Toxic

Solution to Pollution: New Bacteria Eats Toxic Waste

Utah State University researchers recently discovered a new bacteria that is a natural cleanser for contaminated soil. The bacteria, now being used around the world, is an inexpensive and highly effective solution to pollution. “This project shows mother nature’s capability to be a master engineer,?said Ron Sims, biological and irrigation engineering department head. “Past disposal practi...

New comparative toxicogenomics database

Scientists at St. Jude Children's ResearchHospital have discovered that the shape of a protein on the surface ofpneumonia bacteria helps these germs invade the human bloodstream. Thisfinding, published Dec. 16 online by the EMBO Journal, could helpscientists develop a vaccine that is significantly more effective atprotecting children against the disease. The St. Jude researchersdetermined t...

New therapy for HIV/AIDS eliminates needles and excessive toxicity

A team led by Johns Hopkins scientists hasfound the first clear evidence that the process behind the human immunesystem's remarkable ability to recognize and respond to a milliondifferent proteins might have originated from a family of genes whoseonly apparent function is to jump around in genetic material. essentially cut...

Duke Chemists Isolating Individual Molecules Of Toxic Protein In Alzheimer's, Parkinson's Disease

To understand the formation of the brain-clogging deposits that cause such disorders as Alzheimer's and Parkinson's diseases, Duke University chemists have figured out how to capture and "micromanipulate" the single molecular building blocks of the deposits. Their aim is to understand the detailed assembly process for the toxic protein called amyloid plaque. Such basic understanding, they...

MetaChip provides quick, efficient toxicity screening of potential drugs

A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the U...

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Toxic at Biology Products

In Vitro Toxicity Testing Protocols, Vol 43 from Promega

Description:S. O'Hare & C.K. Atterwill • In vitro toxicity techniques for regular lab use. Ex vivo techniques are also covered with the aim of reducing and refining the use of animals in the future....
Company:Promega

Cytotoxicity Fluorometric (green / red) Assay Kit, LIVE/DEAD® from Molecular Probes (Invitrogen)

Description:LIVE/DEAD® Cell-Mediated Cytotoxicity Kit *for animal cells* *2000 assays*...
Company:Molecular Probes (Invitrogen)

Toxic at Biology Technology

Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice or Rats

Reliable Assessment of Micronuclei for Genotoxicity Testing in Mice orRats Precise and cost-effective micronucleus analysis made easy with theicroFlow Micronucleus Analysis Kit Litron Laboratories, Rochester, NY Mark J. Dycaico<br...

Versatile Transfection Reagent Offers Low Toxicity and Consistent Performance

Stratagene transfection reagent offersimproved, consistent transfections for both adherent cells and cells growing insuspension. In this article, we summarize the results of several experimentsthat characterize the eff...

Low-Toxicity, Lipid-Mediated Transfection of Mammalian Cells

Stratagene Cloning Systems Clonetics Corporation, Walkersville, Maryland LipoTAXI transfection reagent is a novel liposome reagent that offerslow cellular toxicity and high transfection efficiencies for adhe...

High-Efficiency Transfections Achieved with New Low-Toxicity Reagent

Nonliposomal formulation yields high efficiencies in a variety oftransfection conditions Stratagene Introducing foreign DNA into eukaryotic cells requires high-potencytransfections, which demand superior quality transfection reagents that areefficient, have low toxicity, and wor...

LIVE/DEAD Viability/Cytotoxicity Assay for Animal Cells Using the SpectraMax Gemini XS Fluorescence Microplate Reader (MaxLine Application Note #43)

Anne T. Ferguson, Ph.D. Molecular Devices Corporation This application note describes the use of the SPECTRAmax Viability/Cytoxicity Assay Kit for animal cells. This assay uses two fluorescent dyes, calcein AM (cal...

Toxic at Biology Definition

Cytotoxic T cell

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Toxic at Biology Dictionary

Cytotoxic T cell

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Toxic at Medicine News

B Vitamin protects and lowers toxicity of Arthritis Drug

Rheumatoid arthritis is an autoimmune disease that most often affects women in their 30s and 40s, especially women.The illness causes the immune system to attack the joints, which can cause pain, inflammation and joint destruction. Methotrexate is the standard drug used to treat the condition, but one third of the patients discontinue treatment early due to toxicity.//...

Toxic effects common with AIDS treatments

High levels of toxic effects associated with antiretroviral treatment for HIV have been recorded and quantified by a group of Swiss researchers in a study published this week in The Lancet. If efficacy levels of drug combinations are similar, treatment choice will depend on the toxic effects of the drugs. Therefore, the data may be useful as a reference for future analyses of adverse effects of d...

Healthy Medicine Or Harmful Intoxicant?

Is it a healthy, naturally occurring substance with many health benefits or a deadly intoxicant with no legitimate medical use? GHB -- gamma hydroxy butyric acid -- hailed as a wonder drug for the first 30 years// of its career, has been blamed as an illegal killer for the past 12 years. Many blame GHB for thousands of deaths and emergency room visits, while others claim its unrivaled uses as a p...

Doctors warned of fluoride toxicity

In the recent Journal of American Dental Association (JADA), doctors are warned against possibility of fluoride toxicity while prescribing fluoride dosage //to patients with oral problems. High concentrations of fluoride dosage are often prescribed to patients to check caries, especially those suffering from mouth cancer. In the recent issue of JADA, authors Frederick C. Eichmiller, N...

Toxic chemicals found in domestic products poisoning newborn babies

Recent research study has found that baby in the womb of pregnant women can be damaged by chemicals found in perfumes and household cleaning products. It was also found that these chemicals reach the baby from// the mother through the umbilical cord. The study was conducted in 27 newborn babies and 42 new mothers. The samples were tested for 8 groups of chemicals. All the tested samples were posi...

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Toxic at Medicine Products

Liquichek Qualitative Urine Toxicology Control

Description:Liquichek Qualitative Urine Toxicology Control is a liquid control designed for use with qualitative rapid urine drug screen panels, including Point of Care (POC) Drugs of Abuse (DOA) test kits like Bio-Rad TOX/See, Biosite Triage and other brands. The package insert includes qualitative results (+/) for popular kits and recovery values by gas chromatography (GC) and other quantitative methods....
Company:Bio-Rad Laboratories

Irinotecan Toxicity

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Toxic-Shock Syndrome Panel

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Toxic Shock Syndrome Antibody, MAID

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Toxic-Shock Syndrome Panel, MAID

Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...
Company:ARUP Laboratories

Toxic at Medicine Technology

Pixantrone Combination Therapy for First-line Treatment of Aggressive Non-Hodgkin's Lymphoma Results in Reduction in Severe Toxicities Including Heart Damage When Compared to Doxorubicin-based Therapy

Positive interim results prompt request for meeting with FDA SEATTLE, July 11, 2007 /PRNewswire-FirstCall/ -- CellTherapeutics, Inc. (CTI) announced today that interim results ofits phase II/III trial comparing CPOP-R, in which pixantrone issubstituted for doxorubicin in standard CHOP-R first-line treatmentof patients with aggressive non-Hodgkin's lymphoma (NHL), resultedin essentially al...

RTA 402 Shown to Protect Animals Against Toxicities of Standard Cancer Treatments

IRVING, Texas--(BUSINESS WIRE)--Jun 29, 2007 - ReataPharmaceuticals, Inc. today announced the presentation of newpreclinical data showing their lead anti-cancer agent, theSynthetic Triterpenoid RTA 402, is effective at protecting againstcommon toxicities caused by traditional cancer treatments. Thisdata was presented at the annual meeting of the MultinationalAssociation of Supportive Care i...

Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone

Interim results in a randomized phase II/III clinical trialanticipated later this year SEATTLE, June 26, 2007 /PRNewswire-FirstCall/ -- CellTherapeutics, Inc. (CTI) announced the publication of preclinicalstudies, which demonstrate that treatment with pixantrone (BBR2778) resulted in minimal or no significant cardiotoxicity, whiledoxorubicin and mitoxantrone induced significant cardiac da...

Toxic at Medicine Dictionary

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