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Tigecycline in Medical News

FDA Approves New Indication for Wyeth's TYGACIL (tigecycline) for the Treatment of Adult Patients with Community-Acquired Bacterial Pneumonia

... TYGACIL is contraindicated in patients with known hypersensitivity to tigecycline TYGACIL should be administered with caution in patients with known ...ant medications. Patients who develop abnormal liver function tests during tigecycline therapy should be monitored for evidence of worsening hepatic function. Ad...

Broad Spectrum Antibiotic Available for Antibiotic Resistant Bacteria

...drugs to treat these diseases. The introduction of tigecycline in the UK comes at absolutely the right time and w...ld pose an even greater risk to public health.4, 5 tigecycline is one of a few new antibiotics with measured acti... 24th April 2006 and is available in the UK today. tigecycline is indicated for the treatment of complicated infe...

Tigecycline – New Generation Tetracycline With Broad Spectrum Antibacterial Activit

...es from United Kingdom have found a new antibiotic tigecycline which belongs to the family of new generation of T...rug efflux. But, the new generation tetracycline - tigecycline is not affected by either of these mechanisms. ... Two clinical studies proving the active effect of tigecycline as lead to FDA approval of...
Tigecycline in Medical Technology

Rib-X Pharmaceuticals Reports Positive Top-Line Results from Phase 2 Study of Delafloxacin

...) of delafloxacin were as efficacious as the FDA approved dosing regime for tigecycline in the treatment of complicated skin and skin structure infections (cSSSI)....h cSSSI for 5 to 14 days, as compared to the FDA approved dosing regime for tigecycline (TYGACIL, Wyeth Pharmaceuticals) for the same time period. Delafl...

Rib-X Pharmaceuticals Initiates Phase 2 Trial for RX-3341 In Complicated Skin and Skin Structure Infections

...hospitalized cSSSI patients every 12 hours for 5 to 14 days, as compared to tigecycline (Tygacil(TM)). The study's primary endpoint is the assessment of RX-3341 ef...for the study is the assessment of clinical efficacy of RX-3341 compared to tigecycline in patients with cSSSIs caused by methicillin- resistant Staphylococcus aur...

Wyeth Receives Approvable Letter from FDA for TYGACIL for the Treatment of Patients with Community-Acquired Pneumonia

...s in 28 countries across the globe and evaluated the efficacy and safety of tigecycline compared with levofloxacin in subjects hospitalized with CAP. Indications...- TYGACIL is contraindicated in patients with known hypersensitivity to tigecycline -- TYGACIL should be administered with caution in patients with known ...

More Clinical Data Required to Support European Approval of CAP Indication for TYGACIL

...acterial agents, including tigecycline, and may be life- threatening -- TYGACIL is contraindicated in patients with known hypersensitivity to tigecycline -- TYGACIL should be administered with caution in patients with known hypersensitivity to tetracycline class antibiotics -- Glycylcycline class ...
Tigecycline in Biological Technology

Rib-X Pharmaceuticals Announces Presentations at the 19th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)

...Comparing Two Clinical trials Doses of Delafloxacin to of antibiotics tigecycline in Adults Poster #1794 with Complicated Skin and Skin Structure Infectio...

Rib-X Pharmaceuticals Announces Positive Phase 2 Study Results for Delafloxacin and a $25 Million Financing

...ice daily (BID) and 450 mg BID; the comparator was tigecycline (TYGACIL(R), Wyeth Pharmaceuticals), the only broa...ble efficacy and improved tolerability relative to tigecycline at the FDA-approved dosing regimen for this indica...% and 92.5%, respectively, while the cure rate for tigecycline was 91.2%. Staphylococcus aureus was the m...
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(Date:4/17/2014)... An international team led by researchers at UC ... which plays a key role in cell division, also ... is the first time the complex has been shown ... cyclin B1/Cdk1 an excellent target to control cellular energy ... research was published online today in the journal ...
(Date:4/17/2014)... find a colored ribbon representing a disease. A pink ribbon ... ribbon does one think of with lung cancer?, Although white ... from the disease, black may be the only one they ... cancer patients, primarily smokers between the ages of 51 to ... often felt by these patients, the emotional toll it can ...
(Date:4/17/2014)... A new study has found that India,s shocking rates ... debt-ridden farmers who are clinging to tiny smallholdings ... ,cash crops, such as cotton and coffee, that are ... supports a range of previous case studies that point ... sector following the ,liberalisation, of the nation,s economy during ...
(Date:4/17/2014)... anti-malarial treatment that lost its status as the leading ... new lease of life, with new research indicating it ... could revive the use of the cheap anti-malarial drug ... claims the lives of more than half a million ... that causes malaria has developed resistance to chloroquine, but ...
(Date:4/16/2014)... HAMPTON, NJ (April 16, 2014): Celldex Therapeutics, Inc. ... Phase 1 study of CDX-1401 in solid tumors, including ... Translational Medicine (Vol 6 Issue 232). The data ... of clinical benefit in patients with very advanced cancers ...
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(Date:4/17/2014)... is available in German . ... the protection money demanded of him, he can expect his ... however, as fear of the consequences is enough to make ... parasitic birds, which lay their eggs in other birds, nests. ... brood parasites take their revenge by destroying the entire nest. ...
(Date:4/17/2014)... the Amazon help create tinderbox conditions for wildfires ... forest loss during drought years, according to a ... in the Amazon could reach a "tipping point" ... to large-scale loss of trees, making recovery more ... Penn State. , "We documented one of the ...
(Date:4/17/2014)... are implicated in many serious conditions such as heart ... target for drug therapies. Unfortunately, there is still much ... research provides fresh and unexpected insight into the structure ... - β-subunit molecules - which are responsible for ,fine-tuning, ... in the most recent edition of the Journal ...
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