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Thrombocytopenic in Medical News

Eltrombopag studied in Idiopathic Thrombocytopenic Purpura

NEW YORK (Nov. 29, 2007) -- There are estimated to be between 50,000 -- 100,000 individuals in the U.S. diagnosed with chronic Immune Thrombocytopenic Purpura (ITP), an autoimmune disease that dramatically reduces the number of platelets in their blood -- causing bruises, nosebleeds and, sometim...

Rigel R788 Raises Platelet Counts in Immune Thrombocytopenic Purpura (ITP) Patients in Phase 2 Study

SOUTH SAN FRANCISCO, Calif., Nov. 9 /PRNewswire-FirstCall/ -- Rigel Pharmaceuticals, Inc. (Nasdaq: RIGL ) today announced results of its Phase 2 clinical study of R788, a novel, oral Syk kinase inhibitor, in patients with Immune Thrombocytopenic Purpura (ITP). The single-center, open-label, d...

Drug Boosts Platelet Production, Reversing Immune Thrombocytopenic Purpura

Attacking a platelet-depleting autoimmune disease in a whole new way, an experimental drug is helping patients with immune thrombocytopenic purpura (ITP) once again// produce healthy amounts of platelets -- with no major side effects. That's the conclusion of a new, multicenter study led by D...

New Data Demonstrate RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment May Improve Health Outcomes and Reduce Hospitalizations in Patients with Schizophrenia

...y in patients at risk for aspiration pneumonia. Priapism has been reported. Severe priapism may require surgical intervention. Thrombotic thrombocytopenic Purpura (TTP) has been reported. Administration: Care should be taken to avoid inadvertent injection into a blood vessel. Suicide: The ...

FDA Grants Approval for Use of RISPERDAL(R) CONSTA(R) as Both a Monotherapy and Adjunctive Therapy in the Maintenance Treatment of Bipolar I Disorder

...y in patients at risk for aspiration pneumonia. Priapism has been reported. Severe priapism may require surgical intervention. Thrombotic thrombocytopenic Purpura (TTP) has been reported. Administration: Care should be taken to avoid inadvertent injection into a blood vessel. Suicide: The ...

New Bill Offers Medicare Reimbursement Fix for Intravenous Immune Globulin

...lammatory demyelinating polyneuropathy, Guillain-Barre syndrome, idiopathic thrombocytopenic purpura, myasthenia gravis, myositis, multiple sclerosis, just to name a fe...polyneuropathy; and Craig Orfield, staff of Senator Enzi who has idiopathic thrombocytopenic purpura. "Since 2005, patient access to IVIG has diminished, and Medic...

European Commission and United States Food and Drug Administration (FDA) Both Approve New Options for Patients With Certain Primary Brain Tumors

...n laboratory abnormalities and adverse events were combined, Grade 3 or 4 neutropenia occurred in 8% and Grade 3 or 4 platelet abnormalities including thrombocytopenic events occurred in 14% of patients treated with temozolomide. Most common adverse reactions in the trial in AA patients overall and Grade 3/4, re...

3SBio Inc. Files for SFDA Approval for TPIAO Label Extension for the Treatment of ITP

...n December 30, 2008 with the Chinese State Food and Drug Administration (SFDA) for approval of a TPIAO label extension for the treatment of idiopathic thrombocytopenic purpura (ITP) in China. If the extension is approved, 3SBio expects that TPIAO for ITP will be the only treatment of this kind available in China. ...

PEGASYS(R) Proven Effective as Hepatitis C Treatment for Latino Patients, According to Article in The New England Journal of Medicine

...isorders and diabetes mellitus), autoimmune disorders (including idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, psoriasis, lupus, rheumatoid arthritis and interstitial nephritis)...

Novel therapeutic approaches may improve patient outcomes in several platelet disorders

...nation therapy for previously untreated idiopathic thrombocytopenic purpura (ITP), an investigational oral treatment f...dult patients with previously untreated idiopathic thrombocytopenic purpura (ITP). The results of this study indicate ...Term Treatment of Patients With Chronic Idiopathic thrombocytopenic Purpura (ITP): Results of a Phase III, Double-Blin...
Thrombocytopenic in Medical Technology

Nplate(R) Approved in the European Union for the Treatment of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)

First and Only Approved Platelet Producer in Europe Represents New Treatment Approach for Serious Chronic Autoimmune Disorder ZUG, Switzerland, Feb. 6 /PRNewswire-FirstCall/ -- Amgen (Nasdaq: AMGN ) today announced that the European Commission (EC) has granted marketing authorisation for Np...

RISPERDAL(R) CONSTA(R) (Risperidone) Long-Acting Treatment Delayed the Time to Relapse in Patients with Bipolar I Disorder

...y in patients at risk for aspiration pneumonia. Priapism has been reported. Severe priapism may require surgical intervention. Thrombotic thrombocytopenic Purpura (TTP) has been reported. Administration: Care should be taken to avoid inadvertent injection into a blood vessel. Suicide: The ...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

...isorders and diabetes mellitus), autoimmune disorders (including idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, psoriasis, lupus, rheumatoid arthritis and interstitial nephritis)...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...isorders and diabetes mellitus), autoimmune disorders (including idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, psoriasis, lupus, rheumatoid arthritis and interstitial nephritis)...

Long-term Follow Up Interim Data Show Nplate(TM) Increased and Sustained Platelet Counts in Adult Chronic ITP Patients

...romiplostim) in adult patients with chronic immune thrombocytopenic purpura (ITP). Chronic ITP is a chronic and seriou...dence of clinically significant, treatment-related thrombocytopenic events and platelet transfusions. Nplate also impr...penia in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) who have had an insufficient respons...

CHMP Recommends Approval in the European Union (EU) for New Options for Patients With Certain Primary Brain Tumors

...n laboratory abnormalities and adverse events were combined, Grade 3 or 4 neutropenia occurred in 8% and Grade 3 or 4 platelet abnormalities including thrombocytopenic events occurred in 14% of patients treated with temozolomide. Most common adverse reactions in the trial in AA patients Grade 3/4 and overa...

Novel Therapeutic Approaches May Transform Treatment and Improve Patient Outcomes in Several Platelet Disorders

...nation therapy for previously untreated idiopathic thrombocytopenic purpura (ITP), an investigational oral treatment f...dult patients with previously untreated idiopathic thrombocytopenic purpura (ITP). The results of this study indicate ...Term Treatment of Patients With Chronic Idiopathic thrombocytopenic Purpura (ITP): Results of a Phase III, Double-Blin...

GSK Reports PROMACTA(R) (eltrombopag) Significantly Increased Platelet Counts and Reduced Bleeding in Long-Term Study of Patients With Chronic ITP

...ents requiring the use of supportive ITP medications occurred in 3 severely thrombocytopenic patients within one month following the discontinuation of PROMACTA; none w... M, Robinson N, Bennett D. Prevalence estimates of adult chronic idiopathic thrombocytopenic purpura (ITP). J Thromb Haemost. 2008; 6(4): 711 - 712. ...

FDA Approves Promacta(R) (Eltrombopag), the First Oral Medication to Increase Platelet Production for People With Serious Blood Disorder

...penia in patients with chronic immune (idiopathic) thrombocytopenic purpura (ITP) who have had an insufficient respons... supportive ITP medications occurred in 3 severely thrombocytopenic patients within one month following the discontinu... JN. Management of patients with refractory immune thrombocytopenic purpura. J Thromb. Haemost. 2006;4(8):1664-72. ...

New Study Shows that PEGASYS(R) Regimen Provides Higher Sustained Virological Response Rates for Hepatitis C Patients

...docrine disorders (including thyroid disorders and diabetes mellitus), autoimmune disorders (including idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, psoriasis, lupus, rheumatoid arthritis and interstitial nephritis), pulmonary disorders (dyspnea, pneumonia, bronchiolitis obliterans, inters...
Thrombocytopenic in Medical Dictionary

Thrombocytopenia

...latelets in the blood. ... thrombocytopenia . thrombocytopenic purpura. thrombotic thrombocytopenic purpura ... diseases can cause thrombocytopenia...circulating platelets. ... INTRODUCTION Immune thrombocytopenic purpura (idiopathic...

Purpura

... calves. Meningococcemia on the leg ... Idiopathic thrombocytopenic purpura (ITP) ... Petechiae, purpura , and ... calves. Meningococcemia on the leg ... Idiopathic thrombocytopenic purpura (ITP) ... Purpura . Authoritative f... PURPURA AND ABNORMAL BLEEDING ... Idiopathic thrombocytopenic purpura (ITP) is a bleeding condition in which...

Itp

... Idiopathic thrombocytopenic purpura ( ITP ) is the condition of having a low...against platelets, ITP is also known as immune thrombocytopenic purpura or immune-mediated... Providing news...Reviews,Comms,Events,Hardware , ... Idiopathic thrombocytopenic purpura ( ITP ) is a bleeding condition in whi...

Idiopathic

... disease of its own kind." Idiopathic thrombocytopenic purpura (ITP) is the condition of having a low ...s against platelets, ITP is also known as immune thrombocytopenic purpura or immune-mediated... " Idiopathic ... My father has been diagnosed with idiopathic thrombocytopenic purpura. ... divided into two types — idiopathic ...

Hus

...ember: ... In TTP- HUS , thrombi caused by clumps of platelets block small blood vessels. ... Hemolytic-uremic syndrome ( HUS ) and thrombotic thrombocytopenic purpura (TTP) ... Home " HUS /TTP " Overview, Causes and Risk Factors, Symptoms, Diagnosis, Treatment ... HUS symptoms, causes, diagnosis, an...

Hemolytic anemia

...ood cells have a Hemolytic disease of the newborn Also known as erythroblastosis neonatorum, ... Autoimmune hemolytic anemia · Idiopathic thrombocytopenic purpura · Bullous ... Hemolytic anemia is a disorder in which the red blood cells are destroyed faster than the bone marrow can produce ...

Ecchymosis

...essure. ... Aging skin ( ecchymosis ) Idiopathic thrombocytopenic purpura (petechiae and purpura) ... Bleeding...mosis . ... Aging skin ( ecchymosis ) Idiopathic thrombocytopenic purpura (petechiae ... Eye injuries can be...essure. ... Aging skin ( ecchymosis ) Idiopathic thrombocytopenic purpura (petechiae and purpura) ... List of ...
Thrombocytopenic in Biological News

Lancet study supports new, highly effective treatment for blood disorder

...ividuals in the U.S. diagnosed with chronic immune thrombocytopenic purpura (ITP), an autoimmune disease that dramatic...penia in patients with chronic immune (idiopathic) thrombocytopenic purpura who have had an insufficient response to c...rts equity ownership in GlaxoSmithKline. Immune thrombocytopenic purpura (ITP) is an autoimmune disease in which an...

Eltrombopag effective for hepatitis C patients with low blood-platelet counts

... England Journal of Medicine, finding the platelet growth factor successfully increased platelet counts and decreased bleeding in patients with Immune thrombocytopenic Purpura (ITP), an autoimmune disease that dramatically reduces the number of platelets in their blood. (Dr. Bussel is an Advisory Board Member for Gla...
Thrombocytopenic in Biological Technology

3SBio Inc. Announces Unaudited Fourth Quarter and Fiscal Year 2008 Results

...urally occurring IL-2. -- In December 2008, the Company filed for approval of a TPIAO label extension for the treatment of idiopathic thrombocytopenic purpura (ITP) in China, representing the first of a series of indications that the Company plans to pursue to build and grow TPIAO...

Amgen's Third Quarter 2008 Adjusted Earnings Per Share Increased 14 Percent to $1.23

...ncrease platelet production for the treatment of thrombocytopenia in splenectomized (spleen removed) and non-splenectomized adults with chronic immune thrombocytopenic purpura (ITP). Nplate, the first FDA-approved peptibody protein, works by raising and sustaining platelet counts, representing a novel approach for th...

3SBio Inc. Announces Second Quarter 2008 Results

...sted other treatment options. TPIAO for ITP We have achieved our enrollment goal for the Phase III trial for TPIAO for the treatment of idiopathic thrombocytopenic purpura (ITP). We remain on track to file the application for approval with the SFDA in the fourth quarter of 2008. TPIAO Phase IV Studies To maxi...

ProMetic announces Octapharma publication of PRDT'S prion removal resin in Octaplas(R) manufacturing process at 30th International Congress of the International Society for Blood Transfusion meeting in Macao SAR, China

...plex and isolated coagulation disorders - both congenital and acquired - where no specific coagulation factor concentrate is available, and thrombotic thrombocytopenic purpura ("TTP") - usually in conjunction with plasma exchange. Octaplas(R) is fully licensed in 29 countries worldwide, and roughly 6 million bags hav...

Vermillion Announces First Quarter 2008 Financial Results and Business Progress

... until its diagnostic tests are commercialized. During the first quarter of 2008, products revenue of $5,000 was generated from the sale of thrombotic thrombocytopenic purpura ("TTP") test component materials to The Ohio State University Research Foundation ("OSU"). Total operating expenses decreased in the first q...

3SBio Inc. Announces First Quarter 2008 Results

...quarter of 2008. TPIAO for ITP As we announced in the last quarter earnings release, the Phase III trial for TPIAO for the treatment of idiopathic thrombocytopenic purpura (ITP) was delayed due to a higher than expected patient drop-off rate (patients left the hospital before the required observation time) as a r...

CSL Behring Signs Agreements With Canadian Blood Services and Hema-Quebec to Supply Life-Saving Therapies

...perature (25 C) for a period of 24 months. Privigen(R) is indicated for the treatment of primary and secondary immune deficiencies as well as immune thrombocytopenic purpura (ITP), a disorder characterized by low platelet counts due to the presence of auto-antibodies directed against the patient's own platelets. ...

Vermillion Summarizes Recent Accomplishments and 2007 Financial Results; Outlines 2008 Business Milestones

...on made significant clinical and commercial advancements in our diagnostic programs for peripheral artery disease (PAD), ovarian cancer and thrombotic thrombocytopenic purpura (TTP)," said Gail Page, President and CEO of Vermillion. "Our vision is to provide novel diagnostic tools to physicians in an effort to improv...

3SBio Inc. Announces Unaudited Fourth Quarter and Fiscal Year 2007 Results

...icacy of the product and expect filing with SFDA in Q3 of 2008. The initial results of the Phase III trial for TPIAO for the treatment of idiopathic thrombocytopenic purpura (ITP) demonstrated excellent efficacy and a high safety profile based on our data to date. Enrollment has been completed, but we experienced a...

FDA Approves New 300mg Loading Dose Tablet for PLAVIX(R) (clopidogrel bisulfate)

...rials. (See ADVERSE REACTIONS.*) -- As part of the worldwide post marketing experience with PLAVIX, there have been cases of reported thrombotic thrombocytopenic purpura (TTP), some with fatal outcome. TTP has been reported rarely following use of PLAVIX, sometimes after a short exposure ( conditio...
Thrombocytopenic in Biological Dictionary

Thrombocytes

...h an introduction, the fluid systems, innate immunity ... leukocytes (white blood cells or WBCs), and thrombocytes (platelets) ... Idiopathic thrombocytopenic purpura (ITP) is a bleeding condition in which the ... Platelets also are called thrombocytes (THROM-bo-sites) ... What does it mean when a veter...
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