FluoroPharma to Present Phase I Study Results of Novel Positron Emission Tomography (PET) Myocardial Perfusion Imaging (MPI) Tracer

BOSTON, June 15 /PRNewswire/ -- FluoroPharma Inc., a company developing breakthrough PET molecular imaging agents, announced that it will present Phase I data relating to the safety, dosimetry, and pharmacokinetics in human subjects of BFPET, its novel 18-F labeled PET tracer for myocardial perfus...

Chest Pain Can Be Identified By New Tracer Chemical 30 Hours After Pain Relief

Nuclear medicine combines computers, detectors and radioactive substances called radioisotopes to produce images of blood flow and biochemical functions in the heart and other organs//. What makes the procedure so valuable is that it is possible to obtain the required information without disturbing...

Brookhaven Lab and Hybridyne Imaging Technologies Inc., win R&D 100 award

...e new cadmium zinc telluride (CZT)-based gamma camera is small enough for trans-rectal prostate cancer diagnosis, after the patient is injected with a tracer radiopharmaceutical. The high-resolution CZT detector is the cutting-edge technology that drives the novel system. Using this new technology, the work...

MDS Nordion Begins to Manufacture Cardiac Imaging Agent

...ved by the FDA, produces Rubidium-82, using a specialized generator technology. Once administered to the patient, Rubidium-82 is used as a PET imaging tracer for perfusion studies of the heart to examine blood flow through heart vessels. PET is a highly sensitive medical imaging technique that produces a th...

DFG establishes nine new collaborative research centers

...ransport, will also be addressed. Furthermore, the representation of cytobiological signals will be used for assessing the aggressiveness of a tumour. tracer and optical methods will then aid in transferring the molecular imaging from animal experiments to the clinical situation. (Host university: Technical...

New technique may help detect potential breast cancer spread

...oped Lymphoseek, compared the molecule's ability to detect nearby sentinel lymph nodes to that of the standard method using blue dye and a radioactive tracer substance. In the trial, the Moores Cancer Center team, which also examined the technique separately in melanoma patients, looked at 46 early stage...

Ongoing worldwide shortage of medical isotopes could threaten patient care, says expert

... means for producing medical radionuclides for the benefit of patients who desperately need them." Technetium-99m (Tc-99m) is used as a radioactive tracer in nuclear medicine investigations such as gamma cameras, which allow doctors to see inside a patient's body to track down damaged organs and tissues ...

McGill, MUHC and Douglas researchers get top marks from Quebec Science magazine

...ut for their discovery of Earth's oldest rocks, found in the Nuvvuagittuq greenstone belt located in Northern Quebec. The researchers used an isotopic tracer to obtain an age of 4.28 billion years for an unusual amphibolite comprised in the belt, making it 250 million years more ancient than any previously ...

Molecular marker identifies normal stem cells as intestinal tumor source

...that enabled them to selectively turn on a colored tracer molecule only in cells that were expressing, or had expressed, Prominin1. These tracer experiments revealed that Prominin1 cells generate...inin1 intestinal stem cells and used a fluorescent tracer to follow the offspring of these cells. Those stud...

Latest Breast Imaging Techniques Offer New Views

...he use of radiotracers to detect cancer cells. The tracer used in BSGI is positively charged, while cancer cells are negatively charged, so the tracer diffuses around the cancer cells and highlights th...er cells use more energy, they take up more of the tracer and are highlighted on the image. "I think it's...

Tracer in Medical Technology

FluoroPharma Announces Positive Phase I Safety Results for BFPET(TM), Myocardial Perfusion Imaging (MPI) Tracer for Positron Emission Tomography (PET)

BOSTON, July 23 /PRNewswire/ -- FluoroPharma Inc., a company developing breakthrough molecular imaging agents for the Positron Emission Tomography (PET) market, announced positive Phase I results for BFPET, its novel Fluorine-18 labeled tracer for myocardial perfusion imaging. BFPET is FluoroP...

FluoroPharma Announces Commencement of Phase I Clinical Trial for BFPET(TM), Myocardial Perfusion Imaging (MPI) Tracer for Positron Emission Tomography (PET)

BOSTON, March 19 /PRNewswire/ -- FluoroPharma Inc., a company developing breakthrough cardiovascular molecular imaging agents for the Positron Emission Tomography (PET) market, announced commencement of Phase I clinical trials for BFPET, following institutional review board (IRB) approval of t...

FluoroPharma Announces Positive Phase I Safety Results for CardioPET(TM), Coronary Artery Disease (CAD) Imaging Tracer for Positron Emission Tomography (PET)

BOSTON, March 3 /PRNewswire/ -- FluoroPharma Inc., a company developing breakthrough cardiovascular molecular imaging agents for the Positron Emission Tomography (PET) market, announced positive Phase I safety results for CardioPET, the company's lead product. The trial was designed to evalu...

Molecular Marker Identifies Normal Stem Cells as Intestinal Tumor Source

...that enabled them to selectively turn on a colored tracer molecule only in cells that were expressing, or had expressed, Prominin1. These tracer experiments revealed that Prominin1 cells generate...inin1 intestinal stem cells and used a fluorescent tracer to follow the offspring of these cells. Those stud...

New Breast Imaging Technology Targets Hard-to-Detect Cancers

... low-dose nuclear material called a radiotracer, which is absorbed by the cells. Because cancerous cells have a higher rate of metabolic activity, the tracer is taken up by these cells at a higher level than in normal cells. Dr. Brem and colleagues reviewed the records of 159 women with at least one...

FluoroPharma, Inc. to Report Preclinical Data on Alzheimer's Disease and Prostate Cancer PET Imaging Agents

...ew therapeutics." The second study, "Accumulation Of F-18 Labeled Modified Fatty Acid (CardioPET) In Prostate Tumor Cells: A Potential Sensitive Pet tracer For Prostate Imaging" explores the potential of CardioPET, a fatty acid analog, to detect prostate cancer. CardioPET concentrates in significant amoun...

Are PET Scans Beneficial During Cancer Diagnosis, Staging and Monitoring?

... a computer-based, low-resolution imaging technology emitting a radioactive tracer to localize tumors. The radioactive positron tracer gathers in abnormal tissue. As a result, the malignant tissue stands out fr...

Phase II Data on Lilly's Antibody Show It Affects Amyloid Beta, a Protein Believed To Be Associated with Alzheimer's Disease

...al fluid examinations. A sub-study of 24 patients and 13 volunteers underwent single photon emission tomography (SPECT) scanning using an experimental tracer to assess levels of amyloid beta plaque in the brain. The interim analysis showed that weekly infusions of LY2062430 up to 400mg per dose was well t...

Diverse Approaches to Alzheimer's Therapies Continue to Show Progress at ICAD

...e brain and spinal cord). In an optional sub-study, 24 Alzheimer's patients and 13 volunteers underwent a type of brain imaging known as SPECT using a tracer (known as IMPY) that measures the amount of amyloid plaque present in the brain. Measures of symptom severity were obtained in all AD patients using t...

Markers in Blood and Spinal Fluid, and a New Imaging Agent, Show Promise for Early Detection of Alzheimer's

... people using positron emission tomography (PET) scanners. With PET, a radioactive compound, or tracer, is injected into the person to be scanned. The tracer attaches to a target substance in the body, in this case amyloid, which then "lights up" on the image captured by the scanner. In research reported ...

Tracer in Medical Products

Cortisol EIA Kit

Description:... contains AChE tracer, antiserum, standard, Ellman's reagent, EIA buffer, wash buffer, Tween 20, plates pre-coated with anti-rabbit IgG, antiserum and tracer dyes, plate cover, and complete instructions....
Company:Cayman Chemical

MRI Compatible Syringe Pump

Features:... Ideal for drug delivery and tracer studies, MRI imaging. Easy to Use - A bright, easy to read, two-line fluorescent display can be easily read from across the lab. High Pressure ...
Company:Harvard Apparatus

Tracer in Medical Definition

Nuclear medicine

...the body; this is commonly known as a tracer. In the presence of disease, a tracer will often be distributed around the body and/or processed differently. For...e exclusion of a tracer, resulting in the appearance of a 'cold-spot'. Many tracer complexes have been developed in order to image or treat many different or...

Tracer in Medical Dictionary

Thyroid scan

... cancer. A thyroid scan uses a radioactive tracer and a special camera to measure how much tracer is absorbed from the bloodstream by the thyroid ...edicine examination that uses a radioactive iodine tracer to see how well the thyroid ... ... causes, ...

Gallium scan

... A gallium scan or gallium 67 scan is a type of nuclear medicine study that uses a radioactive tracer to obtain images of a specific type of tissue, or disease state of tissue. Gallium salts like gallium citrate and gallium nitrate are used. Th...

Tracer in Biological News

August 2009 Geology and GSA Today media highlights

...ecific interest here, iron isotopes in sediment pore fluids may be a unique tracer of bacterial processes that contribute to the input of iron to seawater; an...s, highlighting the potential for future research to use iron isotopes as a tracer of shelf-derived iron inputs to seawater. The findings will also aid future...

Extraterrestrial platinum was 'stirred' into the Earth

...m isotopes are widely used as tracers of mantle processes, but there has been a mismatch between signals from osmium and from other important isotopic tracer systems which has eluded explanation until now. Co-authors Dr Marco Fiorentini and Dr Wolfgang Maier from the University of Western Australia are de...

Iron isotopes as a tool in oceanography

...al processes can leave behind characteristic isotopic 'fingerprints'. Of specific interest here, iron isotopes in sediment pore fluids may be a unique tracer of sediment respiration by dissimilatory iron-reducing bacteria. Dissimilatory iron reduction is thought to be one of the earliest metabolic pathw...

DOE-funded research projects win 46 R&D 100 Awards for 2009

...ivermore National Lab National Energy Technology Laboratory (Pittsburgh, Pa. and Morgantown, WV ) http://fossil.energy.gov SEQURETM tracer Technology - uses perfluorocarbon tracers for ultra-sensitive detection of carbon dioxide leakage from geologic storage reservoirs. Clay-Liquid Ca...

Clinical trial shows quadriplegics can operate powered wheelchair with tongue drive system

...d Chih-wen Cheng attached a small magnet -- the size of a grain of rice -- to the participant's tongue with tissue adhesive. Movement of this magnetic tracer was detected by an array of magnetic field sensors mounted on wireless headphones worn by the subject. The sensor output signals were wirelessly trans...

'Chemical equator' discovery will aid pollution mapping

...air quality on either side of the chemical equator, which was 50 km wide and well to the north of the ITCZ. The study revealed that carbon monoxide, a tracer of combustion, increased from 40 parts per billion to the south, to 160 parts per billion in the north. The difference in pollutant levels was increas...

AGU Journal Highlights -- March 19, 2008

...SF 5 CF 3 can replace SF 6 in ocean injection experiments and preserving SF 6 as an ocean circulation tracer. Title: Use of SF 5 CF 3 for ocean tracer release experiments Authors: David T. Ho and William M. Smethie, Jr.: Lamont-Doherty Earth Observatory of Columbia University, Palisades, New York,...

Small streams mitigate human influence on coastal ecosystems

...ditions in 72 streams across multiple land use conditions (e.g., urban, agricultural, natural conditions) in the continental U.S. and Puerto Rico. The tracer let scientists measure how far the nitrate traveled and what processes removed it from the water. At low-to-moderate addition levels, streams were eff...

AGU journal highlights -- Feb. 26, 2008

...e that although sodium atoms compose only a small fraction of the atoms sputtered from the surface, the bright emission from the sodium can serve as a tracer for other constituents invisible to ground-based observers. Title: Imaging the sources and full extent of the sodium tail of the planet Mercury ...

Tiny dust particles from Asian deserts common over western United States

... San Francisco. For the dust detected at ground stations in the United States, Fischer also looked for and found evidence of calcium, which is a tracer for desert dust. "The calcium lends more confidence to our conclusion," she said. While the results of the research are not unexpected, they p...

Tracer in Biological Technology

Celsense, Inc Receives NIH Grant to Translate Cell Imaging Technology for Clinical Use

... critical bottlenecks in the development and delivery of cancer immunotherapies. About Cell Sense Cell Sense (patent-pending) is a fluorocarbon tracer agent used to safely and efficiently label cells ex vivo without the use of transfection agents. Labeled cells are transplanted into the patient enabl...

VIA Pharmaceuticals Announces Complete Enrollment in FDG-PET Phase 2 Study of VIA-2291 in Cardiovascular Patients

...d, placebo-controlled study examines the impact of VIA-2291 on plaque inflammation as measured by Positron Emission Tomography with fluorodeoxyglucose tracer (FDG-PET), as well as other standard biomarkers of inflammation, over 24 weeks following such an acute event. A total of 52 patients have been enrolle...

Thought Leaders Discuss Positive Outlook for Bapineuzumab in Alzheimer's Disease in MedPredict Report

...cert with approvals of agents that alter the course of the disease," continued Dr. Berk. "Our panelists are most excited about amyloid imaging using a tracer chemical called PIB." Companies mentioned in this report: GE Healthcare, Avid, Bayer Schering, Siemens, C2N Diagnostics, Satoris, Novartis, Forest, ...

Celadrin(R) Research Unveiled at Nutrigenomics 2008 Meeting in Paris, France

...of oral consumption. In Paris, Dr. Hesslink presented research from radio tracer label data and ligand binding assays supporting the hypothesis that Celadri...tory cascade. To support this hypothesis, Dr. Hesslink presented dual-label tracer data from the laboratory of Dr. Daniel Gallaher at the University of Minnes...

Berkeley scientists bring MRI/NMR to microreactors

... This is the first time hyperpolarized gas has been used to directly study catalytic reaction products on such a small scale and without the use of tracer particles or gas, says Bouchard. It opens the door for future studies of heterogeneous catalysis in which all the unique benefits of MRI, such as velo...

Measurement of Green Fluorescent Protein in the SpectraMax Gemini XS Spectrofluorometer (MaxLine Application Note #44)

... generate a highly visible fluorescence that requires no additional substrates has made it valuable as a marker for gene expression, as a cell lineage tracer or as an in vivo covalently attached fluorescent label replacing more invasive and unwieldy fluorescent staining techniques. GFP can be monitored no...

cAMP DataFile: Homogenous Cyclic AMP detection using High Efficiency Fluorescence Polarization

...es. In the absence of analyte, a maximal amount of tracer will be bound to the antibody. Addition of analyte competes with the tracer for the limited binding sites, so that the extent ...cer-antibody complex rotates more slowly than free tracer so that the fluorescence appears polarized. Displa...

TKXtra DataFile: Homogenous tyrosine kinase detection using High Efficiency Fluorescence Polarization

... Assay Conditions Samples containing phosphopeptides produced by the tyrosine kinase assay are mixed with fluorescein-labeled tracer and anti-phosphotyrosine antibody. The samples are incubated at ambient temperature and analyzed after 30 minutes with the same performance, using any...

Coated Plate Immunoassay on the MicroBeta - eg. TSH - IRMA

... ml anti-TSH. ASSAY PROCEDURE 1. Add 100 μL standard and samples in duplicates to the plates 2. Add 100 μL tracer 3. Incubate at room temperature for 2 hours (or overnight) 4. Wash 5 x with wash solution with a suitable plate washer ...

In Vitro Measurement of the Second Messenger cAMP: RIA vs. FlashPlate

...ate, into LP4 tubes. The remaining components (i.e., standard cAMP [ 125 I] tracer and cAMP antiserum complex) were also added manually. After overnight incub...standard curve was pipetted manually into the plates, but the cAMP [ 125 I] tracer was added by the robot to all wells. After overnight incubation, the FlashP...

Tracer in Biological Products

Mouse GM CSF ELISA construction Kit from Antigenix America Inc.

Description:... Mouse GM CSF Construction Kit provides antigen affinity purified polyclonal capture and tracer antibodies, and antigen standard for development of approximately ten microplate assays....
Company:Antigenix America Inc.

Human BMP 2 ELISA construction Kit from Antigenix America Inc.

Description:... Human BMP 2 Construction Kit provides antigen affinity purified polyclonal capture and tracer antibodies, and antigen standard for development of approximately ten microplate assays....
Company:Antigenix America Inc.

Tracer in Biological Dictionary

Technology transfer

...income to FAURC which is distributed ... Technology Transfer -Science tracer Bullet 93-5 : Science tracer Bullets - Research Finding Aids from the Library of Congress, Science Refer...