin takes up iron out of bloodstream and transports it...rbonate to bind to two sites on the surface of the transferrin protein. It then curls around the iron and seals i...

Modeling Simulation Predicts Potential Negative Impact on U.S. Blood Supply if ESA Use Limited for Chemotherapy-Induced Anemia

...gnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or fun...

Updated Analysis of 2001 Epoetin Alfa Study Posted

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...

Ortho Biotech to Submit Official Request for Reconsideration to CMS Regarding ESA Coverage Policy

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...

New Blood Test To Detect Iron Level In Infants

...ely indication of iron status, the investigators say. In this study, 200 healthy infants 9 to 12 months of age underwent both tests, as well as a transferrin saturation test, which is the “gold standard” test for iron deficiency but is impractical for routine screening. Using the optimal CHr cutoff value (e...
Transferrin in Medical Technology

Observational Study Finds Changes in Medicare Reimbursement for Erythropoiesis-Stimulating Agents Associated With Increased Need for Blood Transfusion

... of pregnancy should be discussed and the need for contraception evaluated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iro...

Data From Investigational Use of PROCRIT(R) (Epoetin alfa) Presented at American Society of Nephrology Annual Meeting

...gnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or func...

InVitria Showcases Cell Culture Productivity Enhancers at BioProcess International

... can replace bovine or human sources of albumin or transferrin and provide better productivity, enhanced safety a...romin -- Lacromin has been shown to replace bovine transferrin and human transferrin in cell culture media. In addition, Lacromin is a ...

Observational Studies Assess the Potential Impact of Limiting Erythropoiesis-Stimulating Agent Availability on Frequency of Blood Transfusions

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...

New Data Highlighting Possible Impact of ESA Reimbursement Policies on Patient Care, Nation's Blood Supply, to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...

Data From Ortho Biotech-Sponsored Studies to be Presented at National Kidney Foundation 2008 Spring Clinical Meetings

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...

Ortho Biotech Statement on U.S. Food and Drug Administration Oncologic Drugs Advisory Committee Vote

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functi...

Totality of Available Data Reaffirms PROCRIT(R) (Epoetin alfa) Is Safe and Effective When Used Appropriately as Labeled to Treat Chemotherapy-Induced Anemia

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...

Observational Data Show Transfusion Patterns in Chemotherapy-Induced Anemia Patients Receiving Erythropoiesis-Stimulating Agents

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...

Siemens Healthcare Diagnostics Launches B12, Folate, and Ferritin Tests on Its Dimension vista Intelligent Lab System

... Iron Binding Capacity by photometric methodology; and Haptoglobin, Soluble transferrin Receptor, and transferrin testing by nephelometric methodology. The Dimension Vista Intelligent Lab s...
Transferrin in Medical Products

Soluble Transferrin Receptor

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Carbohydrate Deficient Transferrin for Congenital Glycosylation Disorders

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Carbohydrate Deficient Transferrin for Alcohol Use

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Glycosylated Transferrin

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Beta-2 Transferrin

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Transferrin

Description:... For the quantitative in vitro determination of transferrin in human serum...
Company:Randox Laboratories Ltd.

Transferrin (Liquid)

Description:... For the quantitative in vitro determination of transferrin in Serum...
Company:Randox Laboratories Ltd.

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Transferrin in Medical Definition

Atransferrinemia

... Atransferrinemia is a genetic disorder in which there is absence of transferrin , a plasma protein that transports iron through the blood . Atrans...ed away from heart failure with atransferrinemia. The half-normal levels of transferrin in her parents ' bloodstream supported the notion that this disorder is tr...
Transferrin in Medical Dictionary

TIBC

...ramphenicol. ... Describes when the TIBC and transferrin tests are ordered, how they are used, and what the results of a TIBC or transferrin test might mean Search. Help? TIBC and Transferrin. Formal name: Total iron-binding capacity; transferrin ... be low, but serum iron and TIBC are usuall...

Serum iron

...en ... Serum iron (SI) concentration (μmol/L) in the control and CL groups prior to ... List of 1 disease causes of Increased serum iron transferrin saturation, patient stories, diagnostic guides. Diagnostic checklist, medical tests, doctor questions, ... ... ion; Fe++; Ferrous ion; Iron - s...

Sertoli

... Molecular biology of the Sertoli cell. Griswold MD, Morales C, Sylvester SR. ... The Sertoli cell-mediated iron transport to germ cells via transferrin is the ... The use of Sertoli cell cultures and appropriate biochemical and immunological ... The Sertoli cells have developed a system to m...

Ferritin

...on so your body can use it later. A ferritin test indirectly measures the amount of iron in your blood. ... Relationships of serum ferritin , transferrin saturation, and HFE mutations and ... The mean serum ferritin concentration was significantly lower in Asian men with ... Ferritin is a pro...
Transferrin in Biological News

Rusty worms in the brain

...Alzhiemers. A malfunction of the blood transporter transferrin may be to blame. A team led by Peter J. Sadler at ...ogy (Kanpur, India) has now been able to show that transferrin can clump together to form wormlike fibrils. As re...roven. The researchers deposited iron-loaded human transferrin onto various surfaces under conditions that emulat...

Discovery could lead to better control of hemorrhagic fever viruses

...'s lab by Jonathan Abraham, PhD, an MD-PhD student at HMS, turned out to be transferrin receptor 1 (TfR1), a well-known protein that is key in enabling cells to ta...udies have shown that when the iron level in the body is low, the number of transferrin receptors in tissues increases. Consistent with these findings, Choe's team...

Nanoparticles, nanoshells, nanotubes: How tiny specks may provide powerful tools against cancer

... initiate a self-destruct process called apoptosis in cells with genetic damage. The liposome-antibody complex finds the cancer cell by binding to the transferrin receptor, which is present on the cancer cell surface in high numbers. When this happens, the p53 "payload" moves into the tumor cell. "If we are...

Recombinant DNA technology may enable oral, rather than injectable, delivery of protein drugs

...potential uses of transferrin. "We discovered that transferrin can bind to receptors on the intestinal epithelial...lood stream," Shen says. "Humans naturally produce transferrin to move iron through the blood to the liver, splee...py. After that, the researchers needed to bring transferrin and G-CSF together, a process that is detailed in ...

Novel gene-silencing nanoparticles shown to inhibit Ewing's sarcoma

... classic "Trojan horse" approach, a protein called transferrin that normally delivers iron into cells is modified...s through the bloodstream until it meets up with a transferrin receptor on the surface of another cell. The transferrin binds tightly to a receptor on the cell's surface,...
Transferrin in Biological Technology

InVitria's Animal Free Lacromin(TM) Provides a Cost-Effective Improvement Over Transferrin

SACRAMENTO, Calif., Oct. 23 /PRNewswire/ -- InVitria has released data that shows that Lacromin, a recombinant growth factor for cell culture media outperforms transferrin and provides a cost-effective solution to rising transferrin costs. Because Lacromin is produced in a completely animal-fr...

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

... of pregnancy should be discussed and the need for contraception evaluated. Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functional iro...

Beckman Coulter Announces Fourth Quarter and Full Year 2008 Results; Earnings Outlook Achieved on Strong Fundamentals

...f systems customers can choose from to meet a wide range of test mix and volume requirements. Received FDA clearance for the Access(R) Soluble transferrin Receptor assay and the sTfR/log ferritin index as aids in the diagnosis of iron deficiency anemia and anemia of chronic disease. Launched the ...

InVitria Touts Product Advantages at Cambridge's Cell Culture Conference

...l media.(see http://www.Cellastim.com ) -- Lacromin - Lacromin is recombinant human lactoferrin, a growth factor that also delivers iron similar to transferrin in cell culture media. (see http://www.Lacromin.com ) -- Lysobac - Lysobac is a bacterial cell lysis agent that is more efficient and more consiste...

InVitria Sponsors Cambridge Healthtech's Optimizing Cell Culture Development Conference

... cell media and primary cell media. (see http://www.Cellastim.com ) -- Lacromin -- Lacromin has been shown to replace bovine transferrin and human transferrin in cell culture media. In addition, Lacromin is a strong growth promotant as a cell culture ingredient in mammalian cell culture media. (see http://w...

InVitria Further Strengthens Sales Team with Promotion of Brandy Sargent to Account Manager - Western United States

...imary cell media. -- Lacromin - Lacromin has been shown to replace bovine transferrin and human transferrin in cell culture media. In addition, Lacromin is a strong growth promotant a...

InVitria Expands Sales Team

...n. Cellastim also has been an effective component in stem cell media. -- Lacromin -- Lacromin has been shown to replace bovine transferrin and human transferrin in cell culture media. In addition, at higher inclusion levels, Lacromin is a strong growth promotant as a supplement for mammalian cell culture media...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa)

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...

Ortho Biotech Statement On JAMA Publication Regarding Erythropoiesis-Stimulating Agents

...pregnancy should be discussed and the need for contraception evaluated. -- Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or functi...

Ortho Biotech Modifies Prescribing Information for PROCRIT(R) (Epoetin alfa) Label Reflects Recommendations from Recent FDA Advisory Committee Meetings

...pregnancy should be discussed and the need for contraception evaluated. * Prior to and regularly during PROCRIT therapy monitor iron status; transferrin saturation should be greater than or equal to 20% and ferritin should be greater than or equal to 100 ng/mL. During therapy absolute or funct...
Transferrin in Biological Products

Mouse Anti-Transferrin, N-terminus Monoclonal Antibody, Unconjugated, Clone 236-18241 from Meridian Life Science, Inc.

Description:... MAb to transferrin Dry Ice: No Preservative: NaN3 Availability When Not in Inventory: 14-21 Business Days...
Company:Meridian Life Science, Inc.

Rabbit Anti-TRANSFERRIN RECEPTOR Polyclonal Antibody, Unconjugated from AbD Serotec

Description:... RABBIT ANTI transferrin RECEPTOR...
Company:AbD Serotec

Multiple Affinity Removal System from Agilent Technologies

Description:...nd more with just one device. With this revolutionary system, you can: Remove six targeted, high-abundant proteins: albumin, lgG, antitrypsin, lgA, transferrin and haptoglobin (representing 85-90% of total serum protein mass) Improve the results you get with protein separation methods such as 1DGE, 2DGE and...
Company:Agilent Technologies
Transferrin in Biological Definition

Fungus

...ue to: Fatty acid content of the skin . pH of the skin, mucosal surfaces and body fluids Epithelial turnover Normal flora transferrin Cilia of respiratory tract . When fungi do pass the resistance barriers of the human body and establish infections, the infections are clas...
Transferrin in Biological Dictionary

Transferrin receptor

... transferrin receptor (TfR) is a carrier protein for transferrin . It is needed for the import of iron into the ce...w iron concentrations promote increased levels of transferrin receptor , to increase iron intake into the cell. ...

Serum

... Blood serum is blood plasma without fibrinogen or the other clotting factors (i. ... transferrin saturation = Serum iron / Total iron-binding capacity ... Serum may refer to: The serum is a fluid component of clotted blood and it lacks ...
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