Mouse with designer liver has enhanced glucose tolerance, insulin response
A collaborative effort led by The Burnham Institute's Gen-Sheng Feng has created a mouse with improved glucose tolerance and insulin activity in the liver, and generated new findings about insulin-signaling in the liver that could prove useful in understanding the pathogenesis of type 2 diabetes. These results, to be published by Nature Medicine in May, were made available to the scientific commu...Lactose intolerance linked to ancestral environment
Got milk? Many people couldn't care less because they can't digest it. A new Cornell University study finds that it is primarily people whose ancestors came from places where dairy herds could be raised safely and economically, such as in Europe, who have developed the ability to digest milk. On the other hand, most adults whose ancestors lived in very hot or very cold climates that couldn...Inhibition of morphine tolerance by spinal melanocortin receptor blockade
Recent research suggests that the melanocortin system is an important component influencing the changes in the spinal neuronal plasticity observed after chronic morphine administration//. The chronic use of morphine is accompanied by the development of morphine tolerance, which is one of the major problems associated with opiate treatment. Possible modulation of opioid effects by melanoc...Pain Tolerance Improved By Transcendental Meditation
Researchers have found that people who practice Transcendental Meditation have increased pain tolerance. In a research conducted among 12 healthy //long-term transcendental meditators and 12 healthy controls, researchers found that the people practicing meditation had 40-50% lower brain response to pain than the healthy controls not practicing meditation. They also found that when these...Gluten Intolerance Quadruples Susceptibility to Tuberculosis
People who are gluten intolerant run four times the risk of developing active tuberculosis (TB) infection, suggests research published ahead of print in Thorax. // Gluten intolerance, or coeliac disease, is a chronic inflammatory condition of the small bowel, caused by an exaggerated immune response to the gluten found in wheat, barley, and rye. It affects up to 1% of the...Brain development in teens curbed by alcohol tolerance
According to a study published on Tuesday, the younger brains of teens are capable of withstanding alcohol’s effects on social behavior.// However, the researchers found that this enhanced alcohol tolerance may make teens indulge in heavy drinking that could result in permanent damage to the under-developed regions of the brain. They used adolescent rats as substitutes for t...Exercise Intolerance In Heart Failure Patients Is Explored By Researchers
A new study conducted by researchers at Wake Forest University Baptist Medical Center have found out that blood flow to the legs is relatively // normal in people with diastolic heart failure, suggesting other potential causes of their inability to do everyday activities. 'Reduced tolerance for physical activity is the primary symptom of diastolic heart failure, and it greatly affects...Glucose Tolerance Test, Pregnancy
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