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Thrombocytopenia in Medical News

ThromboGenics Begins Preclinical Development of Anti-VPAC Antibody for Thrombocytopenia

LEUVEN, Belgium, November 14 /PRNewswire/ -- - Key Research Findings Published in the Leading Medical Journal `Blood' Validate Drug Target ThromboGenics NV (Euronext Brussels: THR), a biotechnology company focused on vascular disease, announces today that it will progress with the developmen...

Rigel Announces Second Quarter 2009 Financial Results

... to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis thrombocytopenia and asthma, as well as in cancer. This press release contains "forward-looking" statements, including statements related to the sufficiency of...

Rigel to Host Conference Call to Discuss Results of Its Phase 2b TASKi3 Clinical Trial of R788 in Rheumatoid Arthritis

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. Contact: Raul Rodriguez Phone: 650.624.1302 Email: invrel@rigel.com Media Contact: Susa...

Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer

...vs VELCADE, respectively) included: neutropenia (36 percent vs 22 percent), thrombocytopenia (33 percent vs 28 percent), anemia (25 percent vs 21 percent), fatigue (36 ... anemia (Hb less than 10 g/dL, 58 percent; less than 8 g/dL, 16 percent), thrombocytopenia (less than 150,000 platelets/mm3, 61 percent), nausea (18 percent), astheni...

New PICC Mimics Nature

... thrombus occlusion by instilling heparin into catheters between uses. However, many patients are allergic to heparin, which can cause heparin-induced thrombocytopenia (HIT). Some PICC manufacturers have addressed the thrombus problem by affixing valves to their catheters, which can limit placement methods and reliab...

Miami Physician Sentenced to 97 Months in Prison for Role in $10 Million Medicare Fraud Scheme

...blood was sent to a laboratory for analysis. In his plea, Rodriguez admitted to ordering that patients at Midway receive medications designed to treat thrombocytopenia despite knowing that the laboratory results had been falsified and that the patients did not actually have that condition. Midway was not the on...

Rigel to Present at Jefferies Healthcare Conference

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. Contact: Ryan Maynard Phone: 650.624.1284 Email: invrel@rigel.com ...

Rigel's R788 Evaluated in Phase 2 Trial in Multiple Cancers

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. This press release contains forwar d -looking statements, including, but not...

Poniard Pharmaceuticals Announces Positive Efficacy and Safety Data From Phase 2 Clinical Trial of Picoplatin in Men With Metastatic Prostate Cancer

...in almost 2 percent of patients.i Neutropenia was the main hematologic toxicity. In contrast with picoplatin monotherapy in previous studies, thrombocytopenia was less severe and less frequent with picoplatin administered in combination with docetaxel. "We continue to be encouraged by t...

Rigel to Present at JMP Securities Research Conference

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. Contact: Ryan Maynard Phone: 650.624.1284 Email: invrel@rigel.com ...
Thrombocytopenia in Medical Technology

R788 in TASKi3 Clinical Trial Does Not Meet Efficacy Endpoints in RA Patients Who Had Previously Failed Biologic Therapies - Results Incongruent

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. This press release contains "forward-looking" statements, including statements related to the potential ef...

Rigel's R788 Significantly Improves Rheumatoid Arthritis in Phase 2b Clinical Trial

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. This press release contains "forward-looking" statements, including statements related to the potential effica...

Rigel to Host Conference Call to Discuss Results of Its Phase 2b TASKi2 Clinical Trial of R788 in Rheumatoid Arthritis

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. Contact: Raul Rodriguez Phone: 650.624.1302 Email: invrel@rigel.com Media Contact: Susan C....

FDA Accepts sNDA for Alternative Dosing Regimen for Dacogen(R) (decitabine for injection) to Treat Patients with Myelodysplastic Syndromes (MDS)

...ng treatment with Dacogen and for two months afterwards. The most commonly occurring adverse reactions with Dacogen include neutropenia (90 percent), thrombocytopenia (89 percent), anemia (82 percent), pyrexia (53 percent), fatigue (48 percent), nausea (42 percent), cough (40 percent), petechiae (39 percent), consti...

SIMPONI(TM) (golimumab) Receives Positive Opinion From CHMP for Once-Monthly Subcutaneous Treatment of Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

... the development of a lupus-like syndrome. There have been postmarketing reports of pancytopenia, leukopenia, neutropenia, aplastic anemia, and thrombocytopenia in patients receiving TNF blockers. Cytopenias including pancytopenia, have been infrequently reported with SIMPONI in clinical trials. Discontinuat...

Investigational Cancer Drug BSI-201 Showed Clinical Benefit in 62% of Patients with Triple-Negative Metastatic Breast Cancer and Significantly Prolonged Survival

...ommon severe (grades 3 and 4) side effects included neutropenia [25/57 in patients treated with GC and BSI-201; 31/59 patients treated with GC alone], thrombocytopenia and anemia. No febrile neutropenia was observed in patients receiving BSI-201 combined with chemotherapy. BSI-201 did not add to the frequency or seve...

Study Showed Lilly's GEMZAR(R) (gemcitabine HCl for injection) Improved Progression-Free Survival in Cervical Cancer Patients

...ent-related toxicities. Most side effects were hematologic, including anemia (low red blood cell count), neutropenia (low white blood cell count) and thrombocytopenia (low blood platelet count). "While there have been tremendous advances in cervical cancer prevention in the form of early screening and vaccina...

Poniard Pharmaceuticals Announces Progression-Free Survival Data From Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer

...tistically significant for FOLPI as a potential neuropathy-sparing alternative to FOLFOX (p<0.0019). With regard to hematologic toxicities, thrombocytopenia and neutropenia were more frequent and severe with the FOLPI regimen compared with FOLFOX. However, only one episode of febrile neutropenia and no ble...

Video: Data on More Than 15 Novartis Oncology Compounds at ASCO Highlight Progress Toward Targeted Therapies for Diverse Tumor Types

...including neutropenia (3.6%-48%), anemia (1%-42%), thrombocytopenia (<1%-33%), and hepatotoxicity (approx 5%)--and ...ades 3/4) lab abnormalities included anemia (17%), thrombocytopenia (17%), neutropenia (8%), and increased creatinine ...including neutropenia (10%; 11%), anemia (3%; 9%), thrombocytopenia (0%; 1%), and hepatotoxicity (6%; 8%)--and severe ...

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

...hysema, bronchiolitis obliterans, pleural effusion, gastroenteritis, pancreatitis, gout, hyperglycemia, hyperthyroidism and hypothyroidism, autoimmune thrombocytopenia with or without purpura, rheumatoid arthritis, interstitial nephritis, lupus-like syndrome, sarcoidosis, aggravated psoriasis, urticaria, injection si...
Thrombocytopenia in Medical Products

PAP-4

Description:...istocetin cofactor), platelet aggregation and leukocyte aggregation. The PAP-4 may also be used for the evaluation and confirmation of Heparin Induced thrombocytopenia (HIT). Four channels allow four tests to be run simultaneously and independently. Select standard volumes or microvolume quantities to reduce sample a...
Company:Bio/Data Corporation

PAP-4CD

Description:...tocetin cofactor), platelet aggregation and leukocyte aggregation. The PAP-4CD may also be used for the evaluation and confirmation of Heparin Induced thrombocytopenia (HIT). Four channels allow four tests to be run simultaneously and independently. Select standard volumes or microvolume quantities to reduce sample a...
Company:Bio/Data Corporation

PAP-4D

Description:...stocetin cofactor), platelet aggregation and leukocyte aggregation. The PAP-4D may also be used for the evaluation and confirmation of Heparin Induced thrombocytopenia (HIT). Four channels allow four tests to be run simultaneously and independently. Select standard volumes or microvolume quantities to reduce sample a...
Company:Bio/Data Corporation

PAP-4C

Description:...stocetin cofactor), platelet aggregation and leukocyte aggregation. The PAP-4C may also be used for the evaluation and confirmation of heparin induced thrombocytopenia (HIT). Four channels allow four tests to be run simultaneously and independently. Select standard volumes or microvolume quantities to reduce sample a...
Company:Bio/Data Corporation
Thrombocytopenia in Medical Dictionary

Thrombocytopenia

... fever can cause thrombocytopenia by direct infection of ... thrombocytopenia (NAITP) ... Thrombocytopenia caused by Feline Leukemia Virus and Feline ... Features information on this disorder and its causes, incidence and risk factors. ... Thrombocytopenia is any disorde...

Thrombocyte

... on inside of the elbow or the ... Blood test to evaluate, bleeding disorders, purpura/petechiae, drug induced thrombocytopenia, idiopathic thrombocytopenia purpura, disseminated intravascular ... ...

Platelet

... information and support for those concerned about ITP, Immune (Idiopathic) thrombocytopenia Purpura. ... of The Platelet News, PDSA's quarterly ... Comprehensive... information and support for those concerned about ITP, Immune (Idiopathic) thrombocytopenia Purpura. ... appeared in The Platelet News, vol.4, no ... Abnormaliti...

Platelet count

...count are to assist in the diagnosis of ... thrombocytopenia — Comprehensive overview covers symptoms, causes, ... thrombocytopenia. 50 ... ... for people with thrombocytopenia to try to increase their platelet count ... di...low platelet count , including heparin. ... thrombocytopenia — Comprehensive overview covers symptoms, causes, ...

Lymphadenitis

... lymph nodes (also called lymph glands) ... Lymphadenitis may occur after skin infections or other bacterial infections, ... Idiopathic thrombocytopenia Purpura, Ileus, Immobilization, Immune System Development, Immunodeficiency, Immunoglobulin Deficiency Syndromes, Impetigo, Impulse ... More about...

Lice Infestation

... of the most common contagious childhood ... Contrary to popular belief, head lice infestation has little to do with personal ... Idiopathic thrombocytopenia Purpura, Ileus, Immobilization, Immune System Development, Immunodeficiency, ... A lice infestation , or pediculosis, is ... What are the signs...

Itp

...ave ITP often have purple bruises that appear on the skin or on the ... ... and support for those concerned about ITP , Immune (Idiopathic) thrombocytopenia Purpura. ... features 5 video stories from patients about their ITP experience. ... ITP is a two-year graduate program located in the Tisch Sc...

Immune hemolytic anemia

... of hope for owners, whose dogs suffer from canine autoimmune hemolytic anemia . ... Immune -Mediated Hemolytic Anemia & Immune -Mediated thrombocytopenia ... Anemia - immune hemolytic . Causes, incidence, and risk factors. Immune hemolytic anemia occurs when antibodies form against the bo...

Hus

...ero and martyr of Christian history. ... Hus was burned at the stake in 1415, ... HUS is characterised by microangiopathic haemolytic anemia, thrombocytopenia and ... In atypical HUS cases with FH mutations, either the sub-optimal activity or the ... Hus was above all a preacher, and scholarly studi...

Fetal

...inal Article from The New England Journal of Medicine -- Fetal Alloimmune thrombocytopenia ... Conclusions Fetal alloimmune thrombocytopenia occurs early ... ...
Thrombocytopenia in Biological News

Lancet study supports new, highly effective treatment for blood disorder

...the U.S. Food and Drug Administration in November 2008 for the treatment of thrombocytopenia in patients with chronic immune (idiopathic) thrombocytopenic purpura who h...safety in populations like the 4 million Americans with hepatitis-C-related thrombocytopenia or patients receiving myelosuppressive chemotherapy. Collaborators on th...

Ireland Cancer Center researchers advance stem cell gene therapy

...blood cell formation) and stem cell engraftment. Dr. Shigemi Matsuyama and colleagues presented a novel way of treating chemotherapy -induced thrombocytopenia (decrease in number of platelets in the blood) using Bax Inhibiting Peptides to rescue the damaged cells. Dr. Keith McCrae and colleagues pres...

Safe and effective therapy discovered for patients with protein-losing enteropathy

...ran sulfate and prevents protein leakage in vitro. However, long-term therapy with anticoagulant heparin has severe side effects, including bleeding, thrombocytopenia and osteoporosis. However, the study also revealed an alternative form of heparin as a potential therapy. By adapting well-established clinical assa...
Thrombocytopenia in Biological Technology

Centocor Ortho Biotech Data to be Presented at American Society of Clinical Oncology (ASCO) Annual Meeting

...DE plus DOXIL vs VELCADE, respectively) included: neutropenia (36% vs 22%), thrombocytopenia (33% vs 28%), anemia (25% vs 21%), fatigue (36% vs 28%), pyrexia (31% vs 22...mm3, 46%; <500/mm3, 11%), anemia (Hb <10 g/dL, 58%; <8 g/dL, 16%), thrombocytopenia (<150,000 platelets/mm3, 61%), nausea (18%), asthenia (7%), fever (8%), ...

ThromboGenics NV: Business Update

...romboGenics for the continued development of Anti-VPAC for the treatment of thrombocytopenia - At the end of February 2009, ThromboGenics was awarded a grant of up to E...enylyl Cyclase-Activating Peptide Receptor 1) antibody for the treatment of thrombocytopenia (low platelet count) after chemotherapy. The grant was received from...

Sanofi-aventis U.S. to Acquire Oral Chronic Lymphocytic Leukemia Treatment

...to intravenously administered fludarabine phosphate have not been performed. The most common adverse reactions include myelosuppression (neutropenia, thrombocytopenia and anemia), fever and chills, infection, and nausea and vomiting. Serious opportunistic infections have occurred in patients with CLL treated with f...

Rigel Announces First Quarter 2009 Financial Results

... to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis thrombocytopenia and asthma, as well as in cancer. This press release contains "forward-looking" statements, including statements related to relating to the timi...

Rigel to Present at Citi's Biotech Day

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. Contact: Ryan Maynard Phone: 650.624.1284 Email: invrel@rigel.com ...

Catalyst Biosciences Expands Scientific Advisory Board With Leading Experts in Protease Therapeutic Discovery and Development

...ntrol the severity of VWD. The lab has also defined mutations in ADAMTS13, an enzyme that processes von Willebrand factor, as the cause of Thrombotic thrombocytopenia Purpura. The laboratory is also searching for genetic modifiers of thrombotic diseases, including the common human mutation Factor V Leiden. Studies...

Poniard Pharmaceuticals Announces New Efficacy and Safety Data from a Phase 2 Picoplatin Trial in Patients with Prostate Cancer

...lone. These data indicate that picoplatin can be safely administered with full-dose docetaxel. Neutropenia was the main hematologic toxicity. thrombocytopenia was less severe and less frequent with picoplatin administered in combination with docetaxel compared with picoplatin administered alone. ...

Cell Therapeutics Exercises Its Option to Sell Interest in Zevalin Joint Venture to Spectrum Pharmaceuticals for $18 Million

...reactions have been reported. The most serious adverse reactions of the Zevalin therapeutic regimen were primarily hematologic, including neutropenia, thrombocytopenia and anemia. Infusion-related toxicities were associated with pre-administration of rituximab. The risk of hematologic toxicity correlated with the deg...

Poniard Pharmaceuticals Announces Positive Tumor Response and Neuropathy Data from Phase 2 Clinical Trial of Picoplatin in Metastatic Colorectal Cancer

...d with no FOLPI-treated patients. Nonhematologic adverse events, including acute gastrointestinal toxicity, were similar between the treatment groups. thrombocytopenia and neutropenia were more frequent and severe with the FOLPI regimen, but manageable. Anti-tumor activity also was similar in the FOLPI and FOLFO...

Rigel to Participate at the RBC Capital Markets Healthcare Conference

...to develop and market our product candidates. Rigel has product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia and asthma, as well as in cancer. Contact: Ryan Maynard Phone: 650.624.1284 Email: invrel@rigel.com " target="_new"> invre...
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