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Thalassemia in Medical News

StemCyte, Inc. Reaches 1,000th Cord Blood Stem Cell Shipment for Transplant Milestone

...lls have become a viable option to treat a variety of illnesses including leukemia, lymphomas, Autoimmune diseases and Genetic Blood disorders such as thalassemia sickle-cell disease. "With over 20 years of human safety and efficacy data, umbilical cord blood stem cells are emerging as a prime source of ste...

Schering-Plough Completes Enrollment of Boceprevir Registration Studies in Treatment-Naive and Treatment-Experienced HCV Patients

...nant or may become pregnant (see Boxed Warning and Pregnancy section), men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL per min. Pregnancy REBETOL therapy should not be started ...

PEGASYS(R) Proven Effective as Hepatitis C Treatment for Latino Patients, According to Article in The New England Journal of Medicine

...vity to COPEGUS or any of its components, in women who are pregnant, men whose female partners are pregnant, and patients with hemoglobinopathies (eg, thalassemia major, sickle-cell anemia). COPEGUS THERAPY SHOULD NOT BE STARTED UNLESS A REPORT OF A NEGATIVE PREGNANCY TEST HAS BEEN OBTAINED IMMEDIATELY PRI...

Schering-Plough Announces FDA Approval of PEGINTRON(TM) and REBETOL(R) Combination Therapy for Treating Pediatric Hepatitis C

...nant or may become pregnant (see Boxed Warning and Pregnancy section), men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL per min. Pregnancy REBETOL therapy should not be ...

Studies examine quality of care for hospitalized sickle cell disease patients

...ge number of patients who received the therapy over a long period of time. The medical records of 330 patients with sickle cell disease treated at the thalassemia Center of Laikon Hospital in Athens, Greece, over the course of 20 years were retrospectively analyzed. Patients were divided into two groups: a total...

Turning back the Clock in Inherited Anemias

... Reawakening a dormant gene could ease sickle-cell disease and thalassemia (Vocus) December 4, 2008 -- Researchers at Children's Hospital Boston ( www.childrenshospital.org ) and Dana-Farber Cancer ...

Gene Behind Childhood Anemias Found

... Finding could usher in new treatments for sickle cell disease and thalassemia THURSDAY, Dec. 4 (HealthDay News) -- Scientists have identified...ckle cell disease can cause severe pain and eventual organ damage. Treating thalassemia requires frequent blood transfusions and then chelation therapy, which gets...

A Thanksgiving Message From New York Blood Center

...tricken by diagnoses that require frequent blood transfusions for recovery and survival. Among these diseases are: Leukemia and other forms of cancer, thalassemia and aplastic anemias, sickle cell disease, hemophilia and other diseases for which there is no universal cure. Please take a moment from the holiday...

Gioia & New York Blood Center Call for City Aid in Expansion of Mobile Blood Donor Coach Program

...ly low donation rates, but whose blood is critically needed to help those suffering from a variety of health conditions, including sickle cell anemia, thalassemia and leukemia. Statistics show an increase not only in the number of blood drives with the use of the donor coaches but also in the units of blood coll...

BMP Sunstone Announces Official Launch of Ferriprox in PRC

...e that can lead to organ damage and heart failure. thalassemia is particularly prevalent in humid environments, l...on of the 15.0 million people in China who develop thalassemia each year. While many physicians are already aware...e. Gao continued, "Ferriprox is a cost-effective thalassemia treatment, which we believe will result in greater...
Thalassemia in Medical Technology

Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting

...nant or may become pregnant (see Boxed Warning and Pregnancy section), men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL per min. Pregnancy REBETOL therapy should not be started ...

Ground-Breaking Combination of All-Oral Agents Demonstrates Potential as Hepatitis C Treatment Regimen

...vity to COPEGUS or any of its components, in women who are pregnant, men whose female partners are pregnant, and patients with hemoglobinopathies (eg, thalassemia major, sickle-cell anemia). COPEGUS THERAPY SHOULD NOT BE STARTED UNLESS A REPORT OF A NEGATIVE PREGNANCY TEST HAS BEEN OBTAINED IMMEDIATELY PRI...

Roche and Pharmasset Initiate Phase IIb Clinical Trial of R7128, Most Advanced Nucleoside Polymerase Inhibitor in Development for Chronic Hepatitis C

...vity to COPEGUS or any of its components, in women who are pregnant, men whose female partners are pregnant, and patients with hemoglobinopathies (eg, thalassemia major, sickle-cell anemia). COPEGUS THERAPY SHOULD NOT BE STARTED UNLESS A REPORT OF A NEGATIVE PREGNANCY TEST HAS BEEN OBTAINED IMMEDIATELY PRI...

Final Results of Boceprevir Phase II HCV SPRINT-1 Study Showed Significantly Higher SVR Rates Compared to Standard of Care in Treatment-Naive Genotype 1 Hepatitis C Patients

...nant or may become pregnant (see Boxed Warning and Pregnancy section), men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL per min. Pregnancy REBETOL therapy should not be started ...

FDA Approves an Expanded Indication for Peginterferon-Based Combination Therapy for Patients With Chronic Hepatitis C

...nant or may become pregnant (see Boxed Warning and Pregnancy section), men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL per min. Pregnancy REBETOL therapy should not be started unt...

Studies Examine Quality of Care for Hospitalized Sickle Cell Disease Patients and Effective Methods for Detecting Risk of Stroke in Children With This Disorder

...ge number of patients who received the therapy over a long period of time. The medical records of 330 patients with sickle cell disease treated at the thalassemia Center of Laikon Hospital in Athens, Greece, over the course of 20 years were retrospectively analyzed. Patients were divided into two groups: a total...

Schering-Plough Provides Update on Boceprevir Clinical Development and Introduces Potent Next-Generation Oral HCV Protease Inhibitor for Treating Patients With Chronic Hepatitis C

...bavirin or any other component of the product, women who are pregnant, men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL/min. Avoid Pregnancy REBETOL therapy should not b...

Boceprevir Phase II Study Showed High Rate of Sustained Response With 28- and 48-Week Regimens in Genotype 1 Treatment-Naive Hepatitis C Patients

...bavirin or any other component of the product, women who are pregnant, men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL/min. Avoid Pregnancy REBETOL therapy should not be started unti...

Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients

...bavirin or any other component of the product, women who are pregnant, men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL/min. Avoid Pregnancy REBETOL therapy should not be started unti...

Schering-Plough To Initiate Phase III Studies With HCV Protease Inhibitor Boceprevir in Previously Untreated Hepatitis C Patients and Those Who Failed Prior Treatment

...bavirin or any other component of the product, women who are pregnant, men whose female partners are pregnant, patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia), and patients with creatinine clearance less than 50 mL/min. Avoid Pregnancy REBETOL therapy should not be started unti...
Thalassemia in Medical Products

Alpha Thalassemia Analysis

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories
Thalassemia in Medical Definition

Hematopathology

...emia: ( Iron deficiency anemia , Plummer-Vinson syndrome , Pernicious anemia , Megaloblastic anemia ) • Hemolytic anemia : ( G6PD Deficiency , thalassemia , Sickle-cell disease / trait , Hereditary spherocytosis , Hereditary elliptocytosis , Hereditary stomatocytosis , Warm autoimmune hemolytic anem...

Pathology

...emia: ( Iron deficiency anemia , Plummer-Vinson syndrome , Pernicious anemia , Megaloblastic anemia ) • Hemolytic anemia : ( G6PD Deficiency , thalassemia , Sickle-cell disease / trait , Hereditary spherocytosis , Hereditary elliptocytosis , Hereditary stomatocytosis , Warm autoimmune hemolytic anem...
Thalassemia in Medical Dictionary

Thalassemia

Thalassemia — Comprehensive overview covers symptoms, causes, treatment of this inherited blood disorder. ... you have mild thalassemia , you may not need ... thalassemia ( ′thalə′sēmēə ) ( medicine ) A hereditary form of hemolytic anemia resulting from a defective synthe...

Sickle Cell

... and joints. ... Sickle cell disease is an inherited blood disorder characterized by defective hemoglobin. ... an inheritance of both the thalassemia and sickle cell genes. ... InteliHealth - Featuring Harvard Medical School's consumer ... These abnormally shaped cells cause the symptoms an...

Hypercoagulable states

...est and treat, ... ... diabetes mellitus, and other chronic hypercoagulable states . ... The mechanism of the hypercoagulable state in thalassemia has not been fully elucidated. ... Hypercoagulable states - Overview, Hypercoagulable states are conditions that ... Hypercoagulable s...

Hemoglobinuria

... nocturnal hemoglobinuria . Sickle cell anemia. thalassemia ... Hemoglobinuria information including sym... nocturnal hemoglobinuria . Sickle cell anemia. thalassemia ... Hemoglobinuria Information from Drugs.co... nocturnal hemoglobinuria . Sickle cell anemia. thalassemia ... Hemoglobinuria ... This is called hemog...

Blood disorders

.... are specialists in blood disorders , are often asked to ... With this Blood disorder , patients not only have more red cells, that is, ... thalassemia - A group of fatal genetic Blood disorders . ... ...
Thalassemia in Biological News

Avoiding Spleen Removal for Cooley's Anemia SufferersAvoiding spleen removal for Cooley's anemia suf

... Mutations in the beta globin gene can lead to thalassemia or sickle-cell anemia. thalassemia and sickle-cell anemia are quite common, not only ...threatening blood clots. Splenectomy is common for thalassemia patients because their red blood cells are cripple...

Birth defects: 8 million annually worldwide

...percent of all such birth defects in 2001: congenital heart defects (1,040,865 births); neural tube defects (323,904 births); the hemoglobin disorders thalassemia and sickle cell disease (307,897 births); Down syndrome (217,293 births); and G6PD deficiency (177,032 births). The database includes only birth de...
Thalassemia in Biological Technology

Therapure Biopharma Inc. Announces Manufacturing Agreement with Biomedical Frontiers Incorporated -- Contract will Support Phase II Trials for Thalassemia Treatment

Thomas Wellner, President and CEO of Therapure Biopharma Inc. today announced that the Company has signed a biomanufacturing services agreement with Minnesota-based Biomedical Frontiers Incorporated for the production of an iron chelating agent used in the treatment of thalassemia, an inherited b...

BMP Sunstone Reports Second Quarter 2008 Financial Results

... treatment for iron overload in the bloodstream which is often associated with thalassemia, a disease that can lead to organ damage and heart failure. thalassemia is particularly prevalent in humid environments, like that in Southern China, where it is estimated that 7-8% of the population needs treatment for th...
Thalassemia in Biological Definition

Blood

...f the blood-forming tissues. Major blood loss, whether traumatic or not (e.g. during surgery), as well as certain blood diseases like anemia and thalassemia , can require blood transfusion . Several countries have blood banks to fill the demand for transfusable blood. A person receiving a blood transfus...

Full blood count

... as microcytic or macrocytic based on whether this value is above or below the expected normal range. Other conditions that can affect MCV include thalassemia and reticulocytosis . Mean cell hemoglobin (MCH) - the average amount of hemoglobin per red blood cell, in picograms . Mean cell hemoglobin ...

Eugenics

...asures" or to submit to sterilization. A similar screening policy (including pre-natal screening and abortion ) intended to reduce the incidence of thalassemia exists on both sides of the island of Cyprus . Since the program's implementation in the 1970s , it has reduced the ratio of children born with th...

Malaria

...ll anemia is particularly common among people of African origin. There is a theory that another hemoglobin mutation, which causes the genetic disease thalassemia , may also give its carriers an enhanced immunity to malaria. Another disease that gives protection against malaria is glucose-6-phosphate dehydrog...

Promoter

...Med . 160 (3), 919-922. Beta-Thalassemia case study: Kulozik, A.E.; Bellan-Koch, A.; Bail, S.; Kohne, E.; and Kleihauer, E. (1991). thalassemia intermedia: moderate reduction of beta globin gene transcriptional activity by a novel mutation of the proximal CACCC promoter element . Blood . 7...
Thalassemia in Biological Dictionary

Thalassemia

Thalassemia is an inherited autosomal recessive blood disease. In thalassemia , the genetic defect results in reduced rate of synthesis of one of the globin chains that make up hemoglobin. Reduced synthesis of one of the... Thalassemias (thal-a-SE-me-ahs) are inherited blood disorders. .....
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