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Thymine in Medical News

Gene Plays Role in Risk of Autism

...e chemical base adenine or thymine, children with autism tended to have the thymine variant. The researchers also found that children with autism were about 20 percent more likely to have inherited the thymine variant from their mothers than from their fathers. "This is a common va...

Genetic differences point to ethnic and racial disparities in colorectal cancer risk

...onsidered the wild type the version most common in the population as a whole and the CT or TT alleles carry a variant T, a point mutation in which a thymine nucleic acid is substituted for a cytosine in the genes DNA. Compared to CC, enzymatic activity of the CT mutation is reduced to 65 percent; TT has 30...

Study reveals how stem cells decide to become either skeletal or smooth muscle

...scribed one such regulatory sequence: the CArG box. The nucleotide building blocks of DNA chains may contain any one of four nucleobases: adenine (A), thymine (T), guanine (G) and cytosine (C). Any sequence of code starting with 2 Cs, followed by any combination of 6 As or Ts, and ending in 2 Gs is a CArG bo...

This is Why DNA Has Its Famous Helix Shape

...denine coil in a fairly regular fashion to form a helix of their own, while thymine chains take on a more random shape. The pure adenine strands exhibi...aking and unfolding of the helix. With no bonds between bases to break, the thymine chains' showed little resistance to extension and no plateau," Marszalek ex...

Gene Variant Responsible for Acquiring Intellect and Memory in Humans Identified

... it is expressed, resulting in proteins with new functions. Their study shows that the gene arose through a single mutation in the DNA, when a thymine nucleotide was exchanged for an adenine, causing 45 additional amino acids to be loaded into the protein that the gene expresses. Boffins say ...

Role of RNA in Checking the Development of Tumors

...n regulation of the dihydrofolate reductase gene (DHFR), determining whether the gene is "on" or "off". The DHFR gene produces an enzyme that controls thymine production, necessary in rapidly dividing cells. "Inhibiting the DHFR gene could help prevent the growth of neoplastic cancerous cells, ordinar...

Researchers from Emory University Undertake A New Genetic Mapping

...human genome is made from billions of chemical building blocks that appear in pairs. They explained that these blocks come in four types: adenine (A), thymine (T), cystosine (C), and guanine (G). The scientists have since then have been concentrating their attention for mapping the tiny variations in ...
Thymine in Biological News

Baylor researchers unravel mystery of DNA conformation

...ttitt. They found that when DNA is underwound in the same manner that you might underwind a spring, the forces induce one of two bases adenine or thymine to "flip out" of the sequence, thus relieving the stress that the molecule experiences. "It always happens in the underwound state," said Zechied...

Covering the bases: Quantum effect may hold promise for low-cost DNA sequencing, sensor applications

...d between them. Base pairing rules for DNA dictate that the hydrogen bonds work to join up appropriate nucleotide pairs like jigsaw piecesadenine with thymine and cytosine with guanine. The scanning tunneling microscope used in the present study features a delicate electrode tip held very close to the DN...

A new way to assemble cells into 3-D microtissues

...xample, from a simple repeat of two bases such as cytosine and adenine (CACACA...) on one strand, which binds to a complementary repeating sequence of thymine and guanine (TGTGTG...) on the other, up to sequences whose base order varies over the full length of the 20-base strand of synthetic DNA. The more co...

New computational technique allows comparison of whole genomes as easily as whole books

...e genome sequences using a reduced, two-letter alphabet - R for the purine nucleic acids, adenine and guanine, and Y for the pyrimidine nucleic acids, thymine and cytosine - to reduce the complexity of calculation. Using an optimal feature length of 18 base pairs, this test created a family tree identical to...

Finding that 1-in-a-billion that could lead to disease

...t. After studying DNA breathing by itself, the researchers then added UDG into the mix. They saw that UDG holds onto the normal DNA building block thymine (T) after it pops out of the DNA on its own. However, because T is not identical to U, UDG then lets it fall back into DNA helix. When the DNA con...

Scientists see DNA get 'sunburned' for the first time

...onds that form where they shouldn't -- between two thymine bases stacked together among the billions of bases...lly designed strands of DNA -- ones made solely of thymine bases, in order to boost the chance of observing a... Then they timed the reactions that caused the new thymine bonds to form. Kohler stressed that he and hi...

New study sheds light on 'dark states' in DNA

...experiments hinted at its existence, but this is the first time it has been shown to exist in three of the five bases of the genetic code -- cytosine, thymine and uracil. The detection of this dark state in single bases in solution increases the chances that it may be found in the DNA double helix, said ...

Uncovering DNA's 'sweet' secret

... the ladder) bind. The bases in normal DNA adhere to a somewhat strict binding scheme - guanine (G) binds with cytosine (C) and adenine (A) binds with thymine (T). In this "Watson-Crick" basepairing, the G:C bonds are much stronger than A:T or any other bonds. "In homo-DNA, the Watson-Crick base pairing ...

'Pinball protons' created by ultraviolet rays and other causes can lead to DNA damage

...cell replication and growth. DNA is made of four "bases," Adenine, Guanine, thymine and Cytosine, and each one pairs with its opposite to form bonds where the "information" of life is stored. Thus, Guanine pairs with Cytosine, and thymine with Adenine. The team at the University of Georgia studied how the rem...

Study finds 60 new genes controlled by DNA snippet

...latory sequence under examination was the CArG box. The nucleotide building blocks of DNA chains may contain any one of four nucleobases: adenine (A), thymine (T), guanine (G) and cytosine (C). Any sequence of code starting with 2 Cs, followed by any combination of 6 As or Ts, and ending in 2 Gs is a CArG bo...
Thymine in Biological Technology

J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology

... the laboratory the 582,970 base pair M. genitalium genome using the chemical building blocks of DNA -- adenine (A), guanine (G), cytosine (C) and thymine (T). While this was a big advance, it took several years to come to fruition and in the end was a tedious, multi-stage process in which the ...

Glossary for The BioPharm Guide to Fermentation and Cell Culture

...airs with guanine (G) and adenine (A) always links to thymine (T). In RNA molecules, adenine joins to uracil (U). . bat...sed on ribose, and with the base uracil (U) in place of thymine (T). Various forms of RNA are found: mRNA (messenger RN...

Inactivation of Contaminating Templates in PCR Using High Intensity Ultraviolet Light

...light is also an effective means of preventing carry-over contamination. 2,3,4 High intensity UV light induces the formation of thymine dimers which block the progress of the Taq polymerase, and thus contaminating carry-over products are not amplified. In this bul...
Thymine in Biological Definition

Genetic code

...ngs . The pyrimidine bases cytosine ( C ) and thymine ( T ) are smaller and only consist of one aromatic ring. In RNA however, thymine ( T ) is substituted by uracil ( U ) and the deo...is also a sequence of nucleotide bases, but there thymine takes the place of uracil.) The standard geneti...

DNA sequence

...and, The possible letters are A , C , G , and T , representing the four nucleotide subunits of a DNA strand ( adenine , cytosine , guanine , thymine ), and typically these are printed abutting one another without gaps, as in the sequence AAAGTCTGAC. This coded sequence is sometimes referred to as...

DNA

... of the bases means that there are four kinds of nucleotides, which are commonly referred to by the identity of their bases. These are adenine (A), thymine (T), cytosine (C), and guanine (G). In a DNA double helix, two polynucleotide strands can associate through the hydrophobic effect . Specifi...

Double helix

...s Watson and Francis Crick in 1953. They showed that DNA is made up of two complementary, antiparallel strands of the bases Guanine , Adenine , thymine , and Cytosine , covalently linked through phosphodiester bonds . Each strand forms a helix, and the two helices are held together through hydrog...

Genetic code

...ngs . The pyrimidine bases cytosine ( C ) and thymine ( T ) are smaller and only consist of one aromatic ring. In RNA however, thymine ( T ) is substituted by uracil ( U ) and the deo...is also a sequence of nucleotide bases, but there thymine takes the place of uracil.) The standard geneti...

Nucleoside

... Deoxynucleoside Adenine Adenosine A Deoxyadenosine dA Guanine Guanosine G Deoxyguanosine dG thymine Thymidine T Deoxythymidine dT Uracil Uridine U Deoxyuridine dU Cytosine Cytidine C Deoxycyti...

Nucleotide

...d letter indicates the nucleobase: G: Guanine A: Adenine T: thymine C: Cytosine U: Uracil not present in DNA, but takes the place of thymine in RNA The third and fourth letters indicate the length of the attache...

Polymerase chain reaction

...ino acid isoleucine might be "ATH", where A stands for adenine , T for thymine , and H for adenine , thymine , or cytosine . (See genetic code for further details about codons ) Us...

Primer

...ino acid isoleucine might be "ATH", where A stands for adenine , T for thymine , and H for adenine , thymine , or cytosine . (See genetic code for further details about codons ) Us...

Purine

...bases in nucleic acids , adenine and guanine , are purines. In DNA , these bases form hydrogen bonds with their complementary pyrimidines thymine and cytosine . purine pyrimidine A T G C In RNA , the complement of A is uracil instead of thymine: purine pyrimid...
Thymine in Biological Dictionary

Thymine

Thymine is one of the four bases in the nucleic acid of DNA that are represented by the letters G–C–A–T. The others are adenine, guanine, and cytosine. Thymine (T) always pairs with adenine. Thymine is also known as 5-methyluracil, a pyrimidine nucleobase. As the name suggests, thymine...

Uracil

.... Uracil is therefore structurally analogous to thymine in molecules of DNA. ... Uracil is one of th...he nucleic acids DNA and RNA. ... Uracil (U), thymine (T), and cytosine (C) are pyrimidine derivati.... Uracil is therefore structurally analogous to thymine in molecules of DNA. ... Definition of uracil...

Ribonucleotides

...ne or pyrimidine base is linked to a ribose molecule. The base may be adenine (A), guanine (G), cytosine (C), or uracil (U). Note that thymine (T), which is found in deoxyribonucleotides, is not found as a ribonucleotide in living beings. Ribonucleotides have one, two, or three phosphate g...

Pyrimidine

...re either degraded or salvaged for ... Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and ... Nucleobases: Adenine - thymine - Uracil - Guanine - Cytosine - Purine - Pyrimidine ... pyrimidines , purine pyrimidine ... pyrimidine ... The simplest member, pyrimidin...

Purine

...lic, aromatic, organic compound, consisting of a ... Nucleobases: Adenine - thymine - Uracil - Guanine - Cytosine - Purine - Pyrimidine ... Online Medical...enine, A - (biochemistry) purine base found in DNA and RNA; pairs with thymine ... The Purine Research Society was formed in 1986 by parents of ... ...

Guanine

...large) DNA double-helix DNA model A. adenine T. thymine C. cytosine G. guanine D. deoxyribose P ... adenine, cytosine, guanine , and thymine (A, ... Guanine , a two-ring molecular struct...se pairing forms three ... Nucleobases: Adenine - thymine - Uracil - Guanine - Cytosine - Purine - Pyrimid...

Double stranded

...ruses. ... Double - stranded (ds) RNA viruses are a diverse group of viruses ... (Click to enlarge) DNA double -helix DNA model A. adenine T. thymine C. ... The stabilization of duplex ( double - stranded ) DNA is also dependent on base stacking. ... A. Large scale double - stranded DNA is...

Double helix

...which strands linked by hydrogen bonds form a spiral configuration, with the two (Click to enlarge) DNA double - helix DNA model A. adenine T. thymine C. cytosine G. guanine D. deoxyribose P ... form a double -stranded helix , with the bases ... Download Double Helix Drum & Bass...

Deoxyribonucleotide

...ivo bacteriophage T4 DNA replication. Intrinsic control of synthesis of thymine and 5-hydroxymethylcytosine ... GO:0009265 : 2'- deoxyribonucleotide b... deoxyribonucleotide units with a nitrogenous base of adenine, guanine, thymine or cytosine. Under certain conditions, uracil can ... Processes and r...

Cytosine

...large) DNA double-helix DNA model A. adenine T. thymine C. cytosine G. guanine D. deoxyribose P ... bases—adenine, cytosine , guanine, and thymine ... Prebiotic cytosine synthesis: A critical...nd implications for the ... Nucleobases: Adenine - thymine - Uracil - Guanine - Cytosine - Purine - Pyrimid...
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