Adding Radiation Therapy To Chemotherapy Improves Survival In Patients With High-risk Breast Cancer
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...Columbia research lifts major hurdle to gene therapy for cancer
Researchers at Columbia University MedicalCenter have discovered a way to overcome one of the major hurdles ingene therapy for cancer: its tendency to kill normal cells in theprocess of eradicating cancer cells.In a new study published in the Jan. 25 issue of the Proceedings of theNational Academy of Sciences (PNAS), the researchers demonstrated thatthe technique works by incorporating it i...Combination therapy boosts effectiveness of telomere-directed cancer cell death
Sometimes apotential target for a drug seems very promising on paper; things areoften very different in reality. Its the case of telomerase inhibitorsto treat cancer; they are supposed to strip the "immortal" (able todivide indefinitely) aspect of cancer cells. Yet, something in the cellseems to block their function, preventing them to inhibit completelythe...Gene therapy converts dead bone graft to new, living tissue
Researchers have created a way to transform the dead bone of a transplanted skeletal graft into living tissue in an experiment involving mice. The advance, which uses gene therapy to stimulate the body into treating the foreign splint as living bone, is a promising development for the thousands of cancer and trauma patients each year who suffer with fragile and failing bone grafts. The findings w...Novel Therapy Tested in Mice Could Chase Away Cat Allergies
A molecule designed to block cat allergies successfully prevented allergic reactions in laboratory mice, as well as in human cells in a test tube, University of California, Los Angeles (UCLA) researchers report in the April issue of Nature Medicine, available online now. In the future, the investigators say, these promising results could lead to a new therapy not only for human cat allergies, but...GPCR SpliceArray Service from ExonHit Therapeutics Inc.
Description:The binding specificity and signaling of the members of the GPCR family are known to be modified by alternative splicing--which has important implications for drug research. With GPCR SpliceArrays you can perform a classical expression profiling and at the same time detect the different alternatively spliced forms of the gene that are expressed in the samples under study. The GPCR SpliceArray mon...Apoptosis Pathway SpliceArrays from ExonHit Therapeutics Inc.
Description:Alternative Splicing plays an important role in the regulation of signaling pathways involved in apoptosis and cell death. Splice variants have been reported that affect both the activation and inhibition of defined apoptotic pathways. With Apoptosis and Cell Death SpliceArrays you can perform a classical expression profiling and at the same time detect the different alternatively spliced forms...Custom Splice Arrays from ExonHit Therapeutics Inc.
Description:Through its SpliceArray service, ExonHit can design custom microarrays to detect alternative splicing events starting with your gene list. Proprietary algorithms are used to identify splice events and design microarray probes from high quality, spliced cDNAs aligned to the human genome. Each splice event contained in a custom SpliceArray is profiled with a patent protected combination of six exo...Ion Channel SpliceArray Service from ExonHit Therapeutics Inc.
Description:The binding specificity and signaling of the members of the GPCR family are known to be modified by alternative splicing--which has important implications for drug research. With GPCR SpliceArrays you can perform a classical expression profiling and at the same time detect the different alternatively spliced forms of the gene that are expressed in the samples under study. The GPCR SpliceArray mon...Microarray expression profiling service from ExonHit Therapeutics Inc.
Description:SpliceArray Services is a microarray service provider that supports industrial and academic researchers. We are a Certified Servive Provider of Agilent, and we provide expression profiling services on all Agilent catalogue arrays. Gene expression reports are delivered via CD....Gender hormones may lend to social disorder therapies
Social disorders such as autism constitute one area where those differences come to the fore: around 80 percent of all autism cases, for example, occur in men. Social play behaviors also differ greatly between the sexes - just about everyone agrees that young boys play "rougher" t...The Genesis of Gendicine: The Story Behind the First Gene Therapy
In this BioPharmInternational exclusiveinterview,SiBionosfounder relates thescience andmanufacture of hiscompanys innovativecancer therapy....TomoTherapy reports 86% revenue jump, $131M net loss in Q1
The company also announced that it has joined a resear...TomoTherapy opens technical training center
The company, which recently raised $213 million in an initial public offering of stock, said engineers, physicists, and radiation technicians are among the professionals who will receive on-sit...Biologist who cloned Dolly the sheep believes therapeutic cloning will gain acceptance
Wilmut, a biologist with the <a href="http://www.re...Cancer Doctors Okays Controversial Prostate Therapy
A controversial treatment for prostate cancer in which radioactive seeds are implanted in the prostate to destroy the tumor received support Friday from doctors writing therapy guidelines for the prestigious 17-hospital National Comprehensive Cancer Network (NCCN) meeting in Ft. Lauderdale, Fla. This type of therapy is known as brachytherapy, the procedure has been performed for years by...New Way to "See" Genes, Evaluate Effectiveness of Gene Therapies Discovered
This technology essentially renders the body transparent and will allow physicians to determine whether gene therapies reach targeted cells and work as they should. "The technology is expected to help patients with cancer and other illnesses, such as cardiovascular disease. The discovery is outlined in the August 2000, issue of the journal Nature Medicine. UCLA researchers plan to tes...Consensus on "Combination Therapy" for Breast Cancer
Breast cancer is the commonest cancer among women in the world. There has been some on going controversy on certain aspects of treatment modalities of this cancer. Besides surgery there are other options to treat the cancer including radiation, chemotherapy and hormonal therapy. Now at a three-day conference at the National Institutes of Health doctors have agreed to a consensus on the c...Acupuncture May Help Chemotherapy Side Effects
Oriental medical practice of Acupuncture along with commonly used medications may help ease the distressing and disabling side effects of chemotherapy for breast cancer patients, if researchers at National Institute of Health (NIH) are to be believed. According to Dr. Joannieshen MD, MPH, research associate at NIH, electro-acupuncture was more effective in controlling vomiting than...Antioxidants protect health tissue in people undergoing radiation therapy.
A recent finding by Indian scientists revealed that two antioxidants in black pepper and turmeric- piperine and curcumin were found to help protect the bacterial DNA from damage by irradiation in test organism. Spices with antioxidants property have radio protective effect and protecting organisms like Escherichia role and Bacillus megaterium organisms (taken for study) against of gamma...VISULAS 690s Photodynamic Therapy Laser System
Description:The VISULAS 690s is the benchmark for photodynamic therapy. As the instrument of choice for the international phase III Visudyne clinical trials, Carl Zeiss has leveraged its 20 year legacy in laser manufacturing to create the photodynamic therapy laser trusted by the world's leading ophthalmologists....2089 TENNIS ELBOW STRAP WITH THERAPEUTIC GEL PAD
Description:An excellent preventative/thera-peutic device for wearing during sports or construction activity. Helps dampen vibration and shock often transmitted during periods of repetitive motion. Provides relief from painful symptoms of tennis elbow. Gel pad is easily detachable from the brush lined encircling strap, and can be cooled or heated for therapy....Monitoring Options Expand for Therapeutic Agents and Drugs of Abuse
In keeping with the recent proliferation of rapid, easy-to-use diagnostic tests, many assays and collection products have entered the marketplace to help clinicians assess dosage appropriateness of therapeutic drugs and to screen for the presence of drugs of abuse. Some of these products require laboratory support while many simple test kits are suitable for point of care use by medical profe...Gene Chips to Detect CYP Variations: A New Step Toward Customized Medical Therapy.
The FDA approval of BiDil for heart failure in African American patients has underscored the concept that two patients can respond differently to the same medication. This concept holds true for a wide variety of everyday medications, and in many cases is due to individual gen...Breast Cancer and HER-2/neu: Diagnostic Tools for Targeted Therapy
Contributing Editor With over 200,000 new cases and 40,000 deaths per year, breast cancer undoubtedly qualifies as one of Americas most serious health problems. Recently, efforts to develop early detection methods and more effective therapy have made important progress. This is particularly...Extracorporeal shockwave therapy
to meet 's <a href="/ ?q=/ Medicine-Definition/ :Manual_of_Style" title=":Manual of Style"...