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Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...

Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer

The genome sequence of the parasitic amoeba Entamoeba histolytica, a leading cause of severe diarrheal disease in developing countries, includes an unexpectedly complex repertoire of sensory genes as well as a variety of bacterial-like genes that contribute to the organism's unique biology. The report, which appears in the February 24 issue of Nature, presents the first genome-wide study...

Male circumcision reduces risk of HIV transmission from women to men

The first study to examine the probability ofHIV infection per act of heterosexual sex among a population withmultiple sexual partners has found that uncircumcised men have morethan twice the risk of acquiring HIV than do circumcised men.In the study, published in the Feb. 15 issue of The Journal ofInfectious Diseases, now available online, Jared Baeten and colleaguesfrom the United States...

Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates

The replenishment of missing neurons in thebrain as a treatment for Parkinson disease reached the stage of humantrials over 15 years ago, however the field is still in its infancy.Researchers from Kyoto University have now shown thatdopamine-producing neurons (DA neurons) generated from monkey embryonicstem cells and transplanted into areas of the brain where these neuronshave degenerated i...

The transparent organism: EMBLEM and Carl Zeiss give labs a unique look at life

A novel high-tech microscope will be brought to the marketplace, giving laboratories everywhere fascinating new insights into living organisms. EMBLEM Technology Transfer GmbH (EMBLEM), the commercial entity of the European Molecular Biology Laboratory (EMBL), announced today that it has signed a licensing deal with technological leader Carl Zeiss to commercialize a new technology called SPIM (Se...

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Trans at Biology Products

Mouse Anti-Mouse Glutathione S-transferase M1 (GSTM1) Monoclonal Antibody, Unconjugated from Lifespan Biosciences

Description:Anti-GSTM1 Monoclonal Antibody Store vial at -20 C prior to opening. Aliquot contents and freeze at -20 C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. <b...
Company:Lifespan Biosciences

Glutathione-S-Transferase (GST) Colorimetric Assay Kit from Sigma-Aldrich

Description:Biochem/physiol Actions: Glutathione-S-transferases (GSTs) are a group of enzymes important in the detoxification of many xenobiotics in mammals. The enzymes protect cells against toxicants by conjugating the thiol group of the glutathione to electrophilic xenobiotics, and thereby defend cells against the mutagenic, carcinogenic, and toxic effects of the compounds. GST activity is presen...
Company:Sigma-Aldrich

S. cerevisiae Direct Transformation Kit from Wako Chemicals USA, Inc.

Description:This kit is designed for easy transformation of the budding yeast, Saccharoyces sp.. The protocol allows for successful transformation simply by mixing a plasmid DNA and the kit reagents with cultured yeast cells. No complicated steps, such as centrifugation or cell washing, are required. The kit is particularly well suited for high-throughput transformation of a large number of yeast strains gro...
Company:Wako Chemicals USA, Inc.

S. cerevisiae Direct Transformation Kit from Wako Chemicals USA, Inc.

Description:This kit is designed for easy transformation of the budding yeast, Saccharoyces sp.. The protocol allows for successful transformation simply by mixing a plasmid DNA and the kit reagents with cultured yeast cells. No complicated steps, such as centrifugation or cell washing, are required. The kit is particularly well suited for high-throughput transformation of a large number of yeast strains gro...
Company:Wako Chemicals USA, Inc.

GenomONE-Neo EX HVJ-E 4 vial(s) Transfection Reagents from Cosmo Bio Co., Ltd.

Description:HVJ (hemagglutinating virus of Japan, also named Sendai virus) Envelope VECTOR KIT is a tool for transfection of molecules by means of membrane fusion. Most efficient transfection are for siRNA (RNAi), Protein, Oligo, cDNA, Antibodies, Vector, and Biomolecule in vitro and in vivo. GenomONE-Neo EX has a high fusing capability in short period of time that benetif sensitive primary cells or tissues...
Company:Cosmo Bio Co., Ltd.

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Trans at Biology Technology

Assess the In Vivo Activation of Signal Transduction Pathways with PathDetect Reporting Systems

Assess the In Vivo Activation of Signal Transduction Pathways withPathDetect Stratagene Signal transduction is essential to many cellular processes, such asgrowth, differentiation, an...

Highest Transfection Efficiency of an Endotoxin-Sensitive Mammalian Cell Line

midiprep kit Stratagene EF plasmid midiprep kit, a kit based on anion exchange chromatography, magneticbeads, and cesium ch...

Control RT-PCR Primers for Human Gene Transcripts with Varying Abundance

Stratagene We introduce six pairs of control RT-PCR primers that are designed todetect specific human gene transcripts with various expression levels. Theseprimer sets provide insight into whether cDNA synthesis has been effective forall ab...

Highest Possible Transformation Efficiencies for High-Throughput Applications

Convenient, time-saving 96Pack Gold competent cells streamline transformation procedures Julie Bonnardel Ronda Allen Bruce Jerpseth Sean Banks...

Optimizing Transfection Conditions for Studying Signal Transduction Pathways

Optimizing Transfection Conditions for Studying Signal TransductionPathways in vivo reporting systems Stratagene Stratagenes PathDetect <font face="S...

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Trans at Biology Definition

Transport protein

to the opposite side of the protein. There are 3 types of transport proteins, <a href="/ ?q=/ Biology-Definiti...

Transmembrane receptor

of some subcellular compartments and <a href="/ ?q=/ Biology-Defin...

Transmembrane protein

in which it is embedded. Extraction of a transmembrane p...

Transformation

: resulting from the introduction, uptake and expression of foreign <a href="/ ?q=/ Biology-De...

Signal transduction

<a href="/ ?q=/ Biology-Definition/ C...

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Trans at Biology Dictionary

Untranslated RNA

; for example, the <a href="/ ?...

Untranslated region

translation</ ...

Transversion

orientation...

Transverse

ventral...

Trans-splicing

acting factor. That factor is an <a href="/ ?q=/ Biology-...

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Trans at Medicine News

Transdermal HRT not cardioprotective in postmenopausal women with CAD

Transdermal hormone replacement therapy (HRT) does not reduce the risk of cardiac events in postmenopausal women with existing coronary artery disease (CAD). In the PHASE trial (Papworth HRT Atherosclerosis Study), researchers randomized 255 postmenopausal women with angiographically proven coronary artery disease to receive either transdermal HRT--17-beta-estradiol with or without cy...

Transdermal HRT not cardioprotective in postmenopausal women with Coronary Artery Disease

Transdermal hormone replacement therapy (HRT) does not reduce the risk of cardiac events in postmenopausal women with existing coronary artery disease (CAD). In the PHASE trial (Papworth HRT Atherosclerosis Study), researchers randomized 255 postmenopausal women with angiographically proven coronary artery disease to receive either transdermal HRT--17-beta-estradiol with or without cy...

Infant receives first bloodless liver transplant

An Iowa infant aged 7 months was the first recipient of a bloodless liver transplant in Los Angeles, the United States of America. The seven month old, Aiden Michael Rush, whose parents are Jehovah’s Witnesses are prohibited by their religion to receive transfusions. The boy received 20% of his mother’s liver during the transplantation on February 7th at the children’s hospital i...

Liver donors can thrive after transplant

Contrary to belief that donating liver can injure the donor, it is now established without doubt that a living person can donate a part of his liver to a person needing it. And the good news is that the donor would continue to live well and thrive after donating part of his/her liver. Donation of a piece of the liver's right lobe from one adult to another is a relatively new procedure. I...

ATG useful in transplant patients as substitute for steroids

Anti-thymocyte globulin (ATG), a compound made from rabbit antibodies appears to be as effective as routine steroids in reducing rejection of transplanted organs without any of the side effects, according to Dr. James Eason of the Ochsner Multi-Organ Transplant Center in New Orleans. In the largest study on steroid-free treatment of liver transplants, Dr. Eason found patients treated with ATG had...

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Trans at Medicine Products

Transphenoidal Curettes

Description:10 overall length 4.5 from bend 250 mm. 90...
Company:Life Instrument Corporation

Translucent White-Long

Description:Designed to provide occlusion while permitting observation of the eye. Helpful to determine if only one eye is deviating. Approximately 9 inches long....
Company:Richmond Products, Inc.

Vista Transilluminator

Description:Keeler ophthalmoscopes are individually adjusted for perfect focus where it's needed - in the eye, not on paper. This, along with Keeler's wide angle light beam and infinity focus, ensures that whatever the patient's pupil size, you will see the clearest and largest field of view. Lithium-ion technology provides a longer life battery and fast charge capability....
Company:Keeler Instruments Inc.

2000 series revised ETDRS Translucent Charts

Description:These revised charts incorporate the slight change in the difficulty score for each of the 10 Sloan letters derived from the best corrected visual acuity examinations of 7420 eyes during the ETDRS study. The original charts difficulty scores were derived from the examination of 234 eyes. In addition to the revised arrangement of letters which resulted in the ultimate homogeneity of difficulty per...
Company:Precision Vision, Ltd.

Reduced 2000 series revised ETDRS Translucent Charts

Description:These revised charts incorporate the slight change in the difficulty score for each of the 10 Sloan letters derived from the best corrected visual acuity examinations of 7420 eyes during the ETDRS study. The original charts difficulty scores were derived from the examination of 234 eyes. In addition to the revised arrangement of letters which resulted in the ultimate homogeneity of difficulty per...
Company:Precision Vision, Ltd.

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Trans at Medicine Technology

TransPharma Medical Announces Positive Results of Phase I Clinical Trials for Transdermal Delivery of hPTH (1-34) for Osteoporosis Treatment

LOD, Israel--(BUSINESS WIRE)--Jul 9, 2007 - TransPharma MedicalLtd., a specialty pharmaceutical company focused on the developmentand commercialization of drug products utilizing a proprietaryactive transdermal drug delivery technology, announced todaypromising results of its phase I clinical trials demonstrating thesafety and pharmacokinetic profile of its ViaDerm-hPTH (1-34)product for th...

Velcade (bortezomib) for Injection Based Induction Therapy Delivered High Post-Transplant Complete Remission Rate, a Critical Marker for Increased Overall Survival

- New Data from Phase III Intergroupe Francophone du Myelome (IFM)Trial Presented During IMW - CAMBRIDGE, Mass., July 02, 2007 /PRNewswire-FirstCall/ --Millennium Pharmaceuticals, Inc. today reported that new data werepresented on the comparative Phase III clinical trial evaluating aVELCADE based therapy in newly diagnosed multiple myeloma (MM)patients. As induction therapy prior to stem...

A 4-Week Therapy with Transition Therapeutics' E1-I.N.T. Leads to Sustained Reductions in Blood Glucose Levels for 6 Months Post-treatment in Type 2 Diabetes Patients

Final Results from Exploratory Phase IIa Clinical Trial in Type 2Diabetes Patients Announced TORONTO, June 28, 2007 /PRNewswire-FirstCall/ - TransitionTherapeutics Inc. ("Transition") , today announces the results fromits exploratory Phase IIa clinical trial indicating that 4-weeks ofdaily treatments with gastrin-based therapy, E1-I.N.T.(TM), showedsustained reductions in blood glucose co...

AMIA Announces 2008 Summit on Translational Bioinformatics

Program to address a broad range of topics coveringresearch-related issues and best practices in bioinformatics andcomputational biology BETHESDA, Md., June 21, 2007 /PRNewswire-USNewswire/ -- TheAmerican Medical Informatics Association (AMIA) Board of Directors,in support of its strategic plan, has approved the development ofan annual meeting that will explore topics related to translati...

NuPathe Reports Positive Phase One Results for NP101 Transdermal Therapy for Acute Migraine

CONSHOHOCKEN, Pa.--(BUSINESS WIRE)--Jun 8, 2007 - NuPathe Inc., aprivately held specialty pharmaceutical company, today announcedpositive results from an initial Phase I study of NP101SmartRelief, a novel treatment for acute migraine being developedby NuPathe. NP101 combines NuPathe's SmartRelief(TM) proprietaryiontophoretic transdermal technology with sumatriptan, the mostwidely prescri...

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Trans at Medicine Definition

Newborn transport

without the specialist, intensive c...

Fat transfer

Overview of Current Fat Transfer Techn...

Atransferrinemia

<a href="/ ?q=/ Medicine-Definition/ Image:Violet_atransf.jp...
Trans at Medicine Dictionary

Transurethral resection of the prostate

impotence</ a...

Transplant rejection

. See also <a href="/ ?q=/ Medicine-Dictionary/ graft" class="hi...

Translocation

21, b...

Transillumination

<A href="http:/ / www.healthcentral.com/ ency/ 408/ 003389.html"target=...

Transient ischemic attacks

<A href="http:/ / www.mayoclinic.com/ health/ transient-ischemic-attack/ DS00220/ DSECTION=2"t...

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(Date:5/16/2008)... that Primary care medicine is in a precipitous de...merican College of Physicians (ACP), today joined...sumers to issue a call for comprehensive reforms t...nd other primary care physicians. , During a pa...ne in the U.S., Dr. Dale and other panelists spoke...
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Breaking Medicine News(10 mins):Health News:ACP says major system reforms needed to improve the state of primary care medicine in the US 2Health News:Homecare Workers Outraged by Proposed Cuts, Wage Reductions 2Health News:Everybody in the Club Scream O! 2Health News:Gene Signature May Predict Recurrence of Lung Cancer 2Health News:Gene Signature May Predict Recurrence of Lung Cancer 3
(Date:5/15/2008)...was divided into two separate groups within Africa...Aviv University mathematician. Climate change, red...e caused and maintained the separation. , Dr. S...ences at Tel Aviv University, worked with team lea...analyze African DNA. Their goal was to study obscu...
(Date:5/15/2008)..., 2008) Argonne National Laboratory has signed a ...ver National Laboratory (SRNL) to collaborate on n...h projects in support of critical U.S. Energy Depa...iorities. , "The MOU allows Argonne to remain a ...or Robert Rosner said. "Argonne has the nation,s l...
(Date:5/15/2008)...earchers Karen Staehling-Hampton, Ph.D., Managing ..., Ph.D., Investigator, collaborated with colleague...o cause spinal mutations in chick and mouse model ...nts with congenital vertebral abnormalities. , ...of the American Journal of Human Genetics. , Wo...
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Breaking Biology News(10 mins):Long lost sisters 2Argonne-SRNL agreement supports critical DOE, national priorities 2Stowers Institute researchers identify gene linked to vertebral defects in patient populations 2Adding up business and energy 2Gen Probe to Webcast Two Upcoming Investor Presentations 18865 1Gen Probe to Webcast Two Upcoming Investor Presentations 18865 2Alsius Corporation to Host First Quarter 2008 Financial Results Conference Call on May 15 2008 5248 1Alsius Corporation to Host First Quarter 2008 Financial Results Conference Call on May 15 2008 5248 2Noise in Artery Could Warn of Heart Risk 18863 1Noise in Artery Could Warn of Heart Risk 18863 2Raising the Bar on MonoPropyleneGlycol USP EP 18858 1Raising the Bar on MonoPropyleneGlycol USP EP 18858 2
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