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Trafficking in Medical News

Regulation and oversight of gun sales reduces trafficking to criminals

Comprehensive regulation of gun sellers appears to reduce the trafficking of guns to criminals, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health. Preventing the diversion of guns to criminals is important because 85 percent of guns recovered by police ...

American Legion, Department of Indiana Releases Statement Concerning Revelations of Illicit Drug Trafficking at Roudebush VA Medical Center

INDIANAPOLIS, Dec. 4 /PRNewswire-USNewswire/ -- The Commander of The American Legion Department of Indiana has released the following statement concerning illegal drug trafficking at Indianapolis' Roudebush VA Medical Center: "The men and women of The American Legion Department of Indiana...

Commentary in The Lancet on the Declaration of Istanbul Sees Organ Transplantation Worldwide Threatened by Organ Trafficking and Transplant Tourism and Commercialism

BOSTON, Massachusetts, July 3 /PRNewswire/ -- The July 5 issue of the leading medical journal, The Lancet, highlights the Declaration of Istanbul on Organ Trafficking and Transplant Tourism, an important affirmation of ethical principles and practices adopted on May 2, 2008, at an Internationa...

AVMA Urges Outlawing Trafficking of Chimps, Monkeys and Nonhuman Primates and Pets

SCHAUMBURG, Ill., March 11 /PRNewswire-USNewswire/ -- Citing concerns about the spread of disease and injury, inhumane treatment of animals, and ecological damage, Dr. Gail Golab, PhD, DVM, director of the American Veterinary Medical Association (AVMA) Animal Welfare Division, spoke on the dan...

Protein-dependent 'switch' regulates intracellular trafficking in epithelial cells

NEW YORK (Dec. 10, 2007) -- With findings highlighted on a recent cover of Developmental Cell, researchers at Weill Cornell Medical College in New York City have shed important new light on key trafficking mechanisms within epithelial cells. Epithelial cells line the outside of nearly all organs. ...

Report Finds That Raids Are Not an Effective Tool Against Human Trafficking

Calls on Obama and Biden to Develop Alternative Approaches NEW YORK, Jan. 9 /PRNewswire-USNewswire/ -- A new report concludes that so-called "rescue" raids are not an effective way to stop trafficking in persons and in fact can be counter-productive. The report from the Sex Workers Proj...

Transplant experts convene at ASN Renal Week 2008 to discuss organ trafficking

With the number of patients in need of organ transplants on the rise, an increasing number of patients are turning to unconventional sources for organs. Individuals are willing to donate their kidneys for financial incentive, particularly in developing countries where the poverty rate is high, res...

Human Trafficking Booming in Eastern Europe, but Governments Dont Seem to Care

Soviet Union has fallen, there is no way communism can be restored again, the new ruling elite gloat in countries that were once part of that setup. But poverty, prostitution and crime thrive like never before in that region. Young girls are the worst victims of the churning. On a per ca...

Illegal Drug Trafficking Pose A Great Threat For HIV Epidemic In Northeast

Heroin and synthetic pharmaceuticals illegally trafficked from Myanmar into India's northeast has led to a rise in drug abuse and an HIV epidemic in the region// , says a United Nations study. "Drug trafficking across the common border of Myanmar and the northeastern state of Manipur, Mizoram ...

Travel And Tourism Industry Calls For Global Efforts To Limit Sexual Trafficking Of Children

An international conference, 'United Front for Children: Global Efforts to Combat Sexual Trafficking of Children in Travel and Tourism' // to be held on the 21st of April at the University of Minnesota will focus on ways and means to curb sex trafficking, at a global level. The event to be held at ...

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Trafficking in Medical Technology

DNA Helps Reunite Children With Their Families

... are under 17. It is estimated that by 2010, human trafficking will be the No. 1 crime worldwide. Arthu...manitarian effort using DNA testing to deter human trafficking of children and help reunite abducted and homeless...ll be obtained from children associated with human trafficking whether through prostitution, forced labor, milita...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

...idney failure and increased risk of heart attack and stroke. Amigal is designed to selectively bind to and stabilize a-Gal A, which facilitates proper trafficking of the enzyme to the lysosomes, where it is needed to break down GL-3. Fabry disease is estimated to affect approximately 5,000 to 10,000 people...

PROTECT-1 Phase II/III Induction-Stage Results for ChemoCentryx's Traficet-EN(TM) Presented in Oral Session at DDW 2009 Conference

...the CCR9 chemokine receptor. In adults, CCR9 is a highly specific receptor expressed by T cells that migrate selectively to the digestive tract. The trafficking of T cells to the small and large intestine causes persistent inflammation that may result in Crohn's disease or ulcerative colitis - the two principa...

Amicus Therapeutics Announces Successful Completion of End of Phase 2 Meeting With FDA for Amigal in Fabry Disease

...ing to the misfolded enzyme responsible for Fabry disease, alpha-GAL. After binding to the enzyme, Amigal promotes the proper folding, processing, and trafficking of the enzyme from the endoplasmic reticulum to its final destination, the lysosome, the area of the cell where the enzyme does its work. Once it reac...

Amicus Therapeutics Announces Positive Results From Two Phase 1 Clinical Studies of AT2220 for Pompe Disease

...to lysosomal accumulation of glycogen inside muscle cells, which is believed to cause the various symptoms of Pompe disease. AT2220 facilitates proper trafficking of the enzyme to the lysosomes, the compartments in the cell where it is needed to break down glycogen. AT2220 has been shown to increase GAA levels i...

CellCyte Genetics Corp. Enters Collaborative Research Agreement With Cleveland Clinic Foundation to Qualify Stem Cell Delivery in Damaged Heart Tissue

...ic Foundation of Cleveland, Ohio. The goal of the collaboration is to investigate the presence and regulation of heart receptors involved in stem cell trafficking in normal and diseased human hearts, using CellCyte's proprietary compounds. CellCyte Genetics is developing stem cell enabling therapeutic products ...

EntreMed Presents Data for Phase 2 Study of MKC-1 in Metastatic Breast Cancer

...y, binding importin-b and tubulin, cell cycle arrest, and apoptosis. MKC-1 arrests mitosis by inhibiting an intracellular target important in cellular trafficking that has been shown to be involved in cell division. MKC- 1 has been shown to inhibit mitotic spindle formation, prevent chromosome segregation in the...

Amicus Therapeutics Presents Data From Preclinical and Phase 1 Studies of Amigal for Fabry Disease

.... This deficiency leads to lysosomal accumulation of GL-3, which is believed to cause the various symptoms of Fabry disease. Amigal facilitates proper trafficking of the enzyme to the lysosomes, the compartments in the cell where it is needed to break down GL-3. At the ACMG meeting, Amicus scientists will p...

Amicus Therapeutics Presents Preclinical Data from Studies of Plicera for Gaucher Disease

... accumulation of glucocerebroside inside certain cells, which is believed to cause the various symptoms of Gaucher disease. Plicera facilitates proper trafficking of the enzyme to the lysosomes, the compartments in the cell where it is needed to break down glucocerebroside. The following is a summary of the...

Amicus Therapeutics Presents Positive Results From Phase 1 Clinical Studies of Plicera for Gaucher Disease

... accumulation of glucocerebroside inside certain cells, which is believed to cause the various symptoms of Gaucher disease. Plicera facilitates proper trafficking of the enzyme to the lysosomes, the compartments in the cell where it is needed to break down glucocerebroside. Phase 1 Plicera data being presen...
Trafficking in Medical Definition

Thymocyte

...ive tendencies in the thymus. “J Immunol.” 173:6515-20, 2004. http://www.jimmunol.org/cgi/content/full/173/11/6515 ] ^ Schwarz BA, Bhandoola A. trafficking from the bone marrow to the thymus: a prerequisite for thymopoiesis. Immunol Rev 209:47, 2006. full text ^ Schwarz BA, Sambandam A, Maillard...
Trafficking in Medical Dictionary

Vesicle

...ame vesicle tends to contain all ... ... play roles in both vesicle trafficking and in regulating actin ... A role for phosphatidylinositol transfer protein in secretory vesicle formation. ... Although the vesicle trafficking protein VAMP-2 only partially overlapped with ... Insulin signaling: GLUT...

LSD

...e who take it to witness illusions. It also alters their thought... LSD is a Schedule I substance under the Controlled Substances Act. ... LSD trafficking and abuse have decreased sharply since 2000, and a resurgence ... LSD use among high school students is a particular concern. ... Some LSD ...
Trafficking in Biological News

Weill Cornell Research Reveals Secrets Of Trafficking Within Cells

As you read this, cells in your eye are transmitting information to your brain, while cells in your heart and arteries work just as hard to keep that brain alive. Every one of these cells -- and others throughout the body -- depends on an internal process called endocytosis to keep the flow of cell...

Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease

...tional. "We know who folds them up, but our big question is: Who takes them over there? It could be that chaperones and helpers both are important for trafficking receptors. If we can inhibit the trafficking, we can inhibit the hormone response." Hsp90, is one of the most common of the ubiquitous heat shock ...

Fate in fly sensory organ precursor cells could explain human immune disorder

...ta vesicles to the apical region of the daughter cells. If this complicated trafficking of Delta does not occur, the ability of Delta to activate Notch is compromi...the Arp2/3 complex. In our work we found that WASp is also required for the trafficking of Delta to the top of the actin structure," said Bellen. Notch signal...

Advance in understanding cellulose synthesis

...omplexes go as they build the cell wall, but microtubules also organize the trafficking and delivery of the cellulose synthase complexes to their place of action. They also looked at the role in trafficking of a structural element called the actin cytoskeleton that helps move organ...

Tulsa County Sheriff Selects BIO-key(R) Mobile Data System

...way to communicate with each other in mutual aid situations. The Sheriff's Office expects that this will help in the fight against narcotics and human trafficking along the I-44 corridor, which traverses Tulsa County and links the southern U.S. border with the Midwest. "MobileCop lets us share critical informati...

DNA-Prokids: Genetic identification against traffic in human beings

...a-prokids.org ), an international project on human trafficking prevention and fight using genetic identification ...roximately two million people are victims of human trafficking across the world. UN Secretary-General, Ban Ki-Moo...as a programme for genetic identification of human trafficking victims and their relatives, serves "a triple obje...

Tulsa County Sheriff Selects BIO-key(R) Mobile Data System

...way to communicate with each other in mutual aid situations. The Sheriff's Office expects that this will help in the fight against narcotics and human trafficking along the I-44 corridor, which traverses Tulsa County and links the southern U.S. border with the Midwest. "MobileCop lets us share critical informati...

CSHL researchers identify gene that helps plant cells keep communication channels open

...mata," says Jackson, whose lab at CSHL is devoted to the study of plant genetics. "Our study suggests a mechanism through which plant cells can adjust trafficking in these channels through the various stages of development." The team's findings will be published in the Feb 17th issue of Proceedings of the Natio...

New insights into a leading poultry disease and its risks to human health

...sited into a public gene database. Among the disease causing parts of the plasmid pAPEC-1 are a series of genes that make up proteins responsible for trafficking nutrients in and out of bacteria, called ABC transporters, which may be used to develop vaccine candidates. In addition to nutrition, many other ABC t...

Fluorescent proteins illuminating biomedical research

...eins, called fluorescent timers (FTs), can change their color from blue to red over a matter of hours. "These FTs will enable scientists to study the trafficking of cellular proteins and to provide accurate insight into the timing of intracellular processes, such as activation or inhibition of gene expression o...
Trafficking in Biological Technology

AST Endorses Istanbul Declaration to End Organ Trafficking and Transplant Tourism

American Society of Transplantation Admonishes Citizens of Rich Nations To End Reliance on Donors in Less Affluent Nations MT. LAUREL, N.J., Aug. 19 /PRNewswire/ -- The American Society of Transplantation (AST) endorses The Declaration of Istanbul on Organ Trafficking and Transplant ...

Novel drug discovery tool could identify promising new therapies for Parkinson's disease

...termined why the cyclic peptides are protective. They found that the cyclic peptides do not affect a system of transport inside cells known as vesicle trafficking which was a surprise, since alpha-synuclein and other proteins that have been implicated in human Parkinson's disease are believed to play a role in ...

Celsense, Inc Receives NIH Grant to Translate Cell Imaging Technology for Clinical Use

... NIH funds human clinical testing of the cell trafficking MRI reagent, Cell Sense. Pittsburgh, PA (Vocus) ... Company involve proprietary imaging agents that can be used to observe the trafficking of cells using magnetic resonance techniques. Celsense’s mission is t...

ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week

...the CCR9 chemokine receptor. In adults, CCR9 is a highly specific receptor expressed by T cells that migrate selectively to the digestive tract. The trafficking of T cells to the small and large intestine causes persistent inflammation that may result in Crohn's disease or ulcerative colitis - the two principa...

Researchers develop new way to see single RNA molecules inside living cells

...ategy to study how single viral RNAs travel from the nucleus of a cell to a virus assembly site, how mRNAs are regulated by location and time, and RNA trafficking in neurons," added Santangelo. ...

Amicus Therapeutics Presents Positive Results From Phase 2 Extension Study of Amigal(TM) for Fabry Disease at ACMG 2009 Annual Meeting

...idney failure and increased risk of heart attack and stroke. Amigal is designed to selectively bind to and stabilize a-Gal A, which facilitates proper trafficking of the enzyme to the lysosomes, where it is needed to break down GL-3. Fabry disease is estimated to affect approximately 5,000 to 10,000 people...

Cordex Pharma Presents 'New Frontiers in Cardiovascular Medicines' on January 29

...fication. The ramifications of his work extend to all major classes of proteins: ion channels, receptors, G proteins, transcription factors, membrane trafficking proteins and numerous enzymes that are now known to be regulated by S-nitrosylation. Accumulating evidence suggests that many disease states are asso...

MedImmune Presents Data Highlighting its Progressive Inflammatory Disease Portfolio at the 72nd Annual Meeting of the American College of Rheumatology

...ain - Brandon Higgs, Ph.D., Sunday, October 26 from 9:00 a.m. - 11:00 a.m. in Hall A, Abstract: 35 -- Neutralization of CXCL13 impacts B-cell trafficking and reduces severity of established experimental arthritis - Matthew Sleeman, Ph.D., Monday, October 27 from 9:00 a.m. - 11:00 a.m. in Hall ...

SENOMYX CO-FOUNDER AND SCIENTIFIC ADVISORY BOARD MEMBER ROGER TSIEN, PH.D., AWARDED NOBEL PRIZE IN CHEMISTRY

... GFP and other members of the GFP family. The originally isolated GFP protein provided a way to mark cells expressing specific genes and to follow the trafficking of proteins within cells. Work performed in Dr. Tsien's UC San Diego laboratory determined the mechanism by which GFP exhibits its green color and led...

Abeome Forms First Class Scientific Advisory Board

... Associate Director of the Life Sciences Institute at the University of British Columbia, has a distinguished research career focused on intracellular trafficking and cell signaling of specific membrane receptors on the cell surface of B lymphocytes, the source of antibody production. "We are pleased to assemb...
Trafficking in Biological Products

QXL 520 C2 maleimide from AnaSpec

Description:...574 nm. Solvent System: DMF or DMSO. References: Evans NA, et al. (2001). Visualizing differences in ligand-induced beta-arrestin-GFP interactions and trafficking between three recently characterized G protein-coupled receptors. J Neurochem 77, 476-85; Nasarabadi S, et al. (1999). Simultaneous detection of TaqMa...
Company:AnaSpec

jetSI-ENDO-FluoF from Polyplus Transfection

Description:...he powerful siRNA transfection reagent. These reagents are used to determine the transfection efficiency or investigate the intracellular delivery and trafficking of siRNAs. More than 95 % of the cell population is transfected....
Company:Polyplus Transfection

jetSI-ENDO-FluoR from Polyplus Transfection

Description:...he powerful siRNA transfection reagent. These reagents are used to determine the transfection efficiency or investigate the intracellular delivery and trafficking of siRNAs. More than 95 % of the cell population is transfected....
Company:Polyplus Transfection
Trafficking in Biological Definition

Cell membrane

...demy of Sciences, Series of Biology , 12, No 5, 1986, pp. 347-352 (In Russian, English summary) External links Lipids, Membranes and Vesicle trafficking - The Virtual Library of Biochemistry and Cell Biology ...

Lipid

...yers form the foundation of all biological membranes . See also Biochemistry Fat External links Lipids, Membranes and Vesicle trafficking - The Virtual Library of Biochemistry and Cell Biology IUPAC glossary entry for the lipid class of molecules what is IUPAC? ...

Cell membrane

...demy of Sciences, Series of Biology , 12, No 5, 1986, pp. 347-352 (In Russian, English summary) External links Lipids, Membranes and Vesicle trafficking - The Virtual Library of Biochemistry and Cell Biology ...

Vesicle

...oat clusters selected membrane cargo proteins into nascent vesicle buds. See also: micelle External links Lipids, Membranes and Vesicle trafficking - The Virtual Library of Biochemistry and Cell Biology ...
Trafficking in Biological Dictionary

Mitochondrial membrane

...e organelle, has about ... The inner mitochondrial membrane contains more than 100 different polypeptides, ... general principles of membrane trafficking that may be. applicable to mitochondrial fusion. ... 4. General considerations of mitochondrial membrane . fusion ... Mitochondrial Membran...

Leucocyte

...on. Causes (1 conditions) Misdiagnosis ... Online Shopping at DirectTextBook.com - Save up to 80%, buy or rent. New and used books like Leucocyte trafficking Role of Fucosyltransferases and Selectins Ernst... Zoology information, history, articles and research from Academic Journals, Newspapers, and maga...

Chaperone Proteins

... Proteins Hsp70 and BiP Fold and Traffic Islet Amyloid Polypeptide in ... common polymorphisms in these chaperone proteins on IAPP folding and trafficking ... ...

Cell nucleus

.... The nucleus is a membrane bound structure that contains the cell's hereditary ... The motion of RNA and proteins in the cell nucleus . trafficking as a means of targeting ... The mammalian cell nucleus contains a large number of non-random ... The largest and most clearly visible of the c...
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