Fibril Shape Is The Basis Of Prion Strains And Cross-species Prion Infection
New research on prions, the infectious proteins behind "mad cow" disease and Creutzfeld-Jakob disease in humans, suggests that the ability of prions in one species to infect other species depends on the shape of the toxic threadlike fibers produced by the prion. Two studies on the topic appear in the 8 April issue of the journal Cell. Although research suggests that prions from one specie...15 generations of untrained jocks, couch potatoes show big physiological adaptations
So, you don't like to exercise? Maybe you could blame it on your great-great-grandparents. Similarly, if you're a practiced and proud couch potato who suddenly woke up to the fact that you're a "natural" athlete, the credit could also belong to your genes. Exercise research traditionally has focused on the effects of training, rather than underlying genetic mechanisms. But physiologists wo...DNA constraints control structure of attached macromolecules
A new method for manipulating macromolecules has been developed by researchers at the University of Illinois at Urbana-Champaign. The technique uses double-stranded DNA to direct the behavior of other molecules. In previous DNA nanotechnology efforts, duplex DNA has been used as a static lattice to construct geometrical objects in three dimensions. Instead of manipulating DNA alone into s...Exercise training in ordinary people affects the activity of 500 genes
A new study from Karolinska Institutet in Stockholm shows that hundreds of genes in the thigh muscle are activated in regular cycle training. The study also reveals that great differences in training response may be due to the ability in some people to activate their genes much more forcefully. The study is published May 2 in FASEB Journal. It is common knowledge that it is very dangerous...Experimental vaccine protects lab animals against several strains of H5N1
Nations are preparing to stockpile vaccines against H5N1, the strain of influenza virus that experts fear could cause the next flu pandemic. But will these vaccines remain effective as the virus mutates? Researchers present good news in the July 15 issue of The Journal of Infectious Diseases, now available online. Elena Govorkova, MD, PhD, Robert G. Webster, PhD, and coworkers at St. Jude...EBY100 S. cerevisiae Strain from Invitrogen
Description:The pYD1 Yeast Display Vector is specifically designed to target and display recombinant proteins on the surface of Saccharomyces cerevisiae. Displayed proteins can be analyzed for their ability to interact with known or putative ligands. pYD1 uses the a-agglutinin yeast adhesion receptor which consists of two domains Aga1 and Aga2 to display recombinant protein on the surface of S. cerevisiae. T...Mechanical Cell Strain Instrument ST-160 Microscope Mountable from B-Bridge International
Description:Control and regulate cell stretching or compression of a single cell culture on a microscope stage. Computer controlled so you can precisely regulate the degree and frequency of the strain to produce 64 unique strain parameters. ST-160 has a narrower strain range then the ST-150. Both models are compatible with Nikon, Olympus, Leica, and Zeiss microscopes. ST-150 with 4 cm3 strain chamber...Mechanical Cell Strain Instrument STREX ST-195 Microscope Mountable from B-Bridge International
Description:The versatile ST-195 allows real-time observations of cell cultures under precise, controlled strain conditions. This instrument has 64 different strain parameters in addition to a microscope mountable CO2 incubator. The thin silicon strain chamber used by the ST-195 is compatible with inverted microscopes and fluorescence microscopy. ST-195 can be used with Nikon, Olympus, Leica, and Zeiss micro...Mechanical Cell Strain Instrument STREX ST-190-XY Microscope Mountable from B-Bridge International
Description:ST-190-XY is an automated instrument with a thin silicon strain chamber to observe cells in real-time using light or fluorescence microscopy. Biaxial strain that is experienced by endothelial, muscle, and fibroblast cells can be simulated by mechanical stretching or compression along the X and Y axis of our strain chamber. Strain can be applied simultaneously or independently along the X and Y ax...Using XL1-Red Mutator Strain to Generate Esterase Variants
XL1-Red cells allow isolation of gene productswith altered activity Markus M.Enzelberger Institute for Technical Biochemistry, University of Stuttgart, Stuttgart,Germany Institute for Industrial Genetics, University of...Electrophoretic Karyotypes of Wine Strains of Saccharomyces cerevisiae
Contributed by Alan T. Bakalinsky Department of Food Science and Technology, Oregon State University, Corvallis, OR 97331-6602 Chromosomal profiles of wine strains of Saccharomyces cerevisiae were compared to those of a standard laboratory karyotype. Qualitative analysis supported previous genetic...Visions: Matheys says CIO role is good training for executive suite
Provided t...African HIV strains more resistant to anti HIV drugs
Genetic variations in the HIV strains in Africa make it more difficult for the anti AIDS drugs to act on them according to researchers. This however does not mean that these drugs will be powerless against the virus but these drugs find it difficult to latch on to the protease, which is an enzyme useful in the replication of the virus inside the body. If the drug attaches itself to the p...E. coli strains resistant to a common antibiotic
Food contaminated with a strain of drug-resistant E. coli has emerged as a possible new source of urinary tract infections. E. coli is a normal inhabitant of the digestive tract that can cause both intestinal upsets and urinary infections. But while E. coli from bad food is a frequent cause of diarrhoea and other digestive miseries, urinary tract infections were thought until now to result mostly...Training with weights helps building resistance
According to researchers, many people have believed that training with free weights - dumb bells and bar bells is best kept for youthful people.// According to Bruce Craig, of the Human Performance Laboratory at Atlanta University, men and women well past retirement age have much to gain from resistance training. Weight work increases your mobility and improves reaction time - both of w...Hormone restrains appetite in man
According to reasearchers, a hormone is released into the blood after a meal, restrain the appetite if given by injection and might be supportive in treating obesity. The reason for feeling full after a meal, that the intestines release a hormone called PYY3-36 //which acts on the brain to produce a feeling of satiety. Researchers at Imperial College, London, now report on the first human trial...Influenza Avian Flu strain has become more contagious and dangerous.
The Influenza avian flu strain - H5N1 has mutated since 2002 to become more dangerous //and increases the risk of causing a pandemic disease. The Asian strain H5N1 influenza virus has changed its characters since 2002, as the virus has become less deadly to ducks; the virus multiplies in the ducks without infecting them but spreads and infects other birds and humans. The duck Waterfowl...Ascent Primary Knee System - Ascent posterior stabilized/constrainable open box femoral components.
Description:Cruciate retaining, posterior stabilized and constrained components....NexGen Complete Knee Solution Legacy Knee Constrained Condylar Knee (LCCK)
Description:The NexGen Legacy LCCK Femoral Component is intended for patients who require additional prosthetic stabilization due to inadequate mediolateral, anteroposterior and varus/valgus ligament function, and require augmentation and/or stem extensions due to inadequate bone stock. The NexGen LCCK is available with a non-coated fixation surface. This device is for cemented use only....New Flu Vaccine from PepTcell Could Provide Immunity Against All Strains of Influenza Virus
HIGH WYCOMBE, UK 18th June 2007-Previously undisclosedpre-clinical data showing how a new flu vaccine has the potentialto protect against all strains of influenza, including pandemic andannual, was presented today by PepTcell, at the 2007 Options forthe Control of Influenza VI (Options) Conference, in Toronto,Canada. The pre-cli...New Flu Vaccine From PepTcell Could Provide Immunity Against All Strains of Influenza Virus
Data Presented at Leading Influenza Conference HIGH WYCOMBE, England, June 18, 2007 /PRNewswire/ -- Previouslyundisclosed pre-clinical data showing how a new flu vaccine has thepotential to protect against all strains of influenza, includingpandemic and annual, was presented today by PepTcell, at the 2007Options for the Control of Influenza VI (Options) Conference, inToronto, Canada....